﻿<?xml version="1.0" encoding="utf-8"?>
<!--Generated by DataTracks Rainbow version 3.5 for Toppan Merrill on 21-February-2023 [09:18:57] {AM}-->
<linkbase xmlns="http://www.xbrl.org/2003/linkbase" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" roleURI="http://www.xbrl.org/2009/role/negatedLabel" />
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" />
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" />
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" />
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" />
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" />
  <roleRef xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" roleURI="http://www.xbrl.org/2009/role/netLabel" />
  <labelLink xlink:type="extended" xlink:role="http://www.xbrl.org/2003/role/link">
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_CollaborationRevenue" xlink:label="loc_azn_CollaborationRevenue" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_CollaborationRevenue" xml:lang="en">Collaboration Revenue</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_CollaborationRevenue" xlink:to="lab_azn_CollaborationRevenue" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_CollaborationRevenue" xml:lang="en">The amount of revenue arising from transactions involving the Company's medicines as well as medicine the Company has acquired an interest in. Such income included upfront consideration, milestones receipts and royalties, as well as other income from collaborations.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" xlink:label="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" xml:lang="en">Income tax relating to components of other comprehensive income that will not be reclassified to profit or loss</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" xlink:to="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_CostOfHedgingBeforeTax" xlink:label="loc_azn_CostOfHedgingBeforeTax" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_CostOfHedgingBeforeTax" xml:lang="en">Cost Of Hedging Before Tax</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_CostOfHedgingBeforeTax" xml:lang="en">Gains/(costs) of hedging</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_CostOfHedgingBeforeTax" xlink:to="lab_azn_CostOfHedgingBeforeTax" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_CostOfHedgingBeforeTax" xml:lang="en">The amount of cost of hedging.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_GainsLossesOnExchangeDifferencesOnConsolidationBeforeTax" xlink:label="loc_azn_GainsLossesOnExchangeDifferencesOnConsolidationBeforeTax" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_GainsLossesOnExchangeDifferencesOnConsolidationBeforeTax" xml:lang="en">Gains Losses On Exchange Differences On Consolidation Before Tax</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_GainsLossesOnExchangeDifferencesOnConsolidationBeforeTax" xlink:to="lab_azn_GainsLossesOnExchangeDifferencesOnConsolidationBeforeTax" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_GainsLossesOnExchangeDifferencesOnConsolidationBeforeTax" xml:lang="en">The gains (losses) recognised in other comprehensive income on exchange differences on the consolidation of financial statements of foreign operations, before tax.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_GainsLossesOnExchangeDifferenceHedgesOfNetInvestmentsInForeignOperationsBeforeTax" xlink:label="loc_azn_GainsLossesOnExchangeDifferenceHedgesOfNetInvestmentsInForeignOperationsBeforeTax" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_GainsLossesOnExchangeDifferenceHedgesOfNetInvestmentsInForeignOperationsBeforeTax" xml:lang="en">Gains Losses On Exchange Difference Hedges Of Net Investments In Foreign Operations Before Tax</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_GainsLossesOnExchangeDifferenceHedgesOfNetInvestmentsInForeignOperationsBeforeTax" xlink:to="lab_azn_GainsLossesOnExchangeDifferenceHedgesOfNetInvestmentsInForeignOperationsBeforeTax" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_GainsLossesOnExchangeDifferenceHedgesOfNetInvestmentsInForeignOperationsBeforeTax" xml:lang="en">The gains (losses) recognised in other comprehensive income on exchange difference hedges of net investments in foreign operations, before tax.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" xlink:label="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" xml:lang="en">Income tax relating to components of other comprehensive income that will be reclassified to profit or loss</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" xlink:to="lab_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_GrossProfit" xlink:label="loc_ifrs-full_GrossProfit" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_GrossProfit" xml:lang="en">Gross profit</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_GrossProfit" xlink:to="lab_ifrs-full_GrossProfit" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_ResearchAndDevelopmentExpense" xlink:label="loc_ifrs-full_ResearchAndDevelopmentExpense" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_ResearchAndDevelopmentExpense" xml:lang="en">Research and development