<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2024 Workiva-->
<!--r:fff40a89-cd19-49e5-b5e0-f6dec33e60f4,g:6bb07bd2-cdf5-498f-879b-32cf98227fb8-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.pharming.com/role/StatementofcomprehensiveincomeprofitorlossbyfunctionofexpenseStatement" xlink:type="simple" xlink:href="pharm-2023-12-31.xsd#StatementofcomprehensiveincomeprofitorlossbyfunctionofexpenseStatement"/>
  <link:calculationLink xlink:role="http://www.pharming.com/role/StatementofcomprehensiveincomeprofitorlossbyfunctionofexpenseStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GrossProfit_3ba9290f-1849-466b-bc82-5643523fd933" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Revenue_ac78c278-904d-412b-bd22-05bab9cbf46c" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Revenue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_3ba9290f-1849-466b-bc82-5643523fd933" xlink:to="loc_ifrs-full_Revenue_ac78c278-904d-412b-bd22-05bab9cbf46c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CostOfSales_46ed8d6e-f6ce-400f-a0f7-306fcfa734bf" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CostOfSales"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_3ba9290f-1849-466b-bc82-5643523fd933" xlink:to="loc_ifrs-full_CostOfSales_46ed8d6e-f6ce-400f-a0f7-306fcfa734bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceIncomeCost_5e12334c-4240-43db-9574-bd11a6ff1dff" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_FinanceIncomeCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceIncome_6016277a-48a7-4115-ba3a-012c2aeb173e" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_FinanceIncome"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_FinanceIncomeCost_5e12334c-4240-43db-9574-bd11a6ff1dff" xlink:to="loc_ifrs-full_FinanceIncome_6016277a-48a7-4115-ba3a-012c2aeb173e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceCosts_c91896ea-2446-45ef-920e-167a48c16261" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_FinanceCosts"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_FinanceIncomeCost_5e12334c-4240-43db-9574-bd11a6ff1dff" xlink:to="loc_ifrs-full_FinanceCosts_c91896ea-2446-45ef-920e-167a48c16261" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnFinancialAssetsAtFairValueThroughProfitOrLoss_70915978-cee3-4295-89cd-692a977d9f3b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_GainsLossesOnFinancialAssetsAtFairValueThroughProfitOrLoss"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_FinanceIncomeCost_5e12334c-4240-43db-9574-bd11a6ff1dff" xlink:to="loc_ifrs-full_GainsLossesOnFinancialAssetsAtFairValueThroughProfitOrLoss_70915978-cee3-4295-89cd-692a977d9f3b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_83505bb7-8847-495a-9182-8cf024854bd9" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxExpenseContinuingOperations_b96b9224-6b94-4284-84de-ea133e00d37f" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncomeTaxExpenseContinuingOperations"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_83505bb7-8847-495a-9182-8cf024854bd9" xlink:to="loc_ifrs-full_IncomeTaxExpenseContinuingOperations_b96b9224-6b94-4284-84de-ea133e00d37f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_045ac5f3-d9c7-4523-a2cc-5d9fea5843f5" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_83505bb7-8847-495a-9182-8cf024854bd9" xlink:to="loc_ifrs-full_ProfitLossBeforeTax_045ac5f3-d9c7-4523-a2cc-5d9fea5843f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_186ab8aa-2ef8-49cf-b713-28ed264d5bbc" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ShareOfProfitLossOfAssociatesAccountedForUsingEquityMethod_db0fbe31-b6c0-4aa9-a050-46799b6c5009" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ShareOfProfitLossOfAssociatesAccountedForUsingEquityMethod"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_186ab8aa-2ef8-49cf-b713-28ed264d5bbc" xlink:to="loc_ifrs-full_ShareOfProfitLossOfAssociatesAccountedForUsingEquityMethod_db0fbe31-b6c0-4aa9-a050-46799b6c5009" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinanceIncomeCost_5998a9f8-e598-40c9-b027-e4b2acf77d1d" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_FinanceIncomeCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_186ab8aa-2ef8-49cf-b713-28ed264d5bbc" xlink:to="loc_ifrs-full_FinanceIncomeCost_5998a9f8-e598-40c9-b027-e4b2acf77d1d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromOperatingActivities_71e97e4a-ee6a-4115-a35d-3ec3cb32f1b6" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossFromOperatingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_186ab8aa-2ef8-49cf-b713-28ed264d5bbc" xlink:to="loc_ifrs-full_ProfitLossFromOperatingActivities_71e97e4a-ee6a-4115-a35d-3ec3cb32f1b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherExpenseByFunction_6a363646-5800-4fa0-9838-b905119bffb1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherExpenseByFunction"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_SalesAndMarketingExpense_73b0533b-910f-490b-b4ae-8f2f1e31e6a4" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_SalesAndMarketingExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherExpenseByFunction_6a363646-5800-4fa0-9838-b905119bffb1" xlink:to="loc_ifrs-full_SalesAndMarketingExpense_73b0533b-910f-490b-b4ae-8f2f1e31e6a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdministrativeExpense_9746d1ba-2c94-4a62-9afe-3026d39cb494" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdministrativeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherExpenseByFunction_6a363646-5800-4fa0-9838-b905119bffb1" xlink:to="loc_ifrs-full_AdministrativeExpense_9746d1ba-2c94-4a62-9afe-3026d39cb494" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ResearchAndDevelopmentExpense_32dc4a21-3e19-46a9-831e-1e862979e9f3" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherExpenseByFunction_6a363646-5800-4fa0-9838-b905119bffb1" xlink:to="loc_ifrs-full_ResearchAndDevelopmentExpense_32dc4a21-3e19-46a9-831e-1e862979e9f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromOperatingActivities_7c23d2eb-1a6d-4ab8-8d50-5abf87776324" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossFromOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherIncome_07d9be3e-0ef1-4496-bdc8-67946b62877f" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherIncome"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromOperatingActivities_7c23d2eb-1a6d-4ab8-8d50-5abf87776324" xlink:to="loc_ifrs-full_OtherIncome_07d9be3e-0ef1-4496-bdc8-67946b62877f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GrossProfit_1265d31e-a0fd-4859-9170-8058b0d81dc3" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_GrossProfit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromOperatingActivities_7c23d2eb-1a6d-4ab8-8d50-5abf87776324" xlink:to="loc_ifrs-full_GrossProfit_1265d31e-a0fd-4859-9170-8058b0d81dc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherExpenseByFunction_a9cd1129-eca1-41b5-84e8-0647a66d18d6" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherExpenseByFunction"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromOperatingActivities_7c23d2eb-1a6d-4ab8-8d50-5abf87776324" xlink:to="loc_ifrs-full_OtherExpenseByFunction_a9cd1129-eca1-41b5-84e8-0647a66d18d6" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.pharming.com/role/StatementofcomprehensiveincomeOCIcomponentspresentednetoftaxStatement" xlink:type="simple" xlink:href="pharm-2023-12-31.xsd#StatementofcomprehensiveincomeOCIcomponentspresentednetoftaxStatement"/>
  <link:calculationLink xlink:role="http://www.pharming.com/role/StatementofcomprehensiveincomeOCIcomponentspresentednetoftaxStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncome_d52eb7ff-37fd-485e-bbe6-7a4282d3d01b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_546bfbbb-3606-4c00-9976-1545d95a8366" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncome_d52eb7ff-37fd-485e-bbe6-7a4282d3d01b" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_546bfbbb-3606-4c00-9976-1545d95a8366" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_54b3e838-bd40-442e-95e4-7e31f1033866" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncome_d52eb7ff-37fd-485e-bbe6-7a4282d3d01b" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_54b3e838-bd40-442e-95e4-7e31f1033866" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_d4f7ee07-79c6-4719-ab59-86a9da6d3631" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesFromInvestmentsInEquityInstruments_4bd54c39-9090-4e89-8413-5b6ecd8ecd25" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesFromInvestmentsInEquityInstruments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_d4f7ee07-79c6-4719-ab59-86a9da6d3631" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesFromInvestmentsInEquityInstruments_4bd54c39-9090-4e89-8413-5b6ecd8ecd25" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_3ab22754-c7b8-489f-b229-8d56d3501fd2" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation_7e2505c2-2f03-4bfa-b9c1-18d6bb5d94c3" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_3ab22754-c7b8-489f-b229-8d56d3501fd2" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation_7e2505c2-2f03-4bfa-b9c1-18d6bb5d94c3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncome_74f37370-3b74-4617-b504-df552c66196c" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_4a8146e6-ae3d-420f-a14a-d21de1e58d88" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_74f37370-3b74-4617-b504-df552c66196c" xlink:to="loc_ifrs-full_ProfitLoss_4a8146e6-ae3d-420f-a14a-d21de1e58d88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncome_51a048f3-52f8-4739-9a4c-3735866ab061" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_74f37370-3b74-4617-b504-df552c66196c" xlink:to="loc_ifrs-full_OtherComprehensiveIncome_51a048f3-52f8-4739-9a4c-3735866ab061" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.pharming.com/role/StatementoffinancialpositioncurrentnoncurrentStatement" xlink:type="simple" xlink:href="pharm-2023-12-31.xsd#StatementoffinancialpositioncurrentnoncurrentStatement"/>
