nana
1
Letter from the Chairmanship
Letter from the CEO
Management’s review
Management’s statement 
Independent auditor’s Report 
Financial statements of the Parent Foundation 
Income statement and statement of comprehensive income for the year
–  
 
 
 
Notes 
Consolidated financial statements Novo Nordisk Foundation Group 
Income statement and statement of comprehensive income for the year
- 

 
Cash flow statement 
Notes
Annex A (a part of Management’s Review) 
Table of Content
5
2
Benefitting people and society



-

that derive from its ownership of and investment in companies and




 Novonesis
-



-









-sci-
search and the

Points of focus in 2025
 








nternational


- 

ellcome
-





 these events
-




-year period and go towards pro-




tion over 


 
-
e
-
Letter from the Chairman-
ship
5
3





rns on its in-








Chair
Vice Chair
5
4
Activity highlights in 2025
-
awarding a total



Grants in open competition
-
-

-tier re-





--
tions
-

-
i-

plinary -career
interdisciplinary researchers long-
-



-
tion -
lating innovative research while strengthening the regenerative medi-

AI and quantum computing
-of-the--


ir research against



-
 



Fighting cardiometabolic disease






-
 
-



Major partnerships and collaborations

-

-grown school meals



mil-
 


ng



-
tor (Gr--
-

priority pathogens and are among the leading  
AMR-
Letter from the CEO
5
5
Gr-






-powered platform will provide a state-of-the


Supporting major initiatives in Denmark

one-point-of-


research as well as driving personalised medicine and innovative

 



across 

mitted towards the green


Cli-
mate 

New organisational structure

-






5
6
The Foundation’s purpose and vision



ment in companies
 


phil-
:
» 
medical research
» 
» 
Mission and strategic goals for the Foundation’s
activities
 a two-pronged mission re-
lating to its corporate as well as its philanthropic activities
Corporate mission
» nesis A/S
» 
sets
» 

Philanthropic mission




phil-
anthropic 

» aims to improve the prevention
and treatment of  health as well as
a healthy life and treatment
In addition to strengthening prevention and management of car-
decreasing
the  and on advancing and
 
» aims 

-yield
 climate

transition in society
» 








ternational scope
Overarching principles for the Foundation’s phil-
anthropic activities

an array of scientific and non-


partners that are:
Excellent:

» 


porting world-
rating with relevant o

Innovative:

» 



Management’s review
5
7
innovative approaches are sometimes necessary to solve

Collaborative:
 
» 



and more effect
Knowledge-sharing:
 
» 





Diverse:

» 




Grants awarded
-
  
 
 and  -

search
5
8



n


Novo Holdings A/S’ income stems from:
» nesis A/S as well as
-
» and Capital Investment ortfolios
-award-




Novo Holdings A/S manages the assets and wealth of 


A/S and Novonesis 



nesis




nesis A/S
-
-awarding strat-

Figure
1 - Organisation and cash flows in the Novo Nordisk Foundation Group in 2025

nesis -

Organisation and governance of the Novo Nordisk Foundation Group
5
9



– t
Board deems this necessary – 
nesis A/S or other companies in which Novo

The has 

cthe
 
Novo Holdings A/S



-of-con-
 and 
Novo Holdings A/S
Novo Holdings is a holding and investment company that manages the


-t

Novo Holdings is the controlling 
vonesis an investment
portfolio with a long-term 
life science companies at all stages of development and
real estate and infra-

Novo Nordisk A/S



treatments 
 fiting
The p
their 

they 
Novo employs  peo-
 5
Novonesis A/S
Novonesis is the world leader 
of enzymes microorganismswhich
among other things 
ce more from less– 
 - Novonesis A/S





5
it employed  people
Changes in the Leadership and Board of Directors
of Novo Nordisk A/S during 2025







 General Meet-
-



that the company is optimally positioned to sec










- 
» 
implementing its transformation plans and regaining the

» 



5
10
Financial results
5 
 million million in  roceeds from
 was down 5 million in
  million 5
Total million in 5
Table 1. Key figures and financial ratios for the Novo Nordisk Foundation
(DKK million)
 

 

 

 

 


 

 

 

 
Grant
  

 

 

 investment assets val-
 5
nesis 
 5
5
The ratio of cost was  relative 
55 relative to grants were





s 
tion on and In re-
 and Com-
services 
5  
 were 5

Novo Nordisk Foundation:
Financial results, grants and payouts
5
11
Grants and payouts

-
- mil-
lion  to million in In grant 
 million5 net grant-
s  

 million in   5In 
s grant awarding to increase 
 million while g mil-
lion

as the Green Tri-
ll  inter-
nationally
5


»  million
and other medical research;
»  m

grant
recipients 5: 
loads/Novo----- The list



Figure
2 – Grants and pay-outs of the Novo Nordisk Foundation, 2021-2025 (DKK million)






    
Grant awards 
5
12


nesis 
The Novo Nordisk Foundation Group
Highlights
de-
creased 5   
5The net profit for  illion was 
the depreciation of 
  55  5
  average -time
employees within the g  to  in
5
 5 had strong headwind
from perfor-
Novonesis and Novo Holdings 
is  5
Novo Holdings A/S
Financial results






capital diversify its portfolio and to en-


Life science investments

nies within  areas:
» -
and profit-

tive --

» 

o-

» h Investments  invest-
ment vertical at the  invests 
technology 
» Asia in 
with the other investment verticals at Novo Holdings in the Asia
Region
» 

» 
-

-
the --

de 
 to   5the
 
to historical levels
Capital investment activities




diversifying 

real estate and as-
sets 5capital 
 

Financial key figures and ratios
Net profit for the year in Novo Holdings A/S   
5 against 5 
Highlights and financial results within the
Novo Nordisk Foundation Group
5
13
Table 2. Key figures and financial ratios for Novo Holdings A/S* (DKK mil-
lion)
 
 

- 
 
 
 
 
 
 
 
 

: 

----









- 

   


 :   :  


5
14
Novo Nordisk A/S
Financial results
Operating profit deincreased
constant  within
the range of the  of a - 5
in constant 

5 

 – a decrease from 
of   in5
  

5-
Financial key figures and ratios
Table 3. Key figures and financial ratios for Novo Nordisk A/S (DKK mil-
lion)
 

289,456 271,764

19,608 18,639

309,064 290,403

127,658 128,339

102,434 100,988

194,047 143,486

542,902 465,630

41% 44%

36% 31%

: 

-


5
15
Novonesis A/S
Financial results
5  
growth
  of  5 was 
ended at 
of –

nesis nesi
5-
Financial key figures and ratios
Table 4. Key figures and financial ratios for Novonesis A/S (DKK million)
 

31,050 27,473

4,358 2,192

81,069 80,092

122,098 108,902

21% 17%

66% 74%

nesi: 

-
Novo
nesi

5
16
Outlook for the Novo Nordisk Foundation Group



 more detail in the com-
5 – -5
Business related and financial risks

those of 






-’

 As part of their integrated 


pages - 5
Novonesis 
which means that Novonesis’ 
Novonesis f
sess

nesis 
Novonesis’ 5-
 in the Novonesis 5
Prospects for the Novo Nordisk Foundation’s and Novo Holdings A/S’
results