expense</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_ResearchAndDevelopmentExpense" xlink:to="lab_ifrs-full_ResearchAndDevelopmentExpense" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod" xlink:label="loc_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod" xml:lang="en">Share of profit (loss) of associates and joint ventures accounted for using equity method</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod" xlink:to="lab_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_IncomeTaxExpenseContinuingOperations" xlink:label="loc_ifrs-full_IncomeTaxExpenseContinuingOperations" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxExpenseContinuingOperations" xml:lang="en">Tax expense (income)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxExpenseContinuingOperations" xlink:to="lab_ifrs-full_IncomeTaxExpenseContinuingOperations" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_SellingGeneralAndAdministrativeExpense" xlink:label="loc_ifrs-full_SellingGeneralAndAdministrativeExpense" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_SellingGeneralAndAdministrativeExpense" xml:lang="en">Selling, general and administrative costs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_SellingGeneralAndAdministrativeExpense" xlink:to="lab_ifrs-full_SellingGeneralAndAdministrativeExpense" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_ProfitAttributableToAbstract" xlink:label="loc_azn_ProfitAttributableToAbstract" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_ProfitAttributableToAbstract" xml:lang="en">Profit Attributable To [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_ProfitAttributableToAbstract" xlink:to="lab_azn_ProfitAttributableToAbstract" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_ProfitAttributableToAbstract" xml:lang="en">Profit attributable to: [Abstract].</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_TradeAndOtherCurrentPayables" xlink:label="loc_ifrs-full_TradeAndOtherCurrentPayables" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_TradeAndOtherCurrentPayables" xml:lang="en">Trade and other current payables</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_TradeAndOtherCurrentPayables" xlink:to="lab_ifrs-full_TradeAndOtherCurrentPayables" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CurrentLeaseLiabilities" xlink:label="loc_ifrs-full_CurrentLeaseLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentLeaseLiabilities" xml:lang="en">Current lease liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentLeaseLiabilities" xlink:to="lab_ifrs-full_CurrentLeaseLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" xlink:label="loc_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" xml:lang="en">Current borrowings and current portion of non-current borrowings</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" xlink:to="lab_ifrs-full_CurrentBorrowingsAndCurrentPortionOfNoncurrentBorrowings" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CurrentDerivativeFinancialLiabilities" xlink:label="loc_ifrs-full_CurrentDerivativeFinancialLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentDerivativeFinancialLiabilities" xml:lang="en">Current derivative financial liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentDerivativeFinancialLiabilities" xlink:to="lab_ifrs-full_CurrentDerivativeFinancialLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CurrentProvisions" xlink:label="loc_ifrs-full_CurrentProvisions" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentProvisions" xml:lang="en">Current provisions</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentProvisions" xlink:to="lab_ifrs-full_CurrentProvisions" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CurrentLiabilities" xlink:label="loc_ifrs-full_CurrentLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:label="lab_ifrs-full_CurrentLiabilities" xml:lang="en">Total current liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentLiabilities" xlink:to="lab_ifrs-full_CurrentLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CurrentTaxLiabilities" xlink:label="loc_ifrs-full_CurrentTaxLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CurrentTaxLiabilities" xml:lang="en">Current tax liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CurrentTaxLiabilities" xlink:to="lab_ifrs-full_CurrentTaxLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_DeferredTaxLiabilities" xlink:label="loc_ifrs-full_DeferredTaxLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_DeferredTaxLiabilities" xml:lang="en">Deferred tax liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_DeferredTaxLiabilities" xlink:to="lab_ifrs-full_DeferredTaxLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" xlink:label="loc_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" xml:lang="en">Non-current net defined benefit liability</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" xlink:to="lab_ifrs-full_NoncurrentRecognisedLiabilitiesDefinedBenefitPlan" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NoncurrentProvisions" xlink:label="loc_ifrs-full_NoncurrentProvisions" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentProvisions" xml:lang="en">Non-current