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<!--Generated by DataTracks Rainbow version 3.5 for Toppan Merrill on 21-February-2026 [05:37:53] {AM}-->
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<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_AllianceRevenue" xlink:label="loc_azn_AllianceRevenue" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AllianceRevenue" xml:lang="en">Alliance Revenue</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_AllianceRevenue" xlink:to="lab_azn_AllianceRevenue" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_AllianceRevenue" xml:lang="en">Represents the amount of alliance revenue.</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_CollaborationRevenue" xlink:label="loc_azn_CollaborationRevenue" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_CollaborationRevenue" xml:lang="en">Collaboration Revenue</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_CollaborationRevenue" xlink:to="lab_azn_CollaborationRevenue" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_CollaborationRevenue" xml:lang="en">The amount of revenue arising from transactions involving the Company's medicines as well as medicine the Company has acquired an interest in. Such income included upfront consideration, milestones receipts and royalties, as well as other income from collaborations.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_GrossProfit" xlink:label="loc_ifrs-full_GrossProfit" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_GrossProfit" xml:lang="en">Gross profit</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_GrossProfit" xlink:to="lab_ifrs-full_GrossProfit" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_IncomeTaxExpenseContinuingOperations" xlink:label="loc_ifrs-full_IncomeTaxExpenseContinuingOperations" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxExpenseContinuingOperations" xml:lang="en">Tax expense (income)</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxExpenseContinuingOperations" xlink:to="lab_ifrs-full_IncomeTaxExpenseContinuingOperations" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_GainsCostsOfHedgingBeforeTax" xlink:label="loc_azn_GainsCostsOfHedgingBeforeTax" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_GainsCostsOfHedgingBeforeTax" xml:lang="en">Gains Costs Of Hedging Before Tax</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_GainsCostsOfHedgingBeforeTax" xlink:to="lab_azn_GainsCostsOfHedgingBeforeTax" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_GainsCostsOfHedgingBeforeTax" xml:lang="en">The amount of gains (cost) of hedging.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" xlink:label="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" xml:lang="en">Income tax relating to components of other comprehensive income that will be reclassified to profit or loss</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" xlink:to="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" xlink:label="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" xml:lang="en">Income tax relating to components of other comprehensive income that will not be reclassified to profit or loss</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" xlink:to="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_OtherComprehensiveIncomeGainsLossesOnExchangeDifferencesOnLiabilitiesDesignatedInNetInvestmentHedgesBeforeTax" xlink:label="loc_azn_OtherComprehensiveIncomeGainsLossesOnExchangeDifferencesOnLiabilitiesDesignatedInNetInvestmentHedgesBeforeTax" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_OtherComprehensiveIncomeGainsLossesOnExchangeDifferencesOnLiabilitiesDesignatedInNetInvestmentHedgesBeforeTax" xml:lang="en">Other Comprehensive Income Gains Losses On Exchange Differences On Liabilities Designated In Net Investment Hedges Before Tax</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_OtherComprehensiveIncomeGainsLossesOnExchangeDifferencesOnLiabilitiesDesignatedInNetInvestmentHedgesBeforeTax" xlink:to="lab_azn_OtherComprehensiveIncomeGainsLossesOnExchangeDifferencesOnLiabilitiesDesignatedInNetInvestmentHedgesBeforeTax" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_OtherComprehensiveIncomeGainsLossesOnExchangeDifferencesOnLiabilitiesDesignatedInNetInvestmentHedgesBeforeTax" xml:lang="en">Other comprehensive income gains losses on exchange differences on liabilities designated in net investment hedges before tax.</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_ProductRevenue" xlink:label="loc_azn_ProductRevenue" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_ProductRevenue" xml:lang="en">Product Revenue</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_ProductRevenue" xlink:to="lab_azn_ProductRevenue" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_ProductRevenue" xml:lang="en">The amount of revenue arising from the sale of goods and alliance revenue.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_ResearchAndDevelopmentExpense" xlink:label="loc_ifrs-full_ResearchAndDevelopmentExpense" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_ResearchAndDevelopmentExpense" xml:lang="en">Research and development expense</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_ResearchAndDevelopmentExpense" xlink:to="lab_ifrs-full_ResearchAndDevelopmentExpense" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_SellingGeneralAndAdministrativeExpense" xlink:label="loc_ifrs-full_SellingGeneralAndAdministrativeExpense" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_SellingGeneralAndAdministrativeExpense" xml:lang="en">Selling, general and administrative costs</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_SellingGeneralAndAdministrativeExpense" xlink:to="lab_ifrs-full_SellingGeneralAndAdministrativeExpense" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xlink:label="loc_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xml:lang="en">Other Reserves Other Than Merger And Capital Redemption Reserve</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xlink:to="lab_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xml:lang="en">A component of equity representing reserves within equity, not including merger, capital redemption reserve and retained earnings.