ALK-Abelló A/S
ge Allé 6-8, DK-2970 Hørsholm, Denmark,
CVR no. 63 71 79 16
Pioneers
of allergy
solutions
Annual report 2025
Contents
Introduction
5 Letter from the Chair and CEO
7 ALK's global presence
8 Business model
9 Financial highlights
10 Sustainability highlights
11 2026 outlook
Business strategy
12 Review of Allergy
+
implementation
18 Financial ambitions
Financial performance
19 Sales and market trends
21 Financial highlights and key
ratios for the ALK Group
22 Financial review
24 Q4 review
Corporate matters
25 Risk management
29 Corporate governance and ownership
33 Board of Directors
35 Executive Leadership Team
Consolidated financial statements
87 Income statement
87 Statement of comprehensive income
88 Cash flow statement
89 Balance sheet
90 Statement of changes in equity
91 Notes
125 Definitions
Parent company financial statements
127 Income statement
128 Balance sheet
129 Statement of changes in equity
130 Notes
Statements
137 Statement by Management
on the annual report
138 Independent Auditor’s Reports
141 Independent auditor’s limited assurance
report on the Sustainability Statement
Other information
1
143 Financial highlights and key ratios by
quarter for the ALK Group (unaudited)
Sustainability statement
1
Management's review Financial statements
1
Part of Management's review
General information
38 Basis for preparation
39 Sustainability governance
41 Stakeholder engagement
42 Materiality assessment process
43 Material impacts, risks and opportunities
Environmental information
44 Climate change
50 Pollution
51 Water
53 Biodiversity and ecosystems
54 Resource use and circular economy
56 EU Taxonomy
57 Accounting policies –
Environmental information
Social information
59 Own workforce
65 Workers in the value chain
67 Consumers and end-users
70 Accounting policies – Social information
Governance information
72 Business conduct
76 Accounting policies –
Governance information
Appendix
77 Incorporation by reference
78 Core elements of due diligence
78 Content index of ESRS
disclosure requirements
81 List of datapoints that derive
from other EU legislation
83 EU Taxonomy
Management's
review
Sustainability
statement
Financial
statements
Annual Report 2025 2
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www.alk.net
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About this report
This is ALK Abelló A/S’ (“ALK” or “the company”) integrated annual report for 2025, consisting of the two main
sections Management’s review including Sustainability statement and Financial statements.
Pioneers of allergy solutions
Pioneering in respiratory allergies for more than a
century, ALK has embarked on a mission to help more
people, with more solutions, more efficiently
Other 2025 reports
Remuneration report
Corporate Governance report
ALK markets a diversified portfolio of products, including allergy immunotherapy (AIT) tablets,
injections, and drops as well as adrenaline autoinjectors and nasal sprays.
ALKs therapy areas
Respiratory allergy
Disease-modifying treatment of
severe allergy (ALK's core business)
Anaphylaxis
Emergency treatment of severe
allergic reactions
Food allergy and
new disease areas
Novel treatments addressing high
unmet medical needs (in development)
Management's
review
Sustainability
statement
Financial
statements
Annual Report 2025 3
In 2025, ALK delivered above its original expectations with
strong commercial execution. Expanded reach to new
patient groups, launch of a broader product portfolio, and
new partnerships bolstered progress on ALK’s strategic
priorities and mission to help more people, with more
solutions, more efficiently.
Management's
review
Management's
review
IntroductionIntroduction
Business Business
strategystrategy
Financial Financial
performanceperformance
Corporate Corporate
mattersmatters
Sustainability
statement
Financial
statements
Annual Report 2025 4
2025 marked the seventh consecutive year of revenue and earn-
ings growth in ALK. Results clearly exceeded initial expectations
with revenue growing by 15% in local currencies and the EBIT
margin improving by 6 percentage points to 26%.
Delivering on our 25-in-25 EBIT margin target was a significant
milestone. We set this target in February 2021 on the back of the
2020 accounts which showed an EBIT margin of merely 4%.This
means that we have been growing the EBIT margin by more than
20 percentage points, while still allocating significant resources
to ongoing growth investments. This has only been possible
through careful prioritisation and resource allocation to high-im-
pact growth levers.
ALK now has a solid earnings platform and is well-positioned
to continue delivering stable, high organic growth while main-
taining an EBIT margin of around 25% in the coming years. As we
continue to upscale the company, ALK’s strong financial position
enables us to increasingly look at inorganic growth opportuni-
ties such as in-licensing and acquisitions, while also distributing
excess cash to shareholders.
Expanding patient bases
Progress in 2025 was driven by strong commercial execution
of particularly tablet and anaphylaxis sales across Europe and
North America. We expanded our prescriber and patient bases,
increasing the number of people treated with ALK’s products by
500,000 to an estimated 3.1 million.
The recalibration of ALK’s business platform allowed us to pursue
priorities in the Allergy
+
strategy more rigorously. Key actions
included strengthening the footprint in high-growth markets and
putting more weight behind the launches of paediatric tablets and
the nasal adrenaline spray
neffy
®
, while also improving earnings.
Children make a difference
The paediatric approvals of ACARIZAX
®
and ITULAZAX
®
added
to the tablets’ strong momentum suggesting that children and
adolescents will become important catalysts for ALK’s future
growth. As expected, contribution from the adrenaline nasal
spray
neffy
®
was modest, reflecting the early stage of the
roll-out, but the feedback from key opinion leaders, healthcare
professionals, and patients indicates high interest, supporting
the many market introductions in 2026.
Our European business continued to deliver solid, double-digit
growth, and the US business made a comeback after the soft
performance in 2024. US tablet sales continued to grow by double
digits, and we are still working to find new ways to overcome long-
standing structural barriers among allergists who have a financial
incentive to protect their legacy business. Our global partnership
with ARS Pharma – the company that developed
neffy
®
– showed
progress in its first year and further enabled ALK to accelerate
the build-up of a dedicated paediatric sales force in the USA.
While focus initially has been on
neffy
®
, the extended sales reach
is expected to benefit US sales of respiratory tablets and future
prescription-based products, including potentially a tablet for
peanut allergy currently in development.
Partnering for growth
Partnerships are a central element in the Allergy
+
strategy. In
2025, we enjoyed good progress with existing partnerships and
entered new ones.
In China, we partnered with the biopharmaceutical company
GenSci to fast-track sales of ALK’s products in this important,
yet complex market. GenSci was an obvious choice given their
capacity of expanding product portfolios, their commitment to
deploy significant resources to succeed with ALK’s products, and
their understanding of the paediatric field. GenSci has already
started selling our Alutard SCIT product and diagnostics, and
we collaborate closely to bring the ACARIZAX
®
tablet to market
for both adults and children. ALK and GenSci will also explore
possible future collaborations on innovations as there are many
innovation efforts targeting new medicines in China, also within
GenSci. To stay close to these opportunities, we have maintained
Letter from
the Chair and CEO
ALK delivered on its long-term financial
targets in 2025 following strong execution of
strategic initiatives across disease areas.
Based on the strong momentum and the
solid financial position, the Board of Directors
recommends resuming dividend payments to
reward the shareholders directly.
Peter Halling,
President & CEO
Anders Hedegaard,
Chair of the Board
Management's
review
IntroductionIntroduction
Letter from Letter from
the Chair and CEOthe Chair and CEO
ALK's global ALK's global
presencepresence
Business modelBusiness model
Financial highlightsFinancial highlights
Sustainability Sustainability
highlightshighlights
2026 outlook2026 outlook
Business Business
strategystrategy
Financial Financial
performanceperformance
Corporate Corporate
mattersmatters
Sustainability
statement
Financial
statements
Annual Report 2025Letter from the Chair and CEO 5
Introduction
a local team, while more than 95% of our employees in China were
transferred to GenSci.
In Japan, a new facility has become fully operational, significantly
increasing the production capacity of cedar tablets and we are
experiencing a strong commitment towards our products from
Shionogi, the new owner of Torii. The performance in Japan and
– on a smaller scale – other international markets proves that
partnerships are an excellent way to develop markets, seed oppor-
tunities, and establish leading positions for ALK’s tablets without
investing in resource-intensive local organisations and registration
trials.
We have the right setup to further progress with partners in
selected markets. This approach allows us to allocate ALK’s
investments to the strategic levers expected to yield the highest
returns for the company – i.e. high-growth markets in Europe and
North America, in-house R&D, in-licensing, and M&A – and still
maintain a 25% EBIT margin.
Strengthening innovation and pipeline
In line with ALK’s revenue growth, we continue to increase invest-
ments in R&D and activities to develop a balanced pipeline and
drive innovations in existing and adjacent disease areas to expand
ALK’s addressable markets. The ambition within each therapy
area is to push the frontiers of innovation and build product port-
folios with the potential to establish ALK as market leader and help
more patients. We aim to generate significant revenue streams to
complement ALKs current core business within respiratory allergy.
Besides targeting significant unmet needs, new products must be
strongly linked to ALKs current product portfolio and prescribers.
To balance investments, risks, and in alignment with our Allergy
+
strategy, we combine in-house development with partnerships
on early-stage product candidates and commercial assets, such
as
neffy
®
. Late 2025, we partnered with the Swiss-based biotech
company Allegria, and ALK will continue to explore other partner
opportunities.
Important data read-outs are expected in 2026 from the two most
advanced development programmes – ALK’s phase 2 trial with the
tablet for treating peanut allergy and our partner ARS Pharma’s
phase 2b trial with
neffy
®
for treatment of acute flares associated
with chronic spontaneous urticaria. We also expect to progress
pre-clinical programmes towards clinical development in 2026.
Shareholder remuneration
ALK enters 2026 with a comfortable net cash position and pros-
pects of strong cash flows in the years to come. This leaves ample
room for continued, value-creating capital allocation to sustain
ALKs growth, while also remunerating our shareholders.
The Board of Directors recommends distributing around 30% of net
profit after tax for 2025 as dividends, corresponding to a distribu-
tion of DKK 355 million or DKK 1.6 per share.
Progress to continue in 2026
Commercial execution also tops the agenda for 2026. The roll-out
of paediatric tablets continues to expand prescription breadth
and depth in existing markets, while also launching in additional
markets. Within anaphylaxis, we are dedicated to making
neffy
®
a success and working carefully across markets to change habits
and automated prescription patterns to build the market position
that
neffy
®
deserves.
We will also execute on other strategic priorities in 2026. We
continue to invest in expanding European prescriber bases,
strengthening the commercial platform in key growth markets,
advancing strategic R&D projects, and upscaling tablet produc-
tion capacity to facilitate sustained growth. These efforts will be
supported by recent changes in the Executive Leadership Team
which has been expanded to include ALK’s two most important
sales regions, Europe and North America.
Scaling ALK for future growth is another priority which entails
ongoing investments in digitalisation and AI, upskilling of
employees, as well as initiatives to achieve economies of scale,
for instance in procurement. We are equally committed to our
sustainability goals. ALK decreased its CO
2
emissions from own
operations by 11% compared to 2022, despite the significant
growth of the business. This is in line with the decarbonisation
plans supporting ALK’s science-based target to reduce CO
2
emissions by 42% by 2030.
We expect strategic execution to reinforce ALK’s growth trajec-
tory in 2026. The outlook sustains the double-digit growth
momentum, as revenue is expected to grow by 11-15% with tablet
sales as the key driver. The EBIT margin is expected at around
25%, fully aligned with ALK’s long-term targets. Continuing the
positive momentum from 2025 into 2026 will support further
progress of the Allergy
+
execution and bring ALK one step closer
to our goal of annually helping 5 million people with allergy live
better lives by 2030.
Strong commitment from employees
As Board of Directors and executive management, we are pleased
to see that performance and execution have become part of
ALK’s culture – of the way we think and act. The annual engage-
ment survey among employees highlighted progress across key
domains, and the overall engagement score’s increase from 8.3 to
8.6 strengthened ALK’s position in top 5% of the global healthcare
industry. We would like to thank our employees and leaders for
their ongoing commitment to executing on the Allergy
+
strategy.
We also wish to thank our commercial and scientific partners,
whose collaboration is part of our success, as well as the
growing number of payers, patients and prescribers who place
their trust in our products. Finally, we would like to thank our
shareholders. As ALK’s performance continues to improve, we
look forward to rewarding our owners through sustained, long-
term value creation.
Anders Hedegaard Peter Halling
Chair of the Board President & CEO
Management's
review
Introduction
Letter from
the Chair and CEO
ALK's global
presence
Business model
Financial highlights
Sustainability
highlights
2026 outlook
Business
strategy
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Letter from the Chair and CEO 6
ALK's global presence
~3.1m
Patients in treatment with ALK products
(Covering AIT and adrenaline)
6,312m
Revenue, DKK
Europe: 71%
North America: 16%
International markets: 13%
2,711
Employees
Eu r o p e: 2,161
North America: 533
International markets: 17
Production sites in
Europe
and USA
R&D centres in
USA, Denmark,
and Spain
Own commercial footprint
Partnerships and
distributors
44 markets covered
Strategic partnerships
GenSci
Mainland China
Shionogi
Japan
Dr. Reddy's
India
Abbott
Selected markets in
Southeast Asia
ARS Pharma
Global rights to
neffy
®
(excluding
USA, China, Japan, Australia, and
New Zealand)
Management's
review
Introduction
Letter from
the Chair and CEO
ALK's global
presence
Business model
Financial highlights
Sustainability
highlights
2026 outlook
Business
strategy
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025ALK's global presence 7
IPR and
discovery
Process
innovations and
formulations
Clinical
trials
Regulatory
processes
Resources
+10 0 yea r s profound under-
standing of the biology of the
allergic disease
500,000
additional patients treated
in 2025, bringing the total
number to 3.1 million
~420 million
AIT doses produced
(excluding ALK's SCIT bulk
extracts in the USA)
~48%
global market
share in AIT
~2,70 0 employees with
diverse talents
Insights from academia,
patients and partners
Raw materials,
energy, water, etc.
Digital engagement
platforms
Financial resources
Safety, quality, and business ethics compliance
2025 results
Business model
ALK's business model is based on
immunology insights, strong research
and development skills, commitment to
applying modern science to allergies,
unique manufacturing and standardisation
capabilities, as well as a comprehensive
commercial infrastructure, especially in
Europe.
ALK's activities cover the entire value chain of developing,
sourcing, producing, and marketing a diversified portfolio
of products for diagnosing and treating allergies, allergic
asthma, and acute anaphylactic reactions. Natural aller-
genic source materials are the basis for manufacturing
active pharmaceutical ingredients in ALK's core allergy
immunotherapy (AIT) products.
Business and
value chain
1
Externally sourced products
Distribution and sales
ALK present
in 44 markets
Selected
markets
served by
partners
Global
distribution
Digital patient
mobilisation
1
ESRS 2-SBM1-42(a,b,c)
Research & development
Manufacturing
Standardise
allergen
extracts
Production
at 9 sites
Cultivate
allergenic source
materials
Research expertise in
molecular and clinical
allergology
Proven clinical development
competencies
Management's
review
Introduction
Letter from
the Chair and CEO
ALK's global
presence
Business model
Financial highlights
Sustainability
highlights
2026 outlook
Business
strategy
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Business model 8
15%
Financial highlights
ALKs full-year revenue grew by 15% in local currencies to DKK 6,312
million (5,537), following double digit growth in all sales regions.
Operating profit (EBIT) increased by 53% in local currencies to DKK
1,654 million (1,091). The outlook was adjusted upwards twice
during 2025.
Revenue, DKK
6,312 million
15% organic growth in local
currencies, in line with
latest guidance
Gross profit, DKK
4,234 million
67% gross margin, driven by
higher sales, efficiencies, and
favourable product mix
Free cash flow, DKK
1,432 million
Strong cash flow driven by
higher earnings
Net interest-bearing debt (NIBD), DKK
-822 million
Positive net cash position from
strong cash flow generation
3,916
292
4,824
666
4, 511
470
5,537
1,091
6,312
1,654
2024 20242021 20212025 20252022 20222023 2023
2,396
202
516
61%
1.0
3,035
292
291
63%
0.3
2,791
65
475
62%
0.7
3,552
-204
598
64%
0.4
4,234
1,432
-822
67%
-0.4
2024 2024 20242021 2021 20212025 2025 20252022 2022 20222023 2023 2023
12%
7%
9%
14%
13%
10%
15%
20%
26%
Revenue
Organic growth
EBIT
EBIT margin
Gross profit
Gross profit margin Free cash flow
NIBD
NIBD/EBITDA
Earnings (EBIT), DKK
1,654 million
26% EBIT margin, in line
with latest guidance
Management's
review
Introduction
Letter from
the Chair and CEO
ALK's global
presence
Business model
Financial highlights
Sustainability
highlights
2026 outlook
Business
strategy
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Financial highlights 9
Sustainability highlights
ALK aspires to annually help 5 million people
living with allergy by 2030
1
Scope 1 and 2 emissions, CO
2
e
4,883 tonnes CO
2
e
11% decrease compared
to 2022
Patients in treatment
~3.1 million
Net increase of 500,000 patients
Employee headcount
2,711 employees
12% employee turnover
Suppliers with science-based targets, %
50%
share of suppliers with
science-based targets.
Target: 80% by 2028
Gender diversity, %
38%
Underrepresented gender
in Executive Leadership
Team and direct reports in
management positions
Target: 40% by 2028
Work-related accidents with absence
4
1.0 lost time injury
frequency rate
Employee headcount
Employee turnover
Carbon emissions
Development compared
to 2022
Million patients in treat-
ment (estimated)
Work-related accidents
with absence
Lost time injury
frequency rate
Underrepresented
gender (f)
Suppliers with science-
based targets
2,889
42
3
12%
0.8
2,731
42
6
13%
1.7
2,812
45 6
17%
1.5
2,711
38
4
12%
1.0
2024 2024 2024
35
50
2024 2025 2025 2025 20252022
2
2022
2
2022
2
2023
2
2023
2
2023
2
2.4
5,492
2.6
5,384
2.4
5,7093.1
4,883
5.0
3,18 5
2024 20242028 20282025 20252029 20292030 20302022
2
20222026 20262023
2
2023
2
2027 2027
0%
-2%
4%
-11%
-42%
1
ESRS 2-SBM1-40e
2
2022 and 2023 figures are not covered by the Independent Auditor’s limited assurance report.
Management's
review
Introduction
Letter from
the Chair and CEO
ALK's global
presence
Business model
Financial highlights
Sustainability
highlights
2026 outlook
Business
strategy
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Sustainability highlights 10
(Revenue growth rates are stated as organic
growth in local currencies, unless otherwise
indicated)
Revenue is expected to grow by 11-15% organ-
ically in local currencies, based on growth
across all sales regions and product groups.
The EBIT margin is expected at around 25%,
consistent with ALK’s long-term earnings ambi-
tions, as additional funds will be allocated to
initiatives to bolster long-term growth.
The outlook is based on the following main
assumptions:
Revenue
Growth will predominantly be volume-driven,
as ALK expects to treat more patients with AIT
and anaphylaxis products. The lower end of
the revenue range reflects a potential negative
impact of price and rebate adjustments, mainly
driven by European authorities. The upper end
of the range assumes stable price and rebate
conditions as well as potential upsides related
to tablet and anaphylaxis sales.
Tablet sales are expected to grow by double
digits across sales regions. Growth will
be fuelled by the continued expansion of
prescriber and patient bases with children and
adolescents projected to account for a higher
share of sales.
SCIT/SLIT drops sales are projected to grow by
single digits, driven by higher SCIT volumes to
China, modest volume growth in Europe (SCIT
and SLIT drops), and improved SCIT pricing in
North America.
Sales of Anaphylaxis & other products are
projected to grow by double digits, led by the
commercialisation of
neffy
®
. Sales of diag-
nostics and life science products are also
expected to contribute positively.
As usual, the timing of product shipments to
China and Japan may lead to quarterly fluctua-
tions in revenue.
Margins and costs
After the extraordinary margin improve-
ments in 2025, the gross margin is expected
to decrease slightly in 2026, although the
gross profit is expected to increase. The
underlying margin will benefit from favour-
able volume/mix changes, especially higher
tablet sales in Europe, but this factor will be
offset by growth in partner-related revenue
at lower margins, primarily product ship-
ments to Japan and China, as well as
neffy
®
sales. Production efficiencies, reduced
scrapping, and procurement savings are
expected to largely compensate for infla-
tionary pressure on the gross margin.
Capacity costs are projected to increase
but their ratio to revenue is expected to
remain largely unchanged as ALK reinvests
the benefits of increased scale into key stra-
tegic growth opportunities. R&D expenses
are planned to increase in support of
pre-clinical and clinical programmes but
remain at around 10% of revenue. Sales
and marketing expenses are expected
to increase in support of market-building
activities for particularly
neffy
®
and tablets
for children, while administrative expenses
are planned to decrease slightly.
2026 outlook
ALK expects to continue its
trajectory of double-digit revenue
growth in 2026, while the EBIT
margin is planned to remain on
par with ALKs long-term earnings
ambitions.
Forward-looking statements
The report contains forward-looking statements, including forecasts of future revenue, operating profit, and cash flows as well as expected business-related events. Such statements are subject to risks and uncertainties, as various
factors, some of which are outside ALK's control, may cause actual results and performance to differ materially from the forecasts made. Such factors include, but are not limited to, consequences of pandemics, general economic and
business-related conditions including legal issues, uncertainty relating to demand, pricing, reimbursement rules, partners’ plans and forecasts, fluctuations in exchange rates, competitive factors, reliance on suppliers, and tariffs.
Additional factors include the risks associated with the sourcing and manufacturing of ALK’s products, as well as the potential for side effects from the use of ALK’s products, as allergy immunotherapy may be associated with allergic
reactions of differing extent, duration, and severity. Please refer to the Risk management section on pages 25-28.
Other assumptions
The outlook is based on ALK’s current
portfolio and does not include revenue from
and/or payments to new partnerships,
in-licensing activities, or acquisitions.
Potential changes to international tariff
agreements are not expected to materially
impact growth or earnings due to ALKs
current geographical footprint.
Free cash flow is expected to be positive
at DKK 800-1,000 million representing a
decrease compared to last year, partly due
to the upfront payment from ALK’s Chinese
partner GenSci in 2025. CAPEX is projected
at around DKK 500 million, as ALK expands
capacity for tablet production, upgrades
legacy production, and strengthens the
supply chain for anaphylaxis. The build-up
of inventories is broadly assumed in line
with revenue growth. Tax payments are
expected to be higher than in 2025 as old
tax losses now have been utilised.
No non-recurring costs for optimisation
and prioritisation initiatives are planned.
The outlook is based on current exchange
rates, resulting in a negative impact of
approximately 1 percentage point on
reported revenue growth and an immate-
rial impact on EBIT.
Management's
review
Introduction
Letter from
the Chair and CEO
ALK's global
presence
Business model
Financial highlights
Sustainability
highlights
2026 outlook
Business
strategy
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 20252026 outlook 11
Respiratory
allergy
Food allergy
New disease
areas
Anaphylaxis
Review of Allergy
+
implementation
Strategic progress in 2025 reflected solid execution
across all disease areas with particular focus on
paediatric tablet launches, the commercialisation of
neffy
®
, new partnerships, and strategic R&D projects.
ALKs long-term ambition is to become category leader
in each disease area via in-house R&D development,
partnerships and in-licensing activities, and thereby
build new revenue streams to complement the current
core business within respiratory allergy.
Respiratory allergy
Launches of house dust
mite (HDM) and tree pollen
allergy tablets for children
and adolescents
Expansion of patient and
prescriber bases
Partnership to accelerate
Chinese AIT sales
Geographic expansion in
selected markets, incl.
registration trials in partner
markets
ALK’s HDM and tree pollen
tablets recommended by
NICE for use in the UK health
system
Food allergy and new disease areas
Phase 2 clinical trial with peanut
SLIT-tablet initiated
Fast track designation to peanut
SLIT tablet programme by FDA
Pre-clinical development
programmes targeting tree nut
and other food allergy indications,
including the ALK014 programme
with a new antibody like-molecule
(biologic) for the treatment of allergy
and associated co-morbidities.
Phase 2b clinical trial with
neffy
®
in the treatment of acute flares in
patients with chronic spontaneous
urticaria (CSU)initiated
Anaphylaxis
Initial roll-out of
neffy
®
nasal adrenaline spray
with price premium relative
to autoinjectors
EUR
neffy
®
reached market
share of close to 18% in
Germany after 6 months
EUR
neffy
®
approved in UK
and launch in progress
Ongoing regulatory review
of
neffy
®
in Canada
EUR
neffy
®
market access
settled in other markets
with imminent launches
Co-promotion agreement
with ARS Pharma in the USA
In 2025, ALK took steps to expand its addressable
markets by further unlocking the potential within
respiratory allergy, transforming anaphylaxis care, and
expanding into new therapy areas with high unmet needs.
Strategic focus was particularly on market expansion,
partnerships, innovation, scalability, and capacity
build-up. The execution of the Allergy
+
strategy delivered
the anticipated results, supported by a re-allocation
of resources to initiatives with the highest potential to
impact patients and prescribers positively, while also
generating the highest returns for ALK.
An estimated 3.1 million people, an increase of 500,000,
were treated with ALK’s products. The increase was
mainly organically driven by more patients treated with
ALK's tablets. This is an important step forward towards
the ambition of annually helping 5 million people with
allergy live better lives by 2030.
Key Allergy
+
progress in 2025
Management's
review
IntroductionIntroduction
Business Business
strategystrategy
Review of AllergyReview of Allergy
++
implementationimplementation
Financial ambitionsFinancial ambitions
Financial Financial
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Corporate Corporate
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Annual Report 2025Review of Allergy+ implementation 12
Business strategy
Roll-out of paediatric tablets
The paediatric roll-out of the house dust mite
(HDM) tablet ACARIZAX
®
/ODACTRA
®
began in
Europe in January and progressed market by
market, following subsequent approvals and
market access processes. Year-end, the house
dust mite tablet was approved for paediatric
use in 30 countries and launched in 21 of them
– 10 EU member states, Norway, Switzerland,
Canada, the USA, and seven partner markets.
The roll-out of the tree pollen allergy tablet
ITULAZAX
®
/ITULATEK
®
for children and adoles-
cents started in April, based on regulatory
approvals from the EU and Canada. Year-end,
the tablet was approved for children and
adolescent use in 20 countries and launched
in 12 of these markets – 10 EU member states,
Switzerland, and Canada.
Respiratory allergy
In 2025, ALK expanded its leadership in respiratory
allergy through targeted expansion of the tablets
to new patient groups and geographies, digital
mobilisation of patients and prescribers, and
investments in high-impact markets. The new
paediatric indications for the house dust mite (HDM)
allergy tablet and the tree pollen allergy tablet
contributed more than expected to sales growth.
Children make a difference
All key indicators related to the paediatric
launches performed well, including endorse-
ments from key opinion leaders, patient
initiations, caregiver interactions, doctor
visits, reimbursement, and prescriber uptake.
Year-end, more than 4,000 prescribers in
markets served directly by ALK were estimated
to have prescribed one of the two tablets to
children. Cross-tablet adoption was high, with
more than 90% of ITULAZAX
®
prescribers in key
European markets also prescribing ACARIZAX
®
.
In the key German market, paediatrician
doctors emerged as an important prescriber
group. This group included doctors who have
previously not been prescribing ALK's tablets,
underlining the tablets’ potential to expand
ALK’s addressable markets. Positive signs of a
Allergy
+
strategy
Launched in June 2024, the Allergy
+
strategy sets the framework and goals
for ALK’s development until 2028. The
strategy builds on ALK’s promise to
provide life-changing solutions to the
millions of people with allergy. The
strategy is based on four pillars:
Focus – Innovate – Optimise – Cultivate.
FOCUS ALK will prioritise and focus the
commercial activities to strengthen its
global leadership in respiratory allergy.
INNOVATE ALK will innovate and expand
its R&D pipeline in a balanced way to
help more people with allergy.
Innovate
We will inno-
vate to create
a balanced
pipeline
Cultivate
We will
cultivate
our unique
capabilities
to stay ahead
and to grow
sustainably
Focus
We will grow by focusing on
new patient groups and
high-impact markets
Optimise
We will optimise to create
the right foundation
for scaling
Life-changing
allergy solutions
for millions of
people
OPTIMISE ALK will further optimise oper-
ations and scale for growth to reduce
complexity and maintain competitiveness.
CULTIVATE ALK will cultivate the capa-
bilities of its people and organisation to
foster a strong performance culture.
Management's
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Business
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Review of Allergy
+
implementation
Financial ambitions
Financial
performance
Corporate
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statement
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statements
Annual Report 2025Review of Allergy+ implementation 13
portfolio effect also emerged, as children and
adolescents accounted for an increasing share
of new GRAZAX
®
patients in e.g. Germany.
The paediatric tablet roll-out continues in 2026
to further increase children and adolescents’
share of sales. Besides expanding prescription
breadth and depth in current markets, ALK is
also planning to launch the tablets in additional
markets.
Expanding the tablets’ reach
Beyond paediatric roll-outs, ALK and its part-
ners continued to expand the tablet portfolio’s
reach in selected geographies.
ALK’s Japanese partner Torii (now a fully
owned subsidiary of Shionogi) initiated a
phase 3 trial with ALK’s grass tablet. Sched-
uled to complete in 2027, the trial is intended to
support a regulatory approval in Japan, which
is the largest contributor to tablet sales outside
Europe. Moreover, Torii expanded API produc-
tion capacity for CEDARCURE™, the tablet for
Japanese cedar pollen-induced allergy. The
new facility has recently become operational,
with first shipments anticipated in the first half
of 2026, allowing Torii to incrementally meet
the high demand for CEDARCURE™ in 2026.
In India, ALK’s partner Dr. Reddy’s Laboratories
launched the HDM tablet branded Sensimune
®
.
Expanding footprints in
the USA and the UK
In the USA, a dedicated paediatric sales
force (see ‘Anaphylaxis’ section) is expected
to boost ALK’s relevance among paediatric
prescribers who historically have not been
involved in AIT. The extended sales force is
expected to support sales of ALK’s respiratory
tablets and a future peanut allergy tablet.
ALK is also exploring other steps to grow its
prescription-based business in the USA.
In the UK, ACARIZAX
®
and ITULAZAX
®
were the
first AIT tablets to be admitted to the public
National Health Service (NHS) systems with
general reimbursement after endorsements
from the National Institute for Health and Care
Excellence. This represents a major shift in
this historically underpenetrated AIT market.
Furthermore, ALK is in the process of extending
these approvals to include children while also
making GRAZAX
®
available in the NHS systems.
New partner to expand
market in China
In China, ALK partnered with Changchun
GeneScience Pharmaceutical Co. Ltd.
(“GenSci”) to accelerate sales of ALK’s HDM
products in the country with the highest
number of house dust mite allergy sufferers
world-wide. GenSci plans to allocate a signif-
icant sales force and conduct a wide range
of market building activities to promote ALK’s
products and become AIT market leader.
GenSci has taken over sales and marketing
of ALK’s Alutard
®
SCIT product and skin prick
tests, and ACARIZAX
®
will expectedly be added
to the portfolio in 2028, subject to regulatory
approval. To facilitate this approval, a phase
3 trial involving around 300 Chinese patients
is ongoing with completion scheduled around
year-end 2026. Patient recruitment for the trial
is currently being completed.
ALK received DKK 244 million in upfront
payment from GenSci. Until 2039 (the expected
lifetime of the partnership), ALK is further
eligible for DKK ~300 million in milestone
payments related to regulatory progress
with ACARIZAX
®
and commercial milestone
payments of up to DKK ~780 million, subject
to future in-market sales in Mainland China.
Furthermore, ALK will receive income from
supplying GenSci with products.
Management's
review
Introduction
Business
strategy
Review of Allergy
+
implementation
Financial ambitions
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Review of Allergy+ implementation 14
ALK’s roll-out initially focused on Germany and
the UK, the markets expected to become the
most important contributors to
neffy
®
sales
growth.
EUR
neffy
®
was launched In Germany late June
and had gained a market share of close to 18%
(by value) by the end of the year. The launch
in the UK followed in October and attracted
significant interest from healthcare profes-
sionals, key opinion leaders, and media. Given
the early stage of the UK launch, the commer-
cial impact was modest, reflecting the time
needed to settle market access locally.
neffy
®
is currently under regulatory review in Canada
and the outcome of this process is expected in
the first half of 2026.
By the end of the year, EUR
neffy
®
market
access was also settled in Greece, Denmark,
and Slovenia and launches are imminent.
Ongoing price negotiations
In markets, where pricing and reimbursement
have been settled, EUR
neffy
®
has secured a
price premium over existing adrenaline auto-
Anaphylaxis
In 2025, ALK started launching the first-ever nasal adrenaline spray
neffy
®
(branded EUR
neffy
®
in Europe) for emergency treatment of
potentially life-threatening allergic reactions (anaphylaxis). Under a
license agreement with US-based ARS Pharma, ALK holds exclusive
rights to the product in all territories outside the USA, Australia,
New Zealand, Japan, and China.
injectors, reflecting the nasal spray’s benefits
with regards to shelf life, temperature stability,
user-friendliness, and needle-free adminis-
tration. In 2025, the first real-world evidence
confirmed that its efficacy during anaphy-
laxis is similar to what historically has been
observed with injection-based solutions.
Co-promotion agreement in the USA
In the USA, ALK and ARS Pharma expanded
their partnership with a co-promotion agree-
ment where ALK is responsible for selling
neffy
®
to approximately 9,000 named paedi-
atricians. This has enabled ALK to accelerate
ramp-up of a dedicated paediatric sales
force with 65 sales representatives, based on
performance-based cost and revenue sharing
with ARS Pharma, subject to sales exceeding
certain market share thresholds among the
paediatricians.
Although market access conditions did not
meet the targets, customer engagement and
other KPIs for ALK’s efforts largely developed
as planned, and feedback from paediatricians
has been positive.
Ongoing roll-out in 2026
Further launches of
neffy
®
are scheduled for
2026. Subject to regulatory approvals and
market access, the current roadmap involves
launches in Canada and up to 15 European
markets covered by the EU approval as well as
countries outside the EU. ALK also intends to
make
neffy
®
available in International markets.
Across markets, ALK will work with key opinion
leaders and others to challenge long-standing
clinical practices favouring needle-based
adrenaline products.
To accommodate different preferences among
prescribers and patients, ALK will address
the anaphylaxis market with a portfolio span-
ning both needle-free solutions (
neffy
®
) and
autoinjectors (the already marketed Jext
®
and
the second generation ‘Genesis’ autoinjector
currently in development). The portfolio will
be adapted to evolving market dynamics to
secure a strong position in patient-centric
anaphylaxis care.
EUR
neffy
®
2 mg is currently indicated for adults
and children ≥30 kg. Recently, ALK received a
positive recommendation from the European
authorities regarding its application for a 1 mg
version for children aged 4 and older weighing
15 to 30 kg with approvals anticipated in the
first half of 2026.
Management's
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Business
strategy
Review of Allergy
+
implementation
Financial ambitions
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Review of Allergy+ implementation 15
Ongoing phase 2 clinical trials
The phase 2 trial for dose finding and efficacy
of the peanut SLIT tablet enrolled 150 North
American patients and is on track to deliver
topline data in the second quarter of 2026.
Subject to these results, ALK plans to progress
into phase 3, and preparations are ongoing,
including selection of Contract Research
Organisations and manufacturing of source
material. The US FDA has granted a Fast
Track designation to the peanut programme,
enabling ALK to benefit from more frequent
interactions and additional guidance from the
FDA.
ALK’s partner ARS Pharma initiated a phase 2b
clinical trial with patients in the USA and Europe
to evaluate
neffy
®
in the treatment of acute
flares associated with chronic spontaneous
urticaria. First read-outs from this trial are
expected in 2026. ALK holds exclusive rights to
this and any other new indications for
neffy
®
in
the licensed territories.
New discovery and innovation
Building on ALK’s core capabilities within
clinical allergology and immunology, in-house
development focusses on allergic inflam-
matory conditions and so-called mast cell
driven pathologies. Pre-clinical development
programmes include a SLIT tablet for tree nut
allergy and the biological treatment concept
ALK014, which is potentially applicable for both
food allergy and other diseases.
In late 2025, to complement internal discovery
programmes, ALK partnered with Allegria
Therapeutics, a Swiss early-stage biotech
company focusing on allergy and inflammatory
diseases associated with mast cell dysfunc-
tion. Against a seed investment, ALK secured
the rights to negotiate in-licensing of up to
three first-in-class disease targets.
ALK and Chinese GenSci also intend to explore
innovations of common interest, based on a
reciprocal right of first negotiation for R&D
projects.
Moreover, based on a thorough screening of
external pipeline opportunities and commer-
cial assets, ALK is exploring other partnership
opportunities, including in-licensing, acquisi-
tions and/or joint development projects.
Food allergy and new therapy areas
In the wider allergy space, innovation targets new therapy areas with
significant unmet needs as well as strong scientific and commercial links
to ALKs current portfolio and prescribers. In 2025, clinical phase 2 trials
were initiated with the two most advanced product candidates.
ALK is investing in supply chain expansions and
optimisations to support margins and facilitate
planned revenue growth. A key initiative in
this respect is the ongoing efforts to increase
tablet production capacity to 800 million
units per year by 2030 within the existing
footprint, optimise inventory management,
minimise scrap, and reduce delivery times,
all while maintaining compliance and quality
standards. Legacy production is also being
upgraded, while the supply chain for anaphy-
laxis is being strengthened through insourcing
of certain tasks.
Scaling the business for growth
ALKs growth ambitions across therapy areas is supported by
efforts to scale the business and realise economies of scale.
Strengthening of procurement and IT processes and capabilities
to exploit economies of scale and streamline the supplier
landscape continue in 2026, and ALK will increasingly invest
in digital solutions and AI with multiple projects being initiated
across functional areas.
ALK also continues to execute initiatives
under the Cultivate strategic pillar, including
work to deliver on science-based CO
2
targets,
strengthening organisational capabilities to
support future growth and conducting busi-
ness in a responsible manner. 2025 brought
broad-based progress for these priorities.
Please refer to the Sustainability section on pages
37-84.
Management's
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Business
strategy
Review of Allergy
+
implementation
Financial ambitions
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Review of Allergy+ implementation 16
Status on the R&D pipeline
Over the past decades, ALK has pioneered the development of standardised allergen extracts, formulated as rapidly dissolving
SLIT tablets. ALK is now expanding its leadership and targeting new geographies and patient groups while also leveraging its
technology and capabilities within food allergy and other related disease areas.
Global availability of tablets
The tablet for grass pollen allergy (GRAZAX
®
or GRASTEK
®
) is approved in 34 countries in
Europe, North America, and the Asia Pacific
region. A clinical trial to support approval in
Japan continued in 2025.
The tablet for house dust mite allergy
(ACARIZAX
®
, ODACTRA
®
, MITICURE™ or SENSI-
MUNE™) is approved in >40 countries in
Europe, North America, the Middle East, and
the Asia Pacific region. A clinical trial to support
approval in China was initiated in 2025.
The tablet for tree pollen allergy (ITULAZAX
®
or ITULATEK
®
) is approved in >20 countries in
Europe and Canada. The tablet for ragweed
pollen allergy (RAGWIZAK
®
or RAGWITEK
®
) is
approved in 15 countries in Europe and North
America.
The tablet for Japanese cedar pollen allergy
(CEDARCURE™) is approved in Japan.
The tablets for grass, ragweed, and cedar
pollen allergies are approved for all age
groups – children, adolescents, and adults.
ALK and its partners are in the process of
creating similar positions for the tablets for
house dust mite allergy and tree pollen allergy.
Therapeutic area and
project name Target indication Phase
Respiratory allergy
HDM SLIT-tablet House dust mite allergic rhinitis
Tree SLIT-tablet Tree pollen allergic rhinitis
Grass SLIT-tablet
1
Grass pollen allergic rhinitis in Japan
HDM SLIT-tablet
2
House dust mite allergic rhinitis in China
Food allergy
Peanut SLIT-tablet Peanut allergy
Tree nut SLIT-tablet Tree nut allergy
ALK 014 (biologic) Food allergy
Anaphylaxis
Adrenaline autoinjector Emergency treatment of anaphylaxis
Adrenaline nasal spray
3
Emergency treatment of anaphylaxis
New therapeutic areas
Adrenaline nasal spray
3
Acute flares in chronic spontaneous urticaria (CSU)
ALK 014 (biologic) Not disclosed
P = Pre-clinical, R = Registration, = Current phase, = Phase in preparation, = Previous phase or phases to come
1
Partnership with Shionogi;
2
Partnership with GenSci;
3
Partnership with ARS Pharma
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
P 1 2 3 R
Management's
review
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Business
strategy
Review of Allergy
+
implementation
Financial ambitions
Financial
performance
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Review of Allergy+ implementation 17
Financial ambitions
The Allergy
+
strategy targets sustained growth in revenue and earnings
to 2028 and beyond. ALK is well on its way to delivering on the long-term
financial ambitions.
ALK will be disciplined about capital allocation to ensure flexibility to deliver on its growth ambitions while also generating attractive shareholder returns. ALK expects
to generate increasing free cash flow, and cash will be allocated in the following order of priority: 1) Investments in organic growth, including R&D; 2) Business develop-
ment and licensing activities, M&A. and finally 3) cash distribution to shareholders via dividends and/or share buyback programmes.
≥10 % ~2 5% ≤2
Ambition: Average revenue growth of minimum
10% in local currencies (5-year CAGR) 2023-2028.
Result: Average growth of 15% in local currencies
2023-25.
Outlook: 11-15% growth targeted for 2026.
Ambition: An EBIT margin of around 25% in 2025
after which earnings improvements beyond the
~25% margin will be re-invested in initiatives to
bolster long-term growth and profitability.
Result: EBIT-margin of 26% in 2025.
Outlook: ~25% EBIT margin targeted for 2026.