provisions</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentProvisions" xlink:to="lab_ifrs-full_NoncurrentProvisions" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NoncurrentPayables" xlink:label="loc_ifrs-full_NoncurrentPayables" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentPayables" xml:lang="en">Trade and other non-current payables</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentPayables" xlink:to="lab_ifrs-full_NoncurrentPayables" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NoncurrentLiabilities" xlink:label="loc_ifrs-full_NoncurrentLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:label="lab_ifrs-full_NoncurrentLiabilities" xml:lang="en">Total non-current liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentLiabilities" xlink:to="lab_ifrs-full_NoncurrentLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_LongtermBorrowings" xlink:label="loc_ifrs-full_LongtermBorrowings" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_LongtermBorrowings" xml:lang="en">Non-current portion of non-current borrowings</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_LongtermBorrowings" xlink:to="lab_ifrs-full_LongtermBorrowings" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NoncurrentLeaseLiabilities" xlink:label="loc_ifrs-full_NoncurrentLeaseLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentLeaseLiabilities" xml:lang="en">Non-current lease liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentLeaseLiabilities" xlink:to="lab_ifrs-full_NoncurrentLeaseLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NoncurrentDerivativeFinancialLiabilities" xlink:label="loc_ifrs-full_NoncurrentDerivativeFinancialLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_NoncurrentDerivativeFinancialLiabilities" xml:lang="en">Non-current derivative financial liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NoncurrentDerivativeFinancialLiabilities" xlink:to="lab_ifrs-full_NoncurrentDerivativeFinancialLiabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_Liabilities" xlink:label="loc_ifrs-full_Liabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:label="lab_ifrs-full_Liabilities" xml:lang="en">Total liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_Liabilities" xlink:to="lab_ifrs-full_Liabilities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_NetAssetsLiabilities" xlink:label="loc_ifrs-full_NetAssetsLiabilities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_NetAssetsLiabilities" xml:lang="en">Net assets (liabilities)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_NetAssetsLiabilities" xlink:to="lab_ifrs-full_NetAssetsLiabilities" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_CapitalAndReservesAttributableToEquityHoldersOfTheCompanyAbstract" xlink:label="loc_azn_CapitalAndReservesAttributableToEquityHoldersOfTheCompanyAbstract" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_CapitalAndReservesAttributableToEquityHoldersOfTheCompanyAbstract" xml:lang="en">Capital And Reserves Attributable To Equity Holders Of The Company [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_CapitalAndReservesAttributableToEquityHoldersOfTheCompanyAbstract" xlink:to="lab_azn_CapitalAndReservesAttributableToEquityHoldersOfTheCompanyAbstract" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_CapitalAndReservesAttributableToEquityHoldersOfTheCompanyAbstract" xml:lang="en">Capital and reserves attributable to equity holders of the company [Abstract].</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xlink:label="loc_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xml:lang="en">Other Reserves Other Than Merger And Capital Redemption Reserve</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xlink:to="lab_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_OtherReservesOtherThanMergerAndCapitalRedemptionReserve" xml:lang="en">A component of equity representing reserves within equity, not including merger, capital redemption reserve and retained earnings.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xlink:label="loc_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xml:lang="en">Increase Decrease Through Transfer Between Other Reserves And Retained Earnings Equity</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xlink:to="lab_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_IncreaseDecreaseThroughTransferBetweenOtherReservesAndRetainedEarningsEquity" xml:lang="en">The increase (decrease) in equity resulting from transfers between the other reserves and retained earnings.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_TransactionsWithOwnersAbstract" xlink:label="loc_azn_TransactionsWithOwnersAbstract" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_TransactionsWithOwnersAbstract" xml:lang="en">Transactions With Owners [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_TransactionsWithOwnersAbstract" xlink:to="lab_azn_TransactionsWithOwnersAbstract" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_TransactionsWithOwnersAbstract" xml:lang="en">Transactions with owners [Abstract].</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" xlink:label="loc_azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" xml:lang="en">Issue Of Replacement Alexion Share Awards Upon Acquisition</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" xml:lang="en">Issue Of Replacement Alexion Share Awards Upon Acquisition</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" xlink:to="lab_azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_IssueOfReplacementAlexionShareAwardsUponAcquisition" xml:lang="en">Issue of replacement Alexion share awards upon