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" xlink:label="loc_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" xml:lang="en">Current borrowings and current portion of non-current borrowings</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" xlink:to="lab_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentDerivativeFinancialLiabilities" xlink:label="loc_ifrs-full_CurrentDerivativeFinancialLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentDerivativeFinancialLiabilities" xml:lang="en">Current derivative financial liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentDerivativeFinancialLiabilities" xlink:to="lab_ifrs-full_CurrentDerivativeFinancialLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentLeaseLiabilities" xlink:label="loc_ifrs-full_CurrentLeaseLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentLeaseLiabilities" xml:lang="en">Current lease liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentLeaseLiabilities" xlink:to="lab_ifrs-full_CurrentLeaseLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentLiabilities" xlink:label="loc_ifrs-full_CurrentLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:label="lab_ifrs-full_CurrentLiabilities" xml:lang="en">Total current liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentLiabilities" xlink:to="lab_ifrs-full_CurrentLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentProvisions" xlink:label="loc_ifrs-full_CurrentProvisions" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentProvisions" xml:lang="en">Current provisions</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentProvisions" xlink:to="lab_ifrs-full_CurrentProvisions" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentTaxLiabilitiesCurrent" xlink:label="loc_ifrs-full_CurrentTaxLiabilitiesCurrent" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentTaxLiabilitiesCurrent" xml:lang="en">Current tax liabilities, current</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentTaxLiabilitiesCurrent" xlink:to="lab_ifrs-full_CurrentTaxLiabilitiesCurrent" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_TradeAndOtherCurrentPayables" xlink:label="loc_ifrs-full_TradeAndOtherCurrentPayables" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_TradeAndOtherCurrentPayables" xml:lang="en">Trade and other current payables</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_TradeAndOtherCurrentPayables" xlink:to="lab_ifrs-full_TradeAndOtherCurrentPayables" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_Liabilities" xlink:label="loc_ifrs-full_Liabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:label="lab_ifrs-full_Liabilities" xml:lang="en">Total liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_Liabilities" xlink:to="lab_ifrs-full_Liabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CurrentTaxLiabilitiesNoncurrent" xlink:label="loc_ifrs-full_CurrentTaxLiabilitiesNoncurrent" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentTaxLiabilitiesNoncurrent" xml:lang="en">Current tax liabilities, non-current</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentTaxLiabilitiesNoncurrent" xlink:to="lab_ifrs-full_CurrentTaxLiabilitiesNoncurrent" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_DeferredTaxLiabilities" xlink:label="loc_ifrs-full_DeferredTaxLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_DeferredTaxLiabilities" xml:lang="en">Deferred tax liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_DeferredTaxLiabilities" xlink:to="lab_ifrs-full_DeferredTaxLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_LongtermBorrowings" xlink:label="loc_ifrs-full_LongtermBorrowings" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_LongtermBorrowings" xml:lang="en">Non-current portion of non-current borrowings</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_LongtermBorrowings" xlink:to="lab_ifrs-full_LongtermBorrowings" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NoncurrentDerivativeFinancialLiabilities" xlink:label="loc_ifrs-full_NoncurrentDerivativeFinancialLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentDerivativeFinancialLiabilities" xml:lang="en">Non-current derivative financial liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentDerivativeFinancialLiabilities" xlink:to="lab_ifrs-full_NoncurrentDerivativeFinancialLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NoncurrentLeaseLiabilities" xlink:label="loc_ifrs-full_NoncurrentLeaseLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentLeaseLiabilities" xml:lang="en">Non-current lease liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentLeaseLiabilities" xlink:to="lab_ifrs-full_NoncurrentLeaseLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NoncurrentLiabilities" xlink:label="loc_ifrs-full_NoncurrentLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:label="lab_ifrs-full_NoncurrentLiabilities" xml:lang="en">Total non-current liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentLiabilities" xlink:to="lab_ifrs-full_NoncurrentLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NoncurrentPayables" xlink:label="loc_ifrs-full_NoncurrentPayables" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentPayables" xml:lang="en">Trade and other non-current payables</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentPayables" xlink:to="lab_ifrs-full_NoncurrentPayables" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NoncurrentProvisions" xlink:label="loc_ifrs-full_NoncurrentProvisions" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentProvisions" xml:lang="en">Non-current provisions</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentProvisions" xlink:to="lab_ifrs-full_NoncurrentProvisions" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" xlink:label="loc_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" xml:lang="en">Non-current net defined benefit liability</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" xlink:to="lab_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_NetAssetsLiabilities" xlink:label="loc_ifrs-full_NetAssetsLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_NetAssetsLiabilities" xml:lang="en">Net assets (liabilities)</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NetAssetsLiabilities" xlink:to="lab_ifrs-full_NetAssetsLiabilities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" xlink:label="loc_ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" xml:lang="en">Dividends recognised as distributions to non-controlling interests</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" xlink:to="lab_ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xlink:label="loc_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xml:lang="en">Dividends Recognised As Distributions To Owners Of Parent Net Of Forfeiture</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xml:lang="en">Dividends Recognised As Distributions To Owners Of Parent Net Of Forfeiture</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xlink:to="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xml:lang="en">The amount of dividends, net of forfeitures, recognised as distributions to owners of the parent.</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xlink:label="loc_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xml:lang="en">Increase Decrease Through Transfer Between Other Reserves And Retained Earnings Equity</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xlink:to="lab_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xml:lang="en">The increase (decrease) in equity resulting from transfers between the other reserves and retained earnings.</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_SettlementOfSharePlanAwardsEquity" xlink:label="loc_azn_SettlementOfSharePlanAwardsEquity" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_SettlementOfSharePlanAwardsEquity" xml:lang="en">Settlement Of Share Plan Awards Equity</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_SettlementOfSharePlanAwardsEquity" xlink:to="lab_azn_SettlementOfSharePlanAwardsEquity" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_SettlementOfSharePlanAwardsEquity" xml:lang="en">Amount of settlement of share plan awards.