Ambition: In line with ALK’s growth strategy and
2028 financial ambitions, ALK will maintain an
efficient capital structure with a financial gearing
of maximum two (NIBD/EBITDA) (which may
temporarily be increased in case of special circum-
stances, e.g. M&A and/or significant Business
Development & Licensing or similar).
Result: The NIBD to EBITDA ratio was reduced to
-0.4 in 2025.
Revenue growth EBIT margin NIBD/EBITDA
Management's
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+
implementation
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Financial
performance
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Annual Report 2025Financial ambitions 18
Sales and market trends
ALKs full-year revenue grew by 15% in local currencies to DKK 6,312
million (5,537), following double digit growth in all sales regions.
Respiratory tablets and anaphylaxis products (Jext
®
and
neffy
®
)
were key contributors to growth.
(Comparative figures for 2024 are shown in
brackets. Revenue growth rates are organic
and stated in local currencies, unless other-
wise indicated)
Tablet revenue grew by 17%, underscoring the
tablet portfolio’s position as ALK’s primary
revenue source. Growth was particularly driven
by the continued expansion of patient and
prescriber bases in Europe and North America
with paediatric tablet launches adding to the
sales momentum. The number of new patients
initiating treatment with tablets in 2025 is esti-
mated to have increased by well-above 10%.
Anaphylaxis revenue increased by 58%, mainly
driven by Jext
®
while
neffy
®
contributed by
approximately 26 percentage points to anaphy-
laxis revenue growth. Single-digit growth was
seen in the combined SCIT/SLIT drops sales.
Europe
Revenue in Europe grew by 14% to DKK 4,459
million (3,914) on broad-based growth across
the region, including the regions largest
markets Germany and France. Demand was
solid and market conditions largely stable.
The 19% increase in European tablet sales
was mainly driven by higher volumes linked to
a strong inflow of new patients on ACARIZAX
®
throughout 2025, but also more patients
having started treatment on pollen tablets
over the past years. The new paediatric indi-
cations for ACARIZAX
®
and ITULAZAX
®
added
incrementally to growth. Generally, the highest
contribution to growth came from ACARIZAX
®
and ITULAZAX
®
whereas GRAZAX
®
continued to
grow steadily.
While tablet sales grew across brands and
markets, performance was particularly strong
in Germany as well as Central and Eastern
European markets. Sales also grew by double
digits – although from a low level – in the UK,
where ACARIZAX
®
and ITULAZAX
®
were the
first AIT products to be admitted to the public
National Health Service systems with general
reimbursement.
In contrast to previous years, the impact of
pricing adjustments was limited, and tablet
sales continued to be only marginally impacted
by pan-European trading patterns at whole-
saler levels.
Combined sales of injection- and drop-based
products (SCIT/SLIT drops) increased by
3%. Sales of SLIT drops, marketed mainly
in France, benefitted from growing patient
and prescriber bases, while SCIT sales grew
modestly due to fewer patient initiations. In the
main SCIT markets, Germany and the Nordics,
patient initiations were partly impacted by
constrained capacity at allergy clinics, partly
by patients choosing tablets over SCIT for indi-
cations covered by the tablet portfolio.
Sales of Anaphylaxis & other products
increased by 34%, driven by 40% growth in the
anaphylaxis portfolio. Sales of Jext
®
adrena-
line pens benefited from strong commercial
execution and tender wins in Southern Europe
as well as competitors’ supply issues. Anaphy-
laxis revenue also included a modest contribu-
tion from the initial market introductions of
EUR
neffy
®
.
North America
Revenue in North America increased by 19%
in local currencies to DKK 1,037 million (906),
fuelled by tablets and Anaphylaxis & other
products. The US business recovered from last
year’s stagnancy and reported double-digit
growth, while growth was higher in Canada,
where tablets are the main product line.
Tablet sales in North America were up 24%,
mainly due to higher volumes. US tablet sales
benefited from the paediatric indication for
the house dust mite tablet, which led to higher
Management's
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Business Business
strategystrategy
Financial Financial
performanceperformance
Sales and market Sales and market
trendstrends
Financial highlights Financial highlights
and key ratios for the and key ratios for the
ALK GroupALK Group
Financial reviewFinancial review
Q4 reviewQ4 review
Corporate Corporate
mattersmatters
Sustainability
statement
Financial
statements
Annual Report 2025Sales and market trends 19
Financial performance
2021 2022 2023 2024 2025
3,916
4,511
4,824
5,537
6,312
2,809 3,058 3,216 3,914 4,459
683
857
908
906
1,037
424
596
700
717
816
2021 2022 2023 2024 2025
1,774 2,102 2,296 2,851 3,335
1,655
1,748
1,939
2,052
2,145
487
661
589
634
832
3,916
4,511
4,824
5,537
6,312
53%
6%
34%
7%
The AIT and anaphylaxis markets
The global market for allergy immuno-
therapy (AIT) is estimated to be worth
around DKK 13 billion, measured in
2025 ex-factory sales. The market is
underpenetrated and – despite recent
progresses in Asia - still largely clus-
tered around Europe, North America,
and Japan.
Globally, the AIT market is estimated to
have grown by high single-digit in 2025,
consistent with the average market
growth since 2019. During the same
period, ALK has strengthened its market
leading position with an average growth
of 12% per annum (CAGR) in sales of AIT
(tablets, SCIT and SLIT drops).
In 2025, ALK also strengthened its
position in the European anaphylaxis
market, estimated to be worth DKK 1.6
billion in ex-factory sales and growing
by 17%. In 2026, ALK will continue its
roll-out of
neffy
®
, including in markets
such as Canada, estimated to be worth
DKK 0.5 billion, as well as high-potential
markets in Asia and the Middle East.
ALK is global market leader in AIT with
a market share approching 50%. In
anaphylaxis, ALK currently holds a
global market position of less than 5%.
adoption among existing allergist prescribers
and – to a minor extent – also new paediatric
prescribers. The strong sales growth in Canada
reflected sustained underlying demand rein-
forced by the children indications for the house
dust mite and tree tablets.
Sales of SCIT bulk allergen extracts to primarily
US allergists increased modestly by 2% after
pricing optimisations, while volumes were
slightly decreasing.
Revenue from Anaphylaxis & other products
(
neffy
®
, diagnostics, PRE-PEN
®
, and life science
products) grew by 34%. Growth was driven
by the cost compensation from ARS Pharma
related to the co-promotion of
neffy
®
to US
paediatricians as well as sales of life-science
products such as vials and diluents. After the
discontinuation of lower margin accounts
in 2024, ALK has gradually succeeded in
attracting new customers to its higher margin
life-science products.
International markets
Revenue in International markets increased by
16% in local currencies to DKK 816 million (717),
reflecting some impact from timing of ship-
ments of products to China and Japan.
Tablet revenue was up 8%. Although still small
in scale, revenue continued to grow in Middle
Eastern and Southeast Asian markets as well
as in India. Revenue from the primary tablet
market Japan (product shipments and sales
royalties) was impacted by phasing of ship-
ments, particularly in the second half of 2025.
Demand in Japan remained strong and ALK’s
partner Torii (now part of Shionogi) continued
to grow in-market sales by double-digits and
consolidate its position as market leader,
although capacity constraints prevented Torii
from fully meeting demand for CEDARCURE
®
tablets.
SCIT revenue grew by 44%, driven by resumed
product shipments to China, the region’s
largest SCIT market, after the renewal of ALK’s
import license in late 2024. Chinese in-market
sales continued to grow by double digits,
facilitated by the ongoing expansion of the
prescriber base. In Q4, sales and marketing of
ALK’s products were handed over to ALK’s new
partner GenSci, positioning it as the second
largest player in the Chinese AIT market.
Revenue composition in 2025
Tablets, %
SCIT/SLIT drops, %
Anaphylaxis, %
Other products
(diagnostics, etc.), %
5-year revenue development by geography
Europe, mDKK
North America, mDKK
Int’l markets, mDKK
5-year revenue development by product line
SLIT-tablets, mDKK
SCIT/SLIT drops, mDKK
Anaphylaxis &
other products
Revenue by geography
1
Amounts in DKKm 2025
Growth
in l.c. 2024
Europe 4,459 14% 3,914
North America 1,037 19% 906
International
markets 816 16% 717
Total revenue 6,312 15% 5,537
1
ESRS 2-SBM1-40(a.ii, f)
Revenue by product line
2
Amounts in DKKm 2025
Growth
in l.c. 2024
Tablets 3,335 17% 2,851
SCIT/SLIT drops 2,14 5 5% 2,052
Anaphylaxis &
other products 832 34% 634
Total revenue 6,312 15% 5,537
2
ESRS 2-SBM1-40(a.i, f)
Management's
review
Introduction
Business
strategy
Financial
performance
Sales and market
trends
Financial highlights
and key ratios for the
ALK Group
Financial review
Q4 review
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Sales and market trends 20
Amounts in DKKm/EURm
2
DKK
2025
DKK
2024
DKK
2023
DKK
2022
DKK
2021
EUR
2025
EUR
2024
Income statement
Revenue 6,312 5,537 4,824 4,511 3,916 845 742
EBITDA 1,982 1,363 911 708 534 265 183
Operating profit (EBIT) 1,654 1,091 666 470 292 221 146
Net financial items (19) (34) (19) (23) (13) (3) (5)
Profit before tax (EBT) 1,635 1,057 647 447 279 219 142
Net profit 1,197 815 486 335 219 161 109
Average number of employees (FTE) 2,737 2,789 2,752 2,609 2,492 2,737 2,789
Balance sheet
Total assets 9,0 57 8,246 6,726 6,308 5,830 1,213 1,10 5
Invested capital 5,245 5,003 3,765 3,400 2,931 702 671
Equity 6,445 5,373 4,447 3,988 3,480 863 720
Net interest-bearing debt (NIBD) (822) 598 291 475 516 (110) 80
Cash flow and investments
Cash flow from operating activities 1,817 1,213 667 416 468 243 163
Cash flow from investing activities (385) (1,417) (375) (351) (266) (51) (190)
– of which investment in intangible
assets (84) (1,043) (69) (55) (45) (11) (140)
– of which investment in tangible
assetss (276) (260) (310) (298) (218) (37) (35)
– of which acquisitions of
companies and operations (10) (115) - - - (1) (15)
Free cash flow 1,432 (204) 292 65 202 192 (27)
1
Management’s review comprises pages 1-84 as well as ‘Financial highlights and key ratios by quarter for the ALK Group’ on
page 143.
2
Financial highlights and key ratios stated in EUR constitute supplementary information to the Management’s review. The
exchange rate used in translating from DKK to EUR is the exchange rate prevailing on 31 December 2025 (EUR 100 = DKK 747)
(31 December 2024: EUR 100 = DKK 746).
For definitions and reconciliation of alternative performance measures, see page 125.
Amounts in DKKm/EURm
2
DKK
2025
DKK
2024
DKK
2023
DKK
2022
DKK
2021
EUR
2025
EUR
2024
Information on shares
Proposed dividend 355 - - - - 48 -
Share capital 111 111 111 111 111 14.9 14.9
Shares in thousands of DKK 0.5 each 222,824 222,824 222,824 222,824 222,824 222,824 222,824
Share price, at year end 229 159 101 96 172 30.6 21,3
Net asset value per share 29 24 20 18 16 3.9 3.2
Key figures
Gross margin – % 67.1 64.2 62.9 61.9 61.2 67.1 64.2
EBIT margin – % 26.2 19.7 13.8 10.4 7.5 26.2 19.7
Return on equity (ROE) – % 18.8 16.6 11.5 9.0 6.6 18.8 16.3
NIBD/EBITDA (0.4) 0.4 0.3 0.7 1.0 (0.4) 0.4
ROIC incl. goodwill – % 32.3 24.9 18.6 14.8 10.2 32.3 24.9
Pay-out ratio – % 30.0 - - - - 30.0 -
Earnings per share (EPS) 5.4 3.7 2.2 1.5 1.0 0.7 0.5
Earnings per share (DEPS), diluted 5.4 3.7 2.2 1.5 1.0 0.7 0.5
Cash flow per share (CFPS) 8.2 5.5 3.0 1.9 2.1 1.1 0.7
Price earnings ratio (PE) 42 43 46 63 172 42 43
Share price/Net asset value 7.9 6.6 5.1 5.4 11.0 7.9 6.6
Revenue growth – %
Organic growth 15 15 9 13 12 15 15
Exchange rate differences (1) - (2) 2 - 1 -
Acquisitions/divestments - - - - - - -
Total growth revenue 14 15 7 15 12 14 15
Financial highlights and key ratios for the ALK Group
1
Management's
review
Introduction
Business
strategy
Financial
performance
Sales and market
trends
Financial highlights
and key ratios for the
ALK Group
Financial review
Q4 review
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Financial highlights and key ratios for the ALK Group 21
2021 2022 2023 2024 2025
3,916
4,511
4,824
5,537
6,312
12%
13%
9%
15% 15%
2021 2022 2023 2024 2025
3,916
4,511
4,824
5,537
6,312
61%
62%
63%
64%
67%
2,396 2,791 3,035 3,552 4,234
1,520
1,720
1,789
1,985
2,078
Financial review
ALKs full-year operating profit (EBIT) increased by 53% in
local currencies to DKK 1,654 million (1,091). Overall results
were in line with the latest financial outlook announced in
November 2025 and exceeded the previous outlooks from
February and August 2025.
(Comparative figures for 2024 are shown in
brackets. Revenue growth rates are stated in
local currencies, unless otherwise indicated)
The better-than-expected performance rela-
tive to previous outlooks was mainly driven by
the momentum for tablets in Europe and sales
of adrenaline autoinjectors, as well as opera-
tional efficiencies.
Revenue increased by 15% in local currencies
to DKK 6,312 million (5,537), driven by a strong
growth in sales of tablets and anaphylaxis
products. Exchange rates impacted reported
revenue growth negatively by approximately 1
percentage point.
Cost of sales increased by 5% in local curren-
cies to DKK 2,078 million (1,985). The gross
profit of DKK 4,234 million (3,552) yielded
a gross margin of 67% (64%), driven by
increased sales volumes, a more favourable
sales mix, and production efficiencies.
Capacity costs to R&D, Sales & marketing,
and Administration increased by 6% in local
currencies to DKK 2,581 million (2,464).
R&D expenses increased by 15% to DKK 609
million (531), mainly reflecting funding of
the peanut tablet clinical trial, pre-clinical
development projects, and the bridging trial
of ACARIZAX
®
in China. Sales and marketing
expenses increased by 3% to DKK 1,584 million
(1,564), driven by the launches of paediatric
tablets and
neffy
®
. Administrative costs of DKK
388 million (369) increased by 4%.
In 2024, capacity costs included one-off costs
of DKK 75 million associated with optimisation
initiatives in Europe and China which mainly
impacted Sales & marketing expenses. No
such costs were incurred in 2025.
EBIT (operating profit) improved by 53% in
local currencies to DKK 1,654 million (1,091),
raising the EBIT margin to 26% from 20%.
Progress was driven by higher sales, improved
2025 guidance history
DKK
2025E
19 February
outlook
2025E
12 August
outlook
2025E
12 November
outlook
2025
Actual
Revenue 9-13% ( l.c.) 12-14% (l.c.) 13-15% ( l.c.) 15% (l.c.)
EBIT margin ~2 5% ~25% ~26% 26%
Revenue
Revenue, mDKK
Revenue growth, %
Gross margin
Revenue, mDKK
Gross profit, mDKK
Cost of sales, mDKK
Gross margin, %
Management's
review
Introduction
Business
strategy
Financial
performance
Sales and market
trends
Financial highlights
and key ratios for the
ALK Group
Financial review
Q4 review
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Financial review 22
2021 2022 2023 2024 2025
631
665
618
531
609
16%
15%
13%
10% 10%
2021 2022 2023 2024 2025
1,474
1,657
1,753
1,933
1,972
38%
37%
36%
35%
31%
240 276 331 369 388
1,234
1,381
1,422
1,564
1,584
2021 2022 2023 2024 2025
292
470
666
1,091
1,654
7%
10%
14%
20%
26%
gross margin, and a lower capacity cost-to-
revenue ratio of 41% (45%). Exchange rates
impacted growth in reported EBIT negatively
by approximately 1 percentage point.
Net financials showed a loss of DKK 19 million
(a loss of 34) related to interest expenses and
currency losses.
Tax on the profit totalled DKK 438 million
(242), and the net profit increased by 43% in
local currencies to DKK 1,197 million (815).
Cash flow from operating activities was
DKK 1,817 million (1,213) mainly driven by
higher earnings and the upfront payment of
DKK 244 million from GenSci.
Cash flow from investing activities was
DKK minus 385 million (minus 1,417 which
included the DKK 115 million PRE-PEN
®
acqui-
sition and the upfront payment of DKK 1 billion
to ARS Pharma related to the
neffy
®
license
agreement) reflecting the continued build-up
of capacity for tablet production, upgrades
to legacy production, as well as a milestone
payment to ARS Pharma of DKK 32 million
related to the first commercial sale of EUR-
neffy
®
as well as investments in the next gene-
ration adrenaline autoinjector.
Free cash flow was positive at DKK 1,432
million (negative at 204).
Research and development
Research and development expenses
Percentage of revenue
Sales, marketing and administration
Administrative expenses
Sales and marketing expenses
Percentage of revenue
EBIT
EBIT
EBIT margin
Cash flow from financing activities
amounted to DKK minus 760 million (positive
310), mainly related to repayment of loans.
At the end of 2025, ALK held 1,261,283 own
shares or 0.6% of the share capital, which is
equivalent to year-end 2024.
Equity totalled DKK 6,445 million (5,373) at the
end of the year, and the equity ratio was 71%
(65%).
Revenue
DKK 6,312 million
increased by 15% in local currencies
EBIT margin
26%
from 20% in 2024
EBIT (operating profit)
DKK 1,654 million
improved by 53% in local currencies
Gross margin
67%
from 64% in 2024
Gross profit
DKK 4,234 million
an increase from 3,552 in 2024
Management's
review
Introduction
Business
strategy
Financial
performance
Sales and market
trends
Financial highlights
and key ratios for the
ALK Group
Financial review
Q4 review
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Financial review 23
Q4 review
ALKs Q4 revenue increased by 17% to DKK 1,733 million
(1,499), following double-digit growth in all sales regions. In Q4,
respiratory tablets and anaphylaxis products (Jext
®
and
neffy
®
)
remained key drivers, and growth was further supported by
shipments of SCIT products to China. Operating profit (EBIT)
increased by 88% to DKK 387 million (205), equivalent to an EBIT
margin of 22% (14%).
(Comparative figures for Q4 2024 are shown
in brackets. Revenue growth rates are
stated in local currencies, unless otherwise
indicated)
ALK delivered 2025 full-year results in line
with the most recent financial outlook,
following a Q4 where revenue increased by
17%, driven by strong performance across
the sales regions. Exchange rates impacted
reported revenue growth negatively by
approximately 1 percentage point.
Global tablet revenue grew by 15%, driven by
the expanding patient and prescriber bases
in Europe and North America. Anaphylaxis
revenue increased by 112%, due to the
neffy
®
co-promotion deal in the USA, the launch
in Europe, as well as the contribution from
Jext
®
.
Revenue in Europe increased by 14%,
fuelled by a 20% growth in tablet sales which
was driven by higher volumes linked to the
inflow of new patients starting treatment
across the tablet brands. Combined sales
of injection- and drop-based AIT (SCIT/SLIT
drops) increased by only 2% partly linked to
patients choosing tablets over SCIT for indi-
cations covered by the tablet portfolio, while
sales of Anaphylaxis & other products (Jext
®
,
neffy
®
and diagnostics) increased by 40%,
mainly driven by the Jext
®
sales.
Revenue in North America increased by
24%, reflecting continued growth in tablet
sales in both the USA and Canada, improved
performance in sales of life-science prod-
ucts in addition to the cost compensation
from ARS Pharma related to the co-pro-
motion of
neffy
®
to US paediatricians. SCIT
bulk allergen extracts to US allergists grew
modestly.
Revenue in International markets
increased by 36%, reflecting higher ship-
ments of SCIT products to China, where last
year's sales were absent due to the renewal
of ALKs import license. Tablet sales declined
slightly due to the timing of shipments of
tablets to Torii (now fully owned subsidiary
of Shionogi) in Japan. In-market sales in both
countries continued to show double-digit
growth.
The gross margin improved to 68% (64%),
mainly reflecting increased sales volumes, a
more favourable sales mix, and production
efficiencies. The temporary lower growth in
product shipments to international markets
also enhanced the gross margin.
Capacity costs increased by 8% to DKK
794 million (749) as ALK advanced its stra-
tegic growth investments. R&D expenses
increased by 14% in local currencies and
included increasing costs to the peanut
tablet development programme and the
ongoing trial with ACARIZAX
®
in China.
Sales and marketing expenses increased,
reflecting continued high investments in the
ongoing paediatric and
neffy
®
launches, as
well as generally high activity levels in key
markets. Last year, capacity costs included
one-off costs of DKK 26 million whereas no
such costs were recognised this year. The
capacity costs to revenue ratio was 46%
(50%).
Operating profit (EBIT) increased by 88%
in local currencies to DKK 387 million (205),
yielding an operating margin of 22%. As
expected, increasing strategic growth
investments led to a lower operating margin
compared to the first nine months of the
year. Exchange rates impacted growth in
reported EBIT negatively by approximately 1
percentage points.
Revenue by geography
DKKm
Q4
2025
Growth
(l.c.)
Q4
2024
Europe 1,296 14% 1,13 8
North America 270 24% 235
Int’l markets 167 36% 126
Overall revenue 1,733 17% 1,499
Revenue by product line
DKKm
Q4
2025
Growth
(l.c.)
Q4
2024
SLIT tablets 910 15% 795
SCIT/SLIT drops 607 11% 552
Anaphylaxis & other products 216 50% 152
Overall revenue 1,733 17% 1,499
Income statement
DKKm
Q4
2025
Q4
2024
Revenue 1,733 1,499
Cost of sales 553 545
Gross profit 1,180 954
Gross margin 68% 64%
Research and development expenses 189 167
Sales and marketing expenses 473 474
Administrative expenses 132 108
Other operating items, net 1 -
Operating profit (EBIT) 387 205
Net financials 6 (7)
Profit before tax (EBT) 393 198
Net profit 266 170
Operating profit before depreciation and
amortisation (EBITDA) 482 281
Management's
review
Introduction
Business
strategy
Financial
performance
Sales and market
trends
Financial highlights
and key ratios for the
ALK Group
Financial review
Q4 review
Corporate
matters
Sustainability
statement
Financial
statements
Annual Report 2025Q4 review 24
Risk management
ALKs Executive Leadership Team is responsible for the
ongoing management of risks throughout the value
chain, including risk identification, the assessment of
probabilities and potential consequences, and the
introduction of risk-reducing measures.
The Executive Leadership Team has a Risk
Committee to assist in meeting its overall
responsibility for risk management. The Risk
Committee comprises representatives from
each functional area relevant to ALK’s risk
profile. The Risk Committee meets twice a year
or more, as and when required, to perform
its tasks. Risks are systematically assessed
according to a two-dimensional matrix, rating
the potential impact and probability of each
risk. A risk management report with key enter-
prise risks and recommended mitigation plans
is presented to the Executive Leadership Team
before it is submitted to the Board of Directors
each year for their review and approval.
The following is a description of ALK’s key
enterprise risks and the main initiatives taken
to mitigate these risks. The risk movements
compared to the previous year are indicated.
Risk impact
The impact of the risk has increased
compared to the year before
The impact of the risk has not
changed compared to the year before
The impact of the risk has decreased
compared to the year before
Management's
review
IntroductionIntroduction
Business Business
strategystrategy
Financial Financial
performanceperformance
Corporate Corporate
mattersmatters
Risk managementRisk management
Corporate Corporate
governance and governance and
ownershipownership
Board of DirectorsBoard of Directors
Executive Executive
Leadership TeamLeadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Risk management 25
Corporate matters
Description
The threat of cyber attacks continues to intensify
globally and ALK is no exception. Disruption to IT
systems, such as severe breaches of data secu-
rity, may occur across the global value chain,
where well-functioning IT systems and infra-
structure are critical for the company’s ability to
operate effectively.
Risk mitigation
ALK has an IT and cybersecurity strategy in
place to prevent intruders from causing damage
to systems or gaining access to critical data
and systems. ALK continuously invests in
upgrading IT security. Awareness campaigns,
access controls, intrusion detection, prevention
systems, and IT disaster recovery plans have
all been implemented. Further initiatives are
planned, and systems are regularly upgraded to
increase network security.
2025 movement
The impact of the risk has not changed
compared to the year before
Severe IT security breaches
Description
The degree of market approval and accept-
ance for a new product, or a new indication
for an existing product, depends on several
factors, including the demonstration of clinical
efficacy and safety, cost-effectiveness, reim-
bursement/market access, convenience and
ease of administration, potential advantages
over alternative treatment methods, competi-
tion, and marketing and distribution support. If
ALK’s products, primarily tablets and anaphy-
laxis products, fail to achieve acceptance in
major markets, this could have a significant
impact on the company’s ability to generate
revenue.
ALK’s strategic commercial partnerships
and collaboration agreements expose the
company to risks related to partner perfor-
mance, alignment of strategic objectives
and execution capabilities. Partnerships
for co-promotion, development, or regional
commercialisation may fail to deliver expected
results due to operational challenges, insuf-
ficient market performance or collaboration
issues. Failure of key partners to meet contrac-
tual obligations could adversely affect reve-
nues, market presence, and strategic growth
plans.
Price pressures mandated by authorities can
have a significant impact on the companys
earning capacity. In most of the countries in
which ALK operates, prescription drugs are
subject to reimbursement from, and price
controls by national authorities and health-
care providers. This often results in significant
price differences between individual markets.
Exceptionally, governments and national
authorities may introduce permanent or
temporary economic measures that also affect
the pricing and reimbursement of medicines,
for example, because of a major economic
downturn.
Fluctuations in geo-political stability, trade
relations, or regulatory environments in key
regions may disrupt business operations, and
market access, leading to potential financial
losses and reputational damage for ALK.
Risk mitigation
ALK closely monitors economic, market and
regulatory developments as they relate to
product pricing, along with the competi-
tive situation and initiatives in all important
markets. ALK regularly conducts surveys of
market conditions and commits significant
resources to providing information on allergy
treatment to doctors and patients. ALK
continues its focus on market access strate-
gies, especially in the USA, Spain, Canada, and
UK.
ALK mitigates commercial partnership risks
through structured governance frameworks,
including Joint Steering Committees, regular
performance and milestone reviews, and
escalation mechanisms to address under-
performance. Additional mitigating actions
include proactive monitoring of sales trends,
implementation of corrective commercial
measures, enhanced clinical execution and
regulatory engagement.
ALK actively engages in dialogue with author-
ities with the aim of securing fair pricing and
reimbursement agreements and maintains a
strong focus on its market access strategy.
ALK is strongly committed to evidence-based
medicine, based on strong clinical and health
economic evidence as the basis for pricing and
reimbursement.
ALK consistently monitors the geo-political land-
scape and proactively implements mitigating
measures in pertinent regions as needed.
2025 movement
The impact of the risk has increased
compared to the year before
Commercial risks impacting revenue growth
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Risk management 26
Description
ALK’s products are subject to many statutory
and regulatory requirements with respect to
issues such as safety, efficacy, and quality. The
products may be associated with side-effects
such as allergic reactions of varying extent,
duration, and severity. Meeting pharmaceu-
tical quality standards is a prerequisite for
the company’s ability to supply products and
hence its competitive strength, and for the
company’s earnings and sales.
As ALK continues to rationalise its product
portfolio, there may be risks associated with
the discontinuation of its products. Among
others, these may include potential production
interruptions at manufacturing sites during
decommissioning and change-over work, loss
of sales from products for which no suitable
ALK substitute product exists, or inability to
meet sudden spikes in demand for other prod-
ucts due to patients switching from discon-
tinued products.
As part of its supply chain, ALK is dependent
on selected key third parties for key production
processes and supplies, which poses a risk
for ALK’s ability to deliver products, especially
tablets, to the markets.
Risk mitigation
ALK stringently monitors product and manufac-
turing quality compliance and safety via quality
assurance, pharmacovigilance and sales and
marketing activities. If, despite the high levels
of quality and safety, a situation should occur
in which it is necessary to recall a product, ALK
has procedures in place to ensure that this
can be managed swiftly and effectively and
in accordance with regulatory requirements.
Production and manufacturing processes are
subject to periodic and routine inspections by
regulatory authorities as a regular part of their
monitoring to ensure that ALK observes the
prescribed requirements and standards.
ALK has invested significantly in recent years
to increase the robustness and compliance
of the legacy business by reducing manufac-
turing complexity, and all possible steps are
taken during portfolio rationalisation work to
mitigate any potential impact on other areas
of manufacturing or the wider business. ALK
conducts risk planning including the prevention
of unwanted events, and preventive inventory
management.
ALK manages key third-party dependency
risks through long-term contracts, diligent
production forecasting, monitoring, and joint
steering committees. ALK continuously moni-
tors its dependencies on key third parties and
considers relevant risk mitigation measures
including alternative supply setups.
2025 movement
The impact of the risk has not changed
compared to the year before
Production and quality issues impacting product supply and patient safety
Description
ALK is dependent on being able to attract and
retain employees across all key functions and
markets to deliver on its strategy. Failure to
attract, develop and retain the right talents may
have a material impact on the company’s market
and research efforts.
Risk mitigation
Among other things, ALK manages this risk by
fostering an inclusive culture, continuously moni-
toring and improving employee engagement,
offering its staff opportunities to develop their
professional competencies, and by continuously
monitoring the total reward packages against
the market. ALK is also focusing increasingly on
how to position itself as an attractive employer,
and how best to identify, attract and recruit
future global and local talents with the skills and
capabilities that will be required in the future.
2025 movement
The impact of the risk is decreasing
compared to the year before
Talent retention and attraction
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Risk management 27
Description
The future success of ALK depends on the compa-
ny’s ability to maintain current products and to
successfully identify, develop and market new,
innovative drugs.
A pharmaceutical product must be subjected to
extensive and lengthy clinical trials to document
qualities such as safety and efficacy before it can
be approved for marketing. During the develop-
ment process, the outcomes of these trials are
subject to significant risks. Even though substan-
tial resources are invested in the development
process, the trials may produce negative results.
The risk fluctuates over time in line with the extent
and nature of ALK’s product development activ-
ities.
Failures or delays in the development process,
or in obtaining regulatory approvals, may have
a major impact on patients who are not able to
benefit from the products, and on ALK’s ability to
achieve its long-term goals.
Risk mitigation
ALK and its collaboration partners carry out
thorough risk assessments of their research and
development programmes throughout the devel-
opment and registration processes, in the inter-
ests of risk mitigation to maximise the likelihood of
the products reaching the market.
ALK’s Scientific Committee is responsible for other
patient/product-related innovation activities.
The committee provides instrumental strategic
sparring on matters relating to R&D activities and
other patient/product-related innovation, including
reviewing R&D programmes and the overall R&D
pipeline.
2025 movement
The impact of the risk has increased
compared to the year before
Description
Compliance requirements are generally
increasing in many areas, and as ALK expands
into more markets, the company is exposed
to more complex compliance requirements.
Non-compliance with applicable regulations
and legislation, or ALK’s Code of Conduct, could
negatively impact the company’s good reputation
which is essential to operating within the pharma-
ceutical industry. Patents and other intellectual
property rights are important for developing and
retaining ALK’s competitive strength.
Risk mitigation
ALK strives to act professionally and with high
integrity throughout the company in its deal-
ings with stakeholders. ALK’s Code of Conduct
defines the company’s high standards of ethical
behaviour in relation to customers, employees,
shareholders, society, suppliers, and partners.
A few years ago, ALK established a Compliance
Committee to oversee this work and development.
Each year, all employees are asked to sign and
confirm their knowledge of the Code of Conduct
and to take an online test. ALK has established
a whistleblower scheme which allows for confi-
dential and anonymous internal and external
reporting of potential or suspected wrongdoing.
Immediate action is taken on substantiated
non-compliance.
Internal controls and policies are in place to
safeguard ALK’s intellectual property rights. The
risk that ALK might infringe patents or trademark
rights held by other companies, along with the risk
that other companies might attempt to infringe
ALK’s own patents and/or trademark rights, are
monitored and, if necessary, suitable measures
are taken.
2025 movement
The impact of the risk has not changed
compared to the year before
Breaches of legal or ethical standards Failures or delays in product development
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Risk management 28
Corporate governance and ownership
Meeting attendance and competency matrix
Name (male/female)
Board
meetings
Audit Committee
meetings
Remuneration &
Nomination Committee
meetings
Scientific Committee
meetings
Core
Competencies
Anders Hedegaard (m) ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●
Lene Skole (f)
2
● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●
Gitte Aabo (f) ● ● ● ● ● ● ● ● ● ● ● ●
Lars Holmqvist (m)
2
● ● ● ● ● ● ● ● ● ● ● ● ●
Jesper Høiland (m) ● ● ● ● ● ● ● ● ● ● ● ● ●
Bertil Lindmark (m) ● ● ● ● ● ● ● ● ● ● ● ● ● ●
Alan Main (m) ● ● ● ● ● ● ● ● ● ● ● ● ●
Katja Barnkob (f)
1
● ● ● ● ● ● ● ● ●
Nanna Rassov Carlson (f)
1
● ● ● ● ● ● ● ● ●
Lise Lund Mærkedal (f)
1
● ● ● ● ● ● ● ● ●
Johan Smedsrud (m)
1
● ● ● ● ● ● ● ● ●
1
employee-elected
2
Non-independent
Corporate governance
ALK’s Corporate Governance report, available
at https://ir.alk.net/corporate-governance
and prepared pursuant to section 107b of the
Danish Financial Statements Act, forms part
of Management’s review in the Annual Report
2025. It describes ALK’s two-tier governance
structure—covering the Board’s composition,
competences, activities, self-assessment, and
remuneration—and key elements of internal
control and risk management related to finan-
cial reporting. The report also outlines ALK’s
compliance status with the Recommenda-
tions for Corporate Governance issued by the
Danish Committee on Corporate Governance in
December 2020 and implemented by Nasdaq
Copenhagen.
Board and management composition
The Board of Directors consists of 11 non-ex-
ecutive members: seven shareholder-elected
at the Annual General Meeting (AGM) for
one-year terms, and four employee-elected
for four-year terms (last elected in 2023). No
member of the Board of Management serves
on the Board of Directors.
At the 2025 AGM, all shareholder-elected
board members were re-elected. The Board
has a preponderance of independent share-
holder-elected members; five of seven in 2025
are considered independent under the Danish
Committee on Corporate Governance defini-
tions.
By 30 June 2026, ALK is to target gender
balance among its shareholder-elected and
employee-elected board members, respec-
tively. Among the four employee-elected
members, three are female (75%) and one is
male (25%). Among the seven shareholder-
elected members, two are women (29%) and
Meeting attendance
Attended
Absent
Competencies
Core competencies
Executive experience in a global company
Life science industry
Consumer healthcare / OTC
Financial / Risk
Commercial
Digitalisation
Experience with US market
Research & Development
Role competencies:
Chair & Vice Chair
Experience at CEO level
Board experience from other companies
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Corporate governance and ownership 29
five are men (71%). The current composition of
the shareholder-elected board members is not
considered an equal gender representation as
defined by the Gender Balance Act.
ALK’s Board of Management registered with
the Danish Business Authority has equal
gender representation, as defined by the
Gender Balance Act, with a composition of
three members, of which one (33%) is female.
For the Executive Leadership Team ("ELT")
members and their direct reports in manage-
ment positions employed in the Danish parent
company, the underrepresented gender
represents 38% (21 males and 13 females).
ALK has a target of reaching a gender balance
with at least 40% of the underrepresented
gender by 2028.
The members of the Board of Directors are
presented on pages 33–34 and ALK’s Executive
Leadership Team is introduced on pages 35-36
of this annual report.
Competency matrix for the
Board of Directors
The Board of Directors represents interna-
tional business experience from management
positions in a variety of industries - particular
regard is given to the members’ insight into the
management and globalisation of R&D-driven
companies. The Board also has overall exper-
tise in sustainability matters that are material
Composition of the Board of Directors
2
2025 2024
Shareholder-
elected
Employee-
elected Total
Shareholder-
elected
Employee-
elected Total
Number of non-executive members 7 4 11 7 4 11
Number of executive members - - - - - -
7 4 11 7 4 11
Percentage of independent members 71% 0% 45% 71% 0% 45%
Board gender diversity
Male 5 1 6 5 1 6
Female 2 3 5 2 3 5
7 4 11 7 4 11
Ratio of female to male 45% 45%
Percentage of underrepresented gender 29% (f) 25% (m) 29% (f) 25% (m)
to ALK and sustainability knowledge is inte-
grated into board committees and the Board
itself. External advice on specific sustainability
topics is obtained, if needed.
1
To assess whether all core competencies
required are adequately represented, each
shareholder-elected member of the Board has
been asked to identify the primary compe-
tences they bring to the Board, in the context
of ALK’s long-term strategy. Employee-elected
members are not part of the competency
assessment. For the Chair and Vice Chair, two
additional role-specific competences have
been identified.
Remuneration
Remuneration of the Board of Directors and
the Board of Management is determined in
accordance with ALK’s remuneration policy as
adopted by the AGM in March 2024. The policy
is prepared in accordance with sections 139
and 139a of the Danish Companies Act as well
as items 4.1.1 - 4.1.6 of the latest Danish Corpo-
rate Governance Recommendations.
Highlights of the remuneration report 2025
3
ALK’s remuneration report details the compo-
sition and development of remuneration
for the Board of Directors and the Board of
Management in 2025, including individual
shareholdings. All remuneration for the Board
1
ESRS 2-GOV1-23(a, b); G1-GOV1-5(a, b)
2
ESRS 2-GOV1-21(a, b, d, e)
3
ESRS 2–GOV3; E1-GOV3-13
ALK-Abelló A/S
Bøge Allé 6-8, DK-2970 Hørshol m, Denmark,
CVR no. 63 71 79 16
Pioneers
of allergy
solutions
Remuneration report 2025
Read the full Remuneration
report 2025
ALK-Abelló A/S
Bøge Allé 6-8, DK-2970 Hørshol m, Denmark,
CVR no. 63 71 79 16
cf. art. 107b of the Danish Financial Statement Act
Corporate Governance
report 2025
Read the full Corporate
Governance report 2025
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Corporate governance and ownership 30
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
Index
70
90
110
130
150
170
of Directors and Board of Management follows
ALK’s remuneration policy, which is submitted
for advisory approval at the Annual General
Meeting (AGM) at least every four years.
Remuneration
Amounts in DKKt 2025 2024
Board of Directors
Base fee 5,600 4,90 0
Committee fees 1,190 1,138
Total 6,790 6,038
Board of Management
Base salary 17,916 17,593
Short-term incentives (cash bonus) 14,737 13,320
Pension and benefits 3,357 3,364
Long-term incentives (grant value) 7,372 6,877
Total remuneration excluding extraordinary elements 43,382 41,154
Termination payment 6,864 -
Total remuneration including extraordinary elements 50,246 41,154
Data ethics
ALK processes data from clinical trials, R&D, employees, customer interactions, and
pharmacovigilance. It adheres to its publicly communicated data ethics policy, ensuring
compliance with privacy regulations and best practices to protect confidentiality, integ-
rity, and availability. ALK is transparent about data collection, processing, and use, which
is limited to advancing scientific and medical understanding, ensuring patient safety,
improving products and services, and delivering appropriate treatments. The Board of
Directors reviews the policy regularly; it applies to all employees and is implemented daily
by relevant business units. This report complies with section 99d of the Danish Financial
Statements Act.
The report is prepared in accordance with
section 139b of the Danish Companies Act and
will be presented for an advisory vote at the
AGM on 16 March 2026.
Members of the Board of Directors received
a fixed annual base fee, which increased in
2025, with the Vice Chair and Chair receiving
double and triple the annual fee, respectively.
Members also received an additional fee for
serving as member or chair on Board commit-
tees. The base fee for serving on the Audit
Committee increased in 2025. Fees for other
committees remained unchanged.
The remuneration for the Board of Manage-
ment consisted of both fixed pay elements
(base salary and benefits) and variable pay
elements in the form of short-term incentive
(STI) and long-term incentive (LTI) plans. The
programmes reward the attainment of pre-de-
fined financial and non-financial targets linked
to the company’s strategy, as approved annu-
ally by the Board of Directors.
In 2025, the KPIs for the STI included a sustain-
ability target on CO
2
emission reduction,
aligned with ALK’s science-based target on
The ALK share in 2025
ALK OMXC25 (indexed) Pharma, biotech and life sciences (NBI-NAS, indexed)
own emissions, which accounts for 10% of
pay to the CEO and 5% for the remainder of the
Board of Management.
The base salary for members of the Board of
Management increased by 3.5% in 2025, in line
with the general increase for ALK employees in
Denmark. The CEO’s and CFO’s base salaries
were further adjusted to align more closely to
market benchmarks.
Shareholder base
ALK aims for a diversified shareholder base
by geography, investment profile, and time
horizon, aligned with its long term strategy.
To support fair valuation and liquidity, ALK
regularly discloses relevant information on
strategy, performance, market developments,
and R&D.
At 31 December 2025, ALK had 34,777 regis-
tered shareholders (37,215) owning 98.4%
of the share capital (97.8%). Most large,
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Corporate governance and ownership 31
registered shareholders were institutional
investors, mainly in Denmark, other European
countries, and North America. Excluding the
Lundbeck Foundations holding and treasury
shares, 59.2% of the B shares are free float.
Return to shareholders
ALK is listed on Nasdaq Copenhagen (ticker
symbol ALK B). The year-end, closing price
was DKK 229 versus DKK 159 in 2024 (+ 44%).