A/S and Novonesis A/S Novo Holdings receives divi-
dends
any of -
-awarding

 
gramme and Novo 

 
ment Assets portfolio are 
and  ap-
 
pany development and 
Novo Holdings  on par or
their 
in
 -decrease in sales
and in 
 
5 –  
profit for   – 

5
17
The Novo Nordisk Foundation Group’s corporate social responsibility
s 
-awarding policy


economically


development 
cordance with Section  





Novo-
nesis A/S 
 among other

 infor-
mation in the
 es its

-holdings-performance-re-
port- https://as-
-holdings---
- and
-report
Diversity policy in the Novo Nordisk Foundation Group







nt and development processes in the







-

--por-
-
Novonesis A/S: --
policies
Diversity policy for the Novo Nordisk Foundation and Novo Holdings
A/S
The 



- 
 of perspectives is

the 


Management 
-policy/



ring to 
means that we at this level already now live 
of 
cles of Association 
and 
to attract more female




Beyond gender diversity 



5
18
Table 5. Gender diversity in the Novo Nordisk Foundation
   
 



      



      


    

      


    

      NA

--
Diversity in Novo Holdings A/S
Holdings’
 
leadership level consists of 


diverse 
principles 


Data ethics in the Novo Nordisk Foundation Group





Novo Nordisk Foundation
Tmaintains a data ethics policy which




principles de
cesses personal and non-ed
ead more at: https://novo-
-ethics-and-ai-policy/
 on

 to
appropriate 

Novo Holdings A/S
To cope with the challenges that arise from the fast-moving technolog-



-on-data-
Novo Nordisk A/S



adopted a set of principles for data and AI et
cision-


ead more on: 
principles
Novonesis A/S
Novonesis les for
the ethical management of data in Novonesis 
 
report 

The Foundation’s Board of Directors, Committees and Executive Manage-
ment
5
19
Board of Directors
The Board in 2025
ten seven
elected  Articles of Association (“Articles”) and
three employee Novo-
nesis 
 research 
in medical research

Chairmanship



Recommendations on foundation governance
t

governance nterprise 
does not comply with a specific recommendation
in its 

the recommendation on the appointment 
appointed for a

coordination with the  
rectors has decided a one year 
 The Board deems that an election period of one


with the
: 
-the--on-
dation-governance/
Gender Diversity


 and 
 5elected
 was 
Nomination Committee
The Nomination Committee consists of  from the
B

The Committee is 
  


Board and reviewing Novo Holdings A/S’ nominations for its Board of
 
rectors with nominating candidates for entities 
tion has 
The Nomination Committee assists the Board 

Art Committee
In 5decided to  the
Art Committee 
date to a w 
Communications policy



The Chair serves as
s 
s 
tion in  in relation to grant-giving poli-
cies and strategies that ha



Remuneration
T was
revised as of  5 and is 
 5 The fee

s 
In 
connection with a Board meeting or Board committee meeting receive


5
20
Table 6. Board fees, Novo Group 2025 (DKK)
Position
   Novonesis A/S

   

   

   

Table 7. Remuneration to Board members within the Novo Group 2025 (DKK thousand)




A/S

A/S
Novonesis
A/S
Committees




    ,

  ,

   ,

 

 

  

  

 

   

 

  

  ,
,    , ,
Not
  

   

 : M  

M 

Novonesis A/S   

Novonesis A/S 

Novonesis 

-

5
21
Table 8. Members of the Novo Nordisk Foundation Board of Directors, 2025



sion

term

/





-IB





B 

as



Vice B

B













-

 









-

A/S 












s





MSc




Ma











-













5
22
Table 8. Members of the Novo Nordisk Foundation Board of Directors, 2025



sion

term
Managerial and other board assignments/Competencies (only for members ap-
pointed under the provisions of the Articles of Association)

















tion
A/S 

s 






 













-

-in-–






-










































-

5
23
Table 8. Members of the Novo Nordisk Foundation Board of Directors, 2025



sion

term

/








Ma


at 







Ma


  at Novonesis 






Ma


at 

5
24
Committees and panels of the Novo Nordisk Foundation
 
 
cerning assessment of grant applications -alone
-awarding decisions in connec-

  and Articles
of Association -we-are/articles-of-association/
 academic research
 
-we--for-
Table 9. Fees for committee and panel members in 2025 DKK thousands















Committee
on Innovation
































































5
25
Table 9. Fees for committee and panel members in 2025 DKK thousands
Com








































 Committee   serves as m



Executive Management
5  C 
Thomsen  
rThe Board
approves the appointment of the C 
of the ’s -

5
26
Table 10. Key figures and financial ratios in the Novo Nordisk Foundation Group

    

    

    

   - 

    

-     

    

-     

    

    

to      


    

- - - - -

-  - - -


     

-
terests)
    