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xlink:label="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="lab_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xml:lang="en">Cash and cash equivalents at end of period</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="lab_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xml:lang="en">Cash and cash equivalents at beginning of period</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xlink:to="lab_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_CashFlowsFromUsedInFinancingActivities" xml:lang="en">Net cash flows from (used in) financing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities" xlink:to="lab_ifrs-full_CashFlowsFromUsedInFinancingActivities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_DividendsPaidClassifiedAsFinancingActivities" xlink:label="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" xml:lang="en">Dividends paid, classified as financing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" xlink:to="lab_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xlink:label="loc_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xml:lang="en">Hedge Contracts Relating To Dividend Payments Receipts Classified As Financing Activities</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xml:lang="en">Hedge Contracts Relating To Dividend Payments Receipts Classified As Financing Activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xlink:to="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xml:lang="en">The cash inflow or outflow from hedge contracts relating to dividend payments (receipts).</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_PaymentOfSharePurchaseLiabilities" xlink:label="loc_azn_PaymentOfSharePurchaseLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_PaymentOfSharePurchaseLiabilities" xml:lang="en">Payment Of Share Purchase Liabilities</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_PaymentOfSharePurchaseLiabilities" xml:lang="en">Payment Of Share Purchase Liabilities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_PaymentOfSharePurchaseLiabilities" xlink:to="lab_azn_PaymentOfSharePurchaseLiabilities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_PaymentOfSharePurchaseLiabilities" xml:lang="en">Payment of share purchase liabilities.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xlink:label="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xml:lang="en">Payments of lease liabilities, classified as financing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xlink:to="lab_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xlink:label="loc_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xml:lang="en">Repayments of borrowings, classified as financing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xlink:to="lab_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_CashFlowsFromUsedInInvestingActivities" xml:lang="en">Net cash flows from (used in) investing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities" xlink:to="lab_ifrs-full_CashFlowsFromUsedInInvestingActivities" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xlink:label="loc_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">Contingent Consideration Payment Business Combinations Classified As Investing Activities</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">Contingent Consideration Payment Business Combinations Classified As Investing Activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xlink:to="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">The amount of contingent consideration paid on account of business combinations.</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xlink:label="loc_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xml:lang="en">Inflows Outflows Of Cash Related To Profit Participation Liability Classified As Investing Activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xlink:to="lab_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xml:lang="en">Inflows (outflows) of cash related to profit participation liability, classified as investing activities.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" xml:lang="en">Other cash payments to acquire interests in joint ventures, classified as investing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xlink:label="loc_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xml:lang="en">Payments Upon Vesting Of Employee Share Awards Attributable To Business Combinations</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xml:lang="en">Payments Upon Vesting Of Employee Share Awards Attributable To Business Combinations</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xlink:to="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xml:lang="en">Payments upon vesting of employee share awards attributable to business combinations.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xml:lang="en">Purchase of intangible assets, classified as investing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" xml:lang="en">Purchase of other long-term assets, classified as investing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" />
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xml:lang="en">Purchase of property, plant and equipment, classified as investing activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" xlink:label="loc_azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">Upfront Payments On Business Combinations Classified As Investing Activities</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">Upfront Payments On Business Combinations Classified As Investing Activities</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" xlink:to="lab_azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_UpfrontPaymentsOnBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">The cash outflow from upfront payments on business combinations, classified as investing activities.</label>
<loc xlink:type="locator" xlink:href="https://xbrl.ifrs.org/taxonomy/2024-03-27/full_ifrs/full_ifrs-cor_2024-03-27.xsd#ifrs-full_AdjustmentsForFinanceIncomeCost" xlink:label="loc_ifrs-full_AdjustmentsForFinanceIncomeCost" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_AdjustmentsForFinanceIncomeCost" xml:lang="en">Adjustments for finance income (cost)</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_AdjustmentsForFinanceIncomeCost" xlink:to="lab_ifrs-full_AdjustmentsForFinanceIncomeCost" />
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xlink:label="loc_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xml:lang="en">Adjustments For Increase Decrease In Trade Other Payables And Provisions</label>
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xml:lang="en">Adjustments For Increase Decrease In Trade Other Payables And Provisions</label>
<labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xlink:to="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xml:lang="en">Adjustments for increase (decrease) in trade, other payables and provisions to reconcile profit (loss) to net cash flow from (used in) operating activities.</label>
<loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2025-12-31.xsd#azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" xlink:label="loc_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" xml:lang="en">Adjustments For Losses Gains On Disposal Of Intangible Asset</label>
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