acquisition.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xlink:label="loc_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xml:lang="en">Dividends Recognised As Distributions To Owners Of Parent Net Of Forfeiture</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xml:lang="en">Dividends Recognised As Distributions To Owners Of Parent Net Of Forfeiture</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xlink:to="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_DividendsRecognisedAsDistributionsToOwnersOfParentNetOfForfeiture" xml:lang="en">The amount of dividends, net of forfeitures, recognised as distributions to owners of the parent.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_SettlementOfSharePlanAwardsEquity" xlink:label="loc_azn_SettlementOfSharePlanAwardsEquity" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_SettlementOfSharePlanAwardsEquity" xml:lang="en">Settlement Of Share Plan Awards Equity</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_SettlementOfSharePlanAwardsEquity" xlink:to="lab_azn_SettlementOfSharePlanAwardsEquity" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_SettlementOfSharePlanAwardsEquity" xml:lang="en">Amount of settlement of share plan awards.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_InAccordanceWithIfric23Member" xlink:label="loc_azn_InAccordanceWithIfric23Member" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_InAccordanceWithIfric23Member" xml:lang="en">In Accordance With Ifric 23 [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_InAccordanceWithIfric23Member" xlink:to="lab_azn_InAccordanceWithIfric23Member" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_InAccordanceWithIfric23Member" xml:lang="en">This member stands for the information reported in accordance with IFRIC 23.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_AcertaPharmaBvMember" xlink:label="loc_azn_AcertaPharmaBvMember" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AcertaPharmaBvMember" xml:lang="en">Acerta Pharma Bv [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_AcertaPharmaBvMember" xlink:to="lab_azn_AcertaPharmaBvMember" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_AcertaPharmaBvMember" xml:lang="en">Represents information relating to Acerta Pharma B.V and its subsidiaries.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_CaelumBiosciencesMember" xlink:label="loc_azn_CaelumBiosciencesMember" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_CaelumBiosciencesMember" xml:lang="en">Caelum Biosciences [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_CaelumBiosciencesMember" xlink:to="lab_azn_CaelumBiosciencesMember" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_CaelumBiosciencesMember" xml:lang="en">Caelum biosciences member.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_AlexionPharmaceuticalsIncMember" xlink:label="loc_azn_AlexionPharmaceuticalsIncMember" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AlexionPharmaceuticalsIncMember" xml:lang="en">Alexion Pharmaceuticals Inc [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_AlexionPharmaceuticalsIncMember" xlink:to="lab_azn_AlexionPharmaceuticalsIncMember" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_AlexionPharmaceuticalsIncMember" xml:lang="en">Alexion pharmaceuticals inc member.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" xlink:label="loc_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" xml:lang="en">Adjustments For Losses Gains On Disposal Of Intangible Asset</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" xlink:to="lab_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_AdjustmentsForLossesGainsOnDisposalOfIntangibleAsset" xml:lang="en">Adjustments for losses (gains) on disposal of intangible assets to reconcile profit (loss) to net cash flow from (used in) operating activities.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_ContingentConsiderationFairValueMovement" xlink:label="loc_azn_ContingentConsiderationFairValueMovement" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_ContingentConsiderationFairValueMovement" xml:lang="en">Contingent Consideration Fair Value Movement</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_ContingentConsiderationFairValueMovement" xlink:to="lab_azn_ContingentConsiderationFairValueMovement" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_ContingentConsiderationFairValueMovement" xml:lang="en">Adjustment of contingent consideration due to change in fair value.