<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2022 Workiva-->
<!--r:9dc768b3-0452-4810-9f36-5ffa16004403,g:86204787-e6a6-43b6-b7a9-1e0d54ea0e95-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://nanobiotix.com/role/StatementoffinancialpositioncurrentnoncurrentStatement" xlink:type="simple" xlink:href="nbx-2021-12-31.xsd#StatementoffinancialpositioncurrentnoncurrentStatement"/>
  <link:calculationLink xlink:role="http://nanobiotix.com/role/StatementoffinancialpositioncurrentnoncurrentStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentLiabilities_43c097eb-0dca-470b-92f5-1d387184e55c" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentFinancialLiabilities_e339674d-4845-4425-a5e4-2ac6e54ac457" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentFinancialLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentLiabilities_43c097eb-0dca-470b-92f5-1d387184e55c" xlink:to="loc_ifrs-full_NoncurrentFinancialLiabilities_e339674d-4845-4425-a5e4-2ac6e54ac457" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentProvisions_2199ec3d-6a74-47cb-9532-803593a66aef" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentProvisions"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentLiabilities_43c097eb-0dca-470b-92f5-1d387184e55c" xlink:to="loc_ifrs-full_NoncurrentProvisions_2199ec3d-6a74-47cb-9532-803593a66aef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentAssets_96133fb1-37ec-41a9-b503-2b2b7a5c2db3" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherCurrentAssets_ba3dcc76-07e6-4e5a-8fc3-20bd15540d9f" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherCurrentAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_96133fb1-37ec-41a9-b503-2b2b7a5c2db3" xlink:to="loc_ifrs-full_OtherCurrentAssets_ba3dcc76-07e6-4e5a-8fc3-20bd15540d9f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalents_24eb96b3-206f-4e0d-b979-843b3cdc6919" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashAndCashEquivalents"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_96133fb1-37ec-41a9-b503-2b2b7a5c2db3" xlink:to="loc_ifrs-full_CashAndCashEquivalents_24eb96b3-206f-4e0d-b979-843b3cdc6919" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentTradeReceivables_15df7244-64f2-45e0-bb90-41c66e5f6943" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentTradeReceivables"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_96133fb1-37ec-41a9-b503-2b2b7a5c2db3" xlink:to="loc_ifrs-full_CurrentTradeReceivables_15df7244-64f2-45e0-bb90-41c66e5f6943" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentLiabilities_81423f90-9502-490a-9c53-86eb65645aca" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherCurrentLiabilities_a807e9d9-b90f-44b4-b7a6-620f4cbb05a6" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherCurrentLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_81423f90-9502-490a-9c53-86eb65645aca" xlink:to="loc_ifrs-full_OtherCurrentLiabilities_a807e9d9-b90f-44b4-b7a6-620f4cbb05a6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentProvisions_e2e87932-0f92-47aa-b574-3adb979108d4" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentProvisions"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_81423f90-9502-490a-9c53-86eb65645aca" xlink:to="loc_ifrs-full_CurrentProvisions_e2e87932-0f92-47aa-b574-3adb979108d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentContractLiabilities_ad95b080-ce02-47eb-b3fc-6db1bc4e2095" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentContractLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_81423f90-9502-490a-9c53-86eb65645aca" xlink:to="loc_ifrs-full_CurrentContractLiabilities_ad95b080-ce02-47eb-b3fc-6db1bc4e2095" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentFinancialLiabilities_eade65f1-855f-4518-9059-050df0c71fd6" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentFinancialLiabilities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_81423f90-9502-490a-9c53-86eb65645aca" xlink:to="loc_ifrs-full_CurrentFinancialLiabilities_eade65f1-855f-4518-9059-050df0c71fd6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_TradeAndOtherCurrentPayables_f7431c65-c51b-425e-907a-d54df62ee171" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_TradeAndOtherCurrentPayables"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_81423f90-9502-490a-9c53-86eb65645aca" xlink:to="loc_ifrs-full_TradeAndOtherCurrentPayables_f7431c65-c51b-425e-907a-d54df62ee171" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_Equity"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_1e5aa81c-1fb8-4095-b934-82cc11aa67ba" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AccumulatedOtherComprehensiveIncome"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:to="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_1e5aa81c-1fb8-4095-b934-82cc11aa67ba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherReserves_018b6c2