ratio -     

    
Annual Report 2025
27
Management’s statement
The Board of Directors and Executive Management have today considered and adopted the Annual Report of Novo Nordisk Fo
nden
for the finan-
cial year 1 January
- 31 December 2025.
The
Annual Report is prepared in accordance with IFRS Accounting Standards as adopted by the EU and further requirements in the Danish Fi-
nancial Statements Act.
In our opinion, the Consolidated Financial Statements
and Financial Statements give a true and fair account of the Group’s and the Parent Founda-
tion’s assets and liabilities as well as financial position as per 31 December
2025, as well as of the Group’s and the Parent Foundation’s operations
and cash flows for the financial year
2025.
In our opinion, the Management’s review includes a true and fair account of the development in the Group’s and the Parent Fou
ndation’s opera-
tions and financial circumstances, as well as a description of the most significant risks and elements of uncertaint
y facing the Group and the Parent
Foundation.
Hellerup, 27 May 2026
Executive Management:
Mads Krogsgaard Thomsen
(CEO)
Board of Directors:
Lars Rebien Sørensen
(Chair)
Lars Henrik Munch
(Vice Chair)
Steen Riisgaard
Nana Bule Sejbæk
Barbara Casadei
Lars Green
Christopher A. Voigt Ole Jakob Müller Mads Boritz Grøn
Stig Strøbæk
Annual Report 2025
28
To the Board of Directors of Novo Nordisk Fonden
Opinion
In our opinion, the Consolidated Financial Statements and the Parent Foundation’s Financial Statements give a true and fair view of the Group’s
and the Parent Foundation’s financial position at 31 December 2025 and of the results of the Group’s and the Parent Foundation’s operations and
cash flows for the financial year 1 January to 31 December 2025 in accordance with IFRS Accounting Standards as adopted by the EU and further
requirements in the Danish Financial Statements Act.
We have audited the Consolidated Financial Statements and the Parent Foundation’s Financial Statements of Novo Nordisk Fonden for the finan-
cial year 1 January - 31 December 2025, pp 30-107, which comprise income statement and statement of comprehensive income, balance sheet,
statement of changes in equity, cash flow statement and notes, including material accounting policy information, for both the Group and the Parent
Foundation ( “financial statements”).
Basis for Opinion
We conducted our audit in accordance with International Standards on Auditing (ISAs) and the additional requirements applicable in Denmark.
Our responsibilities under those standards and requirements are further described in the Auditor’s Responsibilities for the Audit of the Financial
Statements section of our report. We are independent of the Group in accordance with the International Ethics Standards Board for Accountants’
International Code of Ethics for Professional Accountants (IESBA Code) and the additional ethical requirements applicable in Denmark, and we
have fulfilled our other ethical responsibilities in accordance with these requirements and the IESBA Code. We believe that the audit evidence we
have obtained is sufficient and appropriate to provide a basis for our opinion.
Statement on Management’s Review
Management is responsible for Management’s Review, pp 2-29 and pp 108-118.
Our opinion on the financial statements does not cover Management’s Review, and we do not express any form of assurance conclusion thereon.
In connection with our audit of the financial statements, our responsibility is to read Management’s Review and, in doing so, consider whether
Management’s Review is materially inconsistent with the financial statements or our knowledge obtained during the audit, or otherwise appears to
be materially misstated.
Moreover, it is our responsibility to consider whether Management’s Review provides the information required under the Danish Financial State-
ments Act.
Based on the work we have performed, in our view, Management’s Review is in accordance with the Consolidated Financial Statements and the
Parent Foundation's Financial Statements and has been prepared in accordance with the requirements of the Danish Financial Statements Act. We
did not identify any material misstatement in Management’s Review.
Management’s Responsibilities for the Financial Statement
Management is responsible for the preparation of Consolidated Financial Statements and Parent Foundation’s Financial Statements that give a
true and fair view in accordance with IFRS Accounting Standards as adopted by the EU and further requirements in the Danish Financial State-
ments Act, and for such internal control as Management determines is necessary to enable the preparation of financial statements that are free
from material misstatement, whether due to fraud or error.
Independent auditor’s re-
port
Annual Report 2025
29
In preparing the financial statements, Management is responsible for assessing the Group’s and the Parent Foundation’s ability to continue as a
going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting in preparing the finan-
cial statements unless Management either intends to liquidate the Group or the Parent Foundation’s or to cease operations, or has no realistic
alternative but to do so.
Auditor’s Responsibilities for the Audit of the Financial Statements
Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether
due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guar-
antee that an audit conducted in accordance with ISAs and the additional requirements applicable in Denmark will always detect a material mis-
statement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could
reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements.
As part of an audit conducted in accordance with ISAs and the additional requirements applicable in Denmark, we exercise professional judge-
ment and maintain professional scepticism throughout the audit. We also:
• Identify and assess the risks of material misstatement of the financial statements, whether due to fraud or error, design and perform audit
procedures responsive to those risks, and obtain audit evidence that is sufficient and appropriate to provide a basis for our opinion. The risk
of not detecting a material misstatement resulting from fraud is higher than for one resulting from error as fraud may involve collusion, for-
gery, intentional omissions, misrepresentations, or the override of internal control.
• Obtain an understanding of internal control relevant to the audit in order to design audit procedures that are appropriate in the circum-
stances, but not for the purpose of expressing an opinion on the effectiveness of the Group’s and the Parent Foundation’s internal control.
• Evaluate the appropriateness of accounting policies used and the reasonableness of accounting estimates and related disclosures made by
Management.
• Conclude on the appropriateness of Management’s use of the going concern basis of accounting in preparing the financial statements and,
based on the audit evidence obtained, whether a material uncertainty exists related to events or conditions that may cast significant doubt on
the Group’s and the Parent Foundation’s ability to continue as a going concern. If we conclude that a material uncertainty exists, we are re-
quired to draw attention in our auditor’s report to the related disclosures in the financial statements or, if such disclosures are inadequate, to
modify our opinion. Our conclusions are based on the audit evidence obtained up to the date of our auditor’s report. However, future events
or conditions may cause the Group and the Parent Foundation’s to cease to continue as a going concern.
• Evaluate the overall presentation, structure and contents of the financial statements, including the disclosures, and whether the financial
statements represent the underlying transactions and events in a manner that gives a true and fair view.
• Plan and perform the group audit to obtain sufficient appropriate audit evidence regarding the financial information of the entities or business
units within the group as a basis for forming an opinion on the Consolidated Financial Statements and the Parent Foundations Financial State-
ments. We are responsible for the direction, supervision and review of the audit work performed for purposes of the group audit. We remain
solely responsible for our audit opinion.
We communicate with those charged with governance regarding, among other matters, the planned scope and timing of the audit and significant
audit findings, including any significant deficiencies in internal control that we identify during our audit.
Hellerup,
27 May 2026
PricewaterhouseCoopers
Statsautoriseret Revisionspartnerselskab
CVR
-nr. 33 77 12 31
Lars Baungaard
State
Authorised Public Accountant
mne23331
Tue Stensgård Sørensen
State Authorised Public Accountant
mne32200
5
30
Financial statements of
the
Parent Foundation

5
31
Income statement and statement of comprehensive income for the year
1 January – 31 December
DKK million
Note 2025 2024

 
Administration costs

- -

- -
Result of primary activities
5,405 4,996

 
Profit before tax
8,038 10,791

Profit for the year
8,038 10,791
Proposed distribution of profit

 


- 
8,038 10,791
5
32
Balance sheet at 31 December
DKK million
Note 2025 2024
Assets

 

 

 

 

 

Total non
-current assets
14,687 22,021
I

 

 

 

 

 
Total current assets
47,314 39,528
Total assets
62,001 61,549
Equity and liabilities

 

 

 
Total equity
34,972 37,760

 
Total non
-current liabilities
 

 

 

 

 
Total current liabilities
8,999 7,656
Total liabilities
27,029 23,789
Total equity and liabilities
62,001 61,549



5
33
Statement of changes in equity at 31 December
DKK million
Note Capital base
Retained
earnings
Reserve for
future grants
Total
2024

   

  

- -
Equity as of 31 December
22 22,738 15,000 37,760
2025

   

-  

- -
Equity as of 31 December
22 19,950 15,000 34,972
5
34
Cash flow statement for the year ended 31 December
DKK million
2025 2024
Profit for the year
8,038 10,791


- -


- -
Cash flow before changes to working capital
5,413 5,010

-

- -

 
Cash flow from operating activities
5,420 5,049

 

- -

 

- -


-


- -
Cash flow from investing activities
2,273 1,876

- -

 
Cash flow from grants
-7,659 -6,937
Net cash flow
34 -12

 
Cash and cash equivalents at the end of the year
63 29
5
35
Notes
Note 1 Accounting policies
The
policies 

Inve
stments in subsidiaries
Ithe dividends 

Grants
Grants are recogniss

Note 2 Employee costs
DKK million
2025 2024

 

-   


committees  

355 313


 - -
Total salaries and fees
350 310

 

-term incentives  



16 19

6
Total
23 25

-










-
Average number of full
-time employees 270 245
5
36
Note 3 Fees to Statutory Auditors
DKK million
2025 2024

 

 

 

 
Fees to statutory auditors
2.1 1.8
Note 4 Net financial items
DKK million
2025 2024

 

 


Net financial items
2,633 5,795
Note 5 Grants
DKK million
2025 2024
Grants awarded in the year:

 

 

 
Total grants awarded in the year
10,913 8,150

- -

- 
Grants awarded in the year after adjustments
10,826 8,078
Grant liability at the
beginning of year 23,666 22,522