The market value of the B shares (excluding
treasury shares) was DKK 46.0 billion (32.0).
Dividend and capital structure
Considering ALK’s financial situation with a
comfortable net cash position and expected
strong cash flows, the Board of Directors
recommends resuming dividend payments to
reward shareholders directly. At the upcoming
Annual General Meeting in March 2026, the
Board of Directors proposes distribution of
approximately 30% of net profit after tax
for 2025 as dividends. The Board of Direc-
tors continuously assesses ALK’s financial
resources to ensure sufficient funds for
Financial calendar 2026
Annual General Meeting 16 March
Three-month interim report (Q1) 5 May
Six-month interim report (Q2) 20 August
Nine-month interim report (Q3) 18 November
executing ALKs strategy, including emerging
business development, in-licensing, M&A,
and other investment needs. At end 2025, net
interest bearing debt (NIBD) was DKK -822
million and NIBD/EBITDA -0.4 (0.4), well below
the long term target of maximum two.
The Board of Directors is authorised to increase
the share capital by up to DKK 11,141,196,
with or without pre emption rights for existing
shareholders, until 15 March 2027, and to let
the company acquire B shares with a nominal
value up to DKK 11,141,196 until 22 March 2028,
at up to ±10% of the official quoted price.
Investor Relations
In 2025, ALK participated in numerous meet-
ings, calls, conferences, and seminars with
analysts and investors. Regulated announce-
ments and investor news, reports, pres-
entations, call recordings, share price data,
analysts’ estimates, and related information
are available on ALK’s website. Registered
shareholders are encouraged to sign up via the
InvestorPortal.
Share information
Number A shares AA shares B shares Total
Share capital (DKK) 9,2 07,6 0 0 920,760 101,283,60 0 111,411,96 0
No. of shares 18,415,200 1,841,520 202,567,200 222,823,920
Voting rights Each share carries
10 votes
Each share carries
10 votes
Each share carries
1 vote
Shareholder overview as at 31 December 2025
A shares
(Number)
AA shares
(Number)
B shares
(Number)
Total
(Number)
Ownership
interest
(%)
Votes
(%)
Lundbeck Foundation
1
(Copenhagen, Denmark)
18,414,400 1,841,440 69,496,540 89,752,380 40.3% 67.2%
ALK (treasury shares)
2
1,261,283 1,261,283 0.6%
Board of Directors and
Board of Management
65,930 65,930 < 0.1% <0.1%
Other 800 80 131,743,447 131,744,327 59.0% 32.7%
1
This shareholder has reported to ALK that they held 5% or more of the shares on 31 December 2025.
2
To meet obligations to deliver shares under the management incentive programmes, ALK holds a number of its own shares. The holding was reduced in 2024 following the settlement of share option
and performance share programmes.
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Corporate governance and ownership 32
Anders Hedegaard
(1960, Danish, male)
Lene Skole
(1959, Danish, female)
Gitte Aabo
(1967, Danish, female)
Lars Holmqvist
(1959, Swedish, male)
Jesper Høiland
(1960, Danish, male)
Professional board member
Chair
Independent
Board member since 2020
1
Chair of the Remuneration & Nomination
Committee
Member of the Scientific Committee
The Lundbeck Foundation, CEO and direc-
torships at two other subsidiaries
Vice Chair
Not independent
Board member since 2014
1
Member of the Remuneration & Nomination
Committee
Member of the Scientific Committee
Professional board member
Independent
Board member since 2021
1
Chair of the Audit Committee
Professional board member
Not independent
Board member since 2015
1
Member of the Audit Committee
Strategic adviser, PharmaCo Consult ApS
Independent
Board member since 2023
1
Member of the Audit Committee
Competences
2
Specific expertise within management
and sales & marketing in international life
science companies.
Competences
2
Experience in management, financial and
economic expertise, experience in strategy
and communication in international
companies.
Competences
2
Global leadership experience and compre-
hensive understanding of international
management, finance, IT, and sales &
marketing, as well as insights into building
digital communities.
Competences
2
Experience in management, finance, and
sales & marketing in international life-
science companies, including medtech and
pharmaceutical businesses.
Competences
2
Management and commercial experience
from 35 years with global pharmaceutical
companies, including roles at Ascendis
Pharma,Inc.,Radius Health, Inc., and
Novo Nordisk Inc., USA. Unique expertise
in establishing and expanding commer-
cial activities in North America, including
product launches.
Directorships
2,3
Ellab; Chair and chair of the Remuneration
Committee
Rodenstock Group, Germany: Member of
the Advisory Board
Candela Medical, USA: Board adviser
Directorships
2,3
Ørsted A/S: Chair and chair of the Nomina-
tion & Remuneration Committee
Falck A/S
4
: Vice Chair and member of the
Remuneration and Nomination Committee
H. Lundbeck A/S
4
: Vice Chair and member
of the Remuneration & Nomination and
Scientific Committees
Nordea Bank Abp, Finland: Vice Chair and
member of the Audit Committee
Directorships
2,3
Rockwool Foundation: Vice chair
Dynavox Group: Chair and chair of the
Compensation Committee and member of
the Audit and Nomination Committees.
GN Foundation: Chair
Directorships
2,3
H. Lundbeck A/S: Board member and
member of the Audit Committee
The Lundbeck Foundation: Board member
and Chair of the Investment Committee
Vitrolife AB, Sweden: Board member and
member of the Audit Committee
Directorships
2,3
SciBase AB, Stockholm: Chair
Flen Health SA, Luxemburg: Board member
Allarity Therapeutics, USA: Board member
Alva Therapeutics, USA: Board member
1
All members elected by the Annual General Meeting are up for re-election each year.
2
ESRS 2-GOV1-21(c)
3
Directorships do not include those for companies that are personally owned, fully or partly, by members of the Board of Directors.
4
Board positions included in the position as CEO of the Lundbeck Foundation.
Board of Directors
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Board of Directors 33
Bertil Lindmark
(1955, Swedish, male)
Alan Main
(1963, British, male)
Katja Barnkob
(1969, Danish, female)
Nanna Rassov Carlson
(1976, Danish, female)
Johan Smedsrud
(1972, Danish, male)
Lise Lund Mærkedahl
(1967, Danish, female)
Chief Medical Officer, Vicore
Pharma Holding AB
Independent
Board member since 2021
1
Chair of the Scientific Committee
Senior Adviser,
Canson Capital Partners
Independent
Board member since 2022
1
Member of the Remuneration &
Nomination Committee
Senior Project Director, Global Cli-
nical Development, ALK-Abello A/S
Board member since 2011
Employee-elected
Senior Manager, QA Release,
ALK-Abelló A/S
Board member since 2019
Employee-elected
Senior Maintenance Supporter,
Process & Production Support,
ALK-Abelló A/S
Board member since 2019
Employee-elected
Project Director, Global Clinical
Development, ALK-Abelló A/S
Board member since 2023
Employee-elected
Competences
2
More than 30 years' experience of
global executive R&D leadership
in pharmaceuticals (Astra, Astra-
Zeneca, Almirall) and biotech
(ASLAN Pharmaceuticals, eTheRNA
Immunotherapies, Galecto Inc.).
Experience in multi therapy area
and bringing blockbuster thera-
peutics to market globally. Served
on the Research Board of Astra-
Zeneca. Participated in a range of
IPOs, acquisitions, and debt-
financing activities.
Competences
2
More than 30 years of experience
from the consumer healthcare
industry, including roles in Sanofi,
Bayer, and Roche.
Competences
2
Experience in project manage-
ment of global drug development
projects in the pharmaceutical
industr y.
Competences
2
Expertise in production and release
of ALK’s active pharmaceutical
ingredients for sublingual immuno-
therapy products.
Competences
2
Experience in HVAC systems, clean-
room testing, utensil washing and
sterilisation for the pharmaceutical
industr y.
Competences
2
Experience in the development of
new vaccines, project management
of drug discovery projects, and
most recently governance of data
digitalisation and AI projects.
Directorships
2,3
Aqilion AB, Sweden: Chair of the
Board and member of the Remuner-
ation Committee
Cellevate, Sweden: Board member
Directorships
2,3
The Lundbeck Foundation: Board
member, employee-elected
1
All members elected by the Annual General Meeting are up for re-election each year.
2
ESRS 2-GOV1-21(c)
3
Directorships do not include those for companies that are personally owned, fully or partly, by members of the Board of Directors.
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Board of Directors 34
Peter Halling
(1977, Danish)
Claus Steensen Sølje
(1972, Danish)
Henriette Mersebach
(1971, Danish)
Flora Beiche-Scholz
(1970, German)
Edward Jordan
(1967, American)
Registered with the Danish
Business authority as member of
t
he Board of Management.
President & CEO
Registered with the Danish
Business authority as member of
t
he Board of Management.
Executive Vice President &
CFO
Registered with the Danish
Business authority as member of
t
he Board of Management.
Executive Vice President,
Research & Development
Executive Leadership Team
Executive Vice President, Commer-
cial Operations Europe
Executive Leadership Team
Executive Vice President Commer-
cial Operations North America
Competences
Executive management experience
with a strong commercial, interna-
tional , and strategic background
from life-sciences, pharmaceutical
and healthcare industries.
Peter Halling holds a master's
degree in International Marketing
& Management from Copenhagen
Business School from 2003.
Competences
International experience in
management, finance, and other
CFO-related areas in the pharma-
ceutical/med tech industry.
Claus Steensen Sølje holds a
master's degree in Economics from
the University of Copenhagen from
1999.
Competences
Experience in management, innova-
tion, and research & development in
the pharmaceutical industry.
Henriette Mersebach holds a
master's degree in Medicine from
1998 and a PhD in Medicine from
2004.
Competences
International experience in leading
transformations and delivering
strong commercial execution and
growth.
Dr. Flora Beiche-Scholz holds
a degree and a Ph.D. in biology
from the University of Erlangen,
Germany.
Competences
Experience with US commercial
strategy and execution, product
launches, establishing biopharma-
ceutical companies in the US, and
therapeutic market development in
the industry.
Edward Jordan holds an MBA from
Southern New Hampshire Univer-
sity and dual bachelor’s degrees
in finance and insurance from the
University of Rhode Island.
Directorships
1
The Danish Chamber of
Commerce: Board member
Directorships
1
Sonion A/S: Board member and
member of the Remuneration &
Nomination Committee
UV Medico A/S: Board member
Directorships
1
Versatope Therapeutics: Baard
member
1
Directorships do not include those for companies that are personally owned, fully or partly, by members of the Executive Leadership Team.
Executive Leadership Team
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Executive Leadership Team 35
Christian G. Houghton
(1964, Danish)
Lika Thiesen
(1975, Danish)
Jacob Glenting
(1974, Danish)
Jan Engel Jensen
(1966, Danish)
Executive Leadership Team
Executive Vice President,
Product Supply
Executive Leadership Team
Executive Vice President,
Global People & Organisation
Executive Leadership Team
Senior Vice President,
Corporate, Portfolio & Product
Strategy
Executive Leadership Team
Senior Vice President,
Global Quality
Competences
Experience within development of
biopharmaceutical products and
specialised in CMC development
and supply operations.
Christian G. Houghton holds a
master's degree in chemical
engineering from DTU – Technical
University of Denmark.
Competences
Experience in organisational
change, people strategy and HR
programme implementation from
different stock-listed and equity-
owned companies.
Lika Thiesen holds a master's
degree and a PhD in Public Adminis-
tration from Northern Illinois Univer-
sity, USA.
Competences
Experience in pharmaceutical
commercialisation, research &
development, marketing, business
development, strategy, and general
management.
Jacob Glenting holds a master's
degree in biochemistry, and a PhD
in vaccine development.
Competences
Experience within quality assurance
from the medical and pharmaceu-
tical industry.
Jan Engel Jensen holds bachelor’s
degrees in Production Manage-
ment, Business Administration,
and a master's degree in Quality
Management in Scientific R&D.
Directorships
1
Appointed Chair of the Danish Phar-
macopoeia Commission, Danish
Medicines Agency
Directorships
1
Qlife, Sweden: Board member
1
Directorships do not include those for companies that are personally owned, fully or partly, by members of the Executive Leadership Team.
Expansion of the Executive
Leadership Team
In 2025, ALK included the two key commercial
regions, Europe and North America, in the Executive
Leadership Team (ELT) to further strengthen the
execution of ALK’s strategy, Allergy
+
.
Effective 1 October 2025, Flora Beiche-Scholz,
former Senior Vice President for ALK’s region
Europe, joined the ELT in a new position as Exec-
utive Vice President (EVP) and head of ALK’s
Commercial Operations in Europe.
Effective 5 January 2026, Edward Jordan was
appointed as new Executive Vice President (EVP)
and head of Commercial Operations in North
America.
Following the decision to elevate the two key
commercial regions into ELT, Søren Niegel, former
Executive Vice president, Commercial Operations,
was deregistered from the Danish company register
as per 1 October 2025 and he left ALK at the end of
December 2025.
ren Niegel had been with ALK since 2012 contrib-
uting considerably to ALK’s overall leadership and
success.
Management's
review
Introduction
Business
strategy
Financial
performance
Corporate
matters
Risk management
Corporate
governance and
ownership
Board of Directors
Executive
Leadership Team
Sustainability
statement
Financial
statements
Annual Report 2025Executive Leadership Team 36
Sustainability
statement
Through its mission to improve the lives of people with allergy, ALK is
committed to conducting business in a responsible and sustainable
manner. The sustainability statement, a core part of ALK’s Annual
report, is prepared in accordance with the EU Corporate Sustainability
Reporting Directive (CSRD) and the European Sustainability Reporting
Standards (ESRS). Based on a double materiality assessment,
the statement covers ALKs material environmental, social, and
governance (ESG) topics.
Management's
review
Sustainability
statement
General General
informationinformation
Environmental Environmental
informationinformation
Social Social
informationinformation
Governance Governance
informationinformation
AppendixAppendix
Financial
statements
Annual Report 2025 37
General disclosures
ESRS 2
Basis for preparation
BP1, 2
ALK continues to pursue its sustainability
ambitions while aiming to help 5 million
patients by 2030. This sustainability statement
outlines ALK’s progress towards its environ-
mental, social and governance targets, and
details ongoing initiatives to further improve
data quality and reporting. It is prepared in
accordance with the EU Corporate Sustain-
ability Reporting Directive (CSRD) and the
European Sustainability Reporting Standards
(ESRS), applicable to ALK since 1 January
2024. The statement is prepared on a consol-
idated basis for the ALK group and subsidi-
aries, in line with the financial statements.
The sustainability topics reported in the state-
ment are identified based on a double mate-
riality assessment (DMA), which covers ALK’s
operations and its upstream and downstream
value chain. For impacts, risks and opportuni-
ties extending beyond ALK’s own operations,
the statement addresses ALK’s value chain in
its policies, actions, targets and metrics.
No information on intellectual property or
know-how has been omitted.
Sources of estimation and
outcome uncertainty
Some metrics are derived from estimates. The
basis for these estimates, including assump-
tions and judgments, are described in the
relevant accounting policies. The following
estimates are deemed significant:
“Purchased goods and services” (scope 3,
category 1) greenhouse gas (GHG) emis-
sions ( see GHG emissions on page 48 and
Accounting policies – Environmental infor-
mation on page 57)
“Irrigation” (water consumption), including
"Water reused and recycled"
( see Water consumption on page 52 and
Accounting policies – Environmental infor-
mation on page 58)
“Unadjusted gender pay gap” andAdjusted
gender pay gap” ( see Diversity and remu-
neration on page 62 and Accounting policies
– Social information on page 70)
“Patients in treatment
( see Patients in treatment on page 69 and
Accounting policies – Social information on
page 71).
Changes in preparation or presentation
Comparative figures are presented for all
metrics with at least one year of historical
data, except when not available for newly
disclosed datapoints.
Following data quality enhancements, 2024
metrics on scope 3 ( see GHG emissions on
page 48) and unadjusted gender pay gap (
see Diversity and remuneration on page 62)
have been restated, to ensure consistency and
comparability. In addition, the metric on Code
of Conduct training completion ( see Metrics
on page 74) has been revised to include all ALK
employees. The 2024 figure has been restated
to reflect this updated definition of functions-
at-risk.
Disclosures stemming from other legislation
Information in compliance with Section 107d
of the Danish Financial Statements Act has
been included in Inclusive culture on pages
61-62. EU Taxonomy information is disclosed in
accordance with the EU Taxonomy Regulation
(ar ticle 8).
Incorporation by reference
Some ESRS disclosures are addressed in the
appendices and other sections of the Manage-
ments review, by exercising the option of incor-
poration by reference. The disclosures placed
outside the sustainability statement are clearly
identified with a footnote, referring to the
applicable disclosure requirement of the ESRS.
An overview of all incorporations by reference
used in the sustainability statement is listed in
the Appendix on page 77.
Management's
review
Sustainability
statement
General General
informationinformation
Basis for Basis for
preparationpreparation
Sustainability Sustainability
governancegovernance
Stakeholder Stakeholder
engagementengagement
Materiality Materiality
assessment processassessment process
Material impacts, Material impacts,
risks and risks and
opportunitiesopportunities
Environmental Environmental
informationinformation
Social Social
informationinformation
Governance Governance
informationinformation
AppendixAppendix
Financial
statements
Annual Report 2025 38General information
General information
Sustainability governance
The role of the Board of Directors and
Executive Leadership Team
GOV1,2,3
ALKs governance model ensures that sustainability is system-
atically managed and integrated into decision-making and
business strategy, promoting long-term value creation while
addressing societal and environmental challenges.
Material impacts, risks and opportunities (IROs) are managed
by the relevant corporate functions and overseen by the
Sustainability Committee. The Sustainability department
submits quarterly reports to the Committee, which oversees
the setting of targets and monitors progress and effectiveness
of due diligence, policies, actions, metrics and targets. The
Sustainability Committee Chair regularly updates the Exec-
utive Leadership Team, while the Audit Committee oversees
progress on sustainability reporting on a quarterly basis. The
Board of Directors is informed on material IROs as a part of the
strategy updates.
See Material impacts, risks and opportunities on page 43.
Material risks are embedded in ALK’s strategy via the Enter-
prise Risk Management process. The Risk Committee, chaired
by the CFO, reports ERM risks to the Board of Directors.
For further details on the composition, competences and remuneration
of the Board of Directors and ELT, see Corporate matters on pages 30-34
(refer to the incorporation by reference table on page 77 for exact refer-
ences).
Sustainability Committee
Oversee legal reporting requirements within sustainability. Make recommendations
to Executive Leadership Team on matters with strategic impact on the global
organisation
Executive Leadership Team
Approve all sustainability related
policies and strategy
Board of Directors
Overall responsible for ALK’s
sustainability strategy and
targets
Corporate functions
Responsible for daily execution of strategic activities
as well as collection of sustainability data
Corporate Finance department
Responsible for accounting policies, internal
controls, framework and guidelines for data
processes and controls
Sustainability department
Responsible for the sustainability strategy
implementation. Ensure compliance with legal
reporting requirements as well as reporting to internal
and external stakeholders
Audit Committee
Oversee sustainability
disclosures, processes,
controls and assurance
Remuneration Committee
Oversee sustainability
related remuneration
ALK's sustainability governance model
Management's
review
Sustainability
statement
General
information
Basis for
preparation
Sustainability
governance
Stakeholder
engagement
Materiality
assessment
process
Material impacts,
risks and
opportunities
Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025General information 39
Risk management and
internal controls
GOV4,5
The Sustainability department is responsible
for overseeing the DMA process, advising on
data collection and preparing the sustain-
ability statement. The Corporate Finance
department collaborates closely on numeric
data collection and gathers data quarterly for
ongoing progress tracking and verification. All
data complies with the principles outlined by
the ESRS.
The Sustainability Committee and the Audit
Committee receive an annual update on poten-
tial critical issues related to risk management
and internal controls through the management
letter from the Independent Auditor.
Key challenges in providing unified sustain-
ability disclosures across different business
units and locations include human error and
data misalignment. To minimise human error
and data misalignment, automated data
transfers and data reporting processes
are being introduced. Internal controls and
standard operating procedures have also
been established for critical metrics, and a
four-eye principle is systematically applied.
As an integral part of its core processes, ALK
performs due diligence activities relating to
people and the environment.
See Core elements of due diligence on page 78.
Management's
review
Sustainability
statement
General
information
Basis for
preparation
Sustainability
governance
Stakeholder
engagement
Materiality
assessment
process
Material impacts,
risks and
opportunities
Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025General information 40
Stakeholder engagement
Strategy, business model
and value chain
SBM1
For details on the strategy, business model and
value chain, see Introduction on pages 8-10 and
Financial performance page 20 (refer to the incor-
poration by reference table on page 77 for exact
references).
For employee headcount, see Employee charac-
teristics on page 64.
Interests and views of stakeholders
SBM2
Active engagement with stakeholders is
a fundamental aspect of ALK’s Allergy
+
strategy. The interactions shape the under-
standing of material issues and support the
sustainability initiatives. Internal engage-
ment occurs across a broad range of func-
tions including, but not limited to, finance,
legal, environment, health and safety,
procurement, people and organisation,
research and development, commercial
operations and the ELT. The Board of Direc-
tors and ELT are informed about the views
and interests of affected stakeholders
through the sustainability strategy updates.
Stakeholder engagement during the materiality
assessment process is described on page 42.
An overview of the key stakeholder groups
and how they inform Allergy
+
is provided in
the table.
Key stakeholders
How engagement
is organised Purpose of engagement Examples of outcomes
Inform Allergy
+
strategy
Employees Engagement survey
Employee-elected Board
members
Workers’ councils
Employee development
dialogues
Employee meetings
Sounding board
Strategic alignment
Understanding employees'
perceptions and experiences
Defining training needs
Human resources strategy
Improvement action plans
Training programmes
Employee information
Cultivate pillar
Consumers and
general public
Various digital media platforms
Consumer websites, apps,
email flows, etc.
Creating awareness around
allergies, symptoms, impact
on quality of life and treatment
options, etc.
Improved awareness among
consumers relating to allergies
including symptoms, impact
on quality of life, treatment
options, etc.
Innovate and
Focus pillars
Healthcare
professionals
Scientific webinars and
symposia, scientific publica-
tions, clinical trial data sharing,
etc.
Awareness of allergy, including
burden of disease and bene-
fit-risk of available allergy
treatment strategies
Increased adoption and usage
of evidence-based disease
modifying allergy treatments
Correct identification and diag-
nosis of people with allergy
Clinical practice optimisation
Innovate and
Focus pillars
Suppliers
and contract
manufacturers
Contract negotiations
Third-party code of conduct
implementation
Supplier meetings and corre-
spondence
Compliance with ALK's Third-
party Code of Conduct
Commitment to Science-Based
Targets initiative
Reliable long-term partner-
ships
Adherence to ALKs busi-
ness conduct standards and
collaborative decarbonisation
progression
Optimise pillar
Investors and
shareholders
Interim and annual reports,
company announcements,
websites, presentations, meet-
ings and events
ESG ratings
Enhancing transparency
Understanding expectations to
sustainability
Attracting responsible inves-
tors
Strong reputation
Access to capital
Fair valuation
Authorities Continuous interaction Compliance with regulations,
safety and efficacy of medi-
cines
Environmental approvals
Compliance and market access
Environmental permits
Innovate, Focus and
Optimise pillars
Management's
review
Sustainability
statement
General
information
Basis for
preparation
Sustainability
governance
Stakeholder
engagement
Materiality
assessment
process
Material impacts,
risks and
opportunities
Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025General information 41
Materiality assessment process
IRO1; E1-SBM3
Double materiality assessment
In 2025, ALK reviewed its double materiality
assessment (DMA), conducted in accordance
with the double materiality criteria outlined in
ESRS 1 and the implementation guidance from
EFRAG. This review followed the same process
as in 2024.
The purpose of the DMA is to identify and assess
impacts on the environment and society, as well
as the sustainability-related risks that ALK is
exposed to and the opportunities it leverages.
ALK is in the process of conducting an in-depth
climate-related scenario analysis for all sites to
support the identification and assessment of
physical and transition risks and opportunities
across the short, medium, and long term. As
the in-depth climate risk assessment is still
underway, current material impacts, risks and
opportunities (IROs) related to climate change
are based solely on the risk assessment using
the World Wildlife Fund (WWF) risk filters,
which did not identify any material climate-re-
lated physical or transition risks.
The WWF water risk filter was also used to
identify and assess IROs related to water and
marine resources at ALK's production sites and
source material collection points. ALK’s site
in Madrid (Spain) is located in a water scarce
region, identified using the baseline water
stress indicator from the World Resources
Institute. Water-related financial and opera-
tional risks were deemed immaterial as basin
regulatory and reputational risks are low in
regions where ALK operates.
Materiality scoring approach
The scoring approach for the DMA is inspired
by ALK’s Enterprise Risk Management (ERM)
framework. ALK defines the medium-term
as 13 years and the long-term as beyond 3
years, consistent with the ERM framework.
While the ERM accounts for risk mitigation in
its scoring, all IROs in the DMA are evaluated
at a gross level. To ensure consistency, some
members of the Sustainability Committee also
serve on the Risk Committee, ensuring that
relevant sustainability risks are incorporated
into the ERM overview.
Impact materiality: assessed on severity
(composed of scale and scope, and, for nega-
tive impacts, irremediability) and likelihood of
impacts. For potential negative human rights
impacts, severity takes precedence over the
likelihood of the impact in the scoring.
Financial materiality: assessed on the finan-
cial magnitude of the risk/opportunity, its like-
lihood, and the nature of the financial effect.
Thresholds align with the ERM framework.
Identifying
sustainability matters
The Sustainability department
reviewed 2024 sustainability
matters and conducted a
peer analysis to identify gaps.
Sustainability matters cover
ALK’s activities, business
relationships, affected stake-
holders and key parts of the
value chain with significant
impact and relevance to ALK’s
business model. ALK's activi-
ties are screened at site level.
Stakeholder
engagement
ALK engaged with relevant
internal subject matter experts
through DMA workshops, to
review, assess, refine and
consolidate the IROs. The views
and perspectives of affected
stakeholders are represented
by proxy through the
knowledge of ALK’s internal
subject matter experts.
Approval of
the DMA
Workshop results were
captured using a scoring tool
to assess the materiality of
each IRO, ensuring consistent
and harmonised outcomes.
Each score included detailed
justifications for the rationale
behind the assessment. The
final results were reviewed and
validated by all subject matter
experts. The DMA result was
presented and approved by the
ELT, the Audit Committee and
the Board of Directors.
Future steps: integration,
monitoring, and review
The DMA is reviewed on an
annual basis, considering
trends, business context, key
supplier changes, and regu-
lations. In cases where signif-
icant changes occur in ALK’s
business model, value chain, or
methodology, a more in-depth
review will be conducted to
reassess the materiality and
priorities.
Management's
review
Sustainability
statement
General
information
Basis for
preparation
Sustainability
governance
Stakeholder
engagement
Materiality
assessment
process
Material impacts,
risks and
opportunities
Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025General information 42
Financial Materiality
Non material
Impact material
Pollution
(E2)
Business conduct
(G1)
Climate change
(E1)
Affected
Communities
(S3)
Consumers and
end-users (S4)
Biodiversity &
ecosystems (E4)
Water & marine
resources (E3)
Own workforce
(S1)
Financial material
Workers in the
value chain (S2)
Double material
Impact Materiality
Circular economy
(E5)
Material impacts, risks and opportunities
SBM3; IRO2
ALK’s 2025 DMA revealed no changes in
materiality at the topic level compared to the
previous reporting year. However, Own work-
force was moved from double material to being
impact material, due to the fact that the risk
related to "employee attraction and retention"
has decreased in 2025.
Of 122 identified IROs, 21 were deemed mate-
rial, comprising 17 negative impacts, 1 positive
impact, 1 risk and 2 opportunities.
The 2025 DMA added new material IROs (S1:
“Inclusive culture”; S4: “Affordability” and
“Innovation”) to align with industry standards.
Compared to 2024, some IROs were consoli-
dated:
“Emissions from own operations” now
includes refrigerants in E1
The impact of pharmaceutical standards on
circularity is included in “Use of non-recycled
paper, single-use aluminium and single-use
plastic” in E5.
For Biodiversity, Workers in the value chain,
"Patients safety" (S4) and "Potential bribery of
healthcare professionals" (G1), the description
of the IROs was broadened.
All material IROs from ALK’s own operations
cover all production sites, with the exception of
water use in water-scarce regions that applies
only to ALK’s production site in Madrid (Spain).
The list of material disclosure requirements
and datapoints was based on the ESRS issued
by the European Commission July 2023 and the
revised Appendix C to ESRS 1. A content index
of disclosure requirements and a list of data-
points derived from other EU legislation can be
found in Appendix on pages 78-82.
The phase-in provisions have been applied for
Biodiversity E4 as well as the numeric data for
Own Workforce S1.
The material IROs identified during
the DMA are described and presented
alongside the topical standards:
E1 - Climate change, on pages 44-49
E2 - Pollution, on page 50
E3 - Water and marine resources, on pages 51-52
E4 - Biodiversity and ecosystems, on page 53
E5 - Resource use and circular economy, on pages 54-55
S1 - Own workforce, on pages 59-64
S2 - Workers in the value chain, on pages 65-66
S4 - Consumers and end-users, on pages 67-69
G1 - Business conduct, on pages 72-75.
Double materiality assessment
Environmental Social Governance
Management's
review
Sustainability
statement
General
information
Basis for
preparation
Sustainability
governance
Stakeholder
engagement
Materiality
assessment
process
Material impacts,
risks and
opportunities
Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025General information 43
Environmental information
Climate change
E1
gas emission reduction targets, approved by
the Science Based Targets initiative (SBTi) and
consistent with a 1.5˚ pathway.
To meet these targets, ALK has developed a
transition plan outlining decarbonisation levers
through 2030 ( see Actions on pages 45-46).
The plan factors in projected company growth
and locked-in emissions linked to long-term
energy-intensive assets.
CO
2
e emissions across
ALK’s value chain
(market-based)
Upstream activities Downstream activitiesALK – Own operations
Upstream transpor-
tation & distribution
1,457 t CO
2
e
Purchased goods
& services
47,16 4 t CO
2
e
Fuel & energy
related activities
3,306 tCO
2
e
Direct energy
consumption
3,058 tCO
2
e
Refrigerants
509 tCO
2
e
Company fleet
1,219 tCO
2
e
Capital goods
3,530 tCO
2
e
Employee
commuting
5,491 tCO
2
e
Waste generated
in operations
80 tCO
2
e
Business travel
1,861 tCO
2
e
Downstream
transportation and
distribution
3,593 tCO
2
e
End of life treatment
of sold products
29 tCO
2
e
Electricity
& district heating
365 tCO
2
e
Transition plan
E1-1; E1-GOV3
ALK recognises the need to address climate
change in alignment with the goals of the Paris
Agreement and has established greenhouse
Scope 1
Scope 2
Scope 3
Management's
review
Sustainability
statement
General General
informationinformation
Environmental Environmental
informationinformation
Climate changeClimate change
PollutionPollution
WaterWater
Biodiversity and Biodiversity and
ecosystemsecosystems
Resource use and Resource use and
circular economycircular economy
EU TaxonomyEU Taxonomy
Accounting policies Accounting policies
– Environmental – Environmental
informationinformation
Social Social
informationinformation
Governance Governance
informationinformation
AppendixAppendix
Financial
statements
Annual Report 2025 44Environmental information
Environmental information
Focusing on emissions from ALK’s own oper-
ations, the transition plan is embedded within
the company’s overall strategy, supported
by annual business and financial planning
processes and approved annually by the
Investment Portfolio and Sustainability
Committees.
Key actions require investments, such as
decarbonising boilers across production sites,
a taxonomy-eligible activity. As these meas-
ures will be implemented over time, the reduc-
tion pathway is not expected to be linear, but
will deliver stepwise reduction.
ALK continues its efforts to align its activities
with the EU Taxonomy for climate adaptation
and mitigation where possible ( see EU
Taxonomy on page 56) and is not excluded
from the EU Paris-aligned benchmarks.
ALK’s commitment to emission reduction is
further reinforced by sustainability-related
incentives included in the remuneration
schemes for the Executive Leadership Team,
ensuring that priority is given to decarboni-
sation ( see Incorporation by reference on
page 77).
Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Emissions from own operations
ALK generates greenhouse gas (GHG) emissions
through its direct operations, company fleet, use of
refrigerants (scope 1) and purchased energy (scope
2). These emissions contribute to climate change.
Actual
negative
impact
Value chain emissions
ALK's value chain generates GHG emissions from
purchased goods and services, capital goods,
upstream and downstream transportation & distri-
bution, and business travel. These Scope 3 emissions
contribute to climate change.
Actual
negative
impact
Climate change and respiratory health
Climate change threatens respiratory health by
extending pollen seasons, increasing airborne aller-
gens and promoting mould growth. This represents a
market opportunity for ALK.
1
Opportunity
1
see Consumers and end-users on page 67
Policies
E1-2
ALK’s transition plan is supported by a frame-
work of policies focusing on company fleet (part
of scope 1) and business travels (scope 3, cate-
gory 6). In 2025, an update of local company car
policies was initiated across European countries,
introducing requirements for either electric-only
or electric and hybrid vehicles.
Regarding scope 3 emissions, the global travel
policy was also updated. The purpose of the
policy is to ensure that all employees have a
clear and consistent understanding of general
rules and procedures for business travel. It
applies to all employees as well as any external
party travelling at ALKs expense, requiring
alternatives to business travel to be consid-
ered first. Oversight rests with the Executive
Leadership Team (ELT).
Actions
E1-3
Own operations
While immediate activities such as installing
LED lighting and sensor-controlled lighting
systems to reduce overall energy consump-
tion have already been implemented, ALK is
reducing GHG emissions from own operations
further through the following decarbonisation
levers and actions:
1. Decarbonising boilers
ALK is in the process of decarbonising
production boilers powered by natural gas
or gas oil. In 2025, the gas boiler at the
French production site was replaced with
heat pumps, with full operational impact in
2026. The remaining boiler decarbonisation
initiatives are currently planned for full imple-
mentation by 2030.
The related CapEx investments are
accounted for in ALK's annual budget
processes and are approved by the Invest-
ment Portfolio Committee. In 2025, ALK
allocated DKK 5 million in CapEx to support
the implementation of the decarbonisa-
tion project for the boiler in France ( see
Incorporation by reference on page 77).
The ability to implement the action does not
depend on specific preconditions.
2. Electrifying the company fleet
In 2025, ALK also continued the transition of
the company fleet to electric vehicles, with
an initial focus on European countries, where
the infrastructure is well developed. Some
-11% in
2025
in carbon emissions from scope 1 and 2,
compared to 2022
Management's
review
Sustainability
statement
General
information
Environmental
information
Climate change
Pollution
Water
Biodiversity and
ecosystems
Resource use and
circular economy
EU Taxonomy
Accounting policies
– Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025 45Environmental information
countries now only allow electrical vehicles,
while others are waiting for infrastructure
improvements before fully electrifying their
car fleets.
3. Substituting refrigerant chemicals in
coolers
ALK has mapped all cooling systems and
refrigerants and developed a substitution
timeline based on legal requirements,
equipment lifecycle and costs. Refrigerant
replacements will prioritise those with lower
global warming potential. A cross-depart-
mental programme has been launched to
improve management of cooling systems
and refrigerants, focusing on better moni-
toring, reporting, preventive maintenance
and substitution while maintaining opera-
tional efficiency.
4. Transitioning towards renewable energy
ALK has purchased third-party audited
Renewable Energy Certificates for electricity
since 2019. These certificates cover 100%
of ALK’s electricity consumption at produc-
tion sites where direct renewable energy
sourcing is not possible.
Operating expenditure (OpEx) is allocated
on an ongoing basis to purchase the certif-
icates. In 2025, this amounted to DKK 0.8
million ( see Incorporation by reference on
page 77).
Value chain
In 2025, ALK strengthened the quality of data
underpinning value chain emissions. As part of
a comprehensive vendor remediation exer-
cise, ALK undertook a reclassification of its
supplier portfolio, enabling a more accurate
scope 3 emission calculation. ALK also imple-
mented a global travel management platform
to ensure compliance with the travel policy
and to provide a clearer, consolidated view
of business travel emissions. In parallel, ALK
expanded supplier screening and engagement
on carbon-reduction targets and initiatives to
cover a broader share of its supply base.
Targets
E1-4
ALK has set two targets related to climate
change mitigation:
reduce its absolute carbon emissions by
42% between 2022 and 2030 in its own oper-
ations (market-based scope 1 and scope 2)
have 80% of its emissions from suppliers with
science-based targets by 2028 (scope 3).
The targets were approved by the Science
Based Targets initiative in January 2024 and
align with the global 1.5°C trajectory.
In 2022, ALK's scope 1 and 2 (market-based)
baseline accounted for 5,492 tCO
2
e, with
scope 1 representing 90%. The boundaries for
this target exclude ALK's sales offices, which
account for less than 5% of its total emissions.
The rest of the assumptions and methodolo-
gies align with the GHG emissions reporting
disclosed under GHG emissions on pages
47-49.
CO
2
reduction roadmap – Scope 1 and 2
Increase
Decrease
2022
baseline
Business
growth
1. Decarbonising
boilers
2. Electrifying
the company
fleet
3. Substituting
refrigerant
chemicals in
coolers
4. Transitioning
towards
renewable
energy
2030
target
5,492 tCO
2
e
Scope 1 and 2
3,185 t CO
2
e
Scope 1 and 2
42%
reduction
Management's
review
Sustainability
statement
General
information
Environmental
information
Climate change
Pollution
Water
Biodiversity and
ecosystems
Resource use and
circular economy
EU Taxonomy
Accounting policies
– Environmental
information
Social
information
Governance
information
Appendix
Financial
statements
Annual Report 2025 46Environmental information
2022 2023
2
2024 2025 2026 2027 2028 2029 2030
- 42% (validated SBTi target)
3,185
4,883
5,384
5,709
5,492
80% (validated SBTi target)
80%
2024 2025 2026 2027 2028
50%
35%
GHG emissions
E1-3,5,6 Retrospective Target years
Science-based targets Unit
% 2025 /
2024 2025 2024
Base year
2022 2028 2030
Annual % target /
Base year
Scope 1+2 (production sites)
Total scope 1+2 (market-based) Tonnes CO
2
e -9% 4,883 5,384 5,492 3,18 5 -5%
Change in scope 1 & 2 from a 2022 baseline % -11% -2% - -42%
Scope 3
Suppliers with science-based targets % Scope 3 emissions 15pp 50% 35%
1
N/A 80% 13pp
1
Related to the reclassification of the supplier portfolio, 2024 scope 3 figures have been restated to reflect the revised spend categorisation and ensure comparability (previously 37%).
Driven by its decarbonisation actions, ALK
decreased its scope 1 and 2 emissions to
4,883 tCO
2
e, leading to an 11% reduction
compared to the 2022 science-based target
baseline (2022: 5,492 tCO
2
e). The electrifica-
tion of the boiler in France was the main driver
of the reduction in direct energy emissions to
Total scope 1+2 (market-based)
Tonnes CO
2
eq
Suppliers with science-based targets
% scope 3 emissions
decreased to 97 tCO
2
e (2024: 459) following an
updated emission factor.
In 2025, the share of suppliers with science-
based targets increased to 50% (2024: 35%).
3,058 tCO
2
e (2024: 3,325). In addition, the tran-
sition to electrical company fleet lowered to
1,219 tCO
2
e (2024: 1,383). The decommission
of refrigerant equipment caused an unfore-
seen leak, increasing refrigerants emissions
to 509 tCO
2
e (2024: 217). ALK’s market-based
scope 2 emissions from the production sites
2
2023 figure are not covered by the Independent Auditor’s limited assurance report.
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Annual Report 2025 47Environmental information
25%
11%
64%
0,0
1,5
2022 2023
2
2024 2025
1.2
1.2
1.0
0.8
Scopes Unit 2025 2024
Base year
2022
Scope 1
Direct energy consumption Tonnes CO
2
e 3,058 3,325 3,368
Company fleet Tonnes CO
2
e 1,219 1,383 1,355
Refrigerants Tonnes CO
2
e 509 217 235
Tonnes CO
2
e 4,786 4,925 4,958
Scope 2
Location-based
Production sites Tonnes CO
2
e 5,456 6,423 5,856
Sales offices Tonnes CO
2
e 268 297 N/A
Tonnes CO
2
e 5,724 6,720 5,856
Market-based
Production sites Tonnes CO
2
e 97 459 534
Sales offices Tonnes CO
2
e 268 297 N/A
Tonnes CO
2
e 365 756 534
Scope 3
Cat. 1. Purchased goods & services Tonnes CO
2
e 47,16 4 48,694
1
49,0 96
1
Cat. 2. Capital goods Tonnes CO
2
e 3,530 3,397
1
3,974
1
Cat. 3. Fuel & energy related activities Tonnes CO
2
e 3,306 3,365
1
2,483
1
Cat. 4. Upstream transportation & distribution Tonnes CO
2
e 1,457 1,393
1
4,748
1
Cat. 5. Waste generated in operations Tonnes CO
2
e 80 89 105
Cat. 6. Business travel Tonnes CO
2
e 1,861 2,626 3,995
Cat. 7. Employee commuting Tonnes CO
2
e 5,491 5,696 5,724
Cat. 9. Downstream transportation & distribution Tonnes CO
2
e 3,593 3,14 8
1
313
1
Cat. 12. End of life treatment of sold products Tonnes CO
2
e 29 28 37
Tonnes CO
2
e 66,511 68,436
1
70,475
1
Total emissions (location-based) Tonnes CO
2
e 77,021 80,081 81,289
Total emissions (market-based) Tonnes CO
2
e 71,662 74,117 75,967
GHG intensity (scope 1 and 2 market-based) Tonnes CO
2
e/DKKm 0.8 1.0 1.2
GHG intensity (location-based) Tonnes CO
2
e/DKKm 12.2 14.5 18.0
GHG intensity (market-based) Tonnes CO
2
e/DKKm 11.4 13.4 16.8
Net revenue DKKm 6,312 5,537 4,511
Bundled energy attribute claims % - - N/A
Unbundled energy attribute claims % 88% 88% N/A
GHG scope 3 calculated using primary data % 16% 17% N/A
1
ALK is continuously improving data quality related to scope 3 emissions. 2024 figures for scope 3 categories 1-4 and 9 have been restated due to the reclassification of the
supplier portfolio and other minor data improvements (total previously 74,506 tCO
2
e). It has not been practicable to restate scope 3 for 2022, and therefore 2022 figures for
scope 3 categories 1-4 and 9 are not fully comparable.