f-d76b-4c2d-be02-391ab44ac008" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherReserves"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:to="loc_ifrs-full_OtherReserves_018b6c2f-d76b-4c2d-be02-391ab44ac008" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_SharePremium_a298eefb-8962-4b76-bd47-917968f0da86" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_SharePremium"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:to="loc_ifrs-full_SharePremium_a298eefb-8962-4b76-bd47-917968f0da86" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IssuedCapital_642b4958-8bab-4118-93e5-6a4e265f5df1" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IssuedCapital"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:to="loc_ifrs-full_IssuedCapital_642b4958-8bab-4118-93e5-6a4e265f5df1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_nbx_NetLossForThePeriod_bdf64ace-e7ba-489a-8b30-9b15890f1f3b" xlink:href="nbx-2021-12-31.xsd#nbx_NetLossForThePeriod"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:to="loc_nbx_NetLossForThePeriod_bdf64ace-e7ba-489a-8b30-9b15890f1f3b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_TreasuryShares_208c9fcb-95bc-469b-b23d-49f6fb84ab00" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_TreasuryShares"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_dae581b6-ee92-43ff-a868-b44fe8f29fda" xlink:to="loc_ifrs-full_TreasuryShares_208c9fcb-95bc-469b-b23d-49f6fb84ab00" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EquityAndLiabilities_acd65ffb-2c05-44b8-bfc5-ff082e698107" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_EquityAndLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_6e566e6e-c895-4985-92f1-4ede01d0143a" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_Equity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_acd65ffb-2c05-44b8-bfc5-ff082e698107" xlink:to="loc_ifrs-full_Equity_6e566e6e-c895-4985-92f1-4ede01d0143a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentLiabilities_071c10ef-1b69-4e87-a906-7a3d33fc77cd" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_acd65ffb-2c05-44b8-bfc5-ff082e698107" xlink:to="loc_ifrs-full_NoncurrentLiabilities_071c10ef-1b69-4e87-a906-7a3d33fc77cd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentLiabilities_cee44d3b-68fd-4563-80e1-9b888a317ba3" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_acd65ffb-2c05-44b8-bfc5-ff082e698107" xlink:to="loc_ifrs-full_CurrentLiabilities_cee44d3b-68fd-4563-80e1-9b888a317ba3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Assets_00edfa81-697a-40f8-a4dd-d514b1f325b3" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentAssets_8db44861-b163-4bb0-a777-5d854d4ac1c0" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CurrentAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_00edfa81-697a-40f8-a4dd-d514b1f325b3" xlink:to="loc_ifrs-full_CurrentAssets_8db44861-b163-4bb0-a777-5d854d4ac1c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentAssets_d80af902-2e2b-41a0-9328-a2396a0c7e4b" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_00edfa81-697a-40f8-a4dd-d514b1f325b3" xlink:to="loc_ifrs-full_NoncurrentAssets_d80af902-2e2b-41a0-9328-a2396a0c7e4b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentAssets_d21a2aab-f6a4-4662-b9bc-4163b54f476c" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_e70b6c61-02c0-4805-b9e9-47622d5ca592" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_d21a2aab-f6a4-4662-b9bc-4163b54f476c" xlink:to="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_e70b6c61-02c0-4805-b9e9-47622d5ca592" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentFinancialAssets_951128ff-8e2e-4280-a7e2-aad1fcd55eca" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_NoncurrentFinancialAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_d21a2aab-f6a4-4662-b9bc-4163b54f476c" xlink:to="loc_ifrs-full_NoncurrentFinancialAssets_951128ff-8e2e-4280-a7e2-aad1fcd55eca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PropertyPlantAndEquipment_fdb977fa-c944-4b75-852b-3c0b11dd205c" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_PropertyPlantAndEquipment"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_d21a2aab-f6a4-4662-b9bc-4163b54f476c" xlink:to="loc_ifrs-full_PropertyPlantAndEquipment_fdb977fa-c944-4b75-852b-3c0b11dd205c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://nanobiotix.com/role/StatementofcomprehensiveincomeprofitorlossbyfunctionofexpenseStatement" xlink:type="simple" xlink:href="nbx-2021-12-31.xsd#StatementofcomprehensiveincomeprofitorlossbyfunctionofexpenseStatement"/>