  <link:calculationLink xlink:role="http://www.pharming.com/role/StatementoffinancialpositioncurrentnoncurrentStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EquityAndLiabilities_47bbf15f-ccd1-4e9e-969c-986e82cd9e3d" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityAndLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_81c0d020-5781-4077-9625-e3466ae50a04" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Equity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_47bbf15f-ccd1-4e9e-969c-986e82cd9e3d" xlink:to="loc_ifrs-full_Equity_81c0d020-5781-4077-9625-e3466ae50a04" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentLiabilities_854ca1de-a6be-46d5-9ec2-fd9c8a19644a" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_47bbf15f-ccd1-4e9e-969c-986e82cd9e3d" xlink:to="loc_ifrs-full_CurrentLiabilities_854ca1de-a6be-46d5-9ec2-fd9c8a19644a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentLiabilities_ca1e1c60-1784-4264-aa50-d107cd62dc69" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_47bbf15f-ccd1-4e9e-969c-986e82cd9e3d" xlink:to="loc_ifrs-full_NoncurrentLiabilities_ca1e1c60-1784-4264-aa50-d107cd62dc69" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentLiabilities_5b74daac-9890-40da-a444-6d5986ab88ae" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_TradeAndOtherCurrentPayables_2993530e-5b1b-4beb-a2bd-37010a6e9978" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TradeAndOtherCurrentPayables"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_5b74daac-9890-40da-a444-6d5986ab88ae" xlink:to="loc_ifrs-full_TradeAndOtherCurrentPayables_2993530e-5b1b-4beb-a2bd-37010a6e9978" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentBondsIssuedAndCurrentPortionOfNoncurrentBondsIssued_bc94e6ea-71ce-4c20-9376-55a9e650b3a0" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentBondsIssuedAndCurrentPortionOfNoncurrentBondsIssued"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_5b74daac-9890-40da-a444-6d5986ab88ae" xlink:to="loc_ifrs-full_CurrentBondsIssuedAndCurrentPortionOfNoncurrentBondsIssued_bc94e6ea-71ce-4c20-9376-55a9e650b3a0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentLeaseLiabilities_07135136-7908-4c72-b866-7a0621e0e650" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentLeaseLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentLiabilities_5b74daac-9890-40da-a444-6d5986ab88ae" xlink:to="loc_ifrs-full_CurrentLeaseLiabilities_07135136-7908-4c72-b866-7a0621e0e650" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_77284ad9-854e-41a3-be00-b5b545cdb764" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Equity"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherReserves_e842b99b-0762-4fb1-8512-f7b671afce71" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherReserves"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_77284ad9-854e-41a3-be00-b5b545cdb764" xlink:to="loc_ifrs-full_OtherReserves_e842b99b-0762-4fb1-8512-f7b671afce71" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_SharePremium_c4dc4f97-3d28-4518-8ec9-8db416544681" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_SharePremium"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_77284ad9-854e-41a3-be00-b5b545cdb764" xlink:to="loc_ifrs-full_SharePremium_c4dc4f97-3d28-4518-8ec9-8db416544681" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RetainedEarnings_c887358f-30da-412f-bbd1-be32d93d4ebc" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RetainedEarnings"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_77284ad9-854e-41a3-be00-b5b545cdb764" xlink:to="loc_ifrs-full_RetainedEarnings_c887358f-30da-412f-bbd1-be32d93d4ebc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IssuedCapital_0eb63df9-0238-4796-80b8-9a9b8fc1b876" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IssuedCapital"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_77284ad9-854e-41a3-be00-b5b545cdb764" xlink:to="loc_ifrs-full_IssuedCapital_0eb63df9-0238-4796-80b8-9a9b8fc1b876" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_28d56f72-b437-459b-a592-83b11f2b8a3b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_28d56f72-b437