Scope 1
Direct energy consumption
Company fleet
Refrigerants
GHG intensity
(scope 1 and 2 market-based)
Tonnes CO
2
eq/DKK
2
2023 figures are not covered by the Independent
Auditor’s limited assurance report.
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Energy consumption and mix Unit 2025 2024
Energy consumption from fossil sources
Fuel consumption from crude oil and petroleum products MWh 2,077 2,420
Fuel consumption from natural gas MWh 13,816 14,524
Consumption of purchased or acquired electricity, heat,
steam, or cooling from fossil sources MWh 9,0 94 10,14 8
MWh 24,987 27,092
Energy consumption from nuclear sources
Energy consumption from nuclear sources MWh 5,353 4,505
MWh 5,353 4,505
Energy consumption from renewable sources
Fuel consumption from renewable sources MWh - -
Consumption of purchased or acquired electricity, heat,
steam and cooling from renewable sources MWh 20,315 19,810
MWh 20,315 19,810
Total energy consumption MWh 50,655 51,407
Share of renewable sources in total energy consumption % 40% 39%
Energy intensity associated with activities in high climate
impact sectors MWh/DKKm 8.0 9.3
ALK's activities are in a high climate impact sector. Energy intensity is therefore calculated on the total revenue.
In 2025, ALK reduced its total energy consump-
tion, while delivering significant business
growth, reducing energy intensity to 8.0 MWh/
DKKm (2024: 9.3). Natural gas consumption
decreased to 13,816 MWh (2024: 14,524)
following the electrification of the boiler in
France.
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Use of substances of concern
All chemicals used by ALK are regulated under the
Registration, Evaluation, Authorisation, and Restric-
tion of Chemicals (REACH) Regulation. Some chemicals
are classified as Substances of Concern (SoCs) or
Substances of Very High Concern (SVHCs) due to their
potential environmental and human health impacts.
Improper handling, application, transport, or disposal
can have adverse environmental effects.
Actual
negative
impact
Pollution
E2
Policies
E2-1
ALK ensures compliance with REACH and local
regulations for responsible use and handling
of chemicals in production. Relevant actions
and resources are continuously evaluated and
allocated at the operational level to maintain
high environmental and safety standards.
Given the local compliance framework and
established operational controls, ALK has not
identified a need for a centralised global policy
on management of substances of concern.
Actions
E2-2
ALK continuously evaluates opportunities to
reduce or substitute SoCs or SVHCs. Substitu-
tion is sometimes limited by pharmaceutical
regulatory requirements, as specific chemical
properties are necessary to ensure product
quality and compliance with pharmaceutical
standards.
Initiatives are also directed at ensuring safe
handling, storage and use of regulated chemi-
cals on all production sites, regularly updating
procedures to reflect evolving regulations. In
2025, ALK successfully met all requirements
and inspections from local environmental
authorities. Building on efforts started in
2024, ALK further enhanced its mapping and
reporting of SoCs and SVHCs.
As a result of ALKs continued focus on SoCs
and SVHCs, the amount of SoCs procured
decreased to 3.0 tonnes (2024: 5.0), with
SVHCs accounting for 0.6 tonnes (2024: 0.9).
Targets
E2-3
ALK remains flexible and responsive to
changes in regulatory requirements, ensuring
continued compliance and a commitment to
reducing environmental impact as new phase-
outs and restrictions are adopted. Due to this,
ALK has not had the need to set specific reduc-
tion targets.
Substances of concern and substances of very high concern
E2-5
Unit 2025 2024
Substances of concern procured Tonnes 3.0 5.0
Substances of very high concern procured Tonnes 0.6 0.9
Substances of concern procured
3.0 tonnes
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Water consumption in production facilities
The consumption of water in production facilities can
contribute to local water scarcity, impacting avail-
ability and increasing water costs for surrounding
communities. Reduced water availability may also
impact local ecosystems and agriculture and increase
wildfire risks.
Actual
negative
impact
Use of water in water-scarce regions
ALK’s Madrid (Spain) production site operates in a
high-water stress area. Climate change and periodic
droughts could further constrain water resources,
potentially affecting the local population.
Potential
negative
impact
Water
E3
Policies
E3-1
ALK monitors water use across its produc-
tion facilities to ensure compliance with local
regulations and has therefore not had the need
for a formal water management policy, neither
globally nor for water-scarce areas like Madrid
(Spain).
Actions
E3-2
Water management is an integral part of the
role of the Environmental, Health and Safety
department and water meters have been
installed at all production sites to monitor
usage. In 2025, the purified water system was
upgraded at one production site, reducing
water consumption.
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45%
7%
38%
55%
Water consumption
E3-4
Unit 2025 2024
Water consumption
Irrigation m
3
100,477 312,773
Domestic water use m
3
80,625 92,533
m
3
181,102 405,306
Water consumption in areas of high-water stress m
3
11,716 11,495
Water reused and recycled m
3
11,886 18,624
Water intensity m
3
/DKKm 28.7 73.2
At ALK’s Madrid production site, located in the
water-scarce Tagus river basin, ALK has devel-
oped a 4-year water management plan, which
focuses on employee training, promoting
best practice via the Good Practice Manual,
improving leak reporting, and continuing the
rollout of water saving devices.
Strict pharmaceutical regulations on product
quality and manufacturing equipment clean-
liness limit the potential for water reuse and
recycling, as this would require advanced
water treatment and regeneration systems.
Going forward, ALK plans to explore opportu-
nities such as new technologies and process
optimisations to further enhance sustainable
water management.
ALK practices crop rotations at its farmland,
to maintain soil health, manage nutrient
balances, and support long-term yield
stability. As a results, the water used for irriga-
tion can fluctuate year on year, depending on
the number of irrigated fields.
In 2025, irrigation of allergenic source mate-
rials on ALK leased and owned farmland
accounted for 55% of total water use (2024:
77%). The crop rotations meant that fewer
fields required irrigation, reducing water used
for irrigation to 100,477 m
3
(2024: 312,773 m
3
).
The remaining water consumption covers
water for domestic use (production, drinking,
sanitary) and decreased to 80,625 m
3
(2024:
92,533), due to the upgrade of a purified water
system. 15% of the domestic water use (2024:
12%) originates from the Madrid production
site.
Targets
E3-3
ALK has not set global targets for reducing
water consumption beyond local legal require-
ments.
Water consumption
181,10 2 m
3
Water consumption
Irrigation
Domestic water use
Outside areas of high-water stress
In areas of high water stress
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Reliance on natural resources for production of
active pharmaceutical ingredients
The majority of ALK’s allergenic source materials –
pollens, mites, moulds and insect venom – are sourced
from nature on ALK’s own and leased land in North
America. These agricultural activities are not regener-
ative or organic, and can negatively affect biodiversity
and ecosystems.
Actual
negative
impact
Biodiversity and ecosystems
E4
ALK is committed to sustainable agricultural
practices and complies with all relevant
national legislation. On its main farmland in
Idaho (USA), ALK has implemented several
initiatives to support biodiversity, such as:
Diversifying crops to provide varied pollina-
tion periods for pollinators such as bees.
Practising crop rotations to maintain soil
health, manage nutrient balances, and
support long-term yield stability.
Minimising pesticide and fertiliser use
through integrated pest management.
Protecting native flora and fauna by estab-
lishing large buffer zones.
Minimising soil disturbance and erosion
through targeted lime application and no-till
practices.
Reusing mite process waste as fertiliser to
increase soil organic matter in the fields.
To further strengthen this approach, ALK plans
to conduct a comprehensive biodiversity resil-
ience analysis in the coming years, evaluating
its dependencies on natural ecosystems and
identifying additional opportunities to promote
ecological resilience across its operations.
Therefore, ALK does not currently have policies
or targets related to biodiversity in place.
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Use of non-recycled paper, aluminium and
single-use plastic
The pharmaceutical industry is highly regulated,
requiring high standards for quality and sterility, which
results in limited possibilities for circularity. The use of
single-use plastic, aluminium containers and non-recy-
cled paper in production have environmental impacts
during manufacturing and disposal.
Actual
negative
impact
Operational waste partly disposed in landfills
Some of ALK’s operational waste goes to landfills due
to limited recycling facilities in certain regions. The
extent varies depending on local waste management
infrastructure and regional regulations.
Actual
negative
impact
End of life of products
End-of-life management of ALK products also differs
by region, with recycling infrastructure for medical
products remaining limited in some countries. This
hinders the recovery of the recyclable components in
ALK products.
Actual
negative
impact
Resource use and circular economy
E5
Policies
E5-1
To address operational waste, ALK introduced
a global waste policy in 2025 with the aim of
reducing environmental impact, promoting
resource efficiency and ensuring alignment
with regulatory, technological and stra-
tegic developments. The policy establishes
a common framework for waste handling
across all ALK production sites and sets out a
commitment to reduce landfill disposal. ALK
will actively seek and implement environmen-
tally responsible and compliant alternatives
following the European waste hierarchy.
Waste requirements will be integrated
into supplier evaluation, contracting, and
performance management. Manufacturing
processes for new products will be designed
to minimise waste and incorporate materials
that are non-hazardous and easy to manage
at end of life.
The overall responsibility rests with ALK’s
Board of Directors, who have delegated this
responsibility to the Executive Leadership
Team. Day-to-day management is carried out
by Global Product Supply Business Support
and EHS in coordination with local EHS site
managers.
Actions
E5-2
Waste management is embedded in site-
level operations, ensuring compliance with
local legal requirements and continuously
assessing opportunities for recycling and
reuse throughout the product lifecycle. In
2025, efforts focused on operational waste,
by developing the global waste policy and
preparing site-level action plans for 2026.
Over the coming years, ALK plans to implement
waste management requirements in supplier
selection.
Targets
E5-3
To support the global waste policy objective,
ALK's focus in 2025 has been on improving its
mapping of waste types and fractions in line
with the EU waste hierarchy and the ESRS,
and so the company has not yet established a
target.
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Annual Report 2025 54Environmental information
29%
18%
7%
46%
Waste
E5-4,5
Total waste generated in 2025 was 2,096
tonnes (2024: 2,882). 75% (2024: 81%) of total
waste was either recycled or prepared for
reuse. Waste reused or recycled decreased
to 1,575 tonnes (2024: 2,337), largely due to
a reduction in organic material such as hay
(non-hazardous waste prepared for reuse).
The waste incinerated or landfilled remained
stable.
2025 2024
Unit Hazardous
Non-
hazardous Total Hazardous
Non-
hazardous Total
Waste reused or recycled
Preparation for reuse Tonnes 32 932 964 24 1,384 1,408
Recycling Tonnes 162 450 612 221 708 929
Tonnes 194 1,382 1,576 245 2,092 2,337
Waste incinerated or landfilled
Incineration Tonnes 162 222 384 158 245 403
Landfill Tonnes - 136 136 1 141 142
Tonnes 162 358 520 159 386 545
Non-recycled waste % 46% 21% 25% 39% 16% 19%
Total waste generated Tonnes 356 1,740 2,096 404 2,478 2,882
Waste
Preparation for reuse
Recycling
Incineration
Landfill
Operational waste can be separated into:
1. Pharmaceutical waste streams, which include
chemical waste and medical waste (residues from APIs, solvents,
and reagents used in production processes)
product-related material (plastics, metals, glass, and
transportation boxes).
2. Agricultural waste streams, which come from ALK's source
materials used in the allergen production, and include
mite media (residual materials from the cultivation and
extraction of allergenic source materials)
organic materials (plant-based or biological substances such as
hay and wood trimmings).
ALK does not currently gather global data on material resource inflows, or on the rate of recyclable content, and does not at this stage have data in place to provide a reliable estimate.
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EU Taxonomy
Under Article 8(1) of the Taxonomy regulation
(EU) 2020/852 and further detailed in Annex I of
the Disclosure Delegated Act (EU) 2021/2178,
ALK is obligated to report on the sustainability
profile of its Turnover, Capital Expenditure
(CapEx) and Operating Expenditure (OpEx). This
process involves evaluating ALK's economic
activities against those enumerated in the
delegated legislation of the EU Taxonomy (i.e.
eligibility assessment), identifying ALK's eligible
Turnover, CapEx and OpEx, and finally assessing
compliance with the Substantial Contribution
Criteria (i.e. alignment assessment). The findings
from both the eligibility and alignment assess-
ments are encapsulated in key performance
indicators (KPIs) for Turnover, OpEx and CapEx.
ALK had adopted the simplified templates for
EU Taxonomy reporting, but has not imple-
mented the 10% materiality threshold.
For a full overview of ALK's taxonomy eligible activities,
see the tables in the appendix EU Taxonomy on pages
83-84.
Eligibility and alignment
In 2025, ALK has identified 97.4% turnover
(2024: 98.0%), 71.4% CapEx (2024: 18.7%),
and 53.1 % OpEx (2024: 57.9 %) eligibility.
CapEx eligibility returned to previous years'
level, after the Neffy
®
investment prepayment,
which temporarily decreased the share of
eligible activities in 2024.
ALK has not claimed EU taxonomy alignment
for any eligible activities as it cannot be docu-
mented. A climate risk assessment has been
initiated in 2025.
Turnover
ALK has identified the following eligible turn-
over activities:
PPC 1.1, manufacture of active pharmaceu-
tical ingredients (API) or active substances:
Turnover related to manufacture of allergen
extracts for use in the diagnosis of specific
allergies, for instance in skin prick tests
(0.3% of turnover).
PPC 1.2, manufacture of medicinal products:
Turnover stemming from the production
of allergy immunotherapy treatments and
adrenaline pens (97.1% of turnover).
CapEx
ALK has identified the following eligible CapEx
activities:
PPC 1.2, manufacture of medicinal products:
Capital expenditures related to the manufac-
turing of allergy immunotherapy treatments
and adrenaline pens (41.0% of CapEx).
CMM 7.3, installation, maintenance and
repair of energy efficiency equipment: In 2025
ALK initiated Phase 2 of Decarbonisation
project in France that involves the upgrade of
the Purified Water System and reduction of
energy consumption (1.1% of CapEx).
CCM 7.5 Installation, maintenance and
repair of instruments and devices for meas-
uring, regulation and controlling energy
performance of buildings: In 2025, a minor
portion of ALK’s CapEx was related to the
ongoing installation of metering equipment
in Denmark to monitor water and electricity
consumption (0.0% of CapEx).
CCM 7.6, installation, maintenance, and
repair of renewable energy technologies: In
2025 ALK continued Phase 1 of Decarboni-
sation project related to the installation of an
electrified boiler in France replacing a boiler
running on natural gas (1.3% of CapEx).
CCM 7.7, acquisition and ownership of build-
ings: Projects related to investments and main-
tenance of ALK’s buildings (27.9% of CapEx).
OpEx
ALK has identified the following eligible OpEx
activities:
PPC 1.2, manufacture of medicinal products:
OpEx related to the manufacturing of allergy
immunotherapy treatments and adrenaline
pens (45.1% of OpEx).
CCM 6.5, transport by motorbikes, passenger
cars and light commercial vehicles: Leased
vehicles (8% of OpEx).
Proportion of turnover, CapEx, OpEx from products or services associated with Taxonomy-eligible or Taxonomy-aligned economic activities - disclosure covering year 2025
Financial year 2025
Breakdown by environmental objectives of
Taxonomy aligned activities
KPI
(1)
Total
(2)
Propotion of
Taxonomy
eligible
activities
(3)
Taxonomy
aligned
activities
(4)
Proportion
of Taxonomy
aligned
activities
(5)
Mitigation
Climate
Change
(6)
Adaptation
Climate
Change
(7)
Water
(8)
Economy
Circular
(9)
Pollution
(10)
Biodiversity
(11)
Proportion
of enabling
activities
(12)
Proportion of
transitional
activities
(13)
Not assessed
activities
considered
non-material
(14)
Taxonomy
aligned activi-
ties in previous
financial year
2024
Proportion
of Taxonomy
aligned activi-
ties in previous
financial year
2024
DKKm % DKKm % % % % % % % % % % DKKm %
Turnover 6.312 97.4% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0 0.0%
CapEx 360 71.4% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0 0.0%
OpEx 368 53.1% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0 0.0%
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Accounting policies – Environmental information
The numeric datapoints reported are verified through
internal controls, analysis, benchmarks, and regular
business meetings. External auditors provide limited
assurance on 2024 and 2025 metrics. The metrics
are not validated by another external body, with the
exception of the science-based target metrics which
are approved by the Science Based Targets initiative
(SBTi). N/A is used when data was not available at the
time of the reporting and could not be retrieved.
Coverage
Environmental data covers ALKs production sites
in the USA (Post Falls and related farms, Port Wash-
ington, Oklahoma City, Luther and Plainville), Denmark
(Hørsholm), Spain (Madrid), and France (Vandeuil and
Varennes). Sales offices located across the globe are
excluded from reporting on energy, pollution, water,
substance of concerns and waste data due to the low
materiality of their environmental footprint.
From 2024 onwards, in accordance with ESRS
requirements, data from sales offices are included
in greenhouse gas (GHG) emission reporting (
see
GHG emissions on pages 48-49). However, the
reduction target for scope 1 and 2 remains focused
primarily on production sites, as validated by SBTi.
Climate Change
(incl. significant estimate for scope 3 category 1
Purchased goods and services)
Energy consumption and mix
Energy consumption for operations is measured as
consumption of electricity, heat and fuel.
Energy consumption from fossil sources includes fuel
consumption from crude oil, petroleum products,
natural gas, and the use of purchased or acquired
electricity, heat, steam, or cooling. No other fuel
sources are used.
“Fuel consumption from crude oil and petroleum
products” consists of diesel, gas oil and propane.
Energy consumption is based on meter readings
and/or invoices at individual production sites. While
the majority of the data is derived from actual data,
some estimations are applied to a minor portion of
the fuel consumption data:
Fuel consumption from diesel backup generators
is primarily based on estimates.
For some collecting vehicles (leased or owned
company vehicles used to collect source mate-
rials) at USA production sites, fuel consumption is
estimated where odometers are aged or damaged
and mileage data cannot be documented.
Heat consumption comes from district heating in
Denmark, and the supplier provides the breakdown
between fossil and renewable sources.
Electricity production is sourced 100% from renewable
power, primarily through Renewable Electricity Certif-
icates (RECs). The share of renewable energy used at
production sites is reported according to the market-
based method of the GHG Protocol scope 2 Guideline.
Conversion factors for measuring units are sourced
from well-established and authoritative references,
and are consistent across sites and contexts, ensuring
reliability and uniformity in reporting and calculations.
GHG emissions
GHG emissions are prepared in accordance with the
GHG Protocol. All greenhouse gases are included
and GHG emissions are reported in metric tonnes of
carbon dioxide equivalent.
When available and recent, source and supplier-spe-
cific emission factors or local grid emission factors
are used, reflecting local energy mixes and regional
characteristics. When such data are unavailable
or outdated, general emission factors are utilised.
The specific databases used in these instances are
disclosed below.
Scope 1
Direct energy consumption
GHG emissions from direct energy consumption are
based on fuel consumption reported in
Energy
consumption and mix on page 49 and cover diesel,
gas oil, natural gas and propane.
When local emission factors are unavailable, general
CO
2
emission factors from UK Government GHG
Conversions Factors and Environmental Protection
Agency (EPA) are applied. These authoritative
sources provide comprehensive data covering a wide
range of activities and energy sources.
Emissions from collecting vehicles (leased or owned
company vehicles used to collect source materials)
are based on mileage and apply EPA annual emis-
sions factors.
Company fleet
Company fleet emissions are calculated from actual
or contracted annual mileage. Average passenger
vehicle emission factors are taken from UK Depart-
ment for Environment, Food & Rural Affairs (DEFRA).
December data is estimated using the reporting year
monthly average.
Refrigerants
For refrigerants listed in the GHG Protocol, leakage
from cooling systems is included in Scope 1, based on
refrigerant quantities using emissions factors from
UK Government Conversion Factors.
Scope 2
Production sites
Scope 2 emissions comprise CO
2
e emissions from
purchased electricity and heat (district heating), as
disclosed in
Energy consumption and mix on page
49.
Scope 2 location-based emissions are calculated
based on average energy generation emission factors
for defined locations, while scope 2 market-based
emissions are calculated based on emissions calcu-
lated from specific energy purchase contracts and
therefore consider renewable energy purchase certifi-
cates.
When local emission factors are unavailable, general
CO
2
emission factors from UK Government GHG Conver-
sions Factors and EPA GHG Emissions Factors are used.
ALK does not have bundled certificates. All electricity
consumption is covered by 100% unbundled renewable
energy certificates, while none of its district heating
consumption is covered by unbundled certificates.
Sales offices
GHG emissions from sales offices are estimated
based on office area (square meters) multiplied by
a world-average office energy use factor and coun-
try-specific emission factors.
Scope 3
All scope 3 emissions are calculated based on data
covering January-December 2025, except category
3, 4 and 12 where November and December are
estimated based on average consumption in the
reporting year.
Scope 3 categories 8, 10, 11, 13, 14, and 15 from the
GHG Protocol are excluded as ALK has no emissions
associated with those categories.
Purchased goods and services (significant estimate)
based on spend, using emission factors from the
Comprehensive Environmental Data Archive (CEDA).
Capital goods
based on spend data for industrial
machinery owned and operated by ALK, multiplied by
emission factors from CEDA.
Fuel and energy
related activities of upstream
transmission & distribution losses of fuels, electricity
and district heating consumed by ALK which are
not included in scope 1 and scope 2, using emission
factors from DEFRA.
Upstream transportation and distribution
based on
a mix of spend-based emission factors from CEDA
Management's
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Pollution
Water
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ecosystems
Resource use and
circular economy
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information
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information
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Financial
statements
Annual Report 2025 57Environmental information
and primary emissions from certain distribution
providers. Well-to-tank emission factors are provided
by DEFRA.
Waste generated in operations
based on DEFRA,
dependent on material type, treatment type, mate-
rial location and material weight.
Business travel
based primary activity data from
service providers using well-to-wheel flight emissions
from DEFRA.
Employee commuting
using Quantis emission factors
based on the average number of full-time equivalent
employees in the reporting year, with well-to-tank
emission factors from DEFRA.
Downstream transportation and distribution
based
on spend-based emission factors from CEDA on truck
transportation.
End-of-life treatment of sold products
based on esti-
mates for materials used in products, using DEFRA
emission factors for material type, country of distri-
bution, assumed treatment type and weight.
SBTi targets
Scope 1+2 target
GHG emission reduction targets follow SBTi guidelines,
covering all production sites. Emissions from sales
offices are excluded, as they account for less than 5%
of scope 1 and 2 GHG emissions. The achieved reduc-
tion is calculated against a 2022 baseline for scope
1 and 2 emissions from production sites, ensuring
consistency in the scope over the years.
Suppliers with science-based targets
The metric measures scope 3 emissions associated
with suppliers that have SBTi targets. The scope 3
categories included in this metric are purchased
goods and services, capital goods, upstream trans-
portation and distribution, business travel and down-
stream transportation and distribution. The denom-
inator is calculated as the total scope 3 emissions
from those categories. To determine the numerator,
suppliers with validated targets or active commit-
ments are identified through the SBTi dashboard at
the end of the financial year. The Supplier Tracker List
is used to document suppliers with validated targets.
Annual percentage target
The metric “Annual % target / Base year” is calculated
by dividing the SBTi target (i.e, -42% and 80%) by
the number of years between the target year and the
base year (respectively, 8 and 6).
Pollution
SoCs and SVHCs are reported as purchased quan-
tities by all production sites, covering both product
supply and research and development activities,
based on invoices or delivery notes from vendors.
Quantities of SoCs and SVHCs that leave ALK’s facili-
ties are not reported, as the estimate would be equal
to amounts procured.
At each site, comprehensive lists of SoC chemicals
are created by using the internal chemical manage-
ment system. SoC chemicals are labelled with one or
more Hazard-statements (H-statements), according
to the Classification, Labelling and Packaging of
chemicals (CLP Regulation) in EU. For production
sites in the USA, where H-statements are not avail-
able, GHS hazard statements (defined by OSHA) are
translated into H-statements to determine which
chemicals are SoCs or SVHCs.
Water
(incl. significant estimate for irrigation as well as
water reused and recycled)
Water consumption
Water is categorised into water for domestic use
(drinking water, sanitary water, and water for
production) and water for irrigation, which is used for
cultivating source materials. For irrigation, the use of
estimates is considered significant.
Water consumption is reported in m
3
based on meter
readings and/or invoices at individual production
sites. When meter readings or invoices are unavail-
able, estimation-based water consumption is used to
calculate water consumption:
Water irrigation for leased land at Post Falls (USA)
farmland is estimated by multiplying the leased
area by the water consumption intensity factor (m³/
acre) derived from measured data on company
owned land.
Water usage at leased facilities in Plainville and
Port Washington (USA) production sites is esti-
mated based on square footage occupied by ALK,
as stated in the leasing contract, relative to the
total square footage of the building.
Water storage
ALK does not store water.
Water consumption in areas of high-water stress
This corresponds to water consumption at ALK’s
Madrid (Spain) production site.
Water reused and recycled
Only one leased site in the USA currently reuses water,
as part of a water reclamation program overseen by
the DEQ (Department of Environmental Quality).
Resource use and circular economy
Waste is reported and categorised between treat-
ment methods at site level, based on invoices
received from waste vendor recipients. Operational
waste was either reused, recycled, incinerated, or
sent to landfill, with no other recovery or disposal
methods used.
Some estimates are used to calculate waste:
General solid waste at Luther and Plainville (USA)
production sites is estimated based on the pickup
cycles reported by the waste vendor for each
quarter.
For the leased location at 2 Channel at Port Wash-
ington (USA) production site, general solid waste
is not managed internally. Estimation is therefore
based on the average number of garbage bags
collected per day.
For some USA production sites and Madrid (Spain)
production site, certain types of waste are esti-
mated based on the number of pickups reported
by the waste vendor. These estimates are either
supported by actual waste weight measurements
collected over a defined period and applied as
fixed standards for the waste type, or, when actual
weights are unavailable, derived using conversion
factors published by governmental authorities.
The actual weights of containers or dumpsters are
measured at local production sites over a defined
period.
By default, waste is reported in accordance with the
waste hierarchy of EU waste polices and legislation,
which is described in the EU waste framework direc-
tive (Directive 2008/98/EC).
For production sites in Europe, when there is a
difference between EU and national legislation,
ALK follows the national legislation. Waste types
are categorised by the respective waste vendor
according to the national legislation.
For production sites in the USA, estimation-based
waste is calculated using conversion factors
published by the US EPA.
Intensity calculations
Net revenue amounts are derived from ALK's total
group turnover of the consolidated financial state-
ments (note 2.1, page 94).
Intensity calculations are reported as unit / annual
revenue in million DKK. GHG intensity is calculated
using total emissions (scope 1, 2 and 3) on loca-
tion-based and market-based methods.
All revenue falls under NACE Section C: Manufac-
turing, Division 21: manufacturing of basic pharma-
ceutical products and pharmaceutical preparations
according to Commission Delegated Regulation (EU)
2022/1288. Manufacturing is a high climate impact
sector.
Management's
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statement
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information
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information
Climate change
Pollution
Water
Biodiversity and
ecosystems
Resource use and
circular economy
EU Taxonomy
Accounting policies
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information
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information
Governance
information
Appendix
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statements
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Social information
Own workforce
S1
ALK is focused on fostering the wellbeing,
professional growth and inclusivity of its
employees. This helps ALK to attract and retain
the key competences needed for its operations
worldwide. By prioritising the development and
engagement of employees, ALK ensures that
staff are empowered, motivated and equipped
to contribute to the organisation’s mission to
improve the lives of people with allergy all over
the world.
This section outlines general information on
ALK’s workforce, and details ALK’s strategy
on competency development, inclusive culture
and health and safety.
General information
Policies
S1-1
ALK supports the UN Guiding Principles on
Business and Human Rights and is a signatory
to the UN Global Compact. Commitments to
health, safety, and human rights are integrated
into ALK’s Code of Conduct, which applies to
all employees. The Code of Conduct explicitly
prohibits any involvement in child or forced
labour.
The Code of Conduct is described in detail in Corporate
culture on pages 72-73.
Processes for engagement
and remediation
S1-2, 3
Through engagement with workers’ coun-
cils, a global sounding board and the annual
engagement survey, ALK fosters a culture
of open communication, engagement and
collaboration.
Workers’ councils are established at all Euro-
pean sites where legally required, providing
a forum for employees and management to
discuss various topics, ranging from compet-
itiveness to employee engagement. Council
meetings are held several times a year, with
engagement tailored to the topic and local
legal requirements. In the USA and China,
dialogues are facilitated through the People &
Organisation departments.
The annual global employee engagement
survey is a further key tool for direct engage-
ment with all employees and for gathering
feedback. This year's participation rate
remained high at 94% (2024: 95%). The overall
engagement score increased to 8.6 (2024:
8.3), positioning ALK in the top 5% against the
international healthcare benchmark for the
second year in a row.
The ELT reviews company-wide results and
integrates relevant actions into the People &
Organisation roadmap. At function and team
levels, the results are analysed to identify
specific challenges and opportunities and
implement tailored actions.
The sounding board, consisting of leaders
across the organisation, provides advice and
feedback to People and Organisation on their
ideas, thoughts and decisions.
All employees can raise concerns through the whis-
tleblower platform ALK Alertline, which is described in
detail in Whistleblowing and anti-corruption system on
page 74.
Management's
review
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statement
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informationinformation
Environmental Environmental
informationinformation
Social Social
informationinformation
Own workforce Own workforce
Workers in the value Workers in the value
chainchain
Consumers and Consumers and
end-usersend-users
Accounting policies Accounting policies
– Social information– Social information
Governance Governance
informationinformation
AppendixAppendix
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statements
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Social information
Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Competence development
As ALK’s business develops and new competences
are required, employees need to continually develop
their skills. Individual development plans, linked to job
content and performance goals, promote continuous
learning and skill building, ensuring employees can
meet current and future job expectations.
Potential
negative
impact
Competence development
Processes to remediate
S1-3
ALK has a dedicated team within Global People
and Organisation responsible for managing
global development programmes and related
employee development processes, ensuring
alignment with future business needs.
As part of the global People Performance
process, all ALK employees must draw up a
personal development agreement with their
leader. These plans are tailored to the individu-
al’s role, career stage and performance goals,
supporting continuous learning and employ-
ability. The 70–20–10 learning model is used:
70% on-the-job learning, 20% peer learning,
and 10% formal training. Development agree-
ments are reviewed and updated annually,
and this process applies exclusively to ALK
employees. Leaders and employees are jointly
responsible for ensuring that skills match
current and future job requirements.
Actions
S1-4
In 2025, ALK updated its People Performance
process to reflect results, behaviours and
overall performance. Insights from this process
will inform development programmes and
individual development agreements.
Recognising the growing importance of digital
competencies, ALK also identified a need to
strengthen AI skills across the organisation.
A global training programme was launched
in 2025, offering both basic and advanced
modules for all leaders and employees. The
programme was well received, with more than
1,000 participants, and demonstrates ALK’s
commitment to equipping employees for future
needs.
To support ongoing leadership development,
ALK continued the rollout of the Leading with
Impact programme across the organisation,
focusing on critical leadership capabilities as
well at its ASPIRE talent initiative.
Training and skills development
S1-13
Unit 2025 2024
Participation in performance reviews
Male % 93% 91%
Female % 91% 94%
Chooses not to self identify % 67% 100%
Number of performance reviews per employee # 1:1 1:1
Total participation % 92% 93%
Participation in performance
reviews
92%
Management's
review
Sustainability
statement
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information
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information
Social
information
Own workforce
Workers in the value
chain
Consumers and
end-users
Accounting policies
– Social information
Governance
information
Appendix
Financial
statements
Annual Report 2025 60Social information
Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Inclusive culture
At ALK, fostering an inclusive culture is essential
for effectively addressing the diverse needs of
patients and partners. A lack of inclusivity may hinder
employees' ability to thrive and perform, which in turn
can limit ALK’s potential for innovation.
Potential
negative
impact
Inclusive culture
Policies
S1-1
In addition to the Code of Conduct, which
addresses human rights and harassment,
ALK’s Diversity & Inclusion (D&I) policy aims to
eliminate discrimination and promote equal
treatment and opportunities for all employees.
It sets out ALK's ambition to create an inclu-
sive work environment that fosters a sense of
belonging, in which different perspectives,
abilities, talents and experiences are able to
contribute equally. The policy applies to all ALK
employees. The most senior level accountable
for implementing the policy is the ELT, which
receives regular reports on the company-wide
diversity performance.
While ALKs D&I policy prohibits discrimina-
tion on grounds such as age, gender, race,
ethnicity, religion, sexual orientation, disability
and other characteristics (including work and
life perspectives), it does not include specific
commitments to include people from particu-
larly at-risk or vulnerable groups.
ALK tracks employees’ perceptions of D&I and
their sense of psychological safety via the
annual employee engagement survey. In 2025,
the overall perception of diversity in ALK rose to
8.4 (2024: 8.2) and stands 0.3 points above the
industry benchmark.
Actions
S1-4
ALK’s Global People & Organisation function is
responsible for the D&I strategy and activities.
In 2025, the D&I strategy was updated to
further integrate diversity and inclusion into
ALK’s business strategy and operations, with
a focus on three strategic priorities: fostering
inclusive environments, achieving gender
balance by ensuring equality and representa-
tion across all levels, and cultivating a global
workforce by attracting international talent,
increasing nationality diversity, and embracing
multiple cultural perspectives.
Key initiatives include leadership training on
inclusivity and unconscious bias, analysis of
progression barriers for senior female leaders,
and the development of a more equitable,
global recruitment process.
Targets
S1-5
ALK has set a target to have at least 40% of
the underrepresented gender in the ELT and
their direct reports in managerial positions,
by 2028. ALK has not involved its own work-
force or workers’ representatives in the target
setting. The development is tracked quarterly
as a part of the internal reporting.
Management's
review
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end-users
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Diversity and remuneration
S1- 9, 16
Executive Leadership Team and their direct
reports in managerial positions Unit 2025 2024
Male Headcount 34 26
Female Headcount 21 21
Headcount 55 47
Percentage of underrepresented gender % 38% 45%
Diversity metrics Unit 2025 2024
Age distribution
Under 30 years old Headcount 301 N/A
30-50 years old Headcount 1,539 N/A
Over 50 years old Headcount 871 N/A
Headcount 2,711 2,812
Gender distribution
Male Headcount 999 1,065
Female Headcount 1,709 1,743
Chooses not to self identify Headcount 3 4
Headcount 2,711 2,812
Percentage of females in total workforce % 63% 62%
Remuneration metrics Unit 2025 2024
CEO annual compensation ratio Times 33 33
Unadjusted gender pay gap
1
% 23% 20%
Adjusted gender pay gap % 3% 3%
1
In 2025, the unadjusted gender pay gap has been revised to include additional components such as bonuses, sales incentives
and LTI grants. The 2024 gender pay gap has been restated to reflect the additional components (previously 17%).
In 2025, the percentage of underrepresented
gender in the ELT and their direct reports with
managerial responsibility decreased to 38%
(2024: 45%), falling below the 40% target.
This change reflects adjustments at ALK’s top
management level, with Europe and North
America now elevated to ELT representation.
This regional reorganisation is a key step in
evolving ALK’s operating model to support the
Allergy
+
strategy and enhance commercial
execution.
This year, ALK reported the adjusted gender
pay gap for the first time, using weighted
average pay data that accounts for differ-
ences in country and grade. When these
factors are considered, most of the unad-
justed gap is explained, leaving a residual
adjusted gender pay gap of 3% (2024: 3%).
Action plans to strengthen equitable rewards
for all employees even further are guided by
the requirements of the EU Pay Transparency
Directive.
38%
of underrepresented gender in the Executive
Leadership Team and their direct reports in
managerial positions
Management's
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end-users
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– Social information
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information
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statements
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Workplace accidents
Employees - particularly those in farming and produc-
tion – may be at risk of workplace accidents that can
cause physical injury and harm mental wellbeing.
Actual
negative
impact
Health and safety
Policies
S1-1
Health and safety management is a core
priority for ALK. The Code of Conduct sets out
ALK’s commitment to preventing workplace
incidents, fostering a strong safety culture,
and promoting both physical and mental well-
being across the organisation. ALK adheres to
national legislation and regulatory health and
safety requirements in all countries in which it
operates and complies with OSHA standards
in the USA.
The Code of Conduct is described in detail in Corporate
culture on pages 72-73.
Actions and processes for remediation
S1-3, 4
ALK promotes a strong safety culture by
engaging employees in health and safety prac-
tices and fostering shared responsibility. Risk
assessments are conducted at all production
sites to identify hazards, implement preventive
measures, and evaluate their effectiveness,
with employee input playing a key role. In the
event of an accident or a near miss, a risk eval-
uation is conducted and relevant actions are
taken accordingly to prevent any recurrence.
Workplace injuries are recorded and monitored
in line with legal requirements, including OSHA
standards in the USA, to ensure compliance
and continuous improvement. Employees are
encouraged to report unsafe conditions, and
regular training supports awareness and safe
work practices across all operations.
ALK decreased its total work-related accidents
to 78 (2024: 112). ALK had 4 accidents with lost
time absence ordinated by a medical profes-
sional in 2025 (2024: 6). This resulted in an
accident rate of 1.0 (2024: 1.5), also commonly
referred to as Lost Time Injury Frequency Rate
(LTIFR).
For S1-17, see Metrics on page 74.
Health and safety
S1-14
Unit 2025 2024
Employees covered by health & safety
management system % 78% 74%
Work-related accidents # 78 112
Work-related accidents with absence # 4 6
Work-related accidents with absence rate 1.0 1.5
Fatalities as a result of work-related incident # - -
Work-related accident rate
1.0
2024 2025
6
4
1.5
1.0
Work-related accidents with absence
Work-related accidents with absence
Lost Time Injury Frequency Rate (LTIFR)
Management's
review
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statement
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end-users
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statements
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General metrics
Employee characteristics
S1-6
Number of employees per country Unit 2025 2024
Europe
Denmark Headcount 969 942
France Headcount 363 357
Germany Headcount 143 137
Poland Headcount 106 96
Spain Headcount 391 364
Other Europe Headcount 189 170
Headcount 2,161 2,066
North America
USA Headcount 503 547
Other North America Headcount 30 21
Headcount 533 568
International markets
International markets Headcount 17 178
Headcount 17 178
Total number of employees Headcount 2,711 2,812
Employee turnover Unit 2025 2024
Employee turnover Headcount 322 463
Rate of employee turnover % 12% 17%
2025 2024
Employees by contract type and gender Unit Male Female
Chooses not to
self identify Total Male Female
Chooses not to
self identify Total
Permanent employees Headcount 970 1,640 3 2,613 970 1,601 3 2,574
Temporary employees Headcount 29 69 - 98 95 142 1 238
Total employees Headcount 999 1,709 3 2 ,711 1,065 1,743 4 2,812
Non-guaranteed hours employees Headcount 12 19 - 31 15 20 - 35
ALK employs 2,711 employees (2024: 2,812), of
whom 96% (2,613) are permanently employed
(2024: 2,574). The employee turnover was 12%
in 2025 (2024:17%), of which 172 (2024: 283)
employees left voluntarily and 150 (2024: 180)
involuntarily.
The decrease in number of employees primarily
relates to the transfer of ALK’s employees
in China to the biopharmaceutical company
GenSci as a part of the partnership agreement
as well as other organisational adjustments
relating to the implementation of the Allergy
+
strategy.
See Incorporation by reference on page 77.
Employee turnover
12%
Management's
review
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statement
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information
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chain
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end-users
Accounting policies
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information
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statements
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Human rights and Health and Safety issues in
the value chain
ALK works with suppliers worldwide, including in
regions and sectors where human rights risks and
weaker health and safety protections may exist. Value
chain workers - particularly those handling hazardous
substances, working in transport, or managing
hazardous waste - may face elevated health and
safety risks.
Potential
negative
impact
Workers in the value chain
S2
ALK collaborates with suppliers and partners
globally as a core part of its strategy and busi-
ness model. ALK recognises that its activities
may indirectly affect human rights and health
and safety, and is committed to upholding high
standards across the value chain.
ALK has identified high-level potential material
impacts on workers in the value chain, and
recognises the need for continuous analysis
to pinpoint activities where workers may
face greater risk of harm. While most of ALK’s
suppliers are EU-based, where robust law
enforcement reduces the risk of child labour,
ALK remains vigilant in assessing human rights
risks across all geographies.
The most significant groups of supplier
employees at risk of human rights and health
and safety violations are:
Workers in upstream production units. They
could be exposed to hazardous substances,
including chemicals used in the manufacture
of pharmaceutical ingredients and consum-
ables. Key risks in this area include chemical
exposure, operational hazards and ergo-
nomic risks.
Workers involved in downstream transporta-
tion. They face the risk of vehicle accidents,
which can result in serious injuries or fatal-
ities. These include risks during loading,
unloading and transit.
