Research and development expense Repayments Of PGE Repayments Of PGE Repayments Of PGE Purchase of intangible assets, classified as investing activities Exercises Of Share Warrants Other Than through The Equity Line Agreement Exercises Of Share Warrants Other Than through The Equity Line Agreement Royalty certificates Royalty certificates Property plant and equipment including right-of-use assets Property plant and equipment including right-of-use assets Current portion of non current convertible loan notes Current portion of non current convertible loan notes Finance income (cost) Increase Decrease In Number Of Shares Issued Through Exercise Of Kreos Share Warrants Increase Decrease In Number Of Shares Issued Through Exercise Of Kreos Share Warrants Current receivables and current prepaid expenses Current receivables and current prepaid expenses Proceeds From Issuing Shares Other Than Through Exercise Of Warrants Proceeds From Issuing Shares Other Than Through Exercise Of Warrants Repayments of convertible loan notes Repayments of convertible loan notes Cash flows from (used in) operations before changes in working capital Adjustments For Unwinding Of Discount Related To Conditional Advances Adjustments For Unwinding Of Discount Related To Conditional Advances Operating expense Increase (decrease) in working capital Net Proceeds From The Royalty Certificates Net Proceeds From The Royalty Certificates Exercises Of Share Warrants KREOS Exercises Of Share Warrants KREOS Cash flows from (used in) operating activities Non current portion of non current loans received, excluding royalty certificates, bonds other than convertible notes and lease liabilities Non current portion of non current loans received, excluding royalty certificates, bonds other than convertible notes and lease liabilities Payments For Deposits Payments For Deposits Payments For Deposits Cash Advances And Loans Made To CRO Cash Advances And Loans Made To CRO Sales and marketing expense Increase Decrease In Number Of Shares Issued Through Exercise Of Share Warrants Other Than Kreos Increase Decrease In Number Of Shares Issued Through Exercise Of Share Warrants Other Than Kreos Cash flows from (used in) financing activities Interest paid, classified as financing activities Exercises Of Share Warrants Other Than Kreos Exercises Of Share Warrants Other Than Kreos Non current convertible loan notes Non current convertible loan notes Payments of lease liabilities, classified as financing activities Cash flows [Abstract] Current portion of non current loans received bonds other than convertible notes and lease liabilities Current portion of non current loans received bonds other than convertible notes and lease liabilities Exercises Of Share Warrants Under The Equity Line Agreement Exercises Of Share Warrants Under The Equity Line Agreement Increase Decrease In Number Of Shares Issued Through Exercise Of Share Warrants Increase Decrease In Number Of Shares Issued Through Exercise Of Share Warrants Repayments of KREOS bond loans Cash flows from (used in) investing activities Purchase of property, plant and equipment, classified as investing activities Increase Decrease In Number Of Ordinary Shares Issued Through Capital Increase Increase Decrease In Number Of Ordinary Shares Issued Through Capital Increase Increase (decrease) in cash and cash equivalents after effect of exchange rate changes Net proceeds from convertible loan notes Issue Of Equity Other Than Through Exercise Of Warrants Issue Of Equity Other Than Through Exercise Of Warrants General and administrative expense Increase Decrease In Number Of Shares Issued Through Exercise Of Share Warrants Under The Equity Line Agreement Increase Decrease In Number Of Shares Issued Through Exercise Of Share Warrants Under The Equity Line Agreement Number of shares issued Number of shares issued Revenue and other operating income Advances And Loans Made (Reimbursed) To (By) Hospitals Advances And Loans Made (Reimbursed) To (By) Hospitals Tax expense (income) Reimbursements Of Deposits Reimbursements Of Deposits Payments for share issue costs Purchase of other long-term assets, classified as investing activities Adjustments For Redemption Of Covid 19 Conditional Advances Adjustments For Redemption Of Covid 19 Conditional Advances Repayment Of Conditional Advances Repayment Of Conditional Advances Repayment Of Conditional Advances Adjustments For Net Gain On Sale Of Treasury Shares Adjustments For Net Gain On Sale Of Treasury Shares Profit (loss), attributable to owners of parent Issue of convertible notes Adjustments For Other Finance Income Adjustments For Other Finance Income Adjustments For Other Finance Income