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_FinanceIncomeCost" xlink:label="loc_ifrs-full_FinanceIncomeCost" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_FinanceIncomeCost" xml:lang="en">Finance income (cost)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_FinanceIncomeCost" xlink:to="lab_ifrs-full_FinanceIncomeCost" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_InterestPaidClassifiedAsOperatingActivities" xlink:label="loc_ifrs-full_InterestPaidClassifiedAsOperatingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_InterestPaidClassifiedAsOperatingActivities" xml:lang="en">Interest paid, classified as operating activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_InterestPaidClassifiedAsOperatingActivities" xlink:to="lab_ifrs-full_InterestPaidClassifiedAsOperatingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperations" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperations" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_CashFlowsFromUsedInOperations" xml:lang="en">Net cash flows from (used in) operations</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperations" xlink:to="lab_ifrs-full_CashFlowsFromUsedInOperations" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities" xlink:label="loc_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities" xml:lang="en">Income taxes paid (refund), classified as operating activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities" xlink:to="lab_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_CashFlowsFromUsedInOperatingActivities" xml:lang="en">Net cash flows from (used in) operating activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities" xlink:to="lab_ifrs-full_CashFlowsFromUsedInOperatingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates" xlink:label="loc_ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates" xml:lang="en">Adjustments for gain (loss) on disposal of investments in subsidiaries, joint ventures and associates</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates" xlink:to="lab_ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xlink:label="loc_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xml:lang="en">Adjustments For Increase Decrease In Trade Other Payables And Provisions</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xlink:to="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_AdjustmentsForIncreaseDecreaseInTradeOtherPayablesAndProvisions" xml:lang="en">Adjustments for increase (decrease) in trade, other payables and provisions to reconcile profit (loss) to net cash flow from (used in) operating activities.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_CashFlowsFromUsedInFinancingActivities" xml:lang="en">Net cash flows from (used in) financing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities" xlink:to="lab_ifrs-full_CashFlowsFromUsedInFinancingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xlink:label="loc_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xml:lang="en">Repayments of borrowings, classified as financing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xlink:to="lab_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_DividendsPaidClassifiedAsFinancingActivities" xlink:label="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" xml:lang="en">Dividends paid, classified as financing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" xlink:to="lab_ifrs-full_DividendsPaidClassifiedAsFinancingActivities" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xlink:label="loc_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xml:lang="en">Hedge Contracts Relating To Dividend Payments Receipts Classified As Financing Activities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xml:lang="en">Hedge Contracts Relating To Dividend Payments Receipts Classified As Financing Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xlink:to="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_HedgeContractsRelatingToDividendPaymentsReceiptsClassifiedAsFinancingActivities" xml:lang="en">The cash inflow or outflow from hedge contracts relating to dividend payments (receipts).</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xlink:label="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xml:lang="en">Payments of lease liabilities, classified as financing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xlink:to="lab_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_PaymentsToAcquireNonControllingInterests" xlink:label="loc_azn_PaymentsToAcquireNonControllingInterests" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_PaymentsToAcquireNonControllingInterests" xml:lang="en">Payments To Acquire Non Controlling Interests</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_PaymentsToAcquireNonControllingInterests" xml:lang="en">Payments To Acquire Non Controlling Interests</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_PaymentsToAcquireNonControllingInterests" xlink:to="lab_azn_PaymentsToAcquireNonControllingInterests" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_PaymentsToAcquireNonControllingInterests" xml:lang="en">Payments to acquire non-controlling interests.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_PaymentOfAcertaPharmaSharePurchaseLiability" xlink:label="loc_azn_PaymentOfAcertaPharmaSharePurchaseLiability" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_PaymentOfAcertaPharmaSharePurchaseLiability" xml:lang="en">Payment Of Acerta Pharma Share Purchase Liability</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_PaymentOfAcertaPharmaSharePurchaseLiability" xml:lang="en">Payment Of Acerta Pharma Share Purchase Liability</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_PaymentOfAcertaPharmaSharePurchaseLiability" xlink:to="lab_azn_PaymentOfAcertaPharmaSharePurchaseLiability" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_PaymentOfAcertaPharmaSharePurchaseLiability" xml:lang="en">Payment of acerta pharma share purchase liability.