- -

-

 
Grant liability at the end of year
26,832 23,666
Expected pay out of the Grant liability

 
-  

 
26,832 23,666
5
37
Note 6 Investments in subsidiaries
DKK million
2025 2024

 

 
Carrying amount at the end of the year
3,988 3,263

-

-






Note 7 Contingent liabilities





 



  

Note 8 Related party transactions
DKK million
2025 2024









-


Novo Holdings A/S

 

 

 

  

 

n   

 

 


Danish Centre for AI Innovation A/S




5
38
BioInnovation Institute
Grant
 
Novo Holdings Business & People Support P/S





NNF India A/S

Quantum Foundry A/S

Novo Nordisk Foundation Cellerator P/S


The Novo Nordisk Group


The Novonesis Group





n no transac-






Note 9 Other disclosures
Novo Nordisk Foundation
Subsidiaries
Company name
Country
Ownership (%) voting rights




Innovation A/S











5
39













 

of votesshall have the casting vote
Tax



5
40
Income statement and statement of comprehensive income for the year  - 
Consolidated financial
statements Novo Nordisk
Foundation
Group
5
5
41
Income statement and statement of comprehensive income for the year 1 January - 31
December
DKK million
Note 2025 2024
Income statement

384,724 342,798


-105,139 -76,114
Gross profit
279,585 266,684


-71,569 -68,108


-55,852 -52,071


-14,235 -9,834

8,648 17,879


-13,997 -8,280
Operating profit
132,580 146,270

4,334 11,532

10,566 6,761

-14,087 -11,313
Profit before income taxes
133,393 153,250

-29,073 -27,079
Net profit
104,320 126,171

Non
-
76,343 74,118

27,977 52,053
Net profit
104,320 126,171
Statement of comprehensive income
Net profit
104,321 126,171
Other comprehensive income:


25 -120


-14,576 3,579

5,780 -1,833

4,557 -4,693

1,329 -123

-2,675 1,374
Other comprehensive income, net of tax
-5,560 -1,816
Total comprehensive income
98,760 124,355

Non
-

73,187 73,062

25,573 51,293
Total comprehensive income
98,760 124,355
5
42
Balance sheet at 31 December
DKK million
Note 2025 2024
Assets

273,809 255,533


255,496 212,484


26,277 25,465


1,295 7,449


171,066 150,497

12,371 14,622
Total non
-current assets
740,314 666,050
Inventories

60,692 52,264


82,780 85,769

1,168 3,568

6,381 3,785


6,846 6,361

17,313 17,629

677 10,652


39,303 37,254


0 87
Total current assets
215,160 217,369
Total assets
955,474 883,419
5
43
Balance sheet at 31 December
DKK million Note 2025 2024
Equity and liabilities

22 22

233,252 216,913

15,000 15,000

-2,991 -409
Total equity parent foundation
245,283 231,526
Non
-

213,295 179,701
Total equity
458,578 411,227


18,030 16,133


195,591 172,313

10,821 10,566


7,512 9,214

1,051 1,456


5,687 4,908
Total non
-current liabilities
238,692 214,590


26,416 15,727

25,733 36,383

9,499 21,541


50,880 46,234


2,057 7,776

195 1,711


8,802 7,533


1,204 485

133,418 120,212
Total current liabilities
258,204 257,602
Total liabilities
496,896 472,192
Total equity and liabilities
955,474 883,419



-






-




other  
44
Annual Report 2025
Statement
of
changes
in
equity
at
31
December
DKK million
2025
Capital
base
Retained
earnings
Reserve
for
future
grants
Currency
adjust-
ments
Cash
flow
hedges
Other
adjust-
ments
Total
other
compre-
hensive
income
Minority
interests
Total
Balance at the beginning of the year
22
216,913
15,000
541
-
1,430
481
-
409
179,701
411,227
Change in effective ownership
0
-
577
0
0
0
0
0
577
0
Balance at beginning of the year
22
216,336
15,000
541
-
1,430
481
-
409
180,278
411,227
Net
profit
0
17,151
10,826
0
0
0
0
76,343
104,320
Other comprehensive income
0
178
0
-
5,917
2,922
413
-
2,582
-
3,156
-
5,560
Total
comprehensive
income
0
17,329
10,826
-
5,917
2,922
413
-
2,582
73,187
98,760
Share-based payments
0
468
0
0
0
0
0
1,152
1,620
Tax related to equity postings
0
18
0
0
0
0
0
41
59
Purchase of treasury shares
0
-
578
0
0
0
0
0
-
1,552
-
2,130
Sale of treasury shares
0
86
0
0
0
0
0
246
332
Dividends
0
0
0
0
0
0
0
-
40,321
-
40,321
Grants, net
0
0
-
10,826
0
0
0
0
0
-
10,826
Business acquisitions and other adjust-
ments
0
-
407
0
0
0
0
0
264
-
143
Balance at the end of the year
22
233,252
15,000
-
5,376
1,492
894
-
2,991
213,295
458,578
2024
Balance at the beginning of the year
22
170,505
15,000
-
1,001
464
112
-
425
98,131
283,233
Change in effective ownership
0
-
3,897
0
0
0
0
0
703
-
3,194
Balance at beginning of the year
22
166,608
15,000
-
1,001
464
112
-
425
98,834
280,039
Net
profit
0
43,975
8,078
0
0
0
0
74,118
126,171
Other comprehensive income
0
-85
0
1,542
-
1,894
369
16
-
685
-
754
Total
comprehensive
income
0
43,890
8,078
1,542
-
1,894
369
16
73,432
125,417
Share-based payments
0
679
0
0
0
0
0
1,780
2,459
Tax related to equity postings
0
227
0
0
0
0
0
582
809
Purchase of treasury shares
0
4,470
0
0
0
0
0
-
14,491
-
10,021
Sale of treasury shares
0
72
0
0
0
0
0
210
282
Dividends
0
0
0
0
0
0
0
-
33,696
-
33,696
Grants, net
0
0
-
8,078
0
0
0
0
0
-
8,078
Business acquisitions and other adjust-
ments
0
967
0
0
0
0
0
53,049
54,016
Balance at the end of the year
22
216,913
15,000
541
-
1,430
481
-
409
179,701
411,227
45
Annual Report 2025
Cash flow statement
DKK million
Note
2025
2024
Operating
profit
132,580
146,270
Adjustment of non-cash items:
Depreciations, amortisation and impairment losses
9,
10
36,206
25,656
Other non-cash items
21
-
3,654
1,704
Income taxes paid
-
43,357
-
32,051
Interest received and other financial income
1,815
2,395
Interest paid and other financial expenses
-
4,294
-
5,218
Cash flow before changes to working capital
119,296
138,756
Increase/decrease in receivables
-
1,980
-
16,341
Increase/decrease in inventory
-
9,125
-
7,712
Increase/decrease trade in payables and other debt
5,196
14,730
Currency adjustments
7,497
1,379
Cash flow from operating activities
120,884
130,812
Business acquisitions
-12,923
-
124,294
Divestments
1,645
2,126
Purchase of financial assets - Life Science Investments
-11,525
-
9,614
Sale of financial assets - Life Science Investments
18,985
8,874
Purchase of financial assets - other
-
30,209
-
61,640
Sale of financial assets - other
16,043
73,853
Purchase of intangible assets
-
30,488
-
4,444
Purchase of tangible assets including investment property
-
66,611
-
52,241
Sale of tangible assets
148
191
Payments for marketable securities
-
498
-
19,028
Proceeds from sale of marketable securities
10,647
24,392
Cash flow from investing activities
-
104,786
-
161,825
Proceeds from borrowing
123,209
120,361
Repayment of borrowings
-
86,596
-
16,955
Purchase of treasury shares
-
2,130
-
10,021
Sale of treasury shares
332
282
Repayment leasing
-
625
-
365
Paid dividend to non-controlling interests
-
40,320
-
33,696
Purchase of non-controlling interests
0
-
3,983
Paid grant Novo Nordisk Foundation, net
-7,633
-
6,937
Net cash flow used in financing activities
-
13,763
48,686
Net cash generated from activities
2,335
17,673
Cash and cash equivalents at the beginning of the year
37,254
19,083
Reclassification of bank overdraft to financing activities
103
0
Exchange gains/(losses) on cash and cash equivalents
-
389
498
Cash
and
cash
equivalents
at
the
end
of
the
year
22
39,303
37,254
5
46
Notes
 