Workers handling hazardous waste. They
can encounter harmful chemicals that pose
significant health risks, including chemical
burns, respiratory issues and toxic exposure.
Policies
S2-1
ALK’s Third-Party Code of Conduct outlines the
standards of behaviour that ALK expects from
all third parties globally when it comes to busi-
ness conduct and treatment of employees.
The Third-Party Code of Conduct is aligned with
the Ten Principles of the United Nations Global
Compact and follows the UN Guiding Principles
on Business and Human Rights (UNGP), as well
as applicable laws, regulations, standards
and labour agreements.
Key areas covered include health and safety,
animal welfare, anti-corruption, environ-
mental practices, working conditions, human
rights (including child and forced labour,
anti-discrimination and fair pay), interaction
with healthcare professionals and patient
organisations. The policy does not specifically
mention human trafficking.
The Third-Party Code of Conduct embeds the
expectation that ALK and its partners will
respect human rights throughout the value
chain and extends beyond legal compliance
to require continuous improvement and
awareness among employees, supporting the
UNGP’s emphasis on due diligence.
Requirements for training, awareness, and
ensuring the standards are implemented and
cascaded to further Third Parties reflect the
UNGP’s approach to integrating human rights
across business relationships.
Any breaches of the standards in the ALK
Third-Party Code of Conduct can be reported
through the whistleblower platform.
The Third-Party Code of Conduct is an integral
part of ALK's GxP (good practice) supplier
agreements. All new suppliers must commit
to the Code as a prerequisite for collaboration
with ALK. The Chief Financial Officer is the most
senior-level executive accountable for the
implementation of ALK’s Third-Party Code of
Conduct.
In addition to the Third-Party Code of Conduct
covering human rights impacts, ALK also
adheres to the UK Modern Slavery Act and
publishes an annual statement of compliance.
Management's
review
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statement
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information
Environmental
information
Social
information
Own workforce
Workers in the value
chain
Consumers and
end-users
Accounting policies
– Social information
Governance
information
Appendix
Financial
statements
Annual Report 2025 65Social information
Processes for engagement
S2-2
While ALK does not have a formal process
in place to engage with workers in the value
chain on impacts, its sustainable procure-
ment programme seeks to ensure that poten-
tial negative impacts on these workers are
addressed.
The Senior Vice President (SVP), Global
Procurement bears the overall responsibility
for the supplier engagement programme.
Processes for remediation
S2-3
Value chain workers can raise concerns
through ALK’s whistleblowing platform, ALK
Alertline, which can be accessed via ALK’s
website. No complaints involving workers in
the value chain were substantiated in 2025.
ALK does not currently have any mechanisms
to assess whether these workers are aware of
or trust ALK Alertline.
Actions
S2-4
ALK prioritises reputable suppliers that uphold
high standards, reducing the risk of serious
breaches of labour or compliance standards.
Long term contracts provide financial stability
and encourage sustained commitment to
responsible working conditions, as stable
revenue enables suppliers to invest in infra-
structure, training and safety.
Through a partnership with an external evalu-
ation platform, ALK assesses environmental,
labour, and human rights risks. During 2025,
ALK assessed over 1,400 of its suppliers,
covering 97% of the procurement spend. The
suppliers assessed are considered strategic
to ALK and consist of both direct suppliers who
supply materials included in ALK's products
and indirect suppliers who supply products or
services to support ALK’s business operations.
While no suppliers were identified as very high
risk from an ESG perspective, ALK will continue
to further its due diligence programme and
potentially include additional categories going
forward. Potential necessary actions to reme-
diate any negative impacts will be discussed
at the regular business relationship meetings.
No severe human rights issues and incidents
connected to ALK’s upstream and downstream
value chain were reported in 2025 ( see
Metrics on page 74).
Targets
S2-5
ALK continuously assesses its suppliers for
potential human rights and health and safety
risks. To date, no suppliers have been identi-
fied as very high risk in the ESG assessment.
ALK has therefore not identified a need for
specific targets related to formal engagement
with workers within the value chain.
Management's
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information
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information
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Workers in the value
chain
Consumers and
end-users
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– Social information
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information
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Financial
statements
Annual Report 2025 66Social information
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Allergy treatment
Helping more people with allergies is at the core of
ALK’s Allergy
+
strategy. ALK’s allergy treatments
significantly improve patients' quality of life and
personal wellbeing by addressing a wide range of
allergies, including potentially life-threatening condi-
tions like anaphylaxis and insect venom reactions.
Actual
positive
impact
Barriers to access
Allergy treatment must be prescribed by a healthcare
professional (HCP), and is often not prioritised by
healthcare systems, creating barriers for patients.
Potential
negative
impact
Product safety and quality
Any disruptions in ALK's processes to manage product
safety and quality could lead to patients taking unsuit-
able medication or forgoing beneficial treatments.
Potential
negative
impact
Affordability
Inequality in access to health is a systemic problem
among and within countries. People living with aller-
gies might not be able to afford allergy treatment. This
would have long-lasting negative effect on their health
and wellbeing.
Actual
negative
impact
Consumers and end-users
S4
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Innovation
By introducing new products through ongoing drug
discoveries and clinical trial approvals, ALK can further
expand market opportunities and support even more
patients.
Opportunity
Climate change and respiratory health
Climate change threatens respiratory health by
extending pollen seasons, increasing airborne aller-
gens and promoting mould growth. The expands the
potential market size for ALK, as more individuals have
prolonged and intensified allergy symptoms.
Opportunity
Allergy is one of the most common types of
chronic disease globally and it has a profound
impact on people’s lives. For more than 100
years, ALK has been at the forefront of long-
term allergy treatment and is dedicated to
offering a wide range of treatments, products
and services to meet the unique needs of people
living with allergy, their families and doctors.
Allergy treatment is the core purpose of ALK’s
business model, and the activities to further the
positive impact and opportunities and to miti-
gate the negative impacts are an integral part
of ALK’s daily operations and Allergy
+
strategy.
For further details, see pages 12-17.
Consumers and end-users for ALK include both
healthcare professionals (such as general
practitioners, paediatricians, and allergolo-
gists), patients and caregivers. As a provider
of prescription medicines, ALK is committed
to ensuring that patients receive accurate and
accessible information leaflets to promote the
safe and effective use of their medication.
Impacts, risks and opportunities
SBM3
Management's
review
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statement
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information
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information
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information
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Workers in the value
chain
Consumers and
end-users
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– Social information
Governance
information
Appendix
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statements
Annual Report 2025 67Social information
Policies
S4-1
Access to Medicines policy
The Access to Medicines policy outlines the
company’s ambition to reach more patients
by focusing on three core principles: improving
quality of life through better treatment options
and earlier diagnosis, supporting healthcare
systems with training and education on allergy
care, and forming partnerships to enhance
access. The policy addresses the impacts
Allergy treatment and Barriers to access and
covers both patients and healthcare profes-
sionals.
In January 2025, the ELT reviewed the policy to
ensure continued alignment with the Allergy
+
strategy. The oversight, accountability and
responsibility for the implementation of ALK's
Access to Medicines policy rests with the
Board of Directors, which has delegated this
responsibility to the ELT.
Quality policy
ALKs global quality policy formalises the
company’s commitment to delivering high-
quality, safe and effective products and
services for people living with allergy. The
policy applies to all ALK operations, with the
objective to fulfil requirements while focusing
on simplicity and continuous improvement.
Oversight of the policy rests with the ELT,
with daily management delegated to Global
Quality. Quality objectives are reviewed at
least annually and are supported by all rele-
vant organisational levels within all areas
of the company. Accountability for quality is
embedded at every level: all employees are
expected to communicate transparently, and
learn from experience, while managers walk
the talk on quality.
As the pharmaceutical industry is heavily
regulated, human rights topics like the right to
health and informed consent in clinical trials
are already embedded in legislation. There-
fore, ALK does not have specific consumer
policies aligned with the UN Guiding Principles
on Business and Human Rights.
Processes for engagement
S4-2
ALK engages with patients through a compre-
hensive digital ecosystem of websites, social
media and dedicated applications that provide
educational content to the general public.
These platforms help raise ongoing aware-
ness of allergies, symptoms, their impact on
quality of life, and, in some markets, available
treatment options. ALKs digital channels
offer guidance on recognising symptoms
and on seeking appropriate medical advice.
The Global Marketing function is responsible
for expanding and maintaining ALKs digital
ecosystem.
For general information on stakeholder engagement,
see Interests and views of stakeholders on page 41.
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information
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statements
Annual Report 2025 68Social information
2024 2025 2026 2027 2028 2029 2030
5.0
3.1
2.6
Processes to remediate
S4-3
ALK ensures patient safety and product quality
through a robust, global pharmacovigilance
system designed to identify, assess, and
address side-effects and safety concerns,
covering both clinical trials and marketed
products.
Global Safety & Pharmacovigilance is respon-
sible for monitoring benefit-risk profiles of
ALK’s products, handling adverse event
reports, ensuring timely submissions to regula-
tory authorities worldwide and monitoring the
performance and compliance of ALK’s phar-
macovigilance system.
Patients are informed on how to report poten-
tial side effects in the leaflets for all products.
External stakeholders with a work-related
connection to ALK can raise their concerns
through the whistleblower platform ALK Alert-
line, which is described in detail in Whistle-
blowing and anti-corruption system on page
74.
Actions
S4-4
2025 marked significant milestones for ALK,
advancing the Allergy
+
strategy with major
launches and approvals for children and
adolescents. The house dust mite (HDM) tablet
is now approved for paediatric use in 30 coun-
tries and launched in 21 of them. The roll-out
of the tree pollen allergy tablet for children and
adolescents also started in 2025, based on
regulatory approvals from the EU and Canada.
Year-end, the tablet was approved for chil-
dren and adolescent use in 20 countries and
launched in 12 of these markets. With these
launches, ALK now offers four tablets, covering
80% of the most common respiratory allergies,
available for children, adolescents, and adults
in Europe and Canada.
In addition, the approval and launch of EUR-
neffy
®
, a needle-free nasal adrenaline spray,
in the UK and Germany has addressed impor-
tant gaps in anaphylaxis treatment for adults
and children. Under co-promotion agreement
with ARS Pharma, ALK is also responsible for
selling
neffy
®
to approximately 9,000 named
paediatricians in the USA. By eliminating the
fear, hesitation, and safety concerns associ-
ated with needle-based emergency medicine,
neffy
®
enables more patients to confidently
access timely, life-saving treatment during
acute allergic reactions.
Building on decades of pioneering the devel-
opment of standardised allergen extracts,
formulated as rapidly dissolving SLIT tablets,
ALK is expanding into new geographies and
patient groups and diversifying the portfolio
into food allergy, anaphylaxis, and adjacent
allergic diseases, with the ambition to lead
in each disease area. In 2025, the innovation
agenda advanced with phase 2 clinical trials
for the peanut SLIT tablet, with topline data
expected in 2026.
To reduce barriers to access, ALK expanded
digital education for healthcare professionals
Patients in treatment
S1-14
Unit 2025 2024
Patients in treatment million 3.1 2.6
Number of patients in treatment
Million patients (estimated)
through training sessions, targeted newsletters,
large multi-market webinars, and enhanced
healthcare professional portals offering prac-
tical tools and educational resources.
Targets
S4-5
ALK aims to help 5 million people with allergy
annually by 2030 to advance its positive impact
and opportunity. This aspiration covers ALK’s
downstream activities in the countries where
ALK operates ( see ALK's global presence on
page 7).
In 2025, the number of patients in treatment
reached an estimated 3.1 million (2024: 2.6
million), as a result of ALK's commercial activ-
ities.
Patients in treatment with ALK products
~3.1 million
Management's
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statement
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information
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information
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chain
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statements
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Accounting policies – Social information
The numeric data points reported are verified
through internal controls, analysis, benchmarks,
and regular business meetings. 2024 and 2025
metrics are limited assured by external auditors,
but they are not validated by another external
body. N/A is used when data was not available
at the time of the reporting, and could not be
retrieved.
Own workforce
Training and skills development
A regular performance review is defined as a
review based on criteria known to the employee
and his or her superior undertaken with the knowl-
edge of the employee at least once per year. The
review can include an evaluation by the employ-
ee’s direct superior, peers, or a wider range of
employees.
Employee engagement score is collected from a
survey conducted by a third party.
Diversity and remuneration metrics
CEO annual compensation ratio
CEO annual compensation is determined by the
annual total compensation of the CEO against the
median annual total compensation for all full-time
active (permanent and temporary) employees,
excluding the CEO. Annual total compensation
includes salary, bonus, allowances, pension, and
all one-time payments over the course of a year.
Gender pay gaps (significant estimates)
The metrics on gender pay gap are defined as the
difference of average pay levels between female
and male employees, expressed as a percentage
of the average pay level of male employees. The
metric includes all full-time active (permanent
and temporary) employees, including the CEO.
The pay levels are calculated using gross annu-
alised base pay, as well as other remuneration
components when reliable quality data are
available. This covers all one-time payments
made during the year (bonuses, sales incentives,
anniversary awards, etc.), LTI grants, and, for
Denmark, pension contributions and the so-called
fritvalgskonto
amounts. ALK is continuously
improving data coverage and quality to ensure
this metric is as accurate as possible.
The adjusted gender pay gap is calculated as a
weighted average across ALK’s grade levels and
across countries, using the same pay data.
Health and safety metrics
Work-related incidents are reported to Global
Environment, Health and Safety.
A work-related accident is defined as any
unplanned event that result in injury, with or
without absence. An accident with absence is
a work-related accident that results in time lost
from work ordered by a medical professional
person. The rate of work-related accidents is
calculated as Lost Time Injury Frequency Rate
(LTIFR), determined by the number of work-re-
lated accidents with absence per one million
working hours during a single financial year.
Fatalities are the number of employees who lost
their lives as a result of a work-related incident.
Employee characteristics
Workforce is defined as all ALK employees who
are on payroll as of 31
st
December 2025, both full-
time and part-time, as well as active and non-ac-
tive. The numbers are reported in headcount as
of end of reporting period and are extracted from
the HR systems.
Regions are broken down into Europe (Denmark,
France, Spain, Germany, Poland, Netherlands,
Sweden, Slovakia, United Kingdom, Austria, Swit-
zerland, Norway, Italy, Belgium, Czech Republic,
Finland, Ireland), North America (USA, Canada)
and International markets (China, Russia,
Jordan). Countries with less than 50 employees
are classified as “Other.For reporting by gender,
the following descriptions are used: ’Male’,
‘Female’, and ‘Employee chooses not to self-iden-
tify'.
Permanent employees are determined as
employees whose employment contract is without
a specified end-date. Temporary employees are
determined as employees whose employment
contract is with specified end-date. Non-guar-
anteed hours employees are determined as
employees employed by ALK without a guarantee
of a minimum or fixed number of working hours.
The employee may need to make themselves
available for work as required, but ALK is not
contractually obligated to offer the employee a
minimum or fixed number of working hours per
day, week, or month.
Employee turnover is defined by the number of
employees leaving ALK during the period. The
turnover is a total of voluntary and involuntary
terminations. The employee turnover ratio is
calculated by dividing the number of employees
who left ALK by the average number of employees
in the reporting year. The employees included in
the calculation are all permanent employees and
inactive employees on garden leave. Due to local
regulations, temporary employees located in
Poland and China are also included, as a tempo-
rary contract is required before transitioning to
permanent status.
Management's
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statement
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information
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chain
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end-users
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– Social information
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information
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statements
Annual Report 2025 70Social information
Consumers and end-users
Number of patients in treatment (significant
estimate)
Due to the absence of comprehensive data
sources across all markets, it is not possible to
directly and specifically measure the number
of patients treated with ALK products. Patient
numbers are estimated using various data
sources, an in-house Patient Model and in-house
model for BULKS, while applying several assump-
tions, which leads to a certain level of uncertainty.
The use of estimates for this datapoint is consid-
ered significant.
When a more precise method is not available,
units sold ex-factory are converted to treatment
years per patient using a treatment years conver-
sion factor. This estimation is adjusted based on
market and patient research from various coun-
tries, applying an adherence rate and a co-ad-
ministration rate across products and countries
to prevent e.g. double counting patients receiving
multiple types of allergy immunotherapy treat-
ments (AIT) simultaneously.
When available, more precise methods are
tailored to specific product groups as follows:
For SLIT-drops in most markets, anonymised data
and unique patients counted based on prescrip-
tion data are used.
For SLIT-tablets in most markets, data is based
on the in-house Patient Model. The Patient
Model uses in-market unit sales data and where
possible new patient data to convert to patients
in treatment. Actual in-market sales and patient
data are used for two-thirds of the year, while the
remaining portion is forecasted. A co-administra-
tion rate is applied to tablet patients.
In North America, ALK sells bulk allergen extracts
to healthcare professionals who prepare the
allergy shots using various and unspecified
dosing schedules. To estimate the number of bulk
AIT-treated patients, SAP BI in-house data is used.
Sold volumes by allergen into patient-equivalent
treatments is converted by applying the average
mL used per treatment. The “treatment doses”
divided by average number of allergens per treat-
ment serves as a proxy for the number of patients
in the selected period.
For the Auto Adrenaline Injector (AAI), following
official recommendations, the number of sold
pens is divided by 2 to reflect the assumption that
each patient carries two pens at a time.
Management's
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end-users
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information
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statements
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Governance information
Business conduct
G1
ALK is committed to responsible, ethical busi-
ness conduct, guided by the principles set out
in its Code of Conduct. ALK upholds high stand-
ards of integrity and prioritises animal welfare,
in line with applicable laws and regulations.
Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Breaches of legal and ethical standards
Non-compliance with applicable regulation and legis-
lation, or ALK’s Code of Conduct, could lead to severe
penalties, fines, legal battles, and damage to ALK’s
reputation.
Risk
Corporate culture
Policies
G1-1
ALK's approach to business conduct is
grounded in a comprehensive framework of
policies centred on its Code of Conduct. They
apply to all ALK employees and are publicly
accessible via ALK’s website.
Code of Conduct
The Code of Conduct, applicable to all ALK
employees, sets the tone for business integrity
and ALK’s ethical principles. It affirms ALK's
commitment to upholding human rights, safe-
guarding confidential business information,
and promoting zero-tolerance for corruption
and fraud.
Oversight of the Code of Conduct rests with
the Executive Leadership Team (ELT). ALK’s
Compliance Committee assists the ELT in
fulfilling its oversight responsibilities as well
as approval of compliance programmes in the
areas of business ethics conduct.
Information about corporate governance can be found
on page 29.
Management's
review
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statement
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informationinformation
Environmental Environmental
informationinformation
Social Social
informationinformation
Governance Governance
informationinformation
Business conduct Business conduct
Accounting policies Accounting policies
– Governance – Governance
informationinformation
AppendixAppendix
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statements
Annual Report 2025 72Governance information
Governance information
Training requirements on business conduct
are formalised in the newly established Global
Business Ethics Compliance Programme policy.
See Training and awareness on pages 73-74 for more
details.
Policy for Anti-Corruption
The policy for anti-corruption addresses
compliance with general anti-bribery and
anti-corruption legislation, as well as indus-
try-specific standards covering interactions
with healthcare professionals. It is consistent
with the United Nations Convention against
Corruption.
The Board of Directors is responsible for
ensuring that the policy complies with appli-
cable laws, while managers are responsible
for implementing the policy at all levels.
Whistleblowing policy
The Whistleblowing policy defines the organ-
isation and processes in place to ensure
that ethical concerns are treated seriously
and appropriately; it includes the standards
for investigating such cases and protecting
whistleblowers. The policy includes a non-re-
taliation commitment to protect any employee
or stakeholder who raises a concern in good
faith.
The Audit Committee has the overall respon-
sibility for the Whistleblowing policy, and for
reviewing the effectiveness of actions taken in
response to concerns raised under the policy.
The Legal & Compliance department has
day-to-day operational responsibility for the
policy.
Third-Party Code of Conduct
In parallel with the policies applicable to ALK’s
employees, expectations for business partners
are outlined in the Third-Party Code of Conduct,
which covers ALK’s upstream and downstream
value chain. ALK’s Whistleblowing policy also
applies to external stakeholders.
Details on the Third-Party Code of Conduct are
provided in Policies on page 65.
Training and awareness
G1-3,4
Training and awareness activities are vital for
promoting a culture of integrity and estab-
lishing a shared understanding of expecta-
tions for ALK’s employees. All new hires must
confirm their commitment to act in accordance
with the Code of Conduct. Employees are
exposed to risks of bribery and corruption,
particularly during interactions with health-
care professionals (HCPs). For ALK, the prin-
cipal risk relates to potential bribery of HCPs,
meaning improper influence to increase sales
and cash flow. To address this, ALK provides
annual online Code of Conduct training for all
Code of Conduct training completion
99%
Management's
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statements
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Unit 2025 2024
Training and awareness
Code of Conduct training completion
1
% 99% 98%
ALK Alertline
Work-related discrimination reports registered on
Alertline # 2 1
Reports of other work-related complaints # - 3
Amount of fines, penalties and compensation for
damages as a result of work-related complaints DKKm - -
Severe human rights incidents
Severe human rights incidents # - -
Amount of fines, penalties, and compensation for
damages for severe human rights incidents DKKm - -
Anti-corruption and bribery
Convictions for violation of anti-corruption
and bribery laws # - -
Fines for violation of anti-corruption
and bribery laws DKKm - -
1
In 2025, the metric has been revised to include all ALK employees The 2024 figure has been restated to reflect this updated
definition (previously 99%).
employees, including members of the Execu-
tive Leadership Team and employee represent-
atives on the Board of Directors.
The training covers relevant business conduct
topics including anti-corruption, ALK Alertline,
communications, promotion and social media,
competition law, conflicts of interest, political
contributions, human rights, interaction with
healthcare professionals, IT security, patient
safety, and data privacy.
ALK has set a global completion rate target of
95%. In 2025, 99% (2024: 98%) of employees
across all functions completed the training.
Whistleblowing and
anti-corruption system
G1-1,3
ALK has established a whistleblowing system,
ALK Alertline, which is accessible to internal
and external stakeholders via ALKs intranet
and public website. The company's own work-
force, workers in the value chain and other
external stakeholders with a work-related
connection to ALK can use the ALK Alertline
to raise and report serious and sensitive
concerns, including reasonable suspicions of
breaches of ALK’s Code of Conduct, anti-cor-
ruption laws, and laws within the scope of the
EU Whistleblower Protection Directive.
Available by phone or online in eight
languages, ALK Alertline is confidential and
offers the option of anonymous reporting, as a
protective measure against retaliation.
Reports are entered directly into an inde-
pendent company’s secure server. Legal &
Compliance manages the access, and the
reports are made available only to pre-ap-
pointed individuals within ALK who are respon-
sible for evaluating reports.
Allegations of breaches of legal and ethical
standards, including whistleblowing, corrup-
tion or bribery, are investigated under ALKs
Compliance Investigations process. Each
case is overseen by an investigation super-
visor, typically the Vice President, Legal &
Compliance or their designee. Where appro-
priate due to specific allegations in a report,
an external legal counsel or the Chair of the
Audit Committee may act as investigation
supervisor. The Chair of the Audit Committee is
notified of reports concerning corruption and
is responsible for approving recommendations
on such cases.
Legal & Compliance also provides the Audit
Committee with quarterly updates on ALK
Alertline activity.
ALK assesses awareness and trust in the
processes for raising concerns by including
questions in the annual engagement survey on
employees' confidence that ALK will address
serious misconduct and the importance
managers place on employee well-being.
In addition to ALK Alertline, employees are
encouraged to speak up and raise any
concerns through ordinary management
channels. Managers are offered training on
handling whistleblower reports and ensuring
reporter protection, including against retali-
ation. With regard to corruption and bribery,
financial control systems also act to prevent
and detect any incidents.
Metrics
G1-4, S1-17
In 2025, ALK was not liable for any fines, penal-
ties, or compensation for damages as a result
of work-related Alertline reports or severe
human rights incidents.
ALK had no convictions or related fines for
violations of anti-corruption and anti-bribery
laws.
Management's
review
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statement
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Impacts, risks and opportunities
SBM3
Location in
the value chain
Time
horizon
IRO
Upstream
Own
operations
Downstream
Short-term
Medium-term
Long-term
Animal welfare
ALK conducts animal testing to ensure its medicines
are safe and effective, using animals only when alter-
native models are insufficient. Experiments using
mouse allergy models, in which mice are administered
test substances like allergens or new treatments,
are conducted at internal R&D facilities or at external
partner’s facilities. Negative impacts on the animals
include handling, injections, captivity and euthanasia.
Actual
negative
impact
Animal welfare
Animal welfare policy
G1-1
In 2025, ALK introduced an animal welfare
policy, formalising its commitment to the
highest standards of animal welfare within
research and developmemt activities. Animal
studies are conducted only when no scientif-
ically valid alternative exists, and only when
justified by the potential benefits to patients
and society. ALK is committed to the principles
of Replace, Reduce, and Refine. All research
complies with relevant national and interna-
tional regulations, including the EU Directive
on protection of animals used for scientific
purposes, and Federation of European Labo-
ratory Animal Science Associations (FELASA)
guidelines, with equivalent standards upheld
globally.
The policy applies to all animal research
activities overseen by ALK, both within internal
facilities and in externally conducted in vivo
studies commissioned by ALK. It also covers
the collection and use of animal-derived mate-
rials for research when ALK is directly involved
in design, oversight, or contracting (e.g. sera,
tissues), but excludes routine collection of
animal by-products (e.g. hair).
Oversight of the animal welfare policy rests
with the ELT, which has formally approved the
policy. Day-to-day management is handled by
Global Research & Drug Discovery. Implemen-
tation of the policy is monitored through quar-
terly inspections by an external veterinarian,
as well as ongoing internal efforts to drive
continuous improvement.
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Business conduct
Accounting policies
– Governance
information
Appendix
Financial
statements
Annual Report 2025 75Governance information
Accounting policies – Governance information
The numeric datapoints reported are verified through
internal controls, analysis, benchmarks, and regular
business meetings. External auditors provide limited
assurance on 2024 and 2025 metrics, but they are
not validated by another external body.
Code of Conduct training
“Code of Conduct training completion” refers to the
percentage of ALK employees that completed the
Code of Conduct e-learning course. The Code of
Conduct e-learning course was rolled out between
May and July 2025.
Alertline
ALK Alertline is the company’s whistleblower system,
which can be used to report serious and sensitive
concerns – including serious offenses against
persons such as discrimination.
Work-related complaints and reports refer to alle-
gations registered on Alertline which involve ALK’s
own workforce. Severe human rights incidents refer
to substantiated incidents of human rights violations
pertaining to ALK’s own workforce.
Fines, penalties and compensation for damages are
“as a result” of allegations and complaints only when
such allegations and complaints are substantiated
and undisputed. They are reported in the reporting
year when they are imposed and final (i.e., the
amount is no longer under appeal or in dispute).
Incidents of corruption or bribery
Bribery can take the form of money, gifts, loans,
fees, hospitality, services, discounts, the award of
a contract or any other advantage or benefit, and
it comprises any financial or other inducement or
reward for an action which is illegal, unethical, a
breach of trust or improper in any way. Corruption is
defined as abuse of entrusted power by someone for
personal gain.
For purposes of the reporting, convictions in scope
are final decisions or acts by courts of law, which
constitute criminal convictions under applicable
local law in the jurisdiction where the decision or act
takes place. As required by the ESRS, only convictions
where ALK or its employees are directly involved
are considered within scope. Fines relating to such
convictions are reported in the reporting year when
they are imposed and final (i.e., no longer under
appeal or in dispute).
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Business conduct
Accounting policies
– Governance
information
Appendix
Financial
statements
Annual Report 2025 76Governance information
Appendix
Incorporation by reference
BP2
The table below provides an overview of all incorporations by reference as part of other sections of this annual report.
ESRS Disclosure requirement Incorporation by reference
Disclosed
on page
ESRS 2-BP2-16
See this table for the list of incorporation by reference and phased-in
datapoints.
77
ESRS 2-GOV1-21(a, b, d, e)
Composition, diversity and independence of Board of
Directors
See Corporate matters, section “Corporate governance and owner-
ship”, subsection table “Composition of the Board of Directors”.
30
ESRS 2-GOV1-23(a, b)
G1-GOV1-5(a, b)
Sustainability-related expertise and business conduct-re-
lated role of Board of Directors
See Corporate matters, section “Corporate governance and owner-
ship”, subsection “Competency matrix for the Board of Directors”,
first paragraph.
30
ESRS 2-GOV1-21c
Experience of Board of Directors' members relevant to
ALK's sectors, products and geographic locations
See Corporate matters, section “Board of Directors”, subheadings
“Competencies” and “Directorships”.
33-34
ESRS 2-GOV3
E1- GOV 3-13
Integration of sustainability-related performance in
incentive schemes
See Corporate matters, section “Corporate governance and owner-
ship”, subsection “Remuneration”, subheading “Highlights of the
remuneration report 2025.
30-31
ESRS 2-GOV4-32
Statement on due diligence See appendix “Core elements of due diligence. 78
ESRS 2-SBM1-40(a.i, a.ii, f)
Current significant products, significant markets and
customer groups
See Financial performance, section “Sales and market trends”,
tables “Revenue by geography” and “Revenue by product line”.
20
ESRS 2-SBM1-40e
Sustainability-related goals in terms of significant groups
of products, customer categories, geographical areas
and relationships with stakeholders
See Introduction, section “Sustainability highlights”, lead para-
graph.
10
ESRS 2-SBM1-42(a,b,c)
Business model and value chain See Introduction, section “Business model”, model “Business and
value chain”.
8
ESRS 2-IRO2-56
Content index of ESRS disclosure requirements; List of
datapoints that derive from other EU legislation
See appendices “Content index of ESRS disclosure requirements”
and “List of datapoints that derive from other EU legislation”.
78-82
E1-3-29c.i
CapEx and OpEx investment required to implement
actions taken or planned
Included in Financial statements, section “Consolidated finan-
cial statements”, Income statement; and subsection “Notes,
subheading “Section 3 – Operating assets and liability”, note 3.2.
87; 103
S1-6-50f
Most representative number corresponding to the total
number of employees
See in Financial statements, section “Consolidated financial state-
ments, subsection “Notes”, subheading “Section 2 – Results for the
year, note 2.4, Number year end (FTE).
96
EU Taxonomy turnover, CapEx and OpEx See appendix “EU Taxonomy” 83-84
Phased-in
Disclosure
Requirements
ESRS 2-SBM1-48b,c
Revenue by ESRS Sectors
ESRS 2-SBM3-48e
Anticipated financial effects
E1-9
Anticipated financial effects
from material physical and
transition risks and potential
climate-related opportu-
nities
E4
Biodiversity and Ecosystems
S1-7
Characteristics of non-em-
ployees in the undertaking’s
own workforce
S1-13-83b
Average training time per
employee and by gender
S1-14-88d
Cases of work-related illness
S1-14-88e
Lost time due to work-related
injuries, fatalities, and illness
Management's
review
Sustainability
statement
General General
informationinformation
Environmental Environmental
informationinformation
Social Social
informationinformation
Governance Governance
informationinformation
AppendixAppendix
Incorporation by Incorporation by
referencereference
Core elements of due Core elements of due
diligencediligence
Content index of Content index of
ESRS disclosure ESRS disclosure
requirementsrequirements
List of datapoints List of datapoints
that derive from that derive from
other EU legislationother EU legislation
EU Taxonomy EU Taxonomy
Financial
statements
Annual Report 2025 77Appendix
Appendix
Core elements of due diligence
GOV4
The table below maps the core elements of ALK's due diligence process, cross-referencing
the impacts on people and the environment with the relevant disclosures in the sustainability statement.
Core elements
of due diligence Sections in the sustainability statement Page
a) Embedding due diligence
in governance, strategy
and business model
Sustainability governance 39-40
Material impacts, risks and opportunities 43
Environmental information 44-58
Social information 59-71
Governance information 72-76
b) Engaging with affected
stakeholders in all key steps
of the due diligence
Sustainability governance 39-40
Stakeholder engagement 41
Materiality assessment process 42
Environmental information 44-58
Social information 59-71
c) Identifying and assessing
adverse impacts
Materiality assessment process 42
Material impacts, risks and opportunities 43
Environmental information 44-58
Social information 59-71
Governance information 72-76
d) Taking actions to
address those adverse
impacts
Environmental information 44-58
Social information 59-71
Governance information 72-76
e) Tracking effectiveness of
these efforts and commu-
nicating
Environmental information 44-58
Social information 59-71
Governance information 72-76
Content index of ESRS disclosure requirements
The table below presents the disclosure requirements from ESRS 2 and the nine topical standards
relevant to ALK and indicates where to find information related to each specific requirement.
Disclosure Requirements in ESRS covered by
the undertaking’s sustainability statement
IRO2
Disclosure
Requirement Description Page
ESRS 2
General Disclosures
BP-1
General basis for preparation of the sustainability statement 38
BP-2
Disclosures in relation to specific circumstances 38; 77
GOV-1
The role of the administrative, management and supervisory bodies 30; 33-34;
39
GOV-2
Information provided to and sustainability matters addressed by the under-
taking’s administrative, management and supervisory bodies
39; 43
GOV-3
Integration of sustainability-related performance in incentive schemes 30 -31; 39
GOV-4
Statement on due diligence 40; 78
GOV-5
Risk management and internal controls over sustainability reporting 40
SBM-1
Strategy, business model and value chain 8; 10; 20;
41; 64
SBM-2
Interests and views of stakeholders 41; 42
SBM-3
Material impacts, risks and opportunities and their interaction with strategy
and business model
43; 45;
50-51;
53-54;
60-61; 63;
65; 67; 72;
75
IRO-1
Description of the processes to identify and assess material impacts, risks
and opportunities
42
IRO-2
Disclosure Requirements in ESRS covered by the undertaking’s sustaina-
bility statement
43; 78-82
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 78Appendix
Disclosure
Requirement Description Page
E1
Climate change
GOV-3-E1
Integration of sustainability-related performance in incentive schemes 30-31; 39;
44-45
E1-1
Transition plan for climate change mitigation 44-46; 56
SBM-3-E1
Material impacts, risks and opportunities and their interaction with strategy
and business model
42; 45
IRO-1-E1
Description of the processes to identify and assess material climate-
related impacts, risks and opportunities
42
E1-2
Policies related to climate change mitigation and adaptation 45
E1-3
Actions and resources in relation to climate change policies 45-47; 87;
103
E1-4
Targets related to climate change mitigation and adaptation 46-49
E1-5
Energy consumption and mix 47-49
E1-6
Gross Scopes 1, 2, 3 and Total GHG emissions 47-49
E2
Pollution
IRO-1-E2
Description of the processes to identify and assess material pollution-
related impacts, risks and opportunities
42
E2-1
Policies related to pollution 50
E2-2
Actions and resources related to pollution 50
E2-3
Targets related to pollution 50
E2-5
Substances of concern and substances of very high concern 50
E3
Water and Marine Resources
IRO-1-E3
Description of the processes to identify and assess material water and
marine resources-related impacts, risks and opportunities
42
E3-1
Policies related to water and marine resources 51
E3-2
Actions and resources related to water and marine resources 51-52
E3-3
Targets related to water and marine resources 52
E3-4
Water consumption 52
Disclosure
Requirement Description Page
E4
Biodiversity and ecosystems
E4-1
Transition plan and consideration of biodiversity and ecosystems in
strategy and business model
Phase-in
SBM-3-E4
Material impacts, risks and opportunities and their interaction with strategy
and business model
Phase-in
IRO-1-E4
Description of processes to identify and assess material biodiversity and
ecosystem-related impacts, risks dependencies and opportunities
Phase-in
E4-2
Policies related to biodiversity and ecosystems Phase-in
E4-3
Actions and resources related to biodiversity and ecosystems Phase-in
E4-4
Targets related to biodiversity and ecosystems Phase-in
E5
Resource Use and Circular Economy
IRO-1-E5
Description of the processes to identify and assess material resource use
and circular economy-related impacts, risks and opportunities
42
E5-1
Policies related to resource use and circular economy 54
E5-2
Actions and resources related to resource use and circular economy 54
E5-3
Targets related to resource use and circular economy 54
E5-4
Resource inflows 55
E5-5
Resource outflows 55
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 79Appendix
Disclosure
Requirement Description Page
S1
Own workforce
SBM-2-S1
Interests and views of stakeholders 41
SBM-3-S1
Material impacts, risks and opportunities and their interaction with strategy
and business model
60; 61; 63
S1-1
Policies related to own workforce 59; 61; 63;
72-73
S1-2
Processes for engaging with own workforce and workers' representatives
about impacts
59
S1-3
Processes to remediate negative impacts and channels for own workforce
to raise concerns
59; 60; 63
S1-4
Taking action on material impacts on own workforce, and approaches to
mitigating material risks and pursuing material opportunities related to
own workforce, and effectiveness of those actions
60; 61; 63
S1-5
Targets related to managing material negative impacts, advancing positive
impacts, and managing material risks and opportunities
61
S1-6
Characteristics of the undertaking’s employees 64; 96
S1-9
Diversity metrics 62
S1-13
Training and skills development metrics 60
S1-14
Health and safety metrics 63
S1-16
Remuneration metrics (pay gap and total remuneration) 62
S1-17
Incidents, complaints and severe human rights impacts 63; 74
S2
Workers in the Value Chain
SBM-2-S2
Interests and views of stakeholders 41
SBM-3-S2
Material impacts, risks and opportunities and their interaction with strategy
and business model
65
S2-1
Policies related to value chain workers 65
S2-2
Processes for engaging with value chain workers about impacts 66
S2-3
Processes to remediate negative impacts and channels for value chain
workers to raise concerns
66
S2-4
Taking action on material impacts on value chain workers, and approaches
to managing material risks and pursuing material opportunities related to
value chain workers, and effectiveness of those actions
66; 74
S2-5
Targets related to managing material negative impacts, advancing positive
impacts, and managing material risks and opportunities
66
Disclosure
Requirement Description Page
S4
Consumers and End-users
SBM-2-S4
Interests and views of stakeholders 41
SBM-3-S4
Material impacts, risks and opportunities and their interaction with strategy
and business model
67
S4-1
Policies related to consumers and end-users 68
S4-2
Processes for engaging with consumers and end-users about impacts 68; 41
S4-3
Processes to remediate negative impacts and channels for consumers and
end-users to raise concerns
69; 74
S4-4
Taking action on material impacts on consumers and end-users, and
approaches to managing material risks and pursuing material opportunities
related to consumers and end-users, and effectiveness of those actions
69
S4-5
Targets related to managing material negative impacts, advancing positive
impacts, and managing material risks and opportunities
69
G1
Business Conduct
SBM-3-G1
Material impacts, risks and opportunities and their interaction with strategy
and business model
72; 75
GOV-1- G1
The role of the administrative, management and supervisory bodies 30
IRO-1-G1
Description of the processes to identify and assess material impacts, risks
and opportunities
42
G1-1
Business conduct policies and corporate culture 65; 72-74
G1-3
Prevention and detection of corruption and bribery 73-74
G1-4
Incidents of corruption or bribery 73-74
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 80Appendix
List of datapoints that derive from other EU legislation
IRO2
The table below includes all the ESRS datapoints that derive from other EU legislation and indicates where the
information can be found if deemed material.
Datapoints that derive from other EU legislation Page
ESRS 2
General disclosures
21 (d)
Board's gender diversity 30
21 (e)
Percentage of board members who are independent 30
30
Statement on due diligence 78
40 (d) i
Involvement in activities related to fossil fuel activities Not material
40 (d) ii
Involvement in activities related to chemical production Not material
40 (d) iii
Involvement in activities related to controversial weapons Not material
40 (d) iv
Involvement in activities related to cultivation and production of tobacco Not material
E1
Climate change
14
Transition plan to reach climate neutrality by 2050 44-45
16 (g)
Undertakings excluded from Paris-aligned Benchmarks 45
34
GHG emission reduction targets 46
38
Energy consumption from fossil sources disaggregated by sources (only high
climate impact sectors)
49
37
Energy consumption and mix 49
40-43
Energy intensity associated with activities in high climate impact sectors 49
44
Gross Scope 1, 2, 3 and Total GHG emissions 48
53-55
Gross GHG emissions intensity 48
56
GHG removals and carbon credits Not material
66
Exposure of the benchmark portfolio to climate-related physical risks Phase-in
66 (a)
Disaggregation of monetary amounts by acute and chronic physical risk Phase-in
66 (c)
Location of significant assets at material physical risk Phase-in
67 (c)
Breakdown of the carrying value of its real estate assets by energy-efficiency
classes
Phase-in
69
Degree of exposure of the portfolio to climate- related opportunities Phase-in
Datapoints that derive from other EU legislation Page
E2
Pollution
28
Amount of each pollutant listed in Annex II of the E-PRTR Regulation (European
Pollutant Release and Transfer Register) emitted to air, water and soil
Not material
E3
Water
9
Water and marine resources 51
13
Dedicated policy 51
14
Sustainable oceans and seas Not material
28 (c)
Total water recycled and reused 52
29
Total water consumption in m
3
per net revenue on own operations 52
E4
Biodiversity
16 (a) i
Activities negatively affecting biodiversity-sensitive areas Phase-in
16 (b)
Impacts related to land degradation, desertification or soil sealing Phase-in
16 (c)
Operations affecting threatened species Phase-in
24 (b)
Sustainable land / agriculture practices or policies Phase-in
24 (c)
Sustainable oceans / seas practices or policies Phase-in
24 (d)
Policies to address deforestation Phase-in
E5
Resource use and circular economy
37 (d)
Non-recycled waste 55
39
Hazardous waste and radioactive waste 55
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 81Appendix
Datapoints that derive from other EU legislation Page
S1
Own workforce
14 (f)
Risk of incidents of forced labour Not material
14 (g)
Risk of incidents of child labour Not material
20
Human rights policy commitments 59
21
Due diligence policies on issues addressed by the fundamental International
Labor Organisation Conventions 1 to 8
59
22
Processes and measures for preventing trafficking in human beings 59
23
Workplace accident prevention policy or management system 63
32 (c)
Grievance/complaints handling mechanisms 59; 74
88 (b) and (c)
Number of fatalities and number and rate of work- related accidents 63
88 (e)
Number of days lost to injuries, accidents, fatalities or illness Phase-in
97 (a)
Unadjusted gender pay gap 62
97 (b)
Excessive CEO pay ratio 62
103 (a)
Incidents of discrimination 63; 74
104 (a)
Non-respect of UNGPs on Business and Human Rights and OECD 63; 74
S2
Workers in the value chain
11 (b)
Significant risk of child labour or forced labour in the value chain 65
17
Human rights policy commitments 65
18
Policies related to value chain workers 65
19
Non-respect of UNGPs on Business and Human Rights principles and OECD
guidelines
65
19
Due diligence policies on issues addressed by the fundamental International
Labor Organisation Conventions 1 to 8
65
36
Human rights issues and incidents connected to its upstream and down-
stream value chain
66; 74
Datapoints that derive from other EU legislation Page
S3
Affected communities
16
Human rights policy commitments Not material
17
Non-respect of UNGPs on Business and Human Rights, ILO principles or and
OECD guidelines
Not material
36
Human rights issues and incidents Not material
S4
Consumers and end-users
16
Policies related to consumers and end-users 68
17
Non-respect of UNGPs on Business and Human Rights and OECD guidelines 68
35
Human rights issues and incidents Not material
G1
Business conduct
10 (b)
United Nations Convention against Corruption Not material
10 (d)
Protection of whistle-blowers Not material
24 (a)
Fines for violation of anti-corruption and anti-bribery laws 74
24 (b)
Standards of anti-corruption and anti- bribery 74
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 82Appendix
EU Taxonomy
Taxonomy turnover
Proportion of turnover from products or services associated with Taxonomy-eligible or Taxonomy-aligned economic activities - disclosure covering year 2025
Reported KPI Turnover
Financial year 2025 Environmental objective of Taxonomy aligned activities
Economic Activities
(1)
Code
(2)
Taxonomy eligible
KPI (Proportion of
Taxonomy eligible
Turnover)
(3)
Taxonomy aligned
KPI (monetary value
of Turnover / CapEx
/ OpEx)
(4)
Taxonomy aligned
KPI (Proportion of
Taxonomy aligned
Turnover. CapEx.