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xlink:label="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="lab_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xml:lang="en">Cash and cash equivalents at beginning of period</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="lab_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xml:lang="en">Cash and cash equivalents at end of period</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xlink:to="lab_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xml:lang="en">Purchase of property, plant and equipment, classified as investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xml:lang="en">Purchase of intangible assets, classified as investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" xml:lang="en">Purchase of other long-term assets, classified as investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xlink:label="loc_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xml:lang="en">Inflows Outflows Of Cash Related To Profit Participation Liability Classified As Investing Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xlink:to="lab_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_InflowsOutflowsOfCashRelatedToProfitParticipationLiabilityClassifiedAsInvestingActivities" xml:lang="en">Inflows (outflows) of cash related to profit participation liability, classified as investing activities.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" xml:lang="en">Cash flows used in obtaining control of subsidiaries or other businesses, classified as investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xlink:label="loc_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">Contingent Consideration Payment Business Combinations Classified As Investing Activities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">Contingent Consideration Payment Business Combinations Classified As Investing Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xlink:to="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_ContingentConsiderationPaymentBusinessCombinationsClassifiedAsInvestingActivities" xml:lang="en">The amount of contingent consideration paid on account of business combinations.</label>
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xlink:label="loc_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xml:lang="en">Payments Upon Vesting Of Employee Share Awards Attributable To Business Combinations</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xml:lang="en">Payments Upon Vesting Of Employee Share Awards Attributable To Business Combinations</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xlink:to="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_PaymentsUponVestingOfEmployeeShareAwardsAttributableToBusinessCombinations" xml:lang="en">Payments upon vesting of employee share awards attributable to business combinations.</label>
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_CashFlowsFromUsedInInvestingActivities" xml:lang="en">Net cash flows from (used in) investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities" xlink:to="lab_ifrs-full_CashFlowsFromUsedInInvestingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" xlink:label="loc_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="lab_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" xml:lang="en">Other cash payments to acquire interests in joint ventures, classified as investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" xlink:to="lab_ifrs-full_OtherCashPaymentsToAcquireInterestsInJointVenturesClassifiedAsInvestingActivities" />
    <loc xlink:type="locator" xlink:href="http://xbrl.ifrs.org/taxonomy/2021-03-24/full_ifrs/full_ifrs-cor_2021-03-24.xsd#ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges" xlink:label="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges" xml:lang="en">Net increase (decrease) in cash and cash equivalents</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges" xlink:to="lab_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges" />
    <loc xlink:type="locator" xlink:href="PY6ZZQWO2IZFZC3IOL08-2022-12-31.xsd#azn_CashFlowsFromUsedInOperatingAndInvestingActivities" xlink:label="loc_azn_CashFlowsFromUsedInOperatingAndInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_azn_CashFlowsFromUsedInOperatingAndInvestingActivities" xml:lang="en">Cash Flows From Used In Operating And Investing Activities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="lab_azn_CashFlowsFromUsedInOperatingAndInvestingActivities" xml:lang="en">Net cash inflow before financing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_azn_CashFlowsFromUsedInOperatingAndInvestingActivities" xlink:to="lab_azn_CashFlowsFromUsedInOperatingAndInvestingActivities" />
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="lab_azn_CashFlowsFromUsedInOperatingAndInvestingActivities" xml:lang="en">Net cash flows from (used in) operating and investing activities.</label>
  </labelLink>
</linkbase>