-459b-a592-83b11f2b8a3b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RightofuseAssets_ea36e1e4-17ff-4b71-9acd-97cddfb98718" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RightofuseAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_RightofuseAssets_ea36e1e4-17ff-4b71-9acd-97cddfb98718" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentRestrictedCashAndCashEquivalents_1fb74db7-d422-4eb9-8526-f656f5a7225b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentRestrictedCashAndCashEquivalents"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_NoncurrentRestrictedCashAndCashEquivalents_1fb74db7-d422-4eb9-8526-f656f5a7225b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_173f43a7-6b9d-4922-9819-8b8aef14c5d1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_InvestmentAccountedForUsingEquityMethod"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_173f43a7-6b9d-4922-9819-8b8aef14c5d1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DeferredTaxAssets_7818c439-0d36-40f0-8c74-0d115fc3f065" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DeferredTaxAssets"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_DeferredTaxAssets_7818c439-0d36-40f0-8c74-0d115fc3f065" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentInvestmentsInEquityInstrumentsDesignatedAtFairValueThroughOtherComprehensiveIncome_dcbf45b6-e181-4c56-af9d-65cedc46841e" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentInvestmentsInEquityInstrumentsDesignatedAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_NoncurrentInvestmentsInEquityInstrumentsDesignatedAtFairValueThroughOtherComprehensiveIncome_dcbf45b6-e181-4c56-af9d-65cedc46841e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PropertyPlantAndEquipment_85d9b0ca-8822-49cf-8b66-5d610207299b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PropertyPlantAndEquipment"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_PropertyPlantAndEquipment_85d9b0ca-8822-49cf-8b66-5d610207299b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentPrepayments_ddee09ec-cb7e-4d2e-b237-f0ba36ecf55b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentPrepayments"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_NoncurrentPrepayments_ddee09ec-cb7e-4d2e-b237-f0ba36ecf55b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss_3d5101fb-9e8b-445f-9943-e5cd0f0cee2f" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentAssets_8d020a11-4aaa-4f76-a1b5-094f46af43e5" xlink:to="loc_ifrs-full_NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss_3d5101fb-9e8b-445f-9943-e5cd0f0cee2f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentLiabilities_c2e7a180-464a-40d9-8a85-207e3d93e73a" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentPortionOfNoncurrentBondsIssued_5c742d2c-9fb8-44e6-a3b5-4bd486a53dff" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentPortionOfNoncurrentBondsIssued"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentLiabilities_c2e7a180-464a-40d9-8a85-207e3d93e73a" xlink:to="loc_ifrs-full_NoncurrentPortionOfNoncurrentBondsIssued_5c742d2c-9fb8-44e6-a3b5-4bd486a53dff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentLeaseLiabilities_d1e04b5e-983c-492c-b822-bd606419b21c" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentLeaseLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncurrentLiabilities_c2e7a180-464a-40d9-8a85-207e3d93e73a" xlink:to="loc_ifrs-full_NoncurrentLeaseLiabilities_d1e04b5e-983c-492c-b822-bd606419b21c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentAssets_e7834cf4-1879-460a-9b09-8bd5da0768b1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalents_8956eab3-f1f4-4ae7-95d6-67e414fe9e21" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashAndCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_e7834cf4-1879-460a-9b09-8bd5da0768b1" xlink:to="loc_ifrs-full_CashAndCashEquivalents_8956eab3-f1f4-4ae7-95d6-67e414fe9e21" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_TradeAndOtherCurrentReceivables_92c0930e-d388-4aff-a55a-224139d5f732" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TradeAndOtherCurrentReceivables"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_e7834cf4-1879-460a-9b09-8bd5da0768b1" xlink:to="loc_ifrs-full_TradeAndOtherCurrentReceivables_92c0930e-d388-4aff-a55a-224139d5f732" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Inventories_a865e383-818d-4b6f-bd57-036d294a2538" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Inventories"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_e7834cf4-1879-460a-9b09-8bd5da0768b1" xlink:to="loc_ifrs-full_Inventories_a865e383-818d-4b6f-bd57-036d294a2538" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentRestrictedCashAndCashEquivalents_af07eb10-286f-4878-8e4b-58c61f62dca7" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentRestrictedCashAndCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_e7834cf4-1879-460a-9b09-8bd5da0768b1" xlink:to="loc_ifrs-full_CurrentRestrictedCashAndCashEquivalents_af07eb10-286f-4878-8e4b-58c61f62dca7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_pharm_MarketableSecurities_9d583983-90e8-4a6f-95f3-a8b5e203badb" xlink:href="pharm-2023-12-31.xsd#pharm_MarketableSecurities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CurrentAssets_e7834cf4-1879-460a-9b09-8bd5da0768b1" xlink:to="loc_pharm_MarketableSecurities_9d583983-90e8-4a6f-95f3-a8b5e203badb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Assets_340de91d-76be-420d-a9e1-5ae49e04748f" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentAssets_5794f3da-5a62-47b7-99dd-16be7182a47b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_340de91d-76be-420d-a9e1-5ae49e04748f" xlink:to="loc_ifrs-full_NoncurrentAssets_5794f3da-5a62-47b7-99dd-16be7182a47b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentAssets_8810bd59-9a09-49bf-a6ce-e49f3aaaebe4" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_340de91d-76be-420d-a9e1-5ae49e04748f" xlink:to="loc_ifrs-full_CurrentAssets_8810bd59-9a09-49bf-a6ce-e49f3aaaebe4" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.pharming.com/role/StatementofchangesinequityStatement" xlink:type="simple" xlink:href="pharm-2023-12-31.xsd#StatementofchangesinequityStatement"/>
  <link:calculationLink xlink:role="http://www.pharming.com/role/StatementofchangesinequityStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_pharm_TotalTransactionsWithOwnersRecognizedDirectlyInEquity_23caa0bb-ded3-4d09-ae05-061110265f0f" xlink:href="pharm-2023-12-31.xsd#pharm_TotalTransactionsWithOwnersRecognizedDirectlyInEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseThroughTransferToStatutoryReserve_e7732394-84e5-4a51-85f1-6a7ef3887313" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughTransferToStatutoryReserve"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pharm_TotalTransactionsWithOwnersRecognizedDirectlyInEquity_23caa0bb-ded3-4d09-ae05-061110265f0f" xlink:to="loc_ifrs-full_IncreaseDecreaseThroughTransferToStatutoryReserve_e7732394-84e5-4a51-85f1-6a7ef3887313" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_pharm_OptionsExercisedAndLtipSharesIssued_f76145c3-ef0a-420e-afe9-ee9bfebb6fd1" xlink:href="pharm-2023-12-31.xsd#pharm_OptionsExercisedAndLtipSharesIssued"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pharm_TotalTransactionsWithOwnersRecognizedDirectlyInEquity_23caa0bb-ded3-4d09-ae05-061110265f0f" xlink:to="loc_pharm_OptionsExercisedAndLtipSharesIssued_f76145c3-ef0a-420e-afe9-ee9bfebb6fd1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions_e5a7035c-2398-4ffb-a423-610ce1163ba5" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pharm_TotalTransactionsWithOwnersRecognizedDirectlyInEquity_23caa0bb-ded3-4d09-ae05-061110265f0f" xlink:to="loc_ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions_e5a7035c-2398-4ffb-a423-610ce1163ba5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DecreaseIncreaseThroughTaxOnSharebasedPaymentTransactions_69142682-3665-4ca4-a2f0-02922d6497d9" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DecreaseIncreaseThroughTaxOnSharebasedPaymentTransactions"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_pharm_TotalTransactionsWithOwnersRecognizedDirectlyInEquity_23caa0bb-ded3-4d09-ae05-061110265f0f" xlink:to="loc_ifrs-full_DecreaseIncreaseThroughTaxOnSharebasedPaymentTransactions_69142682-3665-4ca4-a2f0-02922d6497d9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.pharming.com/role/StatementofcashflowsindirectmethodStatement" xlink:type="simple" xlink:href="pharm-2023-12-31.xsd#StatementofcashflowsindirectmethodStatement"/>
  <link:calculationLink xlink:role="http://www.pharming.com/role/StatementofcashflowsindirectmethodStatement" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForFinanceCosts_5cbfd04c-1a96-4f5e-ab0f-a7f1ed89b204" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForFinanceCosts"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForFinanceCosts_5cbfd04c-1a96-4f5e-ab0f-a7f1ed89b204" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForFinanceIncome_fea4aa99-dfc8-40ad-9c45-efe18ed6b06c" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForFinanceIncome"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForFinanceIncome_fea4aa99-dfc8-40ad-9c45-efe18ed6b06c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDepreciationAndAmortisationExpenseAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_defdf361-19c9-4fdd-9d47-78f5047af074" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForDepreciationAndAmortisationExpenseAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForDepreciationAndAmortisationExpenseAndImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_defdf361-19c9-4fdd-9d47-78f5047af074" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForFairValueGainsLosses_a673b689-5e26-47b4-b2b7-b9d95c310675" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForFairValueGainsLosses"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForFairValueGainsLosses_a673b689-5e26-47b4-b2b7-b9d95c310675" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForSharebasedPayments_70ad5b32-8093-45b2-bb21-2d0fcd99e261" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForSharebasedPayments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForSharebasedPayments_70ad5b32-8093-45b2-bb21-2d0fcd99e261" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_b0a0b796-7d0a-40b7-a379-199f2d681a9d" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_ProfitLossBeforeTax_b0a0b796-7d0a-40b7-a379-199f2d681a9d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForUndistributedProfitsOfAssociates_3f99feaf-5388-4437-ba8c-d79152bee451" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForUndistributedProfitsOfAssociates"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForUndistributedProfitsOfAssociates_3f99feaf-5388-4437-ba8c-d79152bee451" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAdjustmentsForNoncashItems_6e8d1d90-2f02-4fa9-8a51-54b545f4d5de" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherAdjustmentsForNoncashItems"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_OtherAdjustmentsForNoncashItems_6e8d1d90-2f02-4fa9-8a51-54b545f4d5de" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates_e80ad7c9-b968-4945-8a4a-40495af272c7" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates_e80ad7c9-b968-4945-8a4a-40495af272c7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets_4c1ed41d-86dc-43a3-bf02-4dbf40073aa3" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_b5d66ebc-87e3-485e-a750-b3ecbed32208" xlink:to="loc_ifrs-full_AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets_4c1ed41d-86dc-43a3-bf02-4dbf40073aa3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_fa2f895b-5c62-402e-ab61-b3751667c2ea" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseInWorkingCapital"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables_cadef8cf-f36e-44c9-b912-f7b46b72da96" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_fa2f895b-5c62-402e-ab61-b3751667c2ea" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables_cadef8cf-f36e-44c9-b912-f7b46b72da96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInDecreaseIncreaseInRestrictedCashAndCashEquivalents_15bb69c7-7e5a-4f1c-b14a-ae9956da2ad2" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInDecreaseIncreaseInRestrictedCashAndCashEquivalents"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_fa2f895b-5c62-402e-ab61-b3751667c2ea" xlink:to="loc_ifrs-full_CashFlowsFromUsedInDecreaseIncreaseInRestrictedCashAndCashEquivalents_15bb69c7-7e5a-4f1c-b14a-ae9956da2ad2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInInventories_2fbfadf8-5ef6-48c7-97e0-1ce8d1f65821" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInInventories"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_fa2f895b-5c62-402e-ab61-b3751667c2ea" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInInventories_2fbfadf8-5ef6-48c7-97e0-1ce8d1f65821" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables_a20cbdda-50fc-4e89-a6d4-586ecbd21f25" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_fa2f895b-5c62-402e-ab61-b3751667c2ea" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables_a20cbdda-50fc-4e89-a6d4-586ecbd21f25" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfFinancialInstrumentsClassifiedAsInvestingActivities_d515de43-50eb-4050-8655-1f8c6d4d2c59" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfFinancialInstrumentsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:to="loc_ifrs-full_PurchaseOfFinancialInstrumentsClassifiedAsInvestingActivities_d515de43-50eb-4050-8655-1f8c6d4d2c59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_44d06cdb-dd90-446f-9a10-05a0a1616944" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:to="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_44d06cdb-dd90-446f-9a10-05a0a1616944" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSalesOfInterestsInAssociates_119370be-0066-4971-9ca4-d9fdcf45e9f7" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSalesOfInterestsInAssociates"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:to="loc_ifrs-full_ProceedsFromSalesOfInterestsInAssociates_119370be-0066-4971-9ca4-d9fdcf45e9f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities_205e7350-1f42-4484-8b10-5ce8b797a64e" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:to="loc_ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities_205e7350-1f42-4484-8b10-5ce8b797a64e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSalesOrMaturityOfFinancialInstrumentsClassifiedAsInvestingActivities_1b1657a8-cbbd-431f-a0d8-caf23e87a159" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSalesOrMaturityOfFinancialInstrumentsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:to="loc_ifrs-full_ProceedsFromSalesOrMaturityOfFinancialInstrumentsClassifiedAsInvestingActivities_1b1657a8-cbbd-431f-a0d8-caf23e87a159" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities_01faa8f2-e675-48b3-9ce2-4a82e061c827" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_2133118a-79e1-4f19-82cb-05a364490845" xlink:to="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities_01faa8f2-e675-48b3-9ce2-4a82e061c827" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_9dfe1a65-0647-4a80-a8d3-97fbbd1a517d" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestPaidClassifiedAsFinancingActivities_0c9e87f3-dbe9-4766-953b-f527f45a7271" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_InterestPaidClassifiedAsFinancingActivities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_9dfe1a65-0647-4a80-a8d3-97fbbd1a517d" xlink:to="loc_ifrs-full_InterestPaidClassifiedAsFinancingActivities_0c9e87f3-dbe9-4766-953b-f527f45a7271" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_fba3290e-2fcb-4d26-a39d-24c3ac22c097" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_9dfe1a65-0647-4a80-a8d3-97fbbd1a517d" xlink:to="loc_ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities_fba3290e-2fcb-4d26-a39d-24c3ac22c097" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromIssuingOtherEquityInstruments_6609e0e8-5965-42f7-bfaa-f9006d7d6814" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromIssuingOtherEquityInstruments"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_9dfe1a65-0647-4a80-a8d3-97fbbd1a517d" xlink:to="loc_ifrs-full_ProceedsFromIssuingOtherEquityInstruments_6609e0e8-5965-42f7-bfaa-f9006d7d6814" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_03ba4d6e-e2d5-44bf-b29a-a5f483a2a1f6" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_af105c35-0b57-4656-8b0b-e28abc0a927b" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseInWorkingCapital"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_03ba4d6e-e2d5-44bf-b29a-a5f483a2a1f6" xlink:to="loc_ifrs-full_IncreaseDecreaseInWorkingCapital_af105c35-0b57-4656-8b0b-e28abc0a927b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_5dcd16ea-50fe-4be3-b993-7373674802de" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_03ba4d6e-e2d5-44bf-b29a-a5f483a2a1f6" xlink:to="loc_ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital_5dcd16ea-50fe-4be3-b993-7373674802de" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_5d349e32-1389-44a5-99f5-10969794dce7" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_03ba4d6e-e2d5-44bf-b29a-a5f483a2a1f6" xlink:to="loc_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_5d349e32-1389-44a5-99f5-10969794dce7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestReceivedClassifiedAsOperatingActivities_513d42eb-4e0e-4499-bf8b-7ccd585a58fd" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_InterestReceivedClassifiedAsOperatingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_03ba4d6e-e2d5-44bf-b29a-a5f483a2a1f6" xlink:to="loc_ifrs-full_InterestReceivedClassifiedAsOperatingActivities_513d42eb-4e0e-4499-bf8b-7ccd585a58fd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges_4a0d0c20-2c7c-4633-89d6-80eff574ead9" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_8e815a33-bc42-4977-9f25-27441f919d7a" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges_4a0d0c20-2c7c-4633-89d6-80eff574ead9" xlink:to="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_8e815a33-bc42-4977-9f25-27441f919d7a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_68dbf245-8b8a-46c8-aa28-0ec88066b1ea" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges_4a0d0c20-2c7c-4633-89d6-80eff574ead9" xlink:to="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_68dbf245-8b8a-46c8-aa28-0ec88066b1ea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_480dc857-6cf6-44ae-9d4f-8618d7e89871" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges_4a0d0c20-2c7c-4633-89d6-80eff574ead9" xlink:to="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_480dc857-6cf6-44ae-9d4f-8618d7e89871" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