Net sales –  
 
 
 
 
 
 
 7
 

Investment property 
 
Associated companies 
 
Inventories 
 
Other provisions 
Borrowings 
ities
Other non-cash items 
 
 
 
Share- 
 
Related party transactions 
-controlling interest 
Assets held for sale 
 
 
 
5
47
Accounting policies
Principal accounting policies and key accounting
estimates

 

adopted 

Measurement basis


vestments 

T
consistently in the preparation of the consolidated financial statements

Principal accounting policies




Net sales (note )
)
)
5)
)
)
Applying materiality



sented in classes of similar items in the consolidated financial state-






Key accounting estimates and judgements

the preparation of the parent and consolidated financial statements










 the period in which the esti-
 Management co






 Management in Novo NordNovonesis
Management in
 regards the following as
 
the consolidated financial statements:
and provisions  (note
)
 in determinin when acq
ing  (n)

 (note )
 


transaction is an asset  (note 
)
 (note
5)
 (note
)
l
statements
5
48
Changes in accounting policies and disclosures
Adoption of new or amended IFRS
Management has assessed that 
s
 5 has not had a
significant effect on the consolidated financial statements



act on the
consolidated financial statements in the period of initial application






 

Changes to presentation of provisions for ‘sales deductions and prod-
uct returns’

presented as a separate line item to enhance clarity of presentation

en reclassified to the new

General policies
Principles of consolidation
The consolidated financial statements incorporate the financial state-
ments of the parent  
the the




-









sed inter-

Translation of foreign currencies
Functional and presentation currency

tion



the parent company
Translation of transactions and balances



transactions and from the translation at year-en


n-

Translation of Group companies





:
the 
;
the 
come at average to year-
Other Accounting policies
Research and development costs



 in the development of


-approval activ-





and impairment losses













5
49








porting date for

Financial assets and liabilities

lowing categories:
– 
– 
– other comprehensive income
Management determines the classification of its financial assets on ini-
tial recognition and re-

Recognition and measurement







ship
Financial assets 'at fair value through the income statement'



he end of the
assets held
for sale

assets are recognised in the income statement as financial income or




Financial assets 'at amortised cost'
-derivative
The
 -to-


d as non-

 they are


Financial assets 'at fair value through other comprehensive income'



Financial liabilities 'at fair value through the income statement'


Financial liabilities 'at amortised cost'


Financial assets (Investments)
two main types: ife Sci-
ence Investments and  and two minor types: other financial
assets and contract assets
Science Investments are defined as direct or indirect investments


Investments that do not meet the definition y are
defined as 
inancial assets that fall into the category of either life science or 
ties are recognised  
profit or recognised 
  please refer to
5
Financial definitions
Operating profit
Operating profit as percentage of sales
Net profit margin (incl. non-controlling interests)

Equity ratio
Total shareholders’ non-controlling interests) as a percent-
age of total assets at year-
Supplementary accounting policies for the parent
foundation
Investments in subsidiaries
In the financial statements of the parent 
are recognised at cost price and dividend received from

Gain and losses on sale of shares in  

5
50
Grants
Grants are recognised once the 
ligated 
 
5
51
Net sales and rebates
Gross-to-net sales reconciliation
DKK million
2025
2024
Gross sales



-
-
holesaler charge-
-
-

-
-

-
-

-
-
Non-
-
-
Total gross-to-
-
-
Net sales
384,724
342,798
Net sales geographical areas:



Region China


Region North America


Rest of the world


Total net sales by geographical area
384,724
342,798
Liabilities for sales deductions and product returns
DKK million
2025
2024
Sales deductions at beginning of the year
118,566
99,939




-
-

-
-

-

Sales deductions at the end of the year
131,368
118,566



Sales deductions and product returns
134,469
121,668




Pricing mechanisms in the US market


 
 
US Managed Care and Medicare
e pro-
 pre-



5
52
US wholesaler charge-backs
-
-

-
longer provides


 


 reflecting an as-
sessment  note  fo

US Medicaid rebates

olves interpretation of rele-
 

Other US and non-US discounts and sales returns

 

Accounting policy

sold 

 
single
on 








ises sales when the 

 -or-

ale-or-


ptance rates for
well
-


are rec-
ognised


-


Key accounting estimates and judgements
Estimate of sales deductions and provisions for sales rebates
 


5
53

 
As disclosed in note

 
 
ecame final and



-
 
 
 

 

Employee costs

Note  

 

-

 

-   

-   

 

 

 

-
-

- -

 


 

 

 

 

 

, 

-term incentives  



  

13 11

9 30

 

- 114,156 95,741
5
54
Accounting Policy

-

- 

Fees to statutory auditors

 

 

-

 

 

 

 



17 

 

113 
Amortisation, depreciation and impairment losses

 


 

 

 

 

 

 
Return on investment activities and other operating income

 

 

 
  
Financial income and expenses
Financial income

 

-
5
55
Interest income
 

 

 

 

 
Financial expenses

 

 

 

 

 

 

 
Accounting policy

ash flow hedged
transferred from other comprehensive income to the income statement when the hedged transaction is recognised in th




-

Income taxes

 

 

- -

 

- -

 

 -

- -






are  

in 


 

- -
5
56
Non
--- - -

- -
Effective tax rate
21.3% 17.5%
Accounting policy

in provisions for





ompanies and














Key accounting estimates and judgements

 




the c
deviate and depends 
Development in deferred income tax assets and liabilities
DKK million
2025 2024

 

 

- -

 

- 

- -

- 
Net deferred tax asset/(liability) at the end of the year
1,549 4,056

 

- -
1,549 4,056
5
57

Assets  

- -

 - -
Inventories
 - 

 - 

  

   

-  
 - 

- 
 - 


- -

 - -
Inventories
 - 

 - 

  

   

  
 - 

- 
 - 
Intangible assets


Patents,



 


   

- - - -

   

   

- - - -

-  

   

  

- - -

  

   

- -

 -

   

   
5
58


   

   

   

  

- - - -

-  

   

   

-   

  

   

- - - -

 -

  