OpEx
(5)
Mitigation
Climate
Change
(6)
Adaptation
Climate
Change
(7)
Water
(8)
Circular
Economy
(9)
Pollution
(10)
Biodiversity
(11)
Enabling
activity
(12)
Transitional
activity
(13)
Proportion of
Taxonomy aligned
in Taxonomy
eligible
(14)
% DKKm %
% % % % % % %
Manufacture of active pharmaceutical ingredients
(API) or active substance PP C 1.1 0.3% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Manufacturing of Medicinal products PPC 1.2 97.1% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Sum of alignment per objective 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Total KPI (Turnover) 97.4% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Taxonomy CapEx
Proportion of CapEx from products or services associated with Taxonomy-eligible or Taxonomy-aligned economic activities - disclosure covering year 2025
Reported KPI CapEx
Financial year 2025 Environmental objective of Taxonomy aligned activities
Economic Activities
(1)
Code
(2)
Taxonomy eligible
KPI (Proportion of
Taxonomy eligible
CapEx)
(3)
Taxonomy aligned
KPI (monetary value
of Turnover / CapEx
/ OpEx)
(4)
Taxonomy aligned
KPI (Proportion of
Taxonomy aligned
Turnover, CapEx,
OpEx (5)
Mitigation
Climate
Change
(6)
Adaptation
Climate
Change
(7)
Water
(8)
Circular
Economy
(9)
Pollution
(10)
Biodiversity
(11)
Enabling
activity
(12)
Transitional
activity
(13)
Proportion of
Taxonomy aligned
in Taxonomy
eligible
(14)
% DKKm %
% % % % % % %
Manufacturing of Medicinal products PPC 1.2 41.0% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Installation, maintenance and repair of energy
efficiency equipment (CapEx C) CC M 7. 3 1.1% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% E 0.0%
Installation, maintenance and repair of instru-
ments and devices for measuring, regulation and
controlling energy performance of buildings CC M 7. 5 0.0% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% E 0.0%
Installation, maintenance and repair of renewable
energy technologies CC M 7.6 1.3% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% E 0.0%
Acquisition and ownership of buildings C C M 7.7 2 7.9% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Sum of alignment per objective 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Total KPI (CapEx) 71.4% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 83Appendix
Taxonomy OpEx
Proportion of OpEx from products or services associated with Taxonomy-eligible or Taxonomy-aligned economic activities - disclosure covering year 2025
Reported KPI OpEx
Financial year 2025 Environmental objective of Taxonomy aligned activities
Economic Activities
(1)
Code
(2)
Taxonomy eligible
KPI (Proportion of
Taxonomy eligible
CapEx)
(3)
Taxonomy aligned
KPI (monetary value
of Turnover / CapEx
/ OpEx)
(4)
Taxonomy aligned
KPI (Proportion of
Taxonomy aligned
Turnover, CapEx,
OpEx (5)
Mitigation
Climate
Change
(6)
Adaptation
Climate
Change
(7)
Water
(8)
Circular
Economy
(9)
Pollution
(10)
Biodiversity
(11)
Enabling
activity
(12)
Transitional
activity
(13)
Proportion of
Taxonomy aligned
in Taxonomy
eligible
(14)
% DKKm %
% % % % % % %
Manufacturing of Medicinal products PPC 1.2 45.1% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Transport by motorbikes, passenger cars and light
commercial vehicles (OpEx C) CCM 6.5 8.0% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% T 0.0%
Sum of alignment per objective 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Total KPI (OpEx) 53.1% 0 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Accounting policies
The turnover, OpEx and CapEx numerators are determined from ALK’s assessment of the relevant economic activities within all six environmental objectives.
The turnover denominator is derived from ALK‘s total group turnover of the consolidated financial statements (
note 2.1, p. 94).
The CapEx denominator is derived from the ALK group’s total annual investments in property, plant and equipment as well as intangible assets, excluding leases, as stated in consolidated financial statements (
notes 3.1 - 3.3, p. 101-106).
The OpEx denominator covers direct non-capitalised costs that primarily relate to repair and maintenance, costs of materials, car expenses, and any other direct expenditures relating to the servicing of group assets that are necessary to ensure
the continued and effective functioning of such assets.
Management's
review
Sustainability
statement
General
information
Environmental
information
Social
information
Governance
information
Appendix
Incorporation by
reference
Core elements of due
diligence
Content index of
ESRS disclosure
requirements
List of datapoints
that derive from
other EU legislation
EU Taxonomy
Financial
statements
Annual Report 2025 84Appendix
Financial
statements
The Financial Statements of ALK form an integral part of
the Annual Report and have been prepared in accordance
with International Financial Reporting Standards (IFRS) as
adopted by the EU. The accompanying Group and Parent
financial statements provide a true and fair view of ALK’s
financial position, performance, and cash flows for the year
ended 31 December 2025.
Management's
review
Sustainability
statement
Financial
statements
Consolidated Consolidated
financial financial
statementsstatements
Parent company Parent company
financial financial
statementsstatements
StatementsStatements
Other Other
informationinformation
Annual Report 2025 85
87 Income statement
87 Statement of comprehensive income
88 Cash flow statement
89 Balance sheet
90 Statement of changes in equity
91 Notes
125 Definitions
Section 1
Basis of reporting
1.1 Accounting policy information 91
1.2 Significant accounting estimates and judgements 93
Section 2
Results for the year
2.1 Revenue and segment information 94
2.2 Expenses 95
2.3 Depreciation, amortisation and impairment 96
2.4 Staff costs 96
2.5 Fees to the ALK Group’s auditors 97
2.6 Financial income and expenses 97
Section 3
Operating assets and liabilities
3.1 Intangible assets 101
3.2 Property, plant and equipment 103
3.3 Leases 105
3.4 Inventories 107
3.5 Trade receivables 108
3.6 Prepayments 108
3.7 Pensions and similar liabilities 109
3.8 Provisions 111
3.9 Other payables 111
3.10 Contingent liabilities and commitments 112
Section 4
Capital structure and financing
4.1 Share capital and earnings per share 113
4.2 Financial risks and financial instruments 114
Section 5
Other disclosures
5.1 Share-based payments 118
5.2 Cash flow 121
5.3 Business combinations 122
5.4 Related parties 123
5.5 Events after the reporting period 123
5.6 Approval of financial statements 123
5.7 List of companies in the ALK Group 124
NotesContents
Management's
review
Sustainability
statement
Financial
statements
Consolidated Consolidated
financial financial
statementsstatements
Income statementIncome statement
Statement of Statement of
comprehensive comprehensive
incomeincome
Cash flow statementCash flow statement
Balance sheetBalance sheet
Statement of changes Statement of changes
in equityin equity
NotesNotes
DefinitionsDefinitions
Parent company Parent company
financial financial
statementsstatements
StatementsStatements
Other Other
informationinformation
Annual Report 2025 86Consolidated financial statements
Consolidated financial statements
Income statement Statement of comprehensive income
Amounts in DKKm Note 2025 2024
Revenue
2.1 6,312 5,537
Cost of sales
2.2-2.4, 3.4, 5.1 2,078 1,985
Gross profit 4,234 3,552
Research and development expenses
2.2-2.4, 5.1 609 531
Sales and marketing expenses
2.2-2.4, 5.1 1,584 1,564
Administrative expenses
2.2-2.4, 5.1 388 369
Other operating income 1 3
Operating profit (EBIT) 1,654 1,091
Financial income
2.6 28 61
Financial expenses
2.6 47 95
Profit before tax (EBT) 1,635 1,057
Tax on profit
2.7 438 242
Net profit 1,197 815
Earnings per share (EPS)
4.1
Earnings per share (EPS) 5,40 3.68
Earnings per share (DEPS), diluted 5,40 3.68
Amounts in DKKm Note 2025 2024
Net profit 1,197 815
Items that will subsequently not be reclassified
to the income statement:
Actuarial gains/(losses) on pension plans 3.7 13 3
Tax related to actuarial gains/(losses) on pension plans
2.7 (4) (1)
9 2
Items that will subsequently be reclassified to
the income statement, when specific conditions are met:
Foreign currency translation adjustment of foreign affiliates (168) 83
(168) 83
Other comprehensive income (159) 85
Total comprehensive income 1,038 900
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Income statement
Statement of
comprehensive
income
Cash flow statement
Balance sheet
Statement of changes
in equity
Notes
Definitions
Parent company
financial
statements
Statements
Other
information
Annual Report 2025Consolidated financial statements 87
Cash flow statement
Amounts in DKKm Note 2025 2024
Net profit 1,197 815
Adjustments
Adjustments for non-cash items
5.2 830 640
Changes in working capital
5.2 (149) (151)
Financial income, received 71 17
Financial expenses, paid (51) (13)
Income tax, paid (net) (81) (95)
Cash flow from operating activities 1,817 1,213
Acquisitions of companies and operations
5.3 (10) (115)
Purchase of intangible assets
3.1 (84) (1,043)
Purchase of tangible assets
3.2-3.3 (276) (260)
Investments in other financial assets (15) 1
Cash flow from investing activities (385) (1,417)
Free cash flow 1,432 (204)
Sale of treasury shares - 6
Exercised share options, paid (26) (38)
Proceeds from borrowings
5.2 - 671
Repayment of borrowings
5.2 (688) (279)
Repayment of lease liabilities
5.2 (46) (50)
Cash flow from financing activities (760) 310
Net cash flow 672 106
Cash beginning of year 589 474
Unrealised gain/(loss) on cash held in foreign currency and
financial assets carried as cash (21) 9
Net cash flow 672 106
Cash year end 1,240 589
The consolidated statement of cash flow is compiled using the indirect method. As a result, the individual figures in the cash flow
statement cannot be reconciled directly to the income statement and the balance sheet.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Income statement
Statement of
comprehensive
income
Cash flow statement
Balance sheet
Statement of changes
in equity
Notes
Definitions
Parent company
financial
statements
Statements
Other
information
Annual Report 2025Consolidated financial statements 88
Balance sheet
Balance sheet – Assets Balance sheet – Equity and liabilities
Amounts in DKKm Note
31 Dec.
2025
31 Dec.
2024
Non-current assets
Intangible assets
Goodwill
3.1 455 463
Other intangible assets
3.1 1,310 1,329
1,765 1,792
Tangible assets
Land and buildings
3.2-3.3 1,005 1,137
Plant and machinery
3.2 663 603
Other fixtures and equipment
3.2-3.3 72 79
Property, plant and equipment in progress
3.2 524 528
2,264 2,347
Other non-current assets
Prepayments and securities 48 26
Deferred tax assets
2.7 353 642
Income tax receivables 133 145
534 813
Total non-current assets 4,563 4,952
Current assets
Inventories
3.4 1,783 1,716
Trade receivables
3.5 1,093 812
Receivables from group companies
5.4 118 -
Income tax receivables
8 10
Other receivables 120 49
Prepayments
3.6 132 118
Cash 1,240 589
Total current assets 4,494 3,294
Total assets 9,057 8,246
Amounts in DKKm Note
31 Dec.
2025
31 Dec.
2024
Equity
Share capital
4.1 111 111
Currency translation adjustment (103) 65
Retained earnings 6,082 5,197
Proposed dividends 355 -
Total equity 6,445 5,373
Liabilities
Non-current liabilities
Mortgage debt
4.2 151 166
Pensions and similar liabilities
3.7 244 251
Lease liabilities
4.2 204 285
Deferred income 277 45
Provisions
3.8 1 1
Deferred tax liabilities
2.7 238 3
Income tax payables 168 173
1,283 924
Current liabilities
Mortgage debt
4.2 17 19
Bank loans
4.2 - 671
Trade payables 140 165
Lease liabilities
4.2 46 46
Deferred income 11 4
Provisions
3.8 20 38
Income tax payables 39 124
Other payables
3.9 1,056 882
1,329 1,949
Total liabilities 2,612 2,873
Total equity and liabilities 9,057 8,246
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Income statement
Statement of
comprehensive
income
Cash flow statement
Balance sheet
Statement of changes
in equity
Notes
Definitions
Parent company
financial
statements
Statements
Other
information
Annual Report 2025Consolidated financial statements 89
Statement of changes in equity
Amounts in DKKm
Share
capital
Currency
translation
adjust-
ment
Retained
earnings
Proposed
dividend
Total
equity
2025
Equity at 1 January 111 65 5,197 - 5,373
Net profit - - 842 355 1,197
Other comprehensive
income/(loss) - (168) 9 - (159)
Total comprehensive income - (168) 851 355 1,038
Share-based payments - - 45 - 45
Share options settled - - (26) - (26)
Tax related to items recognised
directly in equity - - 15 - 15
Other transactions - - 34 - 34
Equity at 31 December 111 (103) 6,082 355 6,445
Amounts in DKKm
Share
capital
Currency
translation
adjust-
ment
Retained
earnings
Total
equity
2024
Equity at 1 January 111 (18) 4,354 4,447
Net profit - - 815 815
Other comprehensive income/(loss) - 83 2 85
Total comprehensive income - 83 817 900
Share-based payments - - 51 51
Share options settled - - (38) (38)
Sale of treasury shares - - 6 6
Tax related to items recognised directly in equity - - 8 8
Other adjustments - - (1) (1)
Other transactions - - 26 26
Equity at 31 December 111 65 5,197 5,373
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Income statement
Statement of
comprehensive
income
Cash flow statement
Balance sheet
Statement of changes
in equity
Notes
Definitions
Parent company
financial
statements
Statements
Other
information
Annual Report 2025Consolidated financial statements 90
Section 1 – Basis of reporting
Notes
The consolidated financial statements for the
period 1 January to 31 December 2025 have been
prepared in accordance with the IFRS accounting
standards as adopted by the EU and in accord-
ance with Danish disclosure requirements for
listed companies. Additional Danish disclosure
requirements for annual reports are imposed by
the Statutory Order on Adoption of IFRS issued
under the Danish Financial Statements Act.
The consolidated financial statements are
presented in Danish kroner (DKK), which is consid-
ered the primary currency of the ALK Group’s
activities and the functional currency of the
parent company.
The consolidated financial statements are
presented on a historical cost basis, apart from
certain financial instruments, which are measured
at fair value.
The general accounting policies described below
apply to the consolidated financial statements
as a whole. To enhance understanding, specific
accounting policies are described in the notes to
which they relate. The description of accounting
policies in the notes form part of the overall
description of accounting policies.
The accounting policies are unchanged from last
year.
New standards effective from
1 January 2025
The ALK Group has implemented all new and
amended standards and IFRIC interpretations
which are effective for the financial year 2025.
This have not resulted in any changes to the
accounting policies of the ALK Group.
New standards effective on or after
1 January 2026
A number of IFRS standards, amended standards
and IFRIC interpretations, which are effective on
or after 1 January 2026, have not been imple-
mented. Based on a preliminary assessment it is
estimated that these standards and interpreta-
tions will have no material impact on the consoli-
dated financial statements apart from IFRS18.
IFRS 18 Presentation and Disclosure in Finan-
cial Statements was issued by the International
Accounting Standards Board (IASB) in April 2024
and is not yet effective. The standard aims to
enhance the transparency and comparability of
financial performance by introducing new manda-
tory income statement presentation requirements
and enhanced disclosures for management-de-
fined performance measures (MPMs).
IFRS 18 will replace IAS 1 and will apply to annual
reporting periods beginning on or after 1 January
2027.
Key changes introduced by IFRS 18 include:
A revised structure of the income statement
with five defined categories: operating,
investing, financing, income taxes, and discon-
tinued operations
New mandatory subtotals, including operating
profit and profit before financing and income
tax
The ALK Group has provisionally assessed that
the impact of the standard and IFRS 18 will not
have any impact on profit or loss or equity at the
date of initial application.
The Group continues to assess the implications for
the presentation of the income statement and the
disclosure of management-defined performance
measures.
Basis of consolidation
The consolidated financial statements comprise
the financial statements of ALK-Abelló A/S (the
parent company) and companies (subsidiaries)
controlled by the parent company.
The consolidated financial statements are
prepared as a consolidation of items of a uniform
nature. The financial statements used for consol-
idation are prepared in accordance with the ALK
Groups accounting policies.
On consolidation, intra-group income and
expenses, intra-group balances and dividends,
and gains and losses arising on intra-group trans-
actions are eliminated.
Foreign currency translation
On initial recognition, transactions denominated
in currencies other than DKK are translated at
average exchange rates, which are an approxi-
mation of the exchange rates at the transaction
date. Receivables and debt and other monetary
items not settled at the balance sheet date are
translated at the closing rate.
Exchange rate differences between the exchange
rate at the date of the transaction and the
exchange rate at the date of payment or the
balance sheet date, respectively, are recognised
in the income statement under financial items.
Tangible assets and intangible assets, inventories
and other nonmonetary assets acquired in foreign
currency and measured based on historical cost
are translated at the exchange rates at the trans-
action date.
On recognition in the consolidated financial state-
ments of subsidiaries whose financial statements
are presented in a functional currency other
than DKK, the income statements are translated
at average exchange rates for the respective
months, unless these deviate materially from
the actual exchange rates at the transaction
1.1 Accounting policy information
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Income statement
Statement of
comprehensive
income
Cash flow statement
Balance sheet
Statement of changes
in equity
Notes
Definitions
Parent company
financial
statements
Statements
Other
information
Annual Report 2025Consolidated financial statements 91
Section 1 – Basis of reporting
1.1 Accounting policy information – continued
dates. In that case, the actual exchange rates
are used. Balance sheet items are translated at
the exchange rates at the balance sheet date.
Goodwill is considered to belong to the acquired
company in question and is translated at the
exchange rate at the balance sheet date.
Exchange rate differences arising on the trans-
lation of foreign subsidiaries’ opening balance
sheet items to the exchange rates at the balance
sheet date and on the translation of the income
statements from average exchange rates to
exchange rates at the balance sheet date are
recognised in other comprehensive income.
Foreign exchange rate adjustment of receivables
or debt to subsidiaries which are considered part
of the parent company’s overall investment in the
subsidiary in question are also recognised in other
comprehensive income in the consolidated finan-
cial statements.
Definitions and ratios
The key ratios have been calculated in accord-
ance with generally accepted financial ratios
applied by financial analysts. Definitions are
shown on page 125.
Reporting under the ESEF regulation
The Commission Delegated Regulation (EU)
2019/815 on the European Single Electronic
Format (ESEF) (ESEF Regulation) has introduced
a single electronic reporting format for the annual
financial reports of issuers with securities listed
on the EU regulated markets.
The ESEF Regulation sets out the following main
requirements: (1) Issuers shall draw up and
disclose their annual financial reports using the
XHTML format; and (2) issuers that draw-up their
primary consolidated financial statements in
accordance with IFRS as endorsed by the EU shall
tag those consolidated financial statements using
inline eXtensible Business Reporting Language
(iXBRL) including block-tag of the notes to the
consolidated financial statements.
The combination of the XHTML format with the
iXBRL tags makes the annual financial reports
both human-readable and machine-readable,
thus enhancing accessibility, analysis and
comparability of the information included in the
annual financial reports.
iXBRL tags shall comply with the ESEF taxonomy,
which is included in the ESEF Regulation and
developed based on the IFRS taxonomy published
by the IFRS Foundation.
As part of the tagging process financial state-
ment line items are marked up to elements in the
ESEF taxonomy. If a financial statement line item
is not defined in the ESEF taxonomy, an extension
to the taxonomy is created. Extensions have to
be anchored to elements in the ESEF taxonomy,
except for elements corresponding to subtotals.
The annual report 2025 for the ALK Group
submitted to the Danish Financial Supervisory
Authority and Nasdaq consists of the XHTML docu-
ment together with some technical files all included
in a ZIP file named alk-2025-12-31-en.zip.
Key definitions
XHTML (eXtensible HyperText Markup Language)
is a text-based markup language used to struc-
ture and mark up content such as text, images,
and hyperlinks in documents that are displayed
as Web pages in an updated standard Web
browser like Chrome or Edge.
iXBRL tags (or Inline XBRL tags) are hidden
meta-information embedded in the source code
of an XHTML document in accordance with the
Inline XBRL 1.1 specification, which enables the
conversion of XHTML-formatted information into
a machine-readable XBRL data record by appro-
priate software.
The tagging process is a process where iXBRL
tags are applied to financial statement line items,
notes, etc.
Taxonomy is an electronic dictionary of business
reporting elements used to report business data.
A taxonomy element is an element defined in a
taxonomy that is used for the machine-readable
labeling of information in an XBRL data record.
ESEF data
Name of reporting entity or other means of iden-
tification
ALK-Abelló A/S
Domicile of entity
Denmark
Legal form of entity
A/S
Country of incorporation
Denmark
Address of entity’s registered office
ge Allé 6-8, DK-2970 Hørsholm
Principal place of business
Global
Description of nature of entity’s
operations and principal activities
ALK is a global allergy solutions company
Name of parent entity
Lundbeckfond Invest A/S
Name of ultimate parent of group
Lundbeck Foundation
Management's
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Sustainability
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Financial
statements
Consolidated
financial
statements
Income statement
Statement of
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income
Cash flow statement
Balance sheet
Statement of changes
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Notes
Definitions
Parent company
financial
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Statements
Other
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Annual Report 2025Consolidated financial statements 92
Section 1 – Basis of reporting
1.2 Significant accounting estimates and judgements
In the preparation of the consolidated financial
statements according to IFRS, Management
is required to make certain estimates as many
financial statement items cannot be reliably
measured, but must be estimated. Such esti-
mates comprise judgements made on the basis
of the most recent information available at the
reporting date.
It may be necessary to change previous estimates
as a result of changes to the assumptions on
which the estimates were based or due to supple-
mentary information, additional experience or
subsequent events. Similarly, the value of assets
and liabilities often depends on future events that
are somewhat uncertain. In that connection, it is
necessary to set out e.g. a course of events that
reflects Management’s assessment of the most
probable outcome.
Management considers those listed below as
the key accounting estimates and related judge-
ments used in the preparation of the consolidated
financial statements.
A description of significant accounting estimates
and judgements as well as assumptions applied is
included in the relevant notes.
Estimate/ Note Key accounting estimates and judgementsjudgementPartnership agreements & sales deductions comprising rebates, discounts, and Estimate/ 2.1 Revenue and segment informationmandated price adjustmentsjudgementEstimate/ 2.7 Income tax and deferred tax Provision for uncertain tax positions and measurement of deferred tax assetsjudgementEstimate/ 3.1 Intangible assets Recoverable amount of goodwill and acquired intangible rightsjudgement3.4 Inventories Valuation of inventories and capitalisation of indirect production costs Estimate
Management's
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Financial
statements
Consolidated
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Income statement
Statement of
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Cash flow statement
Balance sheet
Statement of changes
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Notes
Definitions
Parent company
financial
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Statements
Other
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Annual Report 2025Consolidated financial statements 93
71%
13%
16%
34%
13%
53%
Section 2 – Results for the year
§ Accounting policies
Segment information
Based on the internal reporting used by the Board of Management to assess the results of operations and allocation
of resources, the ALK Group has identified one operating segment ‘Allergy treatment, which is in accordance with the
way the activities are organised and managed. Even though revenue within the operating segment “Allergy treatment
can be divided by product lines and market, the main part of the activities within production, research and develop-
ment, sales and marketing and administration are shared by the ALK Group as a whole. The disclosures in the financial
statements include a breakdown of revenue by product line and a geographical breakdown of revenue and non-current
assets. The geographical information on markets is based on customer and asset location.
Revenue
The primary performance obligation of the ALK Group is the sale and delivery of own-manufactured goods and goods for
resale for allergy treatment. Revenue from the sale of goods is recognised in the income statement upon the control of
the goods being transferred to the customer, i.e. when goods are delivered. Revenue is recognised by the ALK Group at a
point in time.
The ALK Group’s products are sold primarily to distributors of pharmaceuticals, pharmacies, and hospitals. The payment
conditions for the customers vary, and are based on industry practice in the relevant markets. As a result of special trading
conditions in specific markets, the credit period may be up to 180 days.
Revenue is measured as the fair value of the consideration received or receivable.
Revenue is measured exclusive of VAT, taxes, etc. charged on behalf of third parties and less any commissions and
discounts in connection with sales.
2.1 Revenue and segment information
International Europe North Americamarkets TotalAmounts in DKKm 2025 2024 2025 2024 2025 2024 2025 2024SLIT-tablets 2,485 2,080 247 209 603 562 3,335 2,851SCIT/SLIT-drops 1,619 1,568 356 361 170 123 2,145 2,052Anaphylaxis & other products 355 266 434 336 43 32 832 634Total revenue 4,459 3,914 1,037 906 816 717 6,312 5,537Sale of goods 6,169 5,426Royalties 96 108Services 47 3Total revenue 6,312 5,537
Of total revenue, DKK 136 million (2024: DKK 141 million) is derived from Denmark. The ALK Group had
more than 10% of its total revenue from Germany 25% (2024: 25%), France 16% (2024: 17%), and the USA
14% (2024: 14%) based on the location of the customers.
The ALK Group’s non-current tangible and intangible assets are distributed among the following
geographical markets:
International Europe North Americamarkets TotalAmounts in DKKm 2025 2024 2025 2024 2025 2024 2025 2024Non-current tangible and intangible assets 3,10 6 3,066 922 1,069 1 4 4,029 4,139
Of total non-current tangible and intangible assets, DKK 2,616 million relates to assets in Denmark
(2024: DKK 2,583 million). The USA accounts for 23% (2024: 26%) of total non-current tangible and intan-
gible assets.
Revenue by product line 2025
SLIT-tablets
SCIT/SLIT-drops
Anaphylaxis & other products
Revenue by geography 2025
Europe
North America
International
markets
Management's
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Financial
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Statement of
comprehensive
income
Cash flow statement
Balance sheet
Statement of changes
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Notes
Definitions
Parent company
financial
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Statements
Other
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Annual Report 2025Consolidated financial statements 94
Section 2 – Results for the year
2.1 Revenue and segment informationcontinued
Furthermore, revenue includes licence income and royalties from outlicensed products as well as up-front payments,
milestone payments and services in connection with partnerships. These revenues are recognised in the income state-
ment in accordance with the agreements and when the ALK Group obtains the right to the payments, which is when
services have been delivered to the customer or at the point in time the subsequent sales occur.
When combined contracts are entered, the elements of the contracts are identified and assessed separately for
accounting purposes.
Significant accounting estimates and judgements
Revenue recognition involves significant judgement due to the inherent complexity of the ALK Group’s revenue arrange-
ments, which arise from multiple sales channels and partnership agreements. These arrangements may include
differing contractual terms relating to pricing, performance obligations, revenue-sharing mechanisms, and the timing of
consideration.
Management exercises judgement in assessing the appropriate recognition of revenue under IFRS 15, including the
identification of performance obligations, the determination of whether the Group acts as principal or agent in certain
partnership arrangements, the estimation of variable consideration, and the assessment of the timing of satisfaction of
performance obligations.
The risk in revenue recognition relates primarily to the complexity of partnership agreements and sales channels, which
may impact the measurement and timing of revenue recognised. Management reviews contractual terms and applies
consistent accounting policies to ensure revenue is recognised in a manner that reflects the transfer of control of goods
or services to customers.
Sales deductions comprising rebates, discounts, and mandated price adjustments are estimated and accrued for at the
time when the related sales are recorded. Management is required to make significant estimates in the revenue recog-
nition relating to the accruals for sales deductions as not all conditions are known at the time of sale and as revenue can
only be recognised to the extent that it is probable that a significant reversal of the recognised revenue will not occur.
Management’s estimate of accruals for sales deductions is based on a calculation taking into consideration among
other factors, existing contractual obligations, the extent of predictability, historical experience with similar transac-
tions and whether the consideration is highly susceptible to factors outside ALKs influence.
ALK considers the accruals established for sales deductions to be reasonable and appropriate based on currently avail-
able information. The accruals for sales deductions are adjusted regularly as new or more detailed information becomes
available and when actual amounts are processed.
At 31 December 2025, DKK 314 million is recognised as accrued rebates, discounts, and mandated price adjustments
(2024: DKK 208 million), cf. note 3.9.
2.2 Expenses
§ Accounting policies
Cost of sales
The item comprises cost of sales and production costs incurred in generating the revenue for the year. Costs for raw
materials, consumables, goods for resale, production staff and a proportion of production overheads, including main-
tenance and depreciation, amortisation and impairment of tangible assets and intangible assets used in production as
well as operation, administration and management of factories, are recognised in cost of sales and production costs. In
addition, the costs and write-down to net realisable value of obsolete and slow-moving goods are recognised.
Research and development expenses
The item comprises research and development expenses, including expenses incurred for wages and salaries, amor-
tisation, impairment of capitalised development projects in progress, and other overheads as well as costs relating
to research partnerships. Research expenses are recognised in the income statement when incurred. Due to the long
development periods and significant uncertainties in relation to the development of new products, including risks
regarding clinical trials and regulatory approvals, it is the assessment that most of the ALK Group’s development
expenses do not meet the capitalisation criteria in IAS 38, Intangible Assets. Consequently, development expenses are
generally recognised in the income statement when incurred. Development expenses relating to individual minor devel-
opment projects running for short-term periods and subject to limited risk are capitalised under other intangible assets.
Clinical trials, which are outsourced to Clinical Research Organisations (“CROs”), take several years to complete. At 31
December 2025, DKK 50 million is recognised as accrued expenses (2024: DKK 24 million) and DKK 42 million as prepay-
ments in the balance sheet (2024: DKK 20 million). In 2025, external expenses for clinical trials of DKK 113 million have
been recognised in the income statement (2024: DKK 56 million).
Sales and marketing expenses
The item comprises selling and marketing expenses, including salaries and expenses relating to sales staff, advertising
and exhibitions, depreciation, amortisation and impairment losses on tangible assets and intangible assets used in the
sales and marketing process as well as other indirect costs.
Administrative expenses
The item comprises expenses incurred for management and administration, including expenses for administrative staff
and management, office expenses and depreciation, amortisation and impairment losses on tangible assets and intan-
gible assets used in administration.
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Annual Report 2025Consolidated financial statements 95
Section 2 – Results for the year
2.3 Depreciation, amortisation and impairment
Amounts in DKKm 2025 2024Depreciation, amortisation and impairment allocation:Cost of sales 242 185Research and development expenses 13 11Sales and marketing expenses 17 19Administrative expenses 56 57Total 328 272
Impairment amounts to DKK 10 million (2024: DKK 6 million), of which DKK 10 million relates to impairment
of tangible assets (2024: DKK 4 million). No impairment of intangible assets was made in the year (2024:
DKK 2 million).
The impairment of tangible assets is related to impairment of production equipment of DKK 10 million
(2024: DKK 3 million). The recoverable amount was DKK 0 million after impairment. The expense is recog-
nised as cost of sales. There were no impairments on administrative equipment during the year (2024:
DKK 1 million). The impairment prior year was recognised as cost of sales and administrative expenses.
2.4 Staff costs
Amounts in DKKm 2025 2024Wages and salaries 1,874 1,846Pensions, cf. note 3.7 145 151Other social security costs, etc. 250 250Share-based payments, cf. note 5.1 45 48Total 2,314 2,295
Staff costs are allocated as follows:Cost of sales 891 885Research and development expenses 350 331Sales and marketing expenses 767 786Administrative expenses 242 233Included in the cost of assets 64 60Total 2,314 2,295
Remuneration to Management:
Remuneration to Board of Management:
Salaries and other benefits 18 18Short-term incentive (cash bonus) 15 13Pensions 3 3Termination benefits 7 -Long-term incentives (share-based) based on expensed accounting value, 1cf. note 5.118 13Total remuneration to Board of Management 61 47Remuneration to Board of Directors 7 6Total remuneration to Board of Management and Board of Directors 68 53
Employees
Average number (FTE) 2,737 2,789
Number year end (FTE) 2,721 2,753
1
The expensed costs include DKK 6 million (2024: DKK 2 million) related to adjustment in the share options and performance
share units expected to vest.
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Annual Report 2025Consolidated financial statements 96
Section 2 – Results for the year
2.5 Fees to the ALK Group’s auditors
Amounts in DKKm 2025 2024Fees to the auditors appointed at the annual general meeting:Audit services 4 4Other opinions 2 2Tax advisory services 1 1Other services - -Total 7 7
The fee for non-audit services provided by PricewaterhouseCoopers Statsautoriseret Revisionspartner-
selskab (Denmark) of DKK 3 million (2024: DKK 3 million) relates to limited assurance of sustainability
statement, tax advisory, and other general financial accounting matters.
2.6 Financial income and expenses
Amounts in DKKm 2025 2024Interest income 28 61Financial income from financial assets measured at amortised cost 28 61Total financial income 28 61
1Interest expenses23 62Financial expenses from financial liabilities measured at amortised cost 23 62Interest expenses on uncertain tax positions, net 8 3Currency losses, net 16 30Total financial expenses 47 95
1
Interest expenses include interest related to leasing of DKK 9 million (2024: DKK 9 million).
§ Accounting policies
Financial items comprise interest receivable and interest payable, bank fees, the interest element of lease payments,
realised and unrealised gains and losses on securities, cash, liabilities and foreign currency transactions, mortgage
amortisation premium/allowance, etc. and provisions for uncertain tax position.
Interest expenses and income related to uncertain tax position are recognised on the balance sheet as tax liabilities and
tax assets respectively upon the receipt of ruling from the tax authorities and correspondingly reflected in the income
statement as financial items net.
Interest income and expenses are accrued based on the principal and the effective rate of interest. The effective rate of
interest is the discount rate to be used on discounting expected future payments in relation to the financial asset or the
financial liability so that their present value corresponds to the carrying amount of the asset or liability, respectively.
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Annual Report 2025Consolidated financial statements 97
Section 2 – Results for the year
2.7 Income tax and deferred tax
Amounts in DKKm 2025 2024Tax on profitCurrent income tax 203 215Adjustment of deferred tax 249 25Prior years adjustments (14) 2Tax on profit for the year 438 242Profit before tax 1,635 1,057Income tax, tax rate of 22% (2024: 22%) 360 233Effect of deviation of foreign subsidiaries’ tax rate relative to Danish tax rate 78 (10)Permanent differences (9) 3Other taxes and adjustments 23 14Prior years adjustments (14) 2Tax on profit for the year 438 242
Tax related to equity comprises an income of DKK 15 million (2024: income of DKK 8 million) and other
comprehensive income comprises an expense of DKK 4 million (2024: expense of DKK 1 million).
Pillar Two
The ALK Group falls within the scope of the OECD Pillar Two model rules and is part of the Danish joint
taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S). As the Lundbeck Foundation
Group has a revenue above EUR 750 million, the ALK Group is eligible for Pillar Two. The ALK group applies
the IAS 12 exception when recognising and disclosing information on deferred tax assets and liabilities
related to Pillar Two income taxes. Under this legislation, the ALK Group is required to pay a top-up tax for
any shortfall between its Global Anti-base Erosion (GloBE) effective tax rate in each jurisdiction and the
15% minimum rate.
ALK has applied Safe Harbour provisions and successfully met the Substance Test criteria. These results
confirm that ALK’s effective tax rate complies with the minimum requirements without further adjust-
ments. Certain estimates are subject to change with additional OECD guidance.
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Section 2 – Results for the year
2.7 Income tax and deferred tax – continued
Intangible Tangible Current and Tax losses Amounts in DKKmassetsassetsother assets Liabilitiescarried forward Total 2025Deferred taxCarrying amount beginning of year (248) (148) 557 157 321 639Adjustment to prior years’ deferred tax - - - - 2 2Adjustment of receivables from group companies - - - - (288) (288)Currency adjustments 1 5 (1) (3) (2) -Recognised in the income statement, net 11 10 (290) 32 (12) (249)Recognised in other comprehensive income, net - - - (4) - (4)Recognised in equity, net (share-based payments) - - 12 - 3 15Carrying amount year end (236) (133) 278 182 24 1152024Deferred taxCarrying amount beginning of year (27) (120) 279 124 399 655Adjustment to prior years’ deferred tax - (7) 2 7 (2) -Adjustment of receivables from group companies - - - - 2 2Currency adjustments - (2) - 2 - -Adjustment of deferred tax due to coming year change of tax rates - 1 (1) 1 - 1Recognised in the income statement, net (221) (20) 274 24 (83) (26)Recognised in other comprehensive income, net - - - (1) - (1)Recognised in equity, net (share-based payments) - - 3 - 5 8Carrying amount year end (248) (148) 557 157 321 639Deferred tax consists of deferred tax assets of DKK 353 million (2024: DKK 642 million) and deferred tax liabilities of DKK 238 million (2024: DKK 3 million). The ALK Group recognises deferred tax assets including the
value of tax losses if it is probable that it can be utilised against future taxable income within a forseeable future.
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Section 2 – Results for the year
2.7 Income tax and deferred tax – continued
§ Accounting policies
Tax on the profit for the year comprises the year’s current tax and changes in deferred tax. The tax expense relating to the
profit/loss for the year is recognised in the income statement, and the tax expense relating to items recognised in other
comprehensive income and directly in equity, respectively, is recognised in other comprehensive income or directly in
equity. Exchange rate adjustments of deferred tax are recognised as part of the adjustment of deferred tax for the year.
Current tax payable and receivable is recognised in the balance sheet as the expected tax on the taxable income for the
year, adjusted for tax paid on account.
The current tax charge for the year is calculated based on the tax rates and rules enacted at the balance sheet date.
Uncertain tax position is recognised for those matters for which the tax determination is uncertain but it is considered
probable that there will be a future outflow of funds to a tax authority (and a future inflow of funds from a tax authority). The
uncertain tax position is measured at the best estimate of the amount expected to become payable (and receivable).
Deferred tax is measured using the balance sheet liability method on all temporary differences between the carrying
amount and the tax base of assets and liabilities. However, deferred tax is not recognised on temporary differences
relating to the initial recognition of goodwill or the initial recognition of a transaction, apart from business combinations,
and where the temporary difference existing at the date of initial recognition affects neither profit/loss for the year nor
taxable income.
Deferred tax is calculated based on the planned use of each asset and settlement of each liability, respectively. Deferred
tax is measured using the tax rates and tax rules that, based on legislation enacted or in reality enacted at the balance
sheet date, are expected to apply in the respective countries when the deferred tax is expected to crystallise as current
tax. Changes in deferred tax as a result of changed tax rates or rules are recognised in the income statement, in other
comprehensive income or in equity, depending on where the deferred tax was originally recognised. Deferred tax related
to equity transactions is recognised in equity.
Deferred tax assets, including the tax value of tax loss carry-forwards, are recognised in the balance sheet at the value
at which the asset is expected to be realised, either through a set-off against deferred tax liabilities or as net assets to be
offset against future positive taxable income. Deferred tax assets including the tax value of tax losses are recognised if it
is probable that it can be utilised against future taxable income within a foreseeable future. This includes an assessment
of the possibilities to utilise tax losses in the joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond
Invest A /S).
At each balance sheet date, it is reassessed whether it is likely that there will be sufficient future taxable income for the
deferred tax asset to be utilised.
The parent company is included in a joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest
A/S) and its Danish subsidiaries. The tax charge for the year is allocated among the jointly taxed companies in propor-
tion to the taxable incomes of individual companies, taking into account taxes paid.
Significant accounting estimates and judgements
Management is required to make an estimate in the recognition of deferred tax assets. This assessment includes esti-
mates of future taxable income in ALK and other members of the joint Danish taxation scheme with the Lundbeck Founda-
tion.
