<?xml version="1.0" encoding="utf-8"?>
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    <loc xlink:type="locator" xlink:href="plus500ltd-2021-12-31.xsd#plus500ltd_NoncurrentShareBasedCompensation" xlink:label="plus500ltd_NoncurrentShareBasedCompensation" />
    <loc xlink:type="locator" xlink:href="plus500ltd-2021-12-31.xsd#plus500ltd_TradePayablesDueToClients" xlink:label="plus500ltd_TradePayablesDueToClients" />
    <loc xlink:type="locator" xlink:href="plus500ltd-2021-12-31.xsd#plus500ltd_ServiceSuppliers" xlink:label="plus500ltd_ServiceSuppliers" />
    <labelArc xlink:type="arc" xlink:from="plus500ltd_NoncurrentShareBasedCompensation" xlink:to="label_plus500ltd_plus500ltdNoncurrentShareBasedCompensation_Standard" order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" />
    <labelArc xlink:type="arc" xlink:from="plus500ltd_CurrentShareBasedCompensation" xlink:to="label_plus500ltd_plus500ltdCurrentShareBasedCompensation_Standard" order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" />
    <labelArc xlink:type="arc" xlink:from="plus500ltd_ServiceSuppliers" xlink:to="label_plus500ltd_plus500ltdServiceSuppliers_Standard" order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" />
    <labelArc xlink:type="arc" xlink:from="plus500ltd_TradePayablesDueToClients" xlink:to="label_plus500ltd_plus500ltdTradePayablesDueToClients_Standard" order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" />
    <label xlink:label="label_plus500ltd_plus500ltdNoncurrentShareBasedCompensation_Standard" id="plus500ltd_plus500ltdNoncurrentShareBasedCompensation_Standard" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en">Non-current share-based compensation</label>
    <label xlink:label="label_plus500ltd_plus500ltdCurrentShareBasedCompensation_Standard" id="plus500ltd_plus500ltdCurrentShareBasedCompensation_Standard" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en">Current share-based compensation</label>
    <label xlink:label="label_plus500ltd_plus500ltdServiceSuppliers_Standard" id="plus500ltd_plus500ltdServiceSuppliers_Standard" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en">Service suppliers</label>
    <label xlink:label="label_plus500ltd_plus500ltdTradePayablesDueToClients_Standard" id="plus500ltd_plus500ltdTradePayablesDueToClients_Standard" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en">Trade payables – due to clients</label>
  </labelLink>
</linkbase>