  <link:calculationLink xlink:role="http://nanobiotix.com/role/StatementofcomprehensiveincomeprofitorlossbyfunctionofexpenseStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromOperatingActivities_10aabd74-03d8-492e-8cd3-ddbf05cb48cc" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProfitLossFromOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Revenue_5a473790-f6dd-481f-b0a3-cfca94015b86" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_Revenue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromOperatingActivities_10aabd74-03d8-492e-8cd3-ddbf05cb48cc" xlink:to="loc_ifrs-full_Revenue_5a473790-f6dd-481f-b0a3-cfca94015b86" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OperatingExpense_a9b4e0f7-6385-4be4-8e99-48d3f8f02b63" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OperatingExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromOperatingActivities_10aabd74-03d8-492e-8cd3-ddbf05cb48cc" xlink:to="loc_ifrs-full_OperatingExpense_a9b4e0f7-6385-4be4-8e99-48d3f8f02b63" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceIncomeCost_b01f80c7-beeb-4f32-8ff3-a051aa15fb1a" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_FinanceIncomeCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceCosts_8b594fd8-73b2-4f91-90a3-402649219158" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_FinanceCosts"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_FinanceIncomeCost_b01f80c7-beeb-4f32-8ff3-a051aa15fb1a" xlink:to="loc_ifrs-full_FinanceCosts_8b594fd8-73b2-4f91-90a3-402649219158" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceIncome_900d1054-f802-42c1-aa76-0948db15b4a4" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_FinanceIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_FinanceIncomeCost_b01f80c7-beeb-4f32-8ff3-a051aa15fb1a" xlink:to="loc_ifrs-full_FinanceIncome_900d1054-f802-42c1-aa76-0948db15b4a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_b01cdae7-098a-4265-9680-802c6d02e98c" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProfitLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromOperatingActivities_75136e17-e6ce-4418-9efb-917d8cb42f1b" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProfitLossFromOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_b01cdae7-098a-4265-9680-802c6d02e98c" xlink:to="loc_ifrs-full_ProfitLossFromOperatingActivities_75136e17-e6ce-4418-9efb-917d8cb42f1b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceIncomeCost_ee5d0c40-fd0d-4b12-aecd-5adb8fe602e0" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_FinanceIncomeCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_b01cdae7-098a-4265-9680-802c6d02e98c" xlink:to="loc_ifrs-full_FinanceIncomeCost_ee5d0c40-fd0d-4b12-aecd-5adb8fe602e0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxExpenseContinuingOperations_ce0dd292-e34f-4478-b639-90cf1fed38fa" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IncomeTaxExpenseContinuingOperations"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_b01cdae7-098a-4265-9680-802c6d02e98c" xlink:to="loc_ifrs-full_IncomeTaxExpenseContinuingOperations_ce0dd292-e34f-4478-b639-90cf1fed38fa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Revenue_3fe8cf9c-2151-4992-9645-1de48bc593fa" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_Revenue"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevenueFromContractsWithCustomers_af9dd0db-faf0-4851-a414-c55a13d73799" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_RevenueFromContractsWithCustomers"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Revenue_3fe8cf9c-2151-4992-9645-1de48bc593fa" xlink:to="loc_ifrs-full_RevenueFromContractsWithCustomers_af9dd0db-faf0-4851-a414-c55a13d73799" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherIncome_ff4a5b32-1cf3-4b48-8ff5-de73450a46f4" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Revenue_3fe8cf9c-2151-4992-9645-1de48bc593fa" xlink:to="loc_ifrs-full_OtherIncome_ff4a5b32-1cf3-4b48-8ff5-de73450a46f4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OperatingExpense_913ed0e7-f7f2-4f5b-9c17-3ee158c851d3" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OperatingExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherOperatingIncomeExpense_b1b4e84b-18d1-4c93-88ec-808de1802d4a" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherOperatingIncomeExpense"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OperatingExpense_913ed0e7-f7f2-4f5b-9c17-3ee158c851d3" xlink:to="loc_ifrs-full_OtherOperatingIncomeExpense_b1b4e84b-18d1-4c93-88ec-808de1802d4a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ResearchAndDevelopmentExpense_702052fd-c3d6-4db5-9e13-2aba7da9f7cb" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OperatingExpense_913ed0e7-f7f2-4f5b-9c17-3ee158c851d3" xlink:to="loc_ifrs-full_ResearchAndDevelopmentExpense_702052fd-c3d6-4db5-9e13-2aba7da9f7cb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_SellingGeneralAndAdministrativeExpense_1f200163-b7f7-41e5-945a-0275e2d2da09" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OperatingExpense_913ed0e7-f7f2-4f5b-9c17-3ee158c851d3" xlink:to="loc_ifrs-full_SellingGeneralAndAdministrativeExpense_1f200163-b7f7-41e5-945a-0275e2d2da09" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://nanobiotix.com/role/StatementofcomprehensiveincomeOCIcomponentspresentednetoftaxStatement" xlink:type="simple" xlink:href="nbx-2021-12-31.xsd#StatementofcomprehensiveincomeOCIcomponentspresentednetoftaxStatement"/>