At 31 December 2025, the deferred tax asset related to tax losses has been fully absorbed by other members of the joint
Danish taxation Scheme with the Lundbeck Foundation.
Complying with tax rules, when conducting business globally, can be complex as the interpretation of legislation and
case law may change over time or may not always be clear. Management’s judgements are applied to assess the
possible effect of exposures and the possible outcome of disputes or interpretational uncertainties when transfer
pricing disputes with local tax authorities may occur. Dialogue with local tax authorities, tax advisors, business plans
and knowledge of the business are key parameters for Management to estimate the tax assets and liabilities.
At 31 December 2025, the ALK Group recognises uncertain tax position as part of non-current tax. The actual outcome
may deviate and depends on the result of litigation and settlements with the relevant local tax authorities.
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Annual Report 2025Consolidated financial statements 100
Section 3 – Operating assets and liabilities
3.1 Intangible assets
Patents, Other trademarks intangible 1Amounts in DKKm Goodwill Softwareand rightsassetsTotal 2025Cost beginning of year 485 500 300 1,314 2,599Currency adjustments (7) (1) (24) (1) (33)Additions - 10 32 42 84Acquisition of companies and operations, cf. note 5.3 - - - - -Disposals - (4) - - (4)Transfer to/from other groups - 34 994 (1,028) -Cost year end 478 539 1,302 327 2,646Amortisation and impairment beginning of year 22 400 187 198 807Currency adjustments 1 (1) (12) 1 (11)Amortisation for the year - 34 51 4 89Disposals during the year - (4) - - (4)Impairment during the year, cf note 2.3 - - - - -Amortisation and impairment year end 23 429 226 203 881Carrying amount year end 455 110 1,076 124 1,7651 Other intangible assets include intangible assets in progress, and individual development projects running for short-term periods. In 2025, Patent licence of DKK 994 million, capitalised in 2024, was taken into use.
Patents, Other trademarks intangible 1Amounts in DKKm Goodwill Softwareand rightsassetsTotal 2024Cost beginning of year 481 479 204 304 1,468Currency adjustments 4 1 11 - 16Additions - 8 - 1,035 1,043Acquisition of companies and operations, cf. note 5.3 - - 118 - 118Disposals - (13) (33) - (46)Transfer to/from other groups - 25 - (25) -Cost year end 485 500 300 1,314 2,599Amortisation and impairment beginning of year 22 378 203 194 797Currency adjustments - 1 5 - 6Amortisation for the year - 32 12 4 48Disposals during the year - (13) (33) - (46)Impairment during the year, cf note 2.3 - 2 - - 2Amortisation and impairment year end 22 400 187 198 807Carrying amount year end 463 100 113 1,116 1,7921 Other intangible assets include intangible assets in progress, and individual development projects running for short-term periods. In 2024, ALK entered a Collaboration, License and Distribution Agreement with ARS Pharmaceuticals Operations Inc. where the asset of DKK 994 million was not ready for use due to pending regulatory and other approvals.
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Section 3 – Operating assets and liabilities
26%
2025
6% 61% 7%
3.1 Intangible assets – continued
Goodwill
Goodwill is related to acquisition of companies in previous years and has been subject to an impairment
test, which has been submitted to the Audit Committee for subsequent approval by the Board of Direc-
tors. The impairment test performed in 2025 revealed no need for impairment of goodwill.
Goodwill has been tested at an aggregated level for ALK as one cash-generating unit. In the calculation
of the value in use of the cash-generating unit, future free net cash flow is estimated based on Board
of Directors-approved budget (2026) and financial forecasts (2027-2029) in line with the ALK Group’s
strategy.
The budget and the forecast plans are based on specific future business initiatives for which the risks
relating to key parameters have been assessed and recognised in estimated future free cash flows.
The key parameters in the calculation of the value in use are revenue, earnings, working capital, capital-
expenditure, discount rate and the preconditions for the terminal value. Estimates are based on historical
data and expectations on future changes in the markets and products. These expectations are based on
a number of assumptions including expected regulatory approvals, product launches and partnership
agreements, volume forecasts, price information, development in clinical trials and pipelines and profit-
ability of both the ALK Group’s business as well as geographical expansions.
For financial years after the four year forecast period (2026-2029), the cash flows in the most recent
period have been extrapolated adjusted for a growth factor of 1.5% (2024: 1.5%) during the terminal
period. The discount rate used is 10.3% pre-tax and 8.0% after tax (2024: 10.3% pre-tax and 8.0% after
ta x).
The calculated value in use shows that future earnings and cash flows fully support the carrying amount
of total net assets, including goodwill.
§ Accounting policies
Goodwill
On initial recognition, goodwill is measured and recognised as the excess of the cost of the acquired company over the
fair value of the acquired assets, liabilities and contingent liabilities.
On recognition of goodwill, the goodwill amount is allocated to the ALK Group’s cash-generating unit. The ALK Group is
considered as one cash-generating unit as the individual companies and business units in the ALK Group cannot be eval-
uated separately due to the value-adding processes are generated across corporations and entities.
Goodwill is not amortised, but is tested for impairment at least once a year. To the extent that the carrying amount of good-
will exceeds the recoverable amount, goodwill is written down to this lower amount. Impairment of goodwill is not reversed.
Software, patents, trademarks and rights
Acquired intellectual property rights in the form of software, patents, trademarks, licenses, customer base, and similar
rights are measured at cost less accumulated amortisation and impairment.
The cost of software includes costs of installation and direct salaries.
Intangible assets with determinable useful lives are amortised on a straight-line basis over the expected useful lives of
the assets, typically not exceeding 15 years. If the actual useful life is shorter than either the remaining life or the contract
period, the asset is amortised over this shorter useful life. The carrying amounts are reviewed at the balance sheet date
to determine whether there are any indications of impairment. If such indications are identified, the recoverable amount
of the asset is calculated to determine any need for an impairment write-down and, if so, the amount of the write-down.
Intangible assets with indeterminable useful lives are not amortised, but are tested for impairment at least once a year.
To the extent that the carrying amount of the assets exceeds the recoverable amount, the assets are written down to this
lower amount.
See note 3.2 for more information on assessment, recognition and reversal of impairment.
Other intangible assets
Other intangible assets include individual minor development projects running for short-term periods, including software
development projects, which fulfil the requirements in IFRS. The measurement and impairment follow the same rules as
described above for software, patents, trademarks, and rights.
Significant accounting estimates and judgements
The assessment of whether goodwill and/or acquired intangible rights are impaired requires ALK management to make
judgments about the recoverable amount of each cash-generating unit or asset.
This involves estimating future economic benefits, including expected developments in revenues, gross profits, conver-
sion ratios, as well as the discount rates and long-term growth expectations applied in the terminal period.
These estimates are based on historical performance, current business plans, and expectations of future market condi-
tions, including long-term average market growth rates.
Management uses both internal and external data sources to inform these judgments. The assessment of goodwill is
sensitive to changes in these assumptions, which could materially affect the outcome of the impairment test.
At 31 December 2025, the carrying amount of goodwill is DKK 455 million (2024: DKK 463 million).
Intangible assets 2025
Goodwill
Software
Patents, trademarks and rights
Other intangible assets
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Annual Report 2025Consolidated financial statements 102
Section 3 – Operating assets and liabilities
3.2 Property, plant and equipment
Other Property, fixtures plant and Land and Plant and and equipment 1Amounts in DKKmbuildingsmachineryequipmentin progress Total 2025Cost beginning of year 2,027 1,355 315 528 4,225Currency adjustments (77) (55) (6) (10) (148)Additions 14 45 13 210 282Acquisition of companies and operations, cf. note 5.3 - - - - -Remeasurement of lease obligations (28) - - - (28)Disposals (26) (23) (14) (9) (72)Transfer to/from other groups 50 142 3 (195) -Cost year end 1,960 1,464 311 524 4,259Depreciation and impairment beginning of year 890 752 236 - 1,878Currency adjustments (18) (31) (4) - (53)Depreciation for the year 106 102 21 - 229Disposals during the year (23) (23) (14) (9) (69)Impairment during the year, cf. note 2.3 - 1 - 9 10Depreciation and impairment year end 955 801 239 - 1,995Carrying amount year end 1,005 663 72 524 2,264of which financing costsValue of land and buildings subject to mortgages 2451 Land and buildings include buildings on land leased from Scion DTU A/S, Hørsholm in Denmark. The estimated lease terms are 8 years. See also note 3.3.
Other Property, fixtures plant and Land and Plant and and equipment 1Amounts in DKKmbuildingsmachineryequipmentin progress Total 2024Cost beginning of year 1,811 1,18 2 298 596 3,887Currency adjustments 34 23 3 9 69Additions 88 17 13 219 337Acquisition of companies and operations, cf. note 5.3 2 2 - 2 6Remeasurement of lease obligations (1) - - - (1)Disposals (38) (29) (6) - (73)Transfer to/from other groups 131 160 7 (298) -Cost year end 2,027 1,355 315 528 4,225Depreciation and impairment beginning of year 817 671 218 - 1,706Currency adjustments 8 13 2 - 23Depreciation for the year 103 94 21 - 218Disposals during the year (38) (29) (6) - (73)Impairment during the year, cf. note 2.3 - 3 1 - 4Depreciation and impairment year end 890 752 236 - 1,878Carrying amount year end 1,137 603 79 528 2,347of which financing costs -Value of land and buildings subject to mortgages 2281 Land and buildings include buildings on land leased from Scion DTU A/S, Hørsholm in Denmark. The estimated lease terms are 9 years. See also note 3.3.
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Annual Report 2025Consolidated financial statements 103
Section 3 – Operating assets and liabilities
2025
45% 29% 3% 23%
3.2 Property, plant and equipment – continued
§ Accounting policies
Land and buildings, plant and machinery, and other fixtures and equipment are measured at cost less accumulated
depreciation and impairment. Land is not depreciated. Cost comprises the purchase price and any costs directly attrib-
utable to the acquisition and any preparation costs incurred until the date when the asset is available for use.
The depreciation base is cost less the estimated residual value at the end of the useful life. The residual value is deter-
mined as the amount the company expects to obtain for the asset less costs of disposal.
The cost of an asset is divided into smaller components that are depreciated separately if such components have
different useful lives.
Tangible assets are depreciated on a straight-line basis over their estimated useful lives as follows:Buildings 25-50 yearsPlant and machinery 5-10 yearsOther fixtures and equipment 5-10 years
Depreciation methods, useful lives and residual values are reassessed once a year.
Impairment
The carrying amounts of tangible assets are reviewed at the balance sheet date to determine whether there are any indi-
cations of impairment. If such indications are found, the recoverable amount of the asset is calculated to determine any
need for an impairment write-down and, if so, the amount of the write-down.
If the asset does not generate any cash flows independently of other assets, the recoverable amount is calculated for
the smallest cash-generating unit that includes the asset.
The recoverable amount is calculated as the higher of the fair value less costs to sell and the value in use of the asset or
the cash-generating unit, respectively. In determining the value in use, the estimated future cash flows are discounted
to their present value, using a discount rate reflecting current market assessments of the time value of money as well as
risks that are specific to the asset or the cash-generating unit and which have not been taken into account in the esti-
mated future cash flows.
If the recoverable amount of the asset or the cash-generating unit is lower than the carrying amount, the carrying
amount is written down to the recoverable amount. For the cash-generating unit, the write-down is allocated in such a
way that goodwill amounts are written down first, and any remaining need for write-down is allocated to other assets in
the unit, although no individual assets are written down to a value lower than their fair value less costs to sell.
Impairment write-downs are recognised in the income statement. If write-downs are subsequently reversed as a result
of changes in the assumptions on which the calculation of the recoverable amount is based, the carrying amount of the
asset or the cash-generating unit is increased to the adjusted recoverable amount, not, however, exceeding the carrying
amount that the asset or cash-generating unit would have had, had the write-down not been made.
Property, plant and equipment 2025
Land and buildings
Plant and machinery
Other fixtures and equipment
Property, plant and equipment
in progress
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Annual Report 2025Consolidated financial statements 104
Section 3 – Operating assets and liabilities
3.3 Leases
Specification of right-of-use assets:
Other Land and fixtures and 1Amounts in DKKmbuildingsequipment Total 2025Cost beginning of year 518 3 521Currency adjustments (19) - (19)Additions 6 - 6Remeasurement of lease obligations (28) - (28)Disposals (21) - (21)Cost year end 456 3 459Depreciation beginning of year 208 2 210Currency adjustments (10) - (10)Depreciation for the year 48 - 48Disposals (18) - (18)Depreciation year end 228 2 230Carrying amount year end 228 1 2291 Land and buildings include buildings on land leased from Scion DTU A/S, Hørsholm in Denmark. The estimated lease terms are 8 years.
Specification of right-of-use assets:
Other Land and fixtures and 1Amounts in DKKmbuildingsequipment Total 2024Cost beginning of year 452 3 455Currency adjustments 8 - 8Additions 77 - 77Remeasurement of lease obligations (1) - (1)Disposals (18) - (18)Cost year end 518 3 521Depreciation beginning of year 170 2 172Currency adjustments 5 - 5Depreciation for the year 51 - 51Disposals (18) - (18)Depreciation year end 208 2 210Carrying amount year end 310 1 3111 Land and buildings include buildings on land leased from Scion DTU A/S, Hørsholm in Denmark. The estimated lease terms are 9 years.
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Annual Report 2025Consolidated financial statements 105
Section 3 – Operating assets and liabilities
3.3 Leases – continued
Leases in the income statement
Amounts in DKKm 2025 2024Expenses from short-term leases 3 1Expenses from low-value assets (including cars) 21 20Depreciation of right-of-use assets 48 51Interest expenses on lease liabilities 9 9Total 81 81
Cash outflow related to lease agreements was DKK 55 million (2024: DKK 59 million).
Lease liabilities are disclosed in note 4.2.
§ Accounting policies
Lease liabilities
Lease assets are recognised at the commencement date of the contract if it is or contains a lease. Lease assets are
recognised at cost less accumulated depreciation and impairment. Cost is defined as the lease liability adjusted for any
lease payments made at or before the commencement date. Lease assets are depreciated on a straight-line basis over
the lease term.
Lease assets are remeasured when the lease liability is impacted by reassessment of lease terms, modifications to
lease agreements, and when applying indexation or a rate.
On initial recognition, lease liabilities are measured as the present value of future payments. The lease payments contain
fixed payments less any lease incentives receivable and variable lease payments that depend on an index or a rate.
On subsequent recognition, lease liabilities are measured at amortised cost. The difference between the present value
and the nominal value of lease payments is recognised in the income statement over the term of the lease as a finance
charge.
If the interest rate cannot be determined in the agreement, the lease payments are discounted using the ALK Group’s
incremental borrowing rate adjusted for the functional currency and length of the lease term. The lease liability is
remeasured if or when the future payment or lease term changes.
Short term lease expenses and low value assets are not recognised as part of lease liabilities. They are recognised in the
income statement when incurred as an operating expense.
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Section 3 – Operating assets and liabilities
38%
38%
24%
3.4 Inventories
Amounts in DKKm 2025 2024Amount of write-down of inventories during the year 63 31Raw materials 405 405Work in progress 698 649Manufactured goods and goods for resale 680 662Total 1,783 1,716Total cost of materials included in cost of sales 731 657Net carrying amount of inventory not expected to be sold in following year 1611Amount of reversal of write-down of inventories during the year 51819 161 Reversal of provision for slow moving items, sold in 2025.
§ Accounting policies
Inventories are measured at cost determined under the FIFO method or net realisable value where this is lower.
Cost comprises raw materials, goods for resale, and direct payroll costs as well as fixed and variable production
overheads. Variable production overheads comprise indirect materials and payroll costs and are allocated based
on predetermined costs of the goods actually produced. Fixed production overheads comprise maintenance of and
depreciation on the machines, factory buildings and equipment used in the manufacturing process as well as the cost
of factory management and administration. Fixed production overheads are allocated based on the normal capacity of
the production plant.
The net realisable value of inventories is calculated as the expected selling price less completion costs and costs
incurred in making the sale.
A minor part of ALK’s raw materials inventory contains biological assets from agricultural activities. Due to missing
market on which a fair value can be established these products are not valuated.
Significant accounting estimates and judgements
The valuation of inventories includes Management’s assessment of the saleability of the finished goods, and the quality
of raw materials to be used in the production process. If the expected sales price less any completion costs and costs to
execute sales (net realisable value) of inventories is lower than the carrying amount, the inventories are written down to
net realisable value. When assessing salability and net realisable value, Management uses estimates for future sales
and related costs.
End of 2025, the write-down of inventories to net realisable value amounted to DKK 152 million (2024: DKK 147 million).
Further, work in progress and manufactured goods and goods for resale are measured at cost including indirect
production costs. The indirect production costs are measured using a standard cost method. This is reviewed regularly
to ensure reliable measurement of employee costs, capacity utilisation, cost drivers and other relevant factors. When
including the indirect productions costs for capitalisation, Management makes estimates about cost of production,
standard cost variances, cost drivers and capacity utilisation. Changes in these parameters may have a significant
impact on the gross margin and the overall valuation of work in progress and manufactured goods and goods for resale.
At the end of 2025, the indirect production costs capitalised under inventories amounted to DKK 546 million (2024: DKK
554 million).
Inventories 2025
Raw materials
Work in progress
Manufactured goods and
goods forresale
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Section 3 – Operating assets and liabilities
3.5 Trade receivables
Days past dueAmounts in DKKm Not due <180 days 180-360 >360 days Total2025Average expected credit loss rate 0% 2% 25% 33%Trade receivables (gross) 989 104 4 2 1,099Loss allowance 2 2 1 1 6Trade receivables (net) 1,093Loss allowance:Balance beginning of year 16Currency adjustments (1)Change in allowances during the year (6)Realised losses during the year (3)Loss allowance, year end 62024Average expected credit loss rate 1% 5% 20% 33%Trade receivables (gross) 739 81 5 3 828Loss allowance 10 4 1 1 16Trade receivables (net) 729 77 4 2 812Loss allowance:Balance beginning of year 7Change in allowances during the year 11Realised losses during the year (2)Loss allowance, year end 16
§ Accounting policies
On initial recognition, receivables are measured at fair value, subsequently at amortised cost.
Expected credit losses are measured based on historical data adjusted by forward-looking information. Forward-
looking information includes assessment of the probability of default as well as consideration of various external
sources of actual and economic information that is reasonable and supportable without undue cost or effort.
ALK recognises expected credit losses that result from default events possible within the whole asset life. Risk related to
trade receivables is managed in ALK locally by entities, based on an individual assessment. Loss allowance for doubtful
trade receivables is also based on an individual assessment of the receivables. ALK has not implemented a global provi-
sion matrix due to different characteristics related to receivables across the ALK Group. Loss allowance are calculated
based on variables, e.g. probability-weighted amount (based on historical realised losses), the time value of money,
additional supportable information, including an individual assessment of each customer/customer group.
An impairment loss or reversal of prior impairment loss is recognised in the income statement.
Receivables are written down when information indicates severe financial difficulties and that there is no reasonable
expectation of recovery. Financial assets written off may still be subject to enforcement activities. Any recoveries made
are recognised in the income statement.
3.6 PrepaymentsAmounts in DKKm 2025 2024Clinical trials, cf. note 2.2 42 20Royalties - 25Other 90 73Total 132 118
§ Accounting policies
Prepayments are recognised as an asset and comprise incurred costs relating to subsequent financial years. Prepay-
ments are measured at cost.
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Section 3 – Operating assets and liabilities
3.7 Pensions and similar liabilities
The ALK Group has entered into defined contribution plans as well as defined benefit plans.
In defined contribution plans, the ALK Group is obliged to pay a certain contribution to a pension fund
or the like but bears no risks regarding the future development in interest, inflation, mortality, disability
rates ,etc. regarding the amount to be paid to the employee.
The ALK Group sponsors defined benefit plans for qualifying employees of its subsidiaries in Germany,
France and Switzerland. The defined benefit plans guarantee employees a certain level of pension bene-
fits for life. The pension is based on seniority and salary at the time of retirement. The ALK Group bears the
risks regarding the future development in interest, inflation, mortality, disability rates, etc. regarding the
amount to be paid to the employee.
Amounts in DKKm 2025 2024Costs related to defined contribution plans 120 125Costs related to defined benefit plans 25 26Total 145 151Present value of funded pension obligations 27 26Fair value of plan assets (100% insurance contract) (23) (22)Funded pension obligations, net 4 4Present value of unfunded pension obligations 163 172Pension obligations 167 176Anniversary liabilities 12 111Other liabilities65 64Pension obligations and similar liabilities, year end 244 2511 Other liabilities include liability related to the transition period for the Danish Holiday Act of DKK 63 million (2024: DKK 62 million).
Plan assets consist of assets placed in pension companies. Assets are placed in investments classified
as other assets than shares, bonds and property by the pension companies, and are not measured at
quoted prices.
The weighted average duration of the pension obligations is 14.94 years (2024: 15.78 years).
)
Amounts in DKKm 2025 2024The principal assumptions used for the actuarial valuationsDiscount rate range of 1.1% - 4.05% (weighted average rate) 4.0% 3.4%Expected future rate of salary increase range of 1% - 2.5% (weighted average rate) 2.4% 2.4%Assumed life expectations on retirement age for current pensioners1(years based on weighted average): Males 20.1 2 0.1 Females 23.1 23.1Assumed life expectations on retirement age for current employees 1(future pensioners) (years based on weighted averag: Males 21.2 21.2 Females 24.9 24.8Sensitivity analysis:Significant actuarial assumptions for determining the defined benefit obligation2Discount rate, effect in case of increase in range of 0.25% - 1%(20) (22)2Discount rate, effect in case of decrease in range of 0.25% - 1%24 272Salary, effect in case of 0.25% - 0.5% increase2 32Salary, effect in case of 0.25% - 0.5% decrease(2) (2)1Life expectancy, effect in case of increase by 1 year6 61Life expectancy, effect in case of decrease by 1 year(6) (7)Movements in the present value of the funded defined benefit obligation in the current yearOpening funded defined benefit obligation 26 24Current service costs 2 2Actuarial (gains)/losses arising from changes in financial assumptions - 3Actuarial (gains)/losses arising from experience adjustments (1) (1)Contribution from plan participants 1 -Benefits paid (2) (1)Currency translation adjustment 1 (1)Closing funded defined benefit obligation 27 261 Based on national statistics for mortality. 2 Based on actuarial reports with different rates.
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Section 3 – Operating assets and liabilities
3.7 Pensions and similar liabilities – continued
Amounts in DKKm 2025 2024Movements in the fair value of the plan assets in the current yearOpening fair value of plan assets 22 22Contribution from plan participants 3 2Benefits paid (2) (1)Currency translation adjustment 1 -Return on plan assets (1) (1)Closing fair value of plan assets (fully invested in insurance contracts) 23 22Movements in present value of unfunded pension obligations in the current yearOpening present value of unfunded pension obligations 172 171Current service costs 4 5Interest costs 6 6Actuarial (gains)/losses from changes in financial assumptions (14) (2)Actuarial (gains)/losses arising from experience adjustments 1 (2)Actuarial (gains)/losses arising from demographic adjustments - (1)Benefits paid (6) (5)Closing present value of unfunded pension obligations 163 172Amount recognised as staff expenses in the income statementCurrent service costs 6 6Net interest expense 6 6Total 12 12Amount recognised in comprehensive income in respect of defined benefit plans Actuarial (gains)/losses (13) (3)Total (13) (3)
The expected contribution for 2026 for the defined benefit plans is DKK 13 million (2025: DKK 12 million).
The most recent actuarial valuations of the defined benefit liability were carried out by external inde-
pendent actuary agents at 31 December 2025.
§ Accounting policies
The ALK Group has entered into pension agreements and similar agreements with some of the ALK Group’s employees.
In respect of defined contribution plans, the ALK Group pays in fixed contributions to independent pension funds, etc.
The contributions are recognised in the income statement during the period in which the employee renders the related
service. Payments due are recognised as a liability in the balance sheet.
In respect of defined benefit plans, the ALK Group is required to pay an agreed benefit in connection with the retirement
of the employees covered by the plan, e.g. in the form of a fixed amount or a percentage of the salary at retirement.
For defined benefit plans, an annual actuarial assessment is made of the net present value of future benefits to which the
employees have earned the right through their past service for the ALK Group and which will have to be paid under the
plan. The Projected Unit Credit Method is applied to determine net present value.
The net present value is calculated based on assumptions of the future development of salary, interest, inflation,
mortality and disability rates.
The net present value of pension liabilities is recognised in the balance sheet, after deduction of the fair value of any
assets attached to the plan, as either plan assets or pension liabilities, depending on whether the net amount is an asset
or a liability, as described below.
If the assumptions made with respect to discount factor, inflation, mortality and disability are changed, or if there is a
discrepancy between the expected and realised return on plan assets, actuarial gains or losses occur. These gains and
losses concerning previous financial years are recognised in other comprehensive income.
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Section 3 – Operating assets and liabilities
38%
14%
21%
3%
24%
3.8 Provisions
Restructuring Other 1provisions2Amounts in DKKmprogramsTotal2025Provisions beginning of year 23 16 39Provisions made during the year - 13 13Used during the year (22) (6) (28)Reversals during the year - (3) (3)Provisions, year end 1 20 21Provisions are recognised as follows: Non-current liabilities - 1 1Current liabilities 1 19 20Provisions, year end 1 20 212024Provisions beginning of year - 3 3Provisions made during the year 63 13 76Used during the year (40) - (40)Provisions, year end 23 16 39Provisions are recognised as follows: Non-current liabilities - 1 1Current liabilities 23 15 38Provisions, year end 23 16 391 The restructuring provision of DKK 1 million in 2025 relates to the implementation of restructuring initiatives recognised in 2024. During 2025, DKK 22 million of the provision was utilised in line with the intended purpose.2 Other provisions in 2025 include a provision for sales in Italy of DKK 10 million (2024: DKK 8 million) and provisions for legal proceedings of DKK 10 million (2024: DKK 8 million).
§ Accounting policies
Provisions are recognised when, as a consequence of a past event during the financial year or previous years, the ALK
Group has a legal or constructive obligation, and it is likely that settlement of the obligation will require an outflow of the
ALK Group’s financial resources. Provisions are measured as the best estimate of the costs required to settle the obliga-
tions at the balance sheet date. Provisions with an expected term of more than a year after the balance sheet date are
measured at present value.
3.9 Other payables
Amounts in DKKm 2025 2024Rebates and commissions, cf. note 2.1 314 208Salaries, holiday payments, etc. 357 337Clinical trials, cf. note 2.2 50 24VAT and other indirect taxes 165 123Other payables 170 190Total 1,056 882
§ Accounting policies
Other payables are recognised as a current liability and comprise costs due in the subsequent financial year. Other
payables are measured at amortised cost.
Other payables 2025
Rebates and commissions
Salaries, holiday payments, etc.
Clinical trials
VAT and other indirect taxes
Other payables
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Section 3 – Operating assets and liabilities
3.10 Contingent liabilities and commitments
Contingent liabilities
In the ordinary course of business, the ALK Group is involved in certain claims, disputes etc. In the opinion
of Management, settlement or continuation of pending claims and other disputes will have no material
impact on the ALK Group’s financial position.
The ALK Group operates in a wide variety of jurisdictions, in some of which the tax law is subject to varying
interpretations and potentially inconsistent enforcement. As a result, there can be practical uncertainties
in applying tax legislation to the ALK Group’s activities. Whilst the ALK Group considers that it operates
in accordance with applicable tax law, there are potential tax exposures in respect of its operations, the
impact of which cannot be reliably estimated, but could be material.
Joint taxation scheme
ALK-Abelló A/S is included in a joint Danish taxation scheme with the Lundbeck Foundation (Lundbeck-
fond Invest A/S) and its Danish subsidiaries. The Danish companies are joint and several liable for the
joint taxation liability. The joint taxation liability covers income taxes and withholding taxes on dividends,
royalties and interest. The joint taxation liability is capped at an amount equal to the share of the capital
of the company directly or indirectly owned by the ultimate parent company. The total tax obligation
under the joint Danish taxation scheme is shown in the financial statements of the Lundbeck Foundation
(Lundbeckfond Invest A/S).
Change of control
The ALK Group’s credit facilities and drawn loans are subject to standard change of control clauses
according to which the lender has the right to cancel the commitment and demand repayment of
outstandings.
Security in assets
Land and buildings provided as security vis-à-vis for mortgage debt amount to DKK 245 million
(2024: DKK 228 million). Mortgage debt amounts to DKK 168 million (2024: DKK 185 million).
Commitments
Amounts in DKKm 2025 20241Bank guarantees80 80Other guarantees 19 16Total 99 961 Bank guarantees include DKK 78 million related to ongoing tax audits (2024: DKK 78 million).
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Section 4 – Capital structure and financing
4.1 Share capital and earnings per share
2025 2024NominalNominalvaluevalueUnits(DKKm) Units(DKKm)Share capitalThe share capital consists of:A shares (nominal value of DKK 0.5) 18,415,200 9 18,415,200 9AA shares (nominal value of DKK 0.5) 1,841,520 1 1,841,520 1B shares (nominal value of DKK 0.5) 202,567,200 101 202,567,200 101Total 222,823,920 111 222,823,920 111
Each A and AA share carries 10 votes, whereas each B share carries 1 vote. AA shares no longer held by
individuals or legal entities other than the Lundbeck Foundation or companies which are group affiliated
with the Lundbeck Foundation, cf. the definition of groups in section 6 of the Danish Companies Act, or in
the event that a company which holds AA shares is no longer group affiliated with the Lundbeck Founda-
tion, such AA shares shall be transferred to the B share capital.
According to a resolution passed by the parent company at the annual general meeting, the parent
company is allowed to purchase treasury shares, up to 10% of the share capital. The parent company
has purchased treasury shares in connection with the issuance of share-based incentive plans. All shares
are paid in.
2025 2024Treasury sharesTreasury shares beginning of year (B-shares), units 1,423,497 1,634,673Sale of treasury shares, units (162,214) (211,176)Treasury shares year end (B-shares), units 1,261,283 1,423,497Proportion of share capital year end 0.6% 0.6%Nominal value year end (DKKm) 0.6 0.7Market value year end (DKKm) 288 226Earnings per shareThe calculation of earnings per share is based on the following:Net profit (DKKm) 1,197 815Number in units:Average number of issued shares 222,823,920 222,823,920Average number of treasury shares (1,298,717) (1,505,851)Average number of shares used for calculation of earnings per share 221,525,203 221,318,069Average dilutive effect of outstanding share options 285,750 225,765Average number of shares used for calculation of diluted earnings per share 221,810,953 221,543,834Earnings per share (EPS) (DKK) 5.40 3.68Earnings per share, diluted (DEPS) (DKK) 5.40 3.68
§ Accounting policies
Acquisition and sales sums arising on the purchase and sale of treasury shares and dividends on treasury shares are
recognised directly in retained earnings under equity.
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Section 4 – Capital structure and financing
4.2 Financial risks and financial instruments
Financial risk management policy
As a result of operations, investments and financing, the ALK Group is exposed to exchange and interest
rate changes. ALK-Abelló A/S manages the ALK Group’s financial risks centrally and coordinates the ALK
Group’s cash management, including the raising of capital and investment of excess cash. The ALK Group
complies with a policy, approved by the Board of Directors, to maintain a low risk profile, ensuring that the
ALK Group is only exposed to foreign exchange rate risk, liquidity risk, interest rate risk, and credit risk in
connection with its commercial activities.
Capital structure
The ALK Group manages its capital to ensure that all entities will be able to continue as going concern
while maximising the return to stakeholders through the optimisation of the debt and equity balances.
The capital structure of the ALK Group consists of net debt and equity. The ALK Group will maintain an effi-
cient capital structure with a financial gearing of maximum 2 x NIBD/EBITDA. The ALK Group will be disci-
plined about capital allocation to ensure flexibility to deliver on its growth ambitions while also gener-
ating attractive shareholder returns. Cash will be allocated in the following order of priority: Investments
in organic growth, including R&D; CAPEX; business development and licensing activities; and finally, cash
distribution to shareholders via dividends and/or share buyback programmes. The dividend policy of the
ALK Group is to distribute maximum possible dividend to ALK-Abelló A/S.
The ALK Group’s Risk Committee reviews the capital structure annually. As a part of this review, the
committee considers the cost of capital and the risks associated with each class of capital.
Foreign exchange rate risk
Foreign exchange rate risk arises due to imbalances between revenue and expenses in each individual
currency. Foreign exchange rate exposure relating to future transactions and assets and liabilities is
evaluated and hedged through matching of payments received and paid in the same currency. This
serves to limit the impact on the financial results of any exchange rate fluctuations. The exchange
rate exposure relating to net investments in foreign subsidiaries is not hedged by forward exchange
contracts. In case it is evaluated to be relevant, the ALK Group hedges significant exchange rate expo-
sures regarding future sales and purchase of goods in the coming six months in accordance with the ALK
Groups policy.
The general objective of the ALK Group’s foreign exchange risk management is to limit and delay any
adverse impact of exchange rate fluctuations on earnings and cash flows and thus increase the predict-
ability of the financial results. The most significant financial risk relates to exchange rate fluctuations. The
greatest exposure is to USD and in 2025, 14% (2024: 14%) of the revenue was denominated in USD. The
sales are not deemed to be exposed to EUR due to Denmark’s participation in the European Exchange
Rate Mechanism.
The ALK Group is exposed to exchange rate risks when intercompany balances and net assets of foreign
subsidiaries are translated into DKK. In accordance with the ALK Group’s accounting policies, such
currency translation adjustments are recognised in the income statement and in other comprehensive
income, respectively.
No exchange rate hedge contracts were open at 31 December 2025 or 31 December 2024.
Sensitivity to a 10% increase in USD exchange rate
The table below shows the estimated effect of a 10% increase in the USD exchange rate on revenue, EBIT
and equity levels, respectively. A decrease in the exchange rates will have a corresponding adverse
effect. In the sensitivity analysis, data for revenue and EBIT are based on current short-term expectations
and data for equity are based on actual equity at 31 December 2025.
Amounts in DKKm Revenue EBIT Net profit Equity 31 December 2025USD approx. +110 approx. +10 approx. +10 approx. +3531 December 2024USD approx. +95 approx. +10 approx. +10 approx. +25
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Section 4 – Capital structure and financing
4.2 Financial risks and financial instruments – continued
Net positions
Amount Net Amounts in DKKm Cash Receivables Liabilitieshedgedposition 31 December 2025DKK 21 137 (962) - (803)USD 168 225 (224) - 169EUR 855 648 (1,14 0) - 363GBP 23 35 (48) - 10SEK 18 52 (22) - 48Other 155 249 (175) - 228Total 1,240 1,346 (2,571) - 1531 December 2024DKK 5 47 (744) - (692)USD 164 152 (283) - 33EUR 279 373 (1,632) - (980)GBP 12 29 (35) - 6SEK 18 32 (21) - 29Other 111 264 (158) - 217Total 589 897 (2,873) - (1,387)
Liquidity risk
In connection with the ALK Groups ongoing financing of operations, including refinancing, efforts are
made to ensure adequate and flexible liquidity. This is guaranteed by placing free funds in credit-worthy,
liquid, interest bearing instruments of relatively short durations in accordance with the ALK Group’s
policy. The ALK Group has not entered into any supplier finance arrangements in 2025 or 2024.
The liquidity risk is considered to be minimal due to the ALK Group’s current capital structure.
Liquidity exposure
Revaluation/payment dateCarrying Total Within From After Amounts in DKKmamountcash flow11 year1-5 years5 years 31 December 2025Mortgage debt and bank loans 168 168 17 71 80Trade payables 140 140 140 - -Lease liabilities 250 280 46 204 30Other financial liabilities 1,095 1,095 1,095 - -Financial liabilities 1,653 1,683 1,298 275 11031 December 2024Mortgage debt and bank loans 856 862 696 74 92Trade payables 165 165 165 - -Lease liabilities 331 372 55 163 154Other financial liabilities 1,006 1,006 1,006 - -Financial liabilities 2,358 2,405 1,922 237 2461 Total cash flow includes interest.
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Section 4 – Capital structure and financing
4.2 Financial risks and financial instruments – continued
Interest rate risk
The ALK Group does not hedge its interest rate exposure, as this is not considered to be financially viable.
Concerning the ALK Group’s financial assets and financial liabilities, the earlier of the contractual revalu-
ation and redemption date is applied. Effective interest rates are stated on the basis of the current level
of interest rates on the balance sheet date.
Interest rate exposure
Carrying Fixed/ Effective Amounts in DKKmamount Currency Expiry datefloatinginterest rate 31 December 2025Cash 1,240 Various Floating (0.55)-3.72Interest-bearing assets 1,240Mortgage debt 168 DKK 2035 Floating 0.2Lease liabilities 250 Various 2026-2038 Fixed 2.0Bank loans - Various N/A Fixed N/AInterest-bearing liabilities 41831 December 2024Cash 589 Various Floating (0.25)-5.15Interest-bearing assets 589Mortgage debt 185 DKK 2035 Floating 0.2Lease liabilities 331 Various 2025-2038 Fixed 2.0Bank loans 671 Various 2025 Fixed 3.6Interest-bearing liabilities 1,187
An increase in the interest rate of 1 percentage point on mortgage debt and bank loans would decrease
net profit and equity by approximately DKK 2 million (2024: decrease of DKK 9 million). An increase in the
interest rate of 1 percentage point on cash would increase net profit and equity by approximately DKK 12
million (2024: increase of DKK 6 million).
Credit risk
The ALK Group’s primary credit exposure is related to trade receivables and cash. The ALK Group has
no major exposure relating to one single customer or business partner. According to the ALK Group’s
policy for assuming credit exposure, all customers and business partners are credit rated regularly.
Trade receivables are monitored at the local level and are distributed across a number of markets and
customers. Therefore, the credit risk is considered to be low. For more information, see note 3.5.
Embedded derivative financial instruments
The ALK Group has made a systematic review of contracts that might contain terms that would make the
contract or parts thereof a derivative financial instrument. The review did not lead to recognition of deriv-
ative financial instruments relating to the contracts.
§ Accounting policies
Financial assets
On initial recognition, investments and other financial assets are measured at cost, corresponding to fair value. They are
subsequently measured at fair value either through the income statement or through comprehensive income.
Financial liabilities
Other financial liabilities, including bank loans, lease liabilities, trade payables, and other payables, are on initial recog-
nition measured at fair value. The liabilities are subsequently measured at amortised cost.
Debt
Trade payables, other payables, including sales discounts and rebates as well as debt to public authorities, etc., are
measured at amortised cost.
Mortgage debt
Mortgage debt is recognised on the raising of a loan at cost, equalling fair value of the proceeds received, and net of
transaction costs incurred. Subsequently, mortgage debt is measured at amortised cost.
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Section 4 – Capital structure and financing
4.2 Financial risks and financial instruments – continued
Categories of financial instruments
Amounts in DKKm 2025 2024Financial assetsFinancial assets measured at amortised cost Impairment methodPrepayments 12m ECL 48 26Trade receivables Lifetime ECL (simplified approach) 1,093 812Other receivables 12m ECL 120 49Cash 1,240 589Total 2,501 1,476Financial liabilitiesFinancial liabilities measured at amortised costMortgage debt 168 185Bank loans - 671Lease liabilities 250 331Trade payables 140 165Other payables 1,056 882Total 1,614 2,234
Measurement and fair value hierarchy
Revaluation/payment dateFair Within From After Amounts in DKKmvalue1 year1-5 years5 years 31 December 2025Mortgage debt 168 17 71 80Total 168 17 71 8031 December 2024Mortgage debt 187 19 74 94Bank loans 671 671 - -Total 858 690 74 94All financial assets and liabilities are measured at cost or amortised cost. The carrying amounts for these
approximate fair value.
Fair value for mortgage debt is measured by level 1 input (quoted prices in active markets) from the
fair value hierarchy and fair value for bank loans is measured by level 2 input (inputs other than quoted
markets that are observable) from the fair value hierarchy.
No financial derivatives were used in 2025 or 2024.
Financial resources
The ALK Group has a DKK 1,500 million credit facility which runs until 2026. By the end of 2025, DKK 0 was
drawn.
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Section 5 – Other disclosures
5.1 Share-based payments
The ALK Group has established long-term equity-based incentive plans linked to the creation of share-
holder value and the fulfilment of strategic goals. The plans are established for the members of Board
of Management and other key employees, reward long-term value creation, and align to interests of the
shareholders.
The incentive plans consist of share options, performance share units, and restricted stock units that are
considered sufficiently covered by treasury shares.
The share options entitle the holder to acquire one existing B share of DKK 0.5 nominal value in the
company per share option. The performance share units and restricted stock units entitle the holder to
receive one existing B share per performance share unit or restricted stock unit free of charge.
The vesting period for both share options, performance share units, and restricted stock units is three
years after grant. Vesting of share options and performance share units is conditional upon certain
targets being met and upon the participant not having resigned. Target achievement is met upon fulfil-
ment of strategic key performance indicators. In case performance is below the threshold there will be
no units vesting, and if above target, a multiplier is applied that can increase the vesting by up to 100%.
Vesting of restricted stock units is conditional upon continued employment.
The exercise of share options is possible in the trading windows following the release of annual and
interim reports conditional upon the share option holder not having resigned at the time of exercise. For
performance share units and restricted stock units, the final transfer of ownership takes place at vesting
three years after the grant.
From the 2023 plans and onwards, a cap applies to the maximum total value gain from share options,
performance shares, and restricted stock units at exercise and/or vesting, respectively, granted in a
calendar year. The cap is four times the annual base salary at the time of award of the share options,
performance share units, and restricted stock units concerned.