   
- 
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
ctations for the
- 
ighting of the cost of


In  and
 There was no



Goodwill is specified 

 

 

 

 

 
5
59

 

 

 

 

 

 

en  

 

 


, 
Accounting policy
Goodwill

of the consideration


-

Patents, licenses and other intangible assets






-





e straight-line method over the esti-

-

Acquisition of entities

 sed at their fair val-

consideration arrange-






Research and development projects





which represent

ghts to the transfer of

5
60

reflected in the cost







 

Key accounting estimates and judgements
ement in relation to the identification of cash-
s
s

 


 asset 
tion


Tangible assets








ments
Assets

construc-
tion



    

- - - - -

  

    

- - - - -

   - -

    

    

- - - - -

    

    


- - - - -

- -

    

    

   

5
61

    

    


    

    

- - - - -

   - -

    

    

    

   

   


- - - - -

 -

    

    

   
Accounting policy

of self-





-

-

-

-





If an asset’s carrying







5
62
Leases

 


4
 

 


- -




    
Accounting policy

-of-


--of-


-of--line method over the

-of-

-


end the lease or
















the right
--of-


pensed on a straight
- 

Investment property
Accounting policy

and any directly asso-
 -
  million

5
63






an investment property are

missioning







DKK million
2025
2024







-
-
Cost at the end of the year
28,839
28,314

-
-


-

-
-
Value adjustments at the end of the year
-2,562
-2,849
Fair value at the end of the year
26,277
25,465



 

 

--







 













return in %

amount
-
  
-
  
Basis
 

 
5
64

 










- 
  

- 
  

- 
  

- 
  

- 
  

- 
  

- 
  

- 
  

- 
  



DKK





  

  
Business acquisitions
Business acquisitions in 2025

Novonesis
E


Genetics
 Tota

  

 
Inventories
  

 

  (

  

  
Non
-

  

  
  
5
65


  

  

  


  

 ) 

  
Business acquisitions in 2025 in Novo Nordisk
-finish sites remained provisional at

Business acquisitions in 2025 in Novonesis
-

-
Novonesis and dsm-
--
-



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 
ional handover and


-
right to sell and

from complementary
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
-
 with strong insights


-
-

 -

5
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

-

Business acquisitions in 2025 in Novo Holdings


 

About Benchmark
-
-

Strategic rationale and synergies
 chains that determine
 Mega trends -segments

hard-to-
Details of the acquisition



identified as the




•  which collec-

• -

•  

 


The contingent (earn-d
- 
 -
company’s estimat
5
67
Purchase price adjustments made in 2025 for prior acquisitions
Catalent
-finish sites from Novo Holdings A/S in connection with a transaction where Novo Hold-
h consideration transferred
  

2024
DKK million
Fill-finish sites
Other acquisi-
tions
Total
Provisional
Final
-how






















Other net assets




Net identifiable assets acquired
67,450
66,494
651
67,145
Goodwill




Purchase price
82,743
81,739
681
82,420



Settlement of pre-



Cash consideration transferred
82,146
82,146
681
82,827




Cash used for acquisition of businesses; net of cash acquired
81,482
81,482
681
82,163

  
  
-
  


  
highly---how and pro-

--
mented processes and systems for efficient and large--apacity in an efficient
-
--

Single Use Support
 for SinAthe goodwill re-
in the following
presentation:
5
68
DKK million
Before PPA
(31.12.2024)
Neutral
reclassification
After PPA
(01.01.2025)
Change 2025
As at
31.12.2025
Goodwill



-


-





-





-





-






-



Ellab

in an increase of  

DKK million
Provisional PPA
(31.12.2024)
Change 2025
Final PPA
(31.12.2025)

-




-



-



-


-





(5)
Net identifiable assets acquired
15
4
19
Goodwill



Purchase price
69
(1)
67
Business acquisitions in 2024



Novonesis
  

   

   

 

-  

  
Inventories
   

   

   

- - - -

- - - -

  - 

   
Non
- - - -

  - 

   
   
5
69


  

-  

 

 


   


  

- - - -

 -  
Catalent

-

About Catalent
 
--
-
 and technicians and the latest technology platforms
-enhancing and life-
Strategic rationale and synergies (post Novo Nordisk’s acquisition of three fill-finish sites)
nt has assisted in
-


hared mission of

Details of the acquisition (post Novo Nordisk’s acquisition of three fill-finish sites)

 recognition of a goodwill



--
Novo Nordisk’s acquisition of the three fill-finish sites from Novo Holdings A/S
Three fill-finish sites (Catalent)
-finish sites from Novo Holdings A/S in connection with a transaction where Novo Hold-
 fill-finish sites are special-



Strategic rational
5
70
-


Details of the acquisition
price allocation for
imited time to identify and deter-
-
cient and large---
--
--
place at the three fill-
-
ed additional net
se price allocation and

rt of the main
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Business acquisitions in 2024 in Novonesis
Novozymes A/S

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
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--
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-
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

Business acquisitions in 2024 in Novo Holdings


Single Use Support
5
71
e-

About Single Use Support
 and filtration
-and-- single-
Strategic rationale and synergies
-



Stingray Marine Solutions
fish health tech-

About Stingray Marine Solutions
--
-tim

Strategic Rationale
tion that en-


Accounting policy


the date when control was

red to former owners of the



ations are recognised in









certain at the date of



5
72
Key accounting estimates and judgements
f the identified
--


 


 --
-
-

d replacement cost


Associated companies

 
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   


  

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
 

- -



-

- 

- -

 -

-

- -

 



-


Accounting policy

associated compa-
nvestments in associated compa-

5
73
Financial assets

 

investments



assets


investments



assets

Investments

      


- - -

- -

 - 


    - -  -

      



       

 - - -

- -

-  -

-   -    

       

      



     

     

     

     

     

   

      



     

   

       
      




         

       

- - - - - -

    -   
5
74


- -  
       
Key accounting estimates and judgements
Life Science Investments and Securities
 
 preparation of the financial state-
al investments on
 portfolio o

Fair value estimation


 stment

e 
Hierarchy of fair value inputs

e following levels:
Level 1
Level 2

Level 3
 

 

 the investment is

Policy for determining when transfers between levels are deemed to have occurred

 
 
Valuation method and inputs
s




y follows the following hierarchy:



tion of a modelling

5
75
 


 

  maintaina-




:

   

  

  

  

   

 

  

   

  

   

 

   

:

   

  

  

  

   

 

  

   

  

   

 

   
-
t interest-






DKK



DKK


Income
-


 
5
76

-



 



-


 



N/A
 




 

Cost at recent transaction
N/A
 

 
the total Invest-














• N/A
• N/A

rect)


• Cost at recent transaction


• Cost at recent transaction


 
(
 










• N/A




• N/A
• N/A


– 



-

• Cost at recent transaction




• Cost at recent transaction








)


- 




• N/A





• N/A
• N/A


- 




• N/A



• N/A
• N/A
5
77




– 

• Cost at recent








– 




• N/A





• N/A
• N/A


Inventories

 

 

 

 

-- - -

 

-  



-  

- - -

- - -
Write
-  

 
Accounting policy


--




-down is rec-




-sed in the income statement as re-

-

5
78
Key accounting estimates and judgements
--




on costs for capi-


Trade receivables

 