  <link:calculationLink xlink:role="http://nanobiotix.com/role/StatementofcomprehensiveincomeOCIcomponentspresentednetoftaxStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncome_41d50e38-1f27-4836-9cd3-739e35eaa53f" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_dbc0f013-ee41-4fe3-bb33-5059378a1a80" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_41d50e38-1f27-4836-9cd3-739e35eaa53f" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_dbc0f013-ee41-4fe3-bb33-5059378a1a80" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_87c0a5b9-690e-4d70-89a4-57fc882d0783" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProfitLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_41d50e38-1f27-4836-9cd3-739e35eaa53f" xlink:to="loc_ifrs-full_ProfitLoss_87c0a5b9-690e-4d70-89a4-57fc882d0783" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_dac12c65-6481-4825-955b-90cebe25f35a" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_41d50e38-1f27-4836-9cd3-739e35eaa53f" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_dac12c65-6481-4825-955b-90cebe25f35a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_ee0eddae-be4d-44c3-8fb9-1f87e0be2321" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationBeforeTax_3b49ecf6-9492-4db6-95df-f40b3b51d3b3" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_ee0eddae-be4d-44c3-8fb9-1f87e0be2321" xlink:to="loc_ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationBeforeTax_3b49ecf6-9492-4db6-95df-f40b3b51d3b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxRelatingToExchangeDifferencesOnTranslationOfOtherComprehensiveIncome_7e728a24-30dd-4451-abe4-632428dccbf1" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IncomeTaxRelatingToExchangeDifferencesOnTranslationOfOtherComprehensiveIncome"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_ee0eddae-be4d-44c3-8fb9-1f87e0be2321" xlink:to="loc_ifrs-full_IncomeTaxRelatingToExchangeDifferencesOnTranslationOfOtherComprehensiveIncome_7e728a24-30dd-4451-abe4-632428dccbf1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_d9fc3f78-a22a-417d-b135-ae300b8870dd" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxRelatingToRemeasurementsOfDefinedBenefitPlansOfOtherComprehensiveIncome_acd2eb7d-aef4-4f1e-8b2e-15eb8337f81a" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IncomeTaxRelatingToRemeasurementsOfDefinedBenefitPlansOfOtherComprehensiveIncome"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_d9fc3f78-a22a-417d-b135-ae300b8870dd" xlink:to="loc_ifrs-full_IncomeTaxRelatingToRemeasurementsOfDefinedBenefitPlansOfOtherComprehensiveIncome_acd2eb7d-aef4-4f1e-8b2e-15eb8337f81a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_ed1f8165-e1d7-4909-9d1a-18aa9f9b9eff" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_d9fc3f78-a22a-417d-b135-ae300b8870dd" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_ed1f8165-e1d7-4909-9d1a-18aa9f9b9eff" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://nanobiotix.com/role/StatementofchangesinequityStatement" xlink:type="simple" xlink:href="nbx-2021-12-31.xsd#StatementofchangesinequityStatement"/>
  <link:calculationLink xlink:role="http://nanobiotix.com/role/StatementofchangesinequityStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncome_91771149-a345-4fb6-9d17-fc3bdd449728" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_31000f55-1ec9-47cf-8cfc-2f85397486cf" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProfitLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_91771149-a345-4fb6-9d17-fc3bdd449728" xlink:to="loc_ifrs-full_ProfitLoss_31000f55-1ec9-47cf-8cfc-2f85397486cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation_24b8bc9f-e516-4b74-ba90-bcb401cc6a01" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_91771149-a345-4fb6-9d17-fc3bdd449728" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation_24b8bc9f-e516-4b74-ba90-bcb401cc6a01" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_a09b0c0a-c6f3-46dd-bacb-6200c4869eaf" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_91771149-a345-4fb6-9d17-fc3bdd449728" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_a09b0c0a-c6f3-46dd-bacb-6200c4869eaf" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://nanobiotix.com/role/StatementofcashflowsindirectmethodStatement" xlink:type="simple" xlink:href="nbx-2021-12-31.xsd#StatementofcashflowsindirectmethodStatement"/>