 

- -

 


 

- -

 

- -

- -



 

 

-  

 

 
Accounting policy





Allowance for expected credit loss for trade receivables







forward
-
5
79
Other provisions
DKK million
2025
2024
Retirement

gations

for legal

Other
provisions
Total
Total












-

-
-
-

-
-
-
-
-


-
-
-





At the end of the year
1,435
3,687
3,594
8,716
9,699
Non-










At the end of the year
1,435
3,687
3,594
8,716
9,699
Provision for retirement benefit obligations

 


-
-
Provisions for legal disputes

Other provisions
 
-
Accounting policy
Provision for sales rebates








Provision for product returns
The Group issues credit notes for expired goods as a part of normal business. Where there is historical experience or a reaso
nably accurate esti-
mate of expected future returns can otherwise be made, a provision for estimated product returns is recorded. Th
e provision is measured at gross
sales value.
R
etirement benefit obligations

 





-

5
80

o other comprehen-

 

can 



-



cost trend rate and inflation are
ion (not considering plan




-
Provision for legal disputes

 of past events 




-

ncrease in the provision for interest is

Key accounting estimates and judgements
tes regarding provi-






Borrowings

 

 
-  

 

 
Non
-  

 

 

 


 
5
81

  

 

- 

 

 
Other liabilities

 -

Other non-cash items

 

 -

- 

- 

-  

 -

- - 
Cash and cash equivalents

 

 



 
Accounting policy





non
-cash items are reversed considered


-


--

vities in the cash flow state-






5
82
Derivative financial instruments

 
Contract


-



-




-

Contract


-


-




-




     

     
     


   

   

  
    



     

     
     

     

   

   


   

  
 T


Net investments 
 
ting as either hedges of fair


Accounting policy

Use of derivative financial instruments


5
83




Initial recognition and measurement

one of:
H

H
edges 


Fair value hedges



Cash flow hedges


ment of these contracts is transferred from other comprehensive income to the income statement when the hedged tra
nsaction is recognised in


-

Discontinuance of cash flow hedging

ve gain or loss



ately transferred to

Fair value determination










generally accepted

-
Commitments and contingent liabilities


 

 

 


 


5
84

 



 


 


 












on policy was con-

stent with 

 


r-
d ent
ling from the Seventh




cant reversal in the 

Pending litigation against Novo Nordisk






-



 
5
85



   



 

 
--

-


I Retirement Com-



-

-

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

-
--


Other provisions and contingent liabilities
 
-
th 
s; and the general demand for non-
-

-



Share-based payment schemes
-nesisellia -
  The share-pay-
ment schemes in Sonion-
5
86
-
-

--

Long-term share-based incentive programme
nesis and NNIT
There are schemes for management 

 

- 



 

- 

–-

 

- 

-


(RSU)  Novonesis A/S NNIT A/S
(RSU)  (RSU)
 

  

  

  

  


 



     


     


     

     

     

    -  
5
87
Accounting policy

--



of any non
--







Financial risks

 

nesis 









-


 

 






 

 

 

 

 

 5 ( 


- 

most -
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88
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
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agements of

een negotiated on
-
Subsidiaries with significant non-controlling interest

 Novonesis A/S - 
Non
-  


 

 

- -

 
Non
-   - ,

Non
-  

 
Non
-  

 
Non
-    


 
Non
-    


 

- -

- 
5
89

 Novonesis A/S - 
Non
-  


 

 

- 

 
Non
-   - 

Non
-  

 
Non
-  

 
Non
-    


 
Non
-    


 

- -

 -
Assets held for sale

 






 5
Accounting policy





ent losses arising on first clas-
sification as “held for sale” and gains and losses fro


Events after the reporting date
No events of importance to the consolidated financia 

Grants payable

 
5
90
Non
-












-





 
Group companies








A/S




























Novonesis A/S

















































5
91































































Associates































































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5
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
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
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Associates


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

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
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
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




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



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

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


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

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
5

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




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
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
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5

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5
93
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


































5
94










Croatia









































Greece






































Morocco
























Romania
















5
95

























r













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


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

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

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

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
Taiwan
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

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


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

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

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

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

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

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












Iran












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

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




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

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

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




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5
96





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

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
Vietnam
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



NNIT A/S












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









-




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

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


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

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

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

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

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

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

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

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

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

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

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

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
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

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
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
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

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

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

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

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5
97


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
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

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
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
Greece
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Greece
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
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
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
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
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
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Iran
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
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
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
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
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
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
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
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
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
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

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
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
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
Romania
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
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
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
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
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
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
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
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
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
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
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
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
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
-

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

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

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
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

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5
98

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
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
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
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
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
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

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

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

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

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
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

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

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
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
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

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
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



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

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

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5
99


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

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

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

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

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

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

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
Croatia
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

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

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

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

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
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

Sonion InvestCo A/S

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

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Sonion A/S

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

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

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
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
Vietnam
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
Vietnam
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

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



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
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
- 


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
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
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
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

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
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
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
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

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
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5
100
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

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

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
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
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
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
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

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


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

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
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

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
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
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
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
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
rica
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

rica
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
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
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
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5
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

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
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
- 


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
- 



NH Kronos Parent, Inc.
- 


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
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
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
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
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
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
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
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5
102
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
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
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
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
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



Novo Maia, LP
- 

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

- 

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

- 


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
- 

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
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
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
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






- 




- 




- 

































5
107
















- 







- 






5
108
Novo Nordisk Foundation
Risks related to societal responsibility
The primary associated with the 
 are
largely companies
  is-
related to the
granting activities are relatively small
managed adherence to 
and designed to promote responsi-
 and maintaining positive social role in society



ld scale and impact and cat-

dation’s corporate activities remain international in accordance with

Code of conduct, including anti-corruption and the whistle-
blower scheme



 









-à-
dation and 
 Read more at: https://novo-
-we-are/code-of-
 

Annex A (a part of Management’s Review)
Novo Nordisk Founda-
tion Group Corporate
Social Re
sponsibility



-awarding activities and then the corporate



5
109

https://novo-
-we-are/code-of-





affiliates and 
In thirteen reports via the whistle-

dedicated 
 Based on an 
 of the ethics and compliance program 
conflicts of
interestand data privacy and 
Economic and scientific responsibility
In 5 
thropic investments while its grant  








mpanies has preferential access to the

-giving






 



-impact
Social responsibility


this means strengthening research-



n-
tre


 





 and that people as






-
medical science grant-
In 5
 

 
 initiative 

-
for large-scale impl



st
--
tion’s mission on health is to “Progress research and innovation in the
prevention and management of cardiometabolic and infectious dis-
eases, regenerative medicine, and equitable health outcomes” and the

o Theme 1. Preventing and managing cardiometabolic diseases
o Ambition: Prevent and manage cardiometabolic dis-
eases through research-based action to reduce their
global burden
o Theme 2. Decreasing the burden and threat of infectious diseases
o Ambition: Support research into prevention, diagnosis,
and treatment of infectious diseases
o Theme 3. Advancing and applying regenerative medicine
o Ambition: Facilitate regenerative medicine solutions for
disease treatment and research advancement
o Theme 4. Reducing inequity in health
o Ambition: Reduce inequities in health with a focus on
people in vulnerable positions
Environmental responsibility

s

-
“Advance knowledge and solutions to support the green transition in
society”. 