  <link:calculationLink xlink:role="http://nanobiotix.com/role/StatementofcashflowsindirectmethodStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_6caa6e38-304a-4f64-8d57-6666cfc3d748" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities_70c45890-0693-40fa-965b-9a8593ef7647" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_6caa6e38-304a-4f64-8d57-6666cfc3d748" xlink:to="loc_ifrs-full_PurchaseOfOtherLongtermAssetsClassifiedAsInvestingActivities_70c45890-0693-40fa-965b-9a8593ef7647" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_80c5b985-7ef7-47bf-bb22-869e614527b4" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_6caa6e38-304a-4f64-8d57-6666cfc3d748" xlink:to="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_80c5b985-7ef7-47bf-bb22-869e614527b4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities_3705e5e1-04ec-45d5-9e7f-f71731a890dd" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_6caa6e38-304a-4f64-8d57-6666cfc3d748" xlink:to="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities_3705e5e1-04ec-45d5-9e7f-f71731a890dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IncreaseDecreaseInWorkingCapital"/>
    <link:loc xlink:type="locator" xlink:label="loc_nbx_AdjustmentsForDecreaseIncreaseInOtherReceivables_52c187e8-a115-4b8f-811c-5da5a7eea422" xlink:href="nbx-2021-12-31.xsd#nbx_AdjustmentsForDecreaseIncreaseInOtherReceivables"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:to="loc_nbx_AdjustmentsForDecreaseIncreaseInOtherReceivables_52c187e8-a115-4b8f-811c-5da5a7eea422" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInOtherCurrentLiabilities_dc32e988-8a7a-40e0-b455-0558d2aaf454" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInOtherCurrentLiabilities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInOtherCurrentLiabilities_dc32e988-8a7a-40e0-b455-0558d2aaf454" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables_f011a149-7217-4fb9-a323-fd63ab4ac8e4" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables_f011a149-7217-4fb9-a323-fd63ab4ac8e4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_nbx_AdjustmentForIncreaseDecreaseInDeferredIncomeAndContractLiabilities_e593f506-9a7e-4703-b61a-3a79a1ec490c" xlink:href="nbx-2021-12-31.xsd#nbx_AdjustmentForIncreaseDecreaseInDeferredIncomeAndContractLiabilities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:to="loc_nbx_AdjustmentForIncreaseDecreaseInDeferredIncomeAndContractLiabilities_e593f506-9a7e-4703-b61a-3a79a1ec490c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_nbx_AdjustmentsForDecreaseIncreaseInReceivablesFromTaxesOtherThanIncomeTax_3abe4cd3-6097-4d37-8ca4-44863888e388" xlink:href="nbx-2021-12-31.xsd#nbx_AdjustmentsForDecreaseIncreaseInReceivablesFromTaxesOtherThanIncomeTax"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:to="loc_nbx_AdjustmentsForDecreaseIncreaseInReceivablesFromTaxesOtherThanIncomeTax_3abe4cd3-6097-4d37-8ca4-44863888e388" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAccountReceivable_5527371d-358c-40a1-9970-ebaa3885c143" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAccountReceivable"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_7a6c5cdd-7c22-4dbe-b4fd-7c4fdf67f538" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAccountReceivable_5527371d-358c-40a1-9970-ebaa3885c143" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAdjustmentsForNoncashItems_fbc5ca5d-3274-4439-a278-ae014384f805" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_OtherAdjustmentsForNoncashItems"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_OtherAdjustmentsForNoncashItems_fbc5ca5d-3274-4439-a278-ae014384f805" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForSharebasedPayments_7097ac59-7581-4067-95d2-0d998f462de0" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForSharebasedPayments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_AdjustmentsForSharebasedPayments_7097ac59-7581-4067-95d2-0d998f462de0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForFinanceCosts_37270eba-9767-4c26-83d6-47dc6b959502" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForFinanceCosts"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_AdjustmentsForFinanceCosts_37270eba-9767-4c26-83d6-47dc6b959502" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_a92408c4-1bcd-4f1e-832f-71c6cda28951" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProfitLoss"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_ProfitLoss_a92408c4-1bcd-4f1e-832f-71c6cda28951" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInDerivativeFinancialLiabilities_44efd91e-439c-45d8-964d-6460bb9cf493" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInDerivativeFinancialLiabilities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInDerivativeFinancialLiabilities_44efd91e-439c-45d8-964d-6460bb9cf493" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForProvisions_9b8fc1f0-ea52-460c-9455-9b5348182844" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForProvisions"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_AdjustmentsForProvisions_9b8fc1f0-ea52-460c-9455-9b5348182844" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_350a4fa4-0164-4067-86bd-56455294f2eb" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_82e6775b-27ad-41cf-8599-0d4cca96cd58" xlink:to="loc_ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_350a4fa4-0164-4067-86bd-56455294f2eb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_3ce0ceb3-867e-4ca4-b54d-731bd2a0d79b" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IncreaseDecreaseInCashAndCashEquivalents"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_285509b8-3f88-490f-b136-d5e9706846ad" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_3ce0ceb3-867e-4ca4-b54d-731bd2a0d79b" xlink:to="loc_ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_285509b8-3f88-490f-b136-d5e9706846ad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_ee5a0f2f-d976-4533-87d3-9f4b9ae7109e" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_3ce0ceb3-867e-4ca4-b54d-731bd2a0d79b" xlink:to="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_ee5a0f2f-d976-4533-87d3-9f4b9ae7109e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_1d111121-5e3c-4919-bb3c-5c867cd0a36c" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_3ce0ceb3-867e-4ca4-b54d-731bd2a0d79b" xlink:to="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_1d111121-5e3c-4919-bb3c-5c867cd0a36c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_431e5c26-c731-4010-ac7b-b7d9373b158d" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_3ce0ceb3-867e-4ca4-b54d-731bd2a0d79b" xlink:to="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_431e5c26-c731-4010-ac7b-b7d9373b158d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PaymentsForShareIssueCosts_ab414510-6982-4e45-b27a-2210917ecae2" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_PaymentsForShareIssueCosts"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_ifrs-full_PaymentsForShareIssueCosts_ab414510-6982-4e45-b27a-2210917ecae2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities_7cd0ec0a-cd2e-42d8-b5ec-9fa6b1892705" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities_7cd0ec0a-cd2e-42d8-b5ec-9fa6b1892705" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities_f168343e-b5b9-49c9-97ec-b02435813538" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities_f168343e-b5b9-49c9-97ec-b02435813538" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestPaidClassifiedAsFinancingActivities_11d2753a-b37a-4a12-94e5-4a9eb7569616" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_InterestPaidClassifiedAsFinancingActivities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_ifrs-full_InterestPaidClassifiedAsFinancingActivities_11d2753a-b37a-4a12-94e5-4a9eb7569616" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromIssueOfOrdinaryShares_03bd031b-e068-46af-a002-a43fb2db6303" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_ProceedsFromIssueOfOrdinaryShares"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_ifrs-full_ProceedsFromIssueOfOrdinaryShares_03bd031b-e068-46af-a002-a43fb2db6303" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_4f78036e-85d6-4d56-9109-d7a5568542a9" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_4f78036e-85d6-4d56-9109-d7a5568542a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_nbx_ProceedsFromWarrantsSubscription_abaddd2c-83fe-4991-9880-9edddd6f47e8" xlink:href="nbx-2021-12-31.xsd#nbx_ProceedsFromWarrantsSubscription"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_nbx_ProceedsFromWarrantsSubscription_abaddd2c-83fe-4991-9880-9edddd6f47e8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_nbx_LeaseDebtInterestPaidClassifiedAsFinancingActivities_9f3233e8-8392-45e7-9dbe-95781d9431e7" xlink:href="nbx-2021-12-31.xsd#nbx_LeaseDebtInterestPaidClassifiedAsFinancingActivities"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_2e29b68d-6d16-4dd4-9e6c-f939bcebb8f0" xlink:to="loc_nbx_LeaseDebtInterestPaidClassifiedAsFinancingActivities_9f3233e8-8392-45e7-9dbe-95781d9431e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_68428efe-63fe-455d-a9d3-20d2f4fa27a7" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_132ead03-cfb1-4504-a171-8a1d755e14ae" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_68428efe-63fe-455d-a9d3-20d2f4fa27a7" xlink:to="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_132ead03-cfb1-4504-a171-8a1d755e14ae" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_ff0e62f9-d5b1-4a59-b3e8-ddec40a95902" xlink:href="http://xbrl.ifrs.org/taxonomy/2020-03-16/full_ifrs/full_ifrs-cor_2020-03-16.xsd#ifrs-full_IncreaseDecreaseInWorkingCapital"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_68428efe-63fe-455d-a9d3-20d2f4fa27a7" xlink:to="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_ff0e62f9-d5b1-4a59-b3e8-ddec40a95902" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