5
110
• Theme 1. Sustainable and high yield agriculture:
o Ambition: Advance research and innovation in agricultural
production by understanding, controlling and utilising eco-
systems.
• Theme 2. Sustainable food for healthy diets:
o Support the transformation of our food systems towards
improved planetary and human health through research
and translation within sustainable production and
consumption.
• Theme 3. High-impact climate change mitigation technologies:
o Ambition: Eliminate greenhouse gas emissions from high-
carbon production and remove atmospheric CO
2
by
supporting and driving research for scalable climate
change mitigation technologies.
• Theme 4. Supporting society in the green transition:
o Ambition: Build knowledge, networks and systems to help
support the green transition in society.



nnovative

-year

 
 for pro-


 
55m
) in-

The
decreased from 

  
crease of  
5 increas 

ness travel (
B and C 

5
111
The commercial activities of the Foundation





and resolve to 
The criteria are:
• 

• – in technol-

• 

• 

• -
• 
• 
o financial performance
o environmental performance
o social performance
• 




-on--Ownership-of-Novo-
-
Based on the charter 



-
-

 


Risks in relation to societal responsibility

 


nde-

Companies in which Novo Holdings A/S has a controlling interest either report on



-the-



ncertainty with




invest-
ment approach and policy In 
es 
-
holdings--investment-report--delivering--
with-lasting-impact 



-holdings--- 
- and 
-report
Anti-corruption
Novo Holdings A/S
Novo Holdings A/S’ management approach to handling anti-


t define the way we


-of-

Novo Nordisk A/S

anti-





Reports 

Novonesis A/S
Novonesis A/S’ management approach to addressing anti-
Novo-
nesis 
tegrity-
5
112
Novonesis 

Novonesis’ 

Economic and scientific responsibility
Novo Holdings A/S
5 




5 
Novo Nordisk A/S

-

the end of

-

vestment in re-search and development incr eased

-


In  Commission’s  overview -
pository -  on the

 
Novonesis A/S
Novonesis A/S’ net sales in   

 A/S realized 
 In
  

Social responsibility
Novo Holdings A/S
Novo Holdings A/S  a 




in the Novo Holdings  is
 -investment--
By integrating societal impact and 

processes and engaged ownership activities
 deliver stronger financial re-


-



-

 As an ac-

ongoing monitoring of investment performance and portfolio com-

Novo Nordisk A/S


-term strategy

in 
to 


ards - 




-
maintaining short-


The  the OneCode policy and international and lo-

-
anti--off-
healthcare professionals 
and respect of 

 




Novonesis A/S



 




5
113


Novonesis is 

reaching net-
in the world to receive validation of its net-
nesis commits to reach net-
 Novonesis strives to de-




--positions
Health responsibility
Novo Nordisk A/S




-

-
tries and other low- and middle-

- and middle-income














-

-
-






-Sa-


nd im-

 









 Read more at 
Novonesis A/S









heir positive im-



 



Environmental and climate responsibility

Novo Nordisk A/S












-
p has an overarch-





5
114







estimated as water




rn (SVHCs) and







Novonesis A/S



-term and long-



tiative (SBTi)


-
 - an

Climate
Novo Holdings A/S

long-
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-
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 


SBTi-



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

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

-aligned opera-

-setting and

Novo Nordisk A/S

-
e emissions re-
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-
Corporate Net-m the Science Based Target initiative
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nd CO



– primarily renew-
-– ac-



Report: 

---report-
Novonesis A/S






science-
-reviewed life cycle


these data-


-zero emission company



5
115




In Novonesis reached its goal 
 


The Novo Group as a workplace








Novo Nordisk Foundation


terms of new employees and aThe
increased to  employ-




 of organisational attractiveness



5 
promotion gender gap analysis that showed that all promotions and


Novo Holdings A/S




5

Novo Nordisk A/S



ations regarding

-









aspiration for senior leadership was 

Novonesis A/S








striving for a mini-




Diversity policy in the Novo Nordisk Foundation
Group







nt and development processes in the







-
--
portal/principles-positions-and-policies/diversity--pol-

Novonesis A/S: --
policies
Diversity policy for the Novo Nordisk Foundation and Novo Holdings
A/S



5
116

 in some case The diversity
policy is an important part of the decision-


S were split into two de-


-



The 



- 






-policy/
By the end of 



which means that we at this level already now lives 

female and 
 
principles 

tion will in  



e have 

Diversity in Novo Holdings A/S
By the end of 
 and 
leadership level consists of  


diverse 
principles 
con-

T
able A. Gender diversity in the Novo Nordisk Foundation
     ()



      



      


    

      


    

      NA

--
Policy on data ethics





Novo Nordisk Foundation





117


cesses personal and non-
https://novo-
-ethics-and-ai-policy/





Novo Holdings A/S

-
-on-data-
Novo Nordisk A/S



adopted a set of principles for data and artificial intelligence (AI) ethics
-


 



-and--rights/data-eth-

Novonesis A/S
Novonesis 
the ethical management of data in Novonesis 

report 

Tab
le B: Sustainability indicators - Social footprints



Novonesis A/S

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
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
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
     
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


 

- 
/








/
/

- 




-
-
-
-
-
-
-
-
-
- 

/






/




- 













- 












-  








- 















-
-
-
-
-





 (
N/A


-














-
-
-







cations

   - - - N/A



 N/A





N/A


-
-
-







N/A


-
-
-
-
-
-
-
-
-

N/A


-
-
-
-
-
-
-
-
-

--
 A/S o 





A/S o

 

 
ions 

118
Tab
le C: Sustainability indicators - Environmental footprints

, )

, )

Novonesis A/S














/G)
)
     


 )
      
)

)







)




























services
           

-
-
-
-
-



-
-

activities
           


- - - - - -      

erations
       






















-
-
-
--

- - - - - - - - -


- - - - - -    - - -

ment

- - - -   - - - - - -














emission
   
       
,


     
Waste






































 







 

’


-



N A/S 





-



-


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Annual reportAuditor's report on audited financial statementsParsePort XBRL Converter2025-01-012025-12-312024-01-012024-12-312026-05-27Lars Rebien Sørensen529900UTAHSVRYZL0380Novo Nordisk FondenReporting class C, large enterprise10582989Tuborg Havnevej192900Helleruphttps://novonordiskfonden.dk/hvem-er-vi/code-of-conduct/https://novonordiskfonden.dk/app/uploads/Diversity-Policy.pdfhttps://novonordiskfonden.dk/en/data-ethics-and-ai-policy/https://novonordiskfonden.dk/en/who-we-are/recommendations-on-foundation-governance/https://novonordiskfonden.dk/app/uploads/Novo-Nordisk-Foundation-2024-Annual-Impact-Report.pdf2026-05-27529900UTAHSVRYZL038010582989Novo Nordisk FondenTuborg Havnevej 192900 HellerupOpinionBasis for Opinion2026-05-27mne2333133771231PricewaterhouseCoopers Statsautoriseret RevisionspartnerselskabStrandvejen442900Hellerupmne3220033771231PricewaterhouseCoopers Statsautoriseret 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