Expensed in the income statement:
Amounts in DKKm 2025 2024Cost for the year regarding share-based payments is recognised as follows:Cost of sales 9 10Research and development expenses 8 9Sales and marketing expenses 12 13Administrative expenses 16 16Financial expenses - 3Total 45 51
In 2025, the total cost of share-based payments included a financial expense of DKK 0 million due to the
exercise and cash settlement of share options (2024: Financial income of DKK 3 million). The total cost
included DKK 18 million related to adjustment in the share options and performance share units (2024:
DKK 22 million).
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Annual Report 2025Consolidated financial statements 118
Section 5 – Other disclosures
5.1 Share-based payments – continued
Specification of outstanding share options, performance share units, and restricted stock units:
Restricted Share options Performance share unitsstock unitsWeighted Board of Other key average Board of Other key Board of Management employees Total exercise price Management employees Total ManagementunitsunitsunitsDKKunitsunitsunitsunits2025Outstanding at 1 January 432,221 294,274 726,495 109 62,030 344,622 406,652 151,997Additions 41,552 61,698 103,250 140 36,857 102,460 139,317 -Exercised/settled - (182,714) (182,714) 139 (4,060) (115,24 0) (119,30 0) -Change in Board of Management (59,23 4) 59,234 - - (12,511) 12,511 - -Cancellations (7,287 ) - (7,287) - (6,479) (4,681) (11,16 0) -Outstanding at 31 December 407, 252 232,492 639,744 105 75,837 339,672 415,509 151,997Total number of vested share options 47,02 2Average remaining life at year end (years) 4,3Exercise prices at year end (DKK) 104-1482024Outstanding at 1 January 487,811 766,268 1,254,079 95 28,263 3 87,116 415,379 151,997Additions 49,94 5 116,28 6 166,231 126 39,983 154,125 194,10 8 -Exercised/settled (105,535) (588,280) (693,815) 92 (6,216) (175,980) (18 2,196) -Cancellations - - - - - (20,639) (20,639) -Outstanding at 31 December 432,221 294,274 726,495 109 62,030 344,622 406,652 151,997Total number of vested share options 103,656Average remaining life at year end (years) 4.3Exercise prices at year end (DKK) 76-148
The Board of Directors decided for three trading windows in 2025 to settle share options by cash and a total of 270,970 share options were exercised and total cash payments amounted to DKK 20 million.
In 2025 the Board of Directors decided not to settle share options by shares and no share options were exercised.
The Board of Directors decided for two trading windows in 2024 to settle share options by cash and a total of 616,647 share options were exercised and total cash payments amounted to DKK 33 million. For two
trading windows in 2024 the Board of Directors decided to settle share options by shares and a total of 77,168 share options were exercised.
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Annual Report 2025Consolidated financial statements 119
Section 5 – Other disclosures
5.1 Share-based payments – continued
Outstanding share options, performance share units and restricted stock units have the following char-
acteristics:
Performance Restricted Share optionsshare unitsstock unitsAverage exercise Exercise price Vested period Vested Vested Plan UnitsDKKas per (years) Unitsas per Unitsas per2021 Plan - 128 1 Mar 2024 2 1 Mar 20242022 Plan 47,02 2 154 1 Mar 2025 2 1 Mar 20252023 Plan 84,433 104 1 Apr 2026 4 148,408 1 Apr 20262023 Plan, special 323,519 82 1 Jun 2026 42023 Plan, special 21,925 1 Mar 20262023 Plan, special 130,072 1 Nov 20262024 Plan 86,273 126 1 Apr 2027 4 133,14 0 1 Apr 20272025 Plan 98,497 140 1 Apr 2028 4 133,961 1 Apr 2028Outstanding at 31 December 639,744 415,509 151,997
Fair value of share options, performance share units, and restricted stock units granted:
Share options
Fair value at grant date is measured in accordance with the Black & Scholes model for valuation of share
options, using the following assumptions: 2025 2024 PlanPlanAverage share price (DKK) 140 126Expected exercise price (DKK) 140 126Expected volatility rate, based on the historical volatility 40 % p.a. 40% p.a.Expected option life 5 years 5 yearsExpected dividend per share - -Risk-free interest rate 2,13% p.a . 2.29% p.a.Calculated fair value of granted share options (DKK) 53 48
Performance share units
In 2025, performance share units have been granted at DKK 140 per share (2024: DKK 126 per share).
Restricted stock units
No restricted stock units were granted in 2025 or 2024.
§ Accounting policies
Share-based incentive plans (equity-settled share-based payments), which comprise share options, performance
share units, and restricted stock units are measured at the grant date at fair value and recognised in the income state-
ment under the respective functions over the vesting period and offset in equity.
The fair value of share options is determined using the Black & Scholes model. The exercise price is equivalent to the
average market price of the share for the five trading days immediately preceding the date of grant. For 2023 and later
share option plans the exercise price is reduced by dividends paid. For share option plans before 2023 the exercise price is
increased by 2.5% p.a. and reduced by dividends paid.
The fair value of performance share units and restricted stock units is determined using the average share price (closing)
five days after annual general meeting.
The ALK Group settles the equity-settled share-based incentive plans in shares. However, the share option agreement
entitles the ALK Group to demand cash settlement of the options. The ALK Group recognises share options, in case of
cash settlement, as other liabilities and adjusts to fair value as from the time when the ALK Group has an obligation to
settle in cash. The ALK Group recognises subsequent adjustment to fair value in the income statement under financial
income or financial expenses.
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Annual Report 2025Consolidated financial statements 120
Section 5 – Other disclosures
5.2 Cash flow
Adjustment for non-cash items
Amounts in DKKm 2025 2024Tax on profit 438 242Financial income and expenses 19 34Share-based payments 45 51Depreciation, amortisation and impairment 328 272Other adjustments - 41Total 830 640
Changes in working capital
Amounts in DKKm 2025 2024Change in inventories (126) (272)Change in receivables and prepayments (389) 78Change in short-term payables 366 43Total (149) (151)
Reconciliation of liabilities arising from financing activities
Amounts in DKKm 2025 2024Liabilities from financing activities at 1 January 1,187 765Proceeds from borrowings - 671Repayment of borrowings (688) (279)Lease additions and modifications (22) 76Instalments of lease liabilities (46) (50)Exchange rate adjustments (13) 4Liabilities from financing activities at 31 December 418 1,187
Financial reserves
Amounts in DKKm 2025 2024Cash 1,240 589Undrawn facilities 1,500 829Total 2,740 1,418
ALK has a DKK 1,500 million credit facility which runs until 2026. By the end of 2025, DKK 0 was drawn.
§ Accounting policies
Cash flow
The cash flow statement of the ALK Group is presented using the indirect method and shows cash flows from operating,
investing and financing activities as well as cash at the beginning and at the end of the financial year.
The cash effect of acquisitions and divestments is shown separately under cash flows from investing activities. In the cash
flow statement, cash flows concerning acquired companies are recognised from the date of acquisition, while cash flows
concerning divested companies are recognised until the date of divestment.
Cash flows from operating activities are stated as net profit, adjusted for non-cash operating items and changes in
working capital, less the income tax paid and plus net financial items.
Cash flows from investing activities comprise payments in connection with acquisition and divestment of companies and
financial assets as well as purchase, development, improvement and sale of intangible and tangible assets.
Cash flows from financing activities comprise changes to the parent companys share capital and related costs as
well as the raising and repayment of loans, instalments on interest-bearing debt, lease liabilities, purchase of treasury
shares, and settlement of share options and payment of dividends.
Cash flows in currencies other than the functional currency are recognised in the cash flow statement using average
exchange rates for the individual months if these are a reasonable approximation of the actual exchange rates at the
transaction dates. If this is not the case, the actual exchange rates for the specific days in questions are used.
Cash comprise cash subject to an insignificant risk of changes in value less any overdraft facilities that are an integral
part of the ALK Group’s cash management.
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Annual Report 2025Consolidated financial statements 121
Section 5 – Other disclosures
5.3 Business combinations
No companies or operations were acquired in 2025.
DKK 10 million of contingent considerations, related to 2024 acquisitions, was paid in 2025.
On 2 January 2024, the ALK Group acquired the operating assets of AllerQuest for a total cash consider-
ation of DKK 125 million. The consideration amount included an escrow amount of DKK 10 million which
served as reserve for potential indemnifications over 18 months from acquisition date.
AllerQuest was a U.S.-based company dedicated to manufacturing PRE-PEN
®
Skin Antigen Test. This
acquisition makes ALK the sole manufacturer and distributor of PRE-PEN in the U.S. and Canada, with
global ownership rights to all assets of AllerQuest. PRE-PEN is the only FDA-approved diagnostic skin test
for the evaluation of penicillin allergy and is indicated for the assessment of sensitisation to penicillin in
patients suspected to have clinical penicillin hypersensitivity.
AllerQuest was previously a supplier of the ALK Group and integration was completed in 2024.
The transaction was on a debt and cash free basis. No liabilities were transferred.
Consolidated fair values of acquisitions:
Amounts in DKKm 2024Tangible assets and inventory 7 Product rights 118 Acquisition cost 125 Contingent considerations (10)Cash acquisition cost 115
§ Accounting policies
Newly acquired or newly established companies or operations are recognised in the consolidated financial statements
from the date of acquisition or establishment. The date of acquisition is the date when control of the company actually
passes to the ALK group.
Acquisitions are accounted for using the purchase method, according to which the identifiable assets, liabilities and
contingent liabilities of companies acquired are measured at fair value at the date of acquisition.
Restructuring costs are only recognised in the takeover balance sheet if they represent a liability to the acquired
company. The tax effect of revaluations is taken into account.
The cost of a company is the fair value of the consideration paid. If the final determination of the consideration is condi-
tional on one or more future events, these are recognised at their fair value as of the acquisition date.
Costs that can be attributed directly to the transfer of ownership are recognised in the income statement when they are
incurred. As a general rule, adjustments to estimates of conditional consideration are recognised directly to the income
statement.
If the fair value of the acquired assets or liabilities subsequently proves different from the values calculated at the acqui-
sition date, cost is adjusted for up to 12 months after the date of acquisition.
Any excess of the cost of an acquired company over the fair value of the acquired assets, liabilities and contingent liabili-
ties (goodwill) is recognised as an asset under intangible assets and tested for impairment at least once a year.
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Annual Report 2025Consolidated financial statements 122
Section 5 – Other disclosures
5.5 Events after the reporting period
No events have occured after the reporting period, that influence the evaluation of the consolidated
financial statements.
5.6 Approval of financial statements
The financial statements were approved by the Board of Directors and authorised for issue on 20
February 2026.
5.4 Related parties
Related party exercising control
ALK-Abelló A/S is controlled by the Lundbeck Foundation (Lundbeckfond Invest A/S) domiciled in Copen-
hagen, Denmark, which holds 67.2% of the total number of votes in ALK Abelló A/S. The remaining shares
are widely held. ALK-Abelló A/S is parent company, and ultimate parent for the ALK Group is the Lundbeck
Foundation (Lundbeckfond Invest A/S, incorporated in Denmark).
Other related parties comprise ALK’s Board of Management and Board of Directors, companies in which
the majority shareholder exercises control, and such companies’ subsidiaries, in this case e.g, H. Lund-
beck A/S and Falck A/S and their subsidiaries.
Transactions and balances
Transactions with the parent company’s majority shareholder:
ALK-Abelló A/S received DKK 179 million (2024: DKK 3 million) concerning outstanding company tax
from the Lundbeck Foundation (Lundbeckfond Invest A/S). The company tax relates to ALK-Abelló A/S
and ALK-Abelló Nordic A/S.
Receivables from group companies to ALK-Abelló A/S relate to outstanding company tax of DKK 118
million (2024: DKK 0) covering ALK-Abelló A/S.
Transactions with key management personnel consist of remuneration and exercise of share options, see
notes 2.4 and 5.1 of the consolidated financial statements.
No other transactions have taken place during the year with Board of Directors, Board of Management,
major shareholders or other related parties.
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Annual Report 2025Consolidated financial statements 123
Section 5 – Other disclosures
5.7 List of companies in the ALK Group
Activity
Production
Sales and distribution
Research and development
Services
Percentage of Entity Countryshares owned ActivityParent companyALK-Abelló A/S Denmark Subsidiaries by geographical areaEuropeALK-Abelló Allergie-Service GmbH Austria 100% ALK-Abelló Nordic A/S Denmark 100% ALK-Abelló Nordic A/S (branch) Finland 100% ALK-Abelló Nordic A/S (branch) Norway 100% ALK-Abelló Nordic A/S (branch) Sweden 100% ALK S.A.S. France 100% ALK-Abelló Arzneimittel GmbH Germany 100% ALK-Abelló B.V.* Netherlands 100% ALK-Abelló Sp. z o.o. Poland 100% ALK Slovakia s.r.o. Slovakia 100% ALK Slovakia s.r.o. – odšt ˇepný závod (branch) Czech Republic 100% ALK Slovakia s.r.o. Magyarországi Fktelepe (branch) Hungary 100% ALK-Abelló S.A. Spain 100% ALK-Abelló S.p.A. Italy 100% ALK AG (In liquidation) Switzerland 100% ALK-Abelló AG Switzerland 100% ALK-Abelló Ltd. United Knigdom 100% 1 Exemption for local audit of the 2025 accounts under the ruling of the Article 2:403 of the Dutch Civil Code is intended – Btw-nr. NL005302766B01
Percentage of Entity Countryshares owned ActivityNorth AmericaALK-Abel Pharmaceuticals, Inc. Canada 100% ALK-Abelló, Inc. USA 100% OKC Allergy Supplies, Inc. USA 100% ALK-Abelló Source Materials, Inc. USA 100% International marketsALK-Abelló A/S (branch) China 100% ALK (Shanghai) Medical Technology Co., Ltd. China 100% ALK (Shanghai) Medical Technology Co., Ltd. Beijing (branch) China 100% ALK (Shanghai) Medical Technology Co., Ltd. Guangzhou (branch) China 100% ALK (Guangzhou) Medical Technology Co., Ltd. China 100% Tasfiye Halinde ALK Ilac ve Alerji Ürünleri Ticaret Anonim Sirketi Turkey 100%(In liquidation)
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Annual Report 2025Consolidated financial statements 124
Definitions
Term DefinitionsGross margin – % Gross profit x 100 / RevenueEBIT margin – % EBIT x 100 / RevenueReturn on equity (ROE) – % Net profit/(loss) for the period x 100 / Average equity ROIC incl. goodwill – % Operating profit x 100 / Average invested capital incl. goodwillPay-out ratio – % Proposed dividend x 100 / Net profit/(loss) for the yearEarnings/(loss) per share Net profit/(loss) for the period / Average number of (EPS)outstanding sharesEarnings/(loss) per share Net profit/(loss) for the period / Average number of diluted (DEPS)outstanding shares dilutedCash flow per share (CFPS) Cash flow from operating activities / Average number of outstanding sharesPrice earnings ratio (PE) Share price / Earnings per shareNet asset value per share Net asset value / Number of shares end of periodInvested capital Intangible assets, tangible assets, inventories and current receivables reduced by liabilities except for mortgage debt and bank loansInterest-bearing debt Debt on which interest is paid, including bank debt, debt to credit institutions and lease debtNet interest-bearing debt Interest-bearing debt, less cash, and cash equivalents(NIBD)Markets Geographical markets (based on customer location): Europe comprises the EU, UK, Norway and Switzerland North America comprises the USA and Canada International markets comprise Japan, China and all other countries
The definitions are aligned with generally accepted financial ratios applied by financial analysts.
The definitions are part of the Management’s review.
Alternative Performance MeasuresAmounts in DKKm 2025 2024EBITDA reconciliation to net profitNet profit 1,197 815Tax on profit 438 242Financial income (28) (61)Financial expenses 47 95Depreciation, amortisation and impairment 328 272EBITDA 1,982 1,363Net asset valueEquity 6,445 5,373Net asset value 6,445 5,373Invested capital reconciliationIntangible assets 1,765 1,792Tangible assets 2,264 2,347Inventories 1,783 1,716Trade receivables 1,093 812Income tax receivables 126 10Other receivables 120 49Prepayments 132 118Pensions and similar liabilities (244) (251)Lease liabilities (non-current) (204) (285)Deferred income (non-current) (277) (45)Provisions (non-current) (1) (1)Trade payables (140) (165)Lease liabilities (current) (46) (46)Deferred income (current) (11) (4)Provisions (current) (20) (38)Income tax payables (current) (39) (124)Other payables (1,056) (882)Invested capital 5,245 5,003
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Annual Report 2025Consolidated financial statements 125
127 Income statement
128 Balance sheet
129 Statement of changes in equity
130 Notes
1 Accounting policies 130
2 Revenue and segment information 131
3 Staff costs 131
4 Financial income and expenses 131
5 Income tax 131
6 Intangible assets 132
7 Property, plant and equipment 133
8 Deferred tax 134
9 Investments in subsidiaries 135
10 Inventories 135
11 Mortgage debt and bank loans 135
12 Pensions and similar liabilities 135
13 Lease liabilities 136
14 Contingent liabilities and commitments 136
15 Related parties 136
16 Fees to ALK-Abelló A/S’ auditors 136
17 Proposed appropriation of net profit 136
18 Events after the reporting period 136
NotesContents
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Consolidated Consolidated
financial financial
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Parent company Parent company
financial financial
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Income statementIncome statement
Balance sheetBalance sheet
Statement of changes Statement of changes
in equityin equity
NotesNotes
StatementsStatements
Other Other
informationinformation
Annual Report 2025 126Parent company financial statements
Parent company financial statements
Income statement for the Parent company
Amounts in DKKm Note 2025 2024
Revenue
2 4,057 4,114
Cost of sales
3 2,594 1,457
Gross profit 1,463 2,657
Research and development expenses
3 614 514
Sales and marketing expenses
3 433 466
Administrative expenses
3 270 185
Other operating items, net. (52) -
Operating profit/(loss) (EBIT) 94 1,492
Income from investments in subsidiaries
9 187 119
Financial income
4 47 86
Financial expenses
4 46 69
Profit before tax (EBT) 282 1,628
Tax on profit/(loss)
5 32 325
Net profit
17 250 1,303
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Annual Report 2025 127Parent company financial statements
Balance sheet
Balance sheet for the Parent company – Assets Balance sheet the Parent company – Equity and liabilities
Amounts in DKKm Note
31 Dec.
2025
31 Dec.
2024
Non-current assets
Intangible assets
Goodwill
6 - -
Patents, trademarks and rights
6 986 -
development costs
6 81 65
Software
6 105 91
Intangible assets
6 39 1,044
1,211 1,200
Tangible assets
Land and buildings
7 336 366
Plant and machinery
7 373 286
Other fixtures and equipment
7 52 52
Property, plant and equipment in progress
7 297 329
1,058 1,033
Other non-current assets
Investments in subsidiaries
9 1,058 1,058
Receivables from group companies 963 2,450
Prepayments and securities 43 19
Deferred tax assets
8 - 22
Income tax receivables 108 118
2,172 3,667
Total non-current assets 4,441 5,900
Current assets
Inventories
10 1,258 727
Trade receivables 267 60
Receivables from group companies 473 327
Income tax receivables - 1
Other receivables 46 81
Prepayments 89 88
2,133 1,284
Cash 964 361
Total current assets 3,097 1,645
Total assets 7,53 8 7,545
Amounts in DKKm Note
31 Dec.
2025
31 Dec.
2024
Equity
Share capital 111 111
Retained earnings 4,885 4,969
Capitalised development costs 63 51
Proposed dividend 355 -
Total equity 5,414 5,131
Liabilities
Non-current liabilities
Mortgage debt
11 151 166
Pensions and similar liabilities
12 63 62
Payables to group companies 134 106
Lease liabilities
13 82 131
Deferred income 277 44
Deferred tax liabilities 247 -
954 509
Current liabilities
Mortgage debt
11 17 19
Bank loans
11 - 671
Trade payables 56 72
Payables to group companies 791 885
Lease liabilities
13 15 14
Deferred income 9 3
Other payables 282 241
1,170 1,905
Total liabilities 2,124 2,414
Total equity and liabilities 7, 538 7, 545
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Annual Report 2025 128Parent company financial statements
Statement of changes in equity
Amounts in DKKm
Share
capital
Retained
earnings
Reserve for
capitalised
development
costs
Proposed
dividend
Total
equity
2025
Equity at 1 January 111 4,969 51 - 5,131
Appropriated from net profit - (105) - 355 250
Share-based payments - 45 - - 45
Share options settled - (26) - - (26)
Transfer to/(from) legal reserves - (12) 12 - -
Tax related to items recognised directly in equity - 15 - - 15
Other adjustments - (1) - - (1)
Other transactions - (84) 12 355 283
Equity at 31 December 111 4,885 63 355 5,414
2024
Equity at 1 January 111 3,652 38 - 3,801
Appropriated from net profit - 1,303 - - 1,303
Share-based payments - 51 - - 51
Share options settled - (38) - - (38)
Sale of treasury shares - 6 - - 6
Transfer to legal reserves - (13) 13 - -
Tax related to items recognised directly in equity - 8 - - 8
Other transactions - 1,317 13 - 1,330
Equity at 31 December 111 4,969 51 - 5,131
See note 4.1 in the consolidated financial statements for information on treasury shares.
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Annual Report 2025 129Parent company financial statements
Notes
1 Accounting policies
General
The financial statements of the parent company
ALK-Abelló A/S for the period 1 January to 31
December 2025 have been prepared in accord-
ance with the Danish Financial Statements Act for
large reporting class D enterprises.
The financial statements are presented in Danish
kroner (DKK).
The accounting policies are unchanged from last
year.
The parent company’s accounting policies for
recognition and measurement are in accordance
with the ALK Group’s accounting policies with the
following exceptions:
Income statement
Income from investments in subsidiaries
Dividends from investments in subsidiaries are
recognised in the parent company’s financial
statements when the right to the dividend finally
vests, typically at the date of the company’s
approval in general meeting of the dividend of the
company in question less any write-downs at the
investments.
Balance sheet
Acquisition of activities from subsidiaries
Acquisition of activities from subsidiaries is
accounted for using the purchase method. On
initial recognition, goodwill is measured and
recognised as the excess of the consideration
transferred exceeding the fair value of the net
assets acquired at the acquisition date.
Goodwill
Goodwill is measured at cost less accumulated
amortisation and impairment. Amortisation is
calculated using the straight-line method over the
expected useful life, estimated at 10 years. This
estimate was made based on estimated useful
lives of the assets acquired.
Investments in subsidiaries
Investments in subsidiaries are measured at cost.
Where the recoverable amount of the investments
is lower than cost, the investments are written
down to this lower value.
In addition, cost is written down to the extent that
dividends distributed exceed the accumulated
earnings in the company since the acquisition
date. In the event of indications of impairment, an
impairment test is performed of investments in
subsidiaries.
Capitalisation of development costs
A reserve for capitalisation of development costs
less deferred tax is recognised in the statement of
equity. The reserve contains development costs,
less amortisation/impairment losses, and less
deferred tax, capitalised since 1 January 2016.
Leasing liabilities
Leases are recognised and measured based on
IFRS 16 Leases to align with the accounting poli-
cies for the Group, as permitted under the Danish
Financial Statements Act.
Leases are recognised in the balance sheet as
right-of-use assets and corresponding lease
liabilities, measured at the present value of future
lease payments. Right-of-use assets are depre-
ciated over the lease term, and lease liabilities
are subsequently measured using the effective
interest method, with interest expense recognised
in the income statement.
Short-term leases and leases of low-value assets
are expensed on a straight-line basis over the
lease term.
Other accounting information
Cash flow statement
As allowed under section 86 (4) of the Danish
Financial Statements Act, no cash flow statement
is presented, as this is included in the consoli-
dated cash flow statement.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 130Parent company financial statements
Notes
2 Revenue information
Amounts in DKKm 2025 2024
Sale of goods 3,957 4,003
Royalties 96 108
Services 4 3
Total revenue 4,057 4,114
Europe 3,338 3,579
International markets 719 535
Total revenue 4,057 4,114
3 Staff costs
Amounts in DKKm 2025 2024
Wages and salaries 784 742
Pensions 73 71
Other social security costs, etc. 15 18
Share-based payments 31 33
Total 903 864
Staff costs are allocated as follows:
Cost of sales 348 344
Research and development expenses 286 283
Sales and marketing expenses 78 65
Administrative expenses 148 126
Included in the cost of assets 43 46
Total 903 864
Remuneration to Board of Management and Board of Directors:
See note 2.4 and 5.1 in the consolidated financial statements
Employees
Average number (FTE) 909 923
Number year end (FTE) 921 896
4 Financial income and expenses
Amounts in DKKm 2025 2024
Interest on receivables from group companies 19 18
Other interest income
1
28 68
Total financial income 47 86
Interest on payables to group companies 4 2
Other interest expenses
2
26 40
Currency loss, net 16 27
Total financial expenses 46 69
1
In 2025, other interest income include interest related to uncertain tax positions of DKK 4 million (2024: DKK 4 million)
2
In 2025, other interest expenses include leasing interest expenses of DKK 4 million (2024: DKK 4 million).
5 Income tax
Amounts in DKKm 2025 2024
Current income tax 56 52
Adjustment of deferred tax (5) 273
Prior years adjustments, net (19) -
Total 32 325
Profit before tax 282 1,628
Income tax, tax rate of 22% 62 358
Permanent differences (49) (42)
Prior years adjustments, net (19) -
Other taxes and adjustments 38 9
Tax on profit for the year 32 325
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 131Parent company financial statements
Notes
6 Intangible assets
Amounts in DKKm Goodwill
Patents,
trademarks
and rights
Development
cost
1
Software
Assets in
progress 2025 2024
Cost beginning of year 867 57 77 382 1,044 2,427 1,405
Additions - 32 17 10 24 83 1,043
Disposals - - - (4) - (4) (21)
Transfer to/from other groups - 994 - 35 (1,029) - -
Cost year end 867 1,083 94 423 39 2,506 2,427
Amortisation and impairment beginning of year 867 57 12 291 - 1,227 1,218
Amortisation for the year - 40 1 31 - 72 29
Disposals during the year - - - (4) - (4) (21)
Impairment during the year - - - - - - 1
Amortisation and impairment year end 867 97 13 318 - 1,295 1,227
Carrying amount year end - 986 81 105 39 1,211 1,200
1
The capitalised development cost relates to development of medical device products where the individual minor development projects are running for short-term periods and are subject to limited risk. The development projects are generating economic benefits in
the form of sale of goods. At 31 December 2025, the capitalised development cost relates to the development of the adrenaline auto-injectors for the European and US markets.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 132Parent company financial statements
Notes
7 Property, plant and equipment
Amounts in DKKm
Land and
buildings
Plant and
machinery
Other fixtures
and equipment
Property, plant
and equipment
in progress 2025 2024
Cost beginning of year 730 626 93 329 1,778 1,697
Additions 5 33 11 116 165 121
Remeasurement of lease obligations (34) - - - (34) 4
Disposals (2) (1) (8) (7) (18) (44)
Transfer to/from other groups 35 104 2 (141) - -
Cost year end 734 762 98 297 1,891 1,778
Depreciation and impairment beginning of year 364 340 41 - 745 701
Depreciation for the year 36 50 13 - 99 87
Disposals during the year (2) (1) (8) (7) (18) (44)
Impairment during the year - - - 7 7 1
Depreciation and impairment year end 398 389 46 - 833 745
Carrying amount year end 336 373 52 297 1,058 1,033
of which assets held under leases
1
86 - - - 86 136
Value of land and buildings subject to mortgages 245 228
1
Land and buildings in Denmark include buildings on land leased from Scion DTU A/S, Hørsholm. The estimated lease terms are 8 years.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 133Parent company financial statements
Notes
8 Deferred tax
Amounts in DKKm
Intangible
assets
Tangible
assets
Current and
other assets Liabilities
Tax losses
carried forward Total
2025
Carrying amount beginning of year (239) (83) (1) 44 301 22
Adjustment to prior years - 1 - - (2) (1)
Adjustment of receivables from group companies - - - - (288) (288)
Recognised in the income statement, net 12 5 (40) 42 (14) 5
Recognised in equity, net (share-based payments) - - 12 - 3 15
Carrying amount year end (227) (77) (29) 86 - (247)
2024
Carrying amount beginning of year (19) (73) (31) 44 368 289
Adjustment to prior years (1) (4) 1 1 - (3)
Adjustment of receivables from group companies - - - - 1 1
Recognised in the income statement, net (219) (6) 26 (1) (73) (273)
Recognised in equity, net (share-based payments) - - 3 - 5 8
Carrying amount year end (239) (83) (1) 44 301 22
ALK-Abelló A/S is included in a joint Danish taxation scheme with the Lundbeck Foundation (Lundbeckfond Invest A/S) and its Danish subsidiaries.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 134Parent company financial statements
Notes
9 Investments in subsidiaries
Amounts in DKKm 2025 2024
Cost beginning of year 1,470 1,470
Cost year end 1,470 1,470
Write-down beginning of year 412 412
Write-down year end 412 412
Carrying amount year end 1,058 1,058
In the income statement, income from investments in subsidiaries is dividends, which amounts to DKK 187
million (2024: DKK 119 million).
For an overview of all subsidiaries see note 5.7 in the consolidated financial statements.
10 Inventories
Amounts in DKKm 2025 2024
Raw materials 201 194
Work in progress 518 452
Manufactured goods and goods for resale 539 81
Total 1,258 727
Amount of write-down of inventories during the year 36 10
Amount of reversal of write-down of inventories during the year 13 7
11 Mortgage debt and bank loans
Amounts in DKKm 2025 2024
Debt to mortgage credit institutions secured by buildings
Mortgage debt is due as follows:
Within 1 year 17 19
From 1-5 years 71 74
After 5 years 80 92
Total 168 185
Bank loans
Bank loans are due as follows:
Within 1 year - 671
From 1-5 years - -
After 5 years - -
Total - 671
12 Pensions and similar liabilities
Amounts in DKKm 2025 2024
Pensions and similar liabilities expire as follows:
1
Within 1 year 1 -
From 1-5 years 4 5
After 5 years 59 57
Total 64 62
1
Pensions and similiar liabilities relate to the provision for transition period for the Danish Holiday Act.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 135Parent company financial statements
Notes
13 Lease liabilities
Amounts in DKKm 2025 2024
Lease liabilities expire as follows:
Within 1 year 15 14
From 1-5 years 51 62
After 5 years 31 69
Total 97 145
14 Contingent liabilities and commitments
For information on contingent liabilities and commitments, see note 3.10 in the consolidated financial
statements.
15 Related parties
ALK-Abelló A/S is included in the consolidated financial statements of the Lundbeck Foundation (Lund-
beckfond Invest A/S, incorporated in Denmark).
ALK-Abelló A/S has had transactions with subsidiaries during 2025. All subsidiaries are owned 100%. The
transactions are eliminated in the consolidated financial statements.
Transactions with the majority shareholder are disclosed in note 5.4 in the consolidated financial state-
ments. Apart from remuneration, no other transactions have taken place during the year with Board of
Directors, Board of Management, major shareholders or other related parties.
With reference to section 98c (6) of the Danish Financial Statements Act, the company has chosen only to
disclose transactions with related parties not carried through on normal market items.
Remuneration, etc. to Board of Directors and Board of Management
For information on remuneration and exercise of share options for the ALK Group’s Board of Directors and
Board of Management, see note 2.4 and 5.1 in the consolidated financial statements.
16 Fees to ALK-Abelló A/S’ auditors
Amounts in DKKm 2025 2024
Fees to the auditors appointed at the annual general meeting:
Audit services 2 2
Other opinions 2 2
Tax advisory services 1 1
Other services - -
Total 5 5
17 Proposed appropriation of net profit
Amounts in DKKm 2025 2024
Proposed dividend 355 -
Retained earnings (105) 1,303
Net profit 250 1,303
18 Events after the reporting period
No events have occured after the reporting period, that influence the evaluation of the parent company
financial statements.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Income statement
Balance sheet
Statement of
changes in equity
Notes
Statements
Other
information
Annual Report 2025 136Parent company financial statements
Statement by Management on the annual report
The Board of Directors and the Board of Manage-
ment have today considered and adopted the
annual report of ALK-Abelló A/S for the financial
year 1 January to 31 December 2025.
The consolidated financial statements have been
prepared in accordance with IFRS accounting
standards as adopted by the EU and further
requirements in the Danish Financial Statements
Act. The parent company financial statements
have been prepared in accordance with the
Danish Financial Statements Act. Management's
review has been prepared in accordance with the
Danish Financial Statements Act.
In our opinion, the consolidated financial state-
ments and the parent company financial state-
ments give a true and fair view of the financial
position at 31 December 2025 of the group and
the parent company and of the results of the
group and parent company operations and
consolidated cash flows for the financial year 1
January to 31 December 2025.
In our opinion, Management’s review includes a
true and fair account of the development in the
operations and financial circumstances of the
group and the parent company, of the results for
the year, and of the financial position of the group
and the parent company, as well as a descrip-
tion of the most significant risks and elements
of uncertainty which the group and the parent
company are facing.
Additionally, the Sustainability Statement,
which is part of Management’s review, has been
prepared, in all material respects, in accordance
with paragraph 99 a of the Danish Financial
Statements Act. This includes compliance with
the European Sustainability Reporting Standards
(ESRS) including that the process undertaken by
Management to identify the reported information
(the “Process”) is in accordance with the descrip-
tion set out in section “Description of the process
to identify and assess material impacts, risks
and opportunities”. Furthermore, disclosures in
subsection “EU Taxonomy” in the environmental
section of the Sustainability Statement are, in all
material respects, in accordance with Article 8 of
EU Regulation 2020/852 (the “Taxonomy Regula-
tion).
The sustainability statement includes forward-
looking statements based on disclosed assump-
tions about events that may occur in the future
and possible future actions by the Group.
Actual outcomes are likely to be different since
anticipated events frequently do not occur as
expected.
In our opinion, the annual report of ALK-Abelló A/S
for the financial year 1 January to 31 December
2025 with the file name alk-2025-12-31-en.zip is
prepared, in all material respects, in compliance
with the ESEF Regulation.
We recommend that the annual report be
adopted at the annual general meeting.
rsholm, 20 February 2026
Board of Management
Peter Halling Claus Steensen Sølje
President & CEO Executive Vice President
& CFO
Henriette Mersebach
Executive Vice President,
Research & Development
Board of Directors
Anders Hedegaard Lene Skole
Chair Vice Chair
Gitte Aabo Lars Holmqvist Jesper Høiland
Bertil Lindmark Alan Main Katja Barnkob
Nanna Rassov Carlson Lise Lund Mærkedahl Johan Smedsrud
Management's
review
Sustainability
statement
Financial
statements
Consolidated Consolidated
financial financial
statementsstatements
Parent company Parent company
financial financial
statementsstatements
StatementsStatements
Statement by Statement by
Management on Management on
the annual reportthe annual report
Independent Independent
Auditor’s ReportsAuditor’s Reports
Independent Independent
auditor’s limited auditor’s limited
assurance report on assurance report on
the Sustainability the Sustainability
StatementStatement
Other Other
informationinformation
Annual Report 2025Statement by Management on the annual report 137
Statements
Independent Auditor’s Reports
To the shareholders of ALK-Abelló A/S
Report on the audit of
the Financial Statements
Our opinion
In our opinion, the Consolidated Financial State-
ments give a true and fair view of the Group’s
financial position at 31 December 2025 and of the
results of the Group’s operations and cash flows
for the financial year 1 January to 31 December
2025 in accordance with IFRS Accounting Stand-
ards as adopted by the EU and further require-
ments in the Danish Financial Statements Act.
Moreover, in our opinion, the Parent Company
Financial Statements give a true and fair view
of the Parent Company’s financial position at 31
December 2025 and of the results of the Parent
Company’s operations for the financial year 1
January to 31 December 2025 in accordance with
the Danish Financial Statements Act.
Our opinion is consistent with our Auditor’s Long-
form Report to the Audit Committee and the Board
of Directors.
What we have audited
The Consolidated Financial Statements (pp 85-125)
and Parent Company Financial Statements (pp
126-136) of ALK-Abelló A/S for the financial year 1
January to 31 December 2025 comprise income
statement, balance sheet, statement of changes
in equity and notes, including material accounting
policy information for the Group as well as for the
Parent Company, and statement of comprehensive
income and cash flow statement for the Group.
Collectively referred to as the “Financial State-
ments”.
Basis for opinion
We conducted our audit in accordance with Inter-
national Standards on Auditing (ISAs) and the
additional requirements applicable in Denmark.
Our responsibilities under those standards and
requirements are further described in the Audi-
tor’s responsibilities for the audit of the Financial
Statements section of our report.
We believe that the audit evidence we have
obtained is sufficient and appropriate to provide
a basis for our opinion.
Independence
We are independent of the Group in accordance
with the International Ethics Standards Board
for Accountants’ International Code of Ethics
for Professional Accountants (IESBA Code) as
applicable to audits of financial statements of
public interest entities, and the additional ethical
requirements applicable in Denmark. We have also
fulfilled our other ethical responsibilities in accord-
ance with these requirements and the IESBA Code.
To the best of our knowledge and belief, prohibited
non-audit services referred to in Article 5(1) of
Regulation (EU) No 537/2014 were not provided.
Appointment
We were first appointed auditors of ALK-Abel
A/S on 11 March 2020 for the financial year 2020.
We have been reappointed annually by share-
holder resolution for a total period of uninterrupted
engagement of 6 years including the financial year
2025.
Key audit matters
Key audit matters are those matters that, in our professional judgement, were of most signifi-
cance in our audit of the Financial Statements for 2025. These matters were addressed in the
context of our audit of the Financial Statements as a whole, and in forming our opinion thereon,
and we do not provide a separate opinion on these matters.
Key audit matter
How our audit addressed
the key audit matter
Revenue recognition
The Group sells products through different
sales channels in various markets and part-
nership agreements. The different sales
channels and markets are subject to various
rebate and discount agreements as well
as mandated price adjustments schemes.
The partnership agreements are complex
in nature, as they include multiple elements
and performance obligations.
We focused on these areas as accounting
for rebates, discounts, mandated price
adjustments, and partnership agreements
is complex and requires a high degree of
estimation and judgement by Management.
This includes the estimation uncertainty
regarding accruals for estimated sales
deductions and judgements and estimates
regarding recognition of revenue from part-
nership agreements.
We refer to note 2.1 in the consolidated
financial statements.
We discussed the policies for revenue recog-
nition, including accounting for rebates,
discounts and mandated price adjustments
with Management.
We performed risk assessment procedures
to obtain an understanding of the IT systems,
business processes and relevant controls for
revenue recognition and related sales deduc-
tions. We assessed whether the controls were
designed and implemented to effectively
address the risk of material misstatement, and
tested these, where relevant.
We evaluated and challenged the assumptions
and estimates, including methods, data and
assumptions used for calculating rebates,
discounts, mandated price adjustments and
accruals for sales deductions.
We read partnership agreements, evaluated
and challenged the judgements and estimates
made regarding recognition of revenue relating
to these agreements.
We assessed the appropriateness of the
related disclosure provided in the consolidated
financial statements.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Statements
Statement by
Management on
the annual report
Independent
Auditor’s Reports
Independent
auditor’s limited
assurance report on
the Sustainability
Statement
Other
information
Annual Report 2025 138Independent Auditor’s Reports
Statement on Management’s Review
Management is responsible for Management’s
Review (pp 1-84 and 143).
Our opinion on the Financial Statements does not
cover Management’s Review, and we do not as
part of the audit express any form of assurance
conclusion thereon.
In connection with our audit of the Financial
Statements, our responsibility is to read Manage-
ment’s Review and, in doing so, consider whether
Management’s Review is materially inconsistent
with the Financial Statements or our knowledge
obtained in the audit, or otherwise appears to be
materially misstated.
Moreover, we considered whether Management’s
Review includes the disclosures required by
the Danish Financial Statements Act. This does
not include the requirements in paragraph 99 a
related to the Sustainability Statement covered by
the separate auditor’s limited assurance report
hereon.
Based on the work we have performed, in our
view, Managements Review is in accordance with
the Consolidated Financial Statements and the
Parent Company Financial Statements and has
been prepared in accordance with the require-
ments of the Danish Financial Statements Act,
except for the requirements in paragraph 99 a
related to the Sustainability Statement, cf. above.
We did not identify any material misstatement in
Management’s Review.
Management’s responsibilities for
the Financial Statements
Management is responsible for the preparation of
consolidated financial statements that give a true
and fair view in accordance with IFRS Accounting
Standards as adopted by the EU and further
requirements in the Danish Financial Statements
Act and for the preparation of parent company
financial statements that give a true and fair
view in accordance with the Danish Financial
Statements Act, and for such internal control as
Management determines is necessary to enable
the preparation of financial statements that are
free from material misstatement, whether due to
fraud or error.
In preparing the Financial Statements, Manage-
ment is responsible for assessing the Group’s
and the Parent Company’s ability to continue as a
going concern, disclosing, as applicable, matters
related to going concern and using the going
concern basis of accounting unless Management
either intends to liquidate the Group or the Parent
Company or to cease operations, or has no real-
istic alternative but to do so.
Auditor’s responsibilities for the audit of
the Financial Statements
Our objectives are to obtain reasonable assur-
ance about whether the Financial Statements
as a whole are free from material misstatement,
whether due to fraud or error, and to issue
an auditor’s report that includes our opinion.
Reasonable assurance is a high level of assur-
ance, but is not a guarantee that an audit
conducted in accordance with ISAs and the
additional requirements applicable in Denmark
will always detect a material misstatement when
it exists. Misstatements can arise from fraud or
error and are considered material if, individually
or in the aggregate, they could reasonably be
expected to influence the economic decisions of
users taken on the basis of these Financial State-
ments.
As part of an audit in accordance with ISAs
and the additional requirements applicable in
Denmark, we exercise professional judgement
and maintain professional scepticism throughout
the audit. We also:
Identify and assess the risks of material
misstatement of the Financial Statements,
whether due to fraud or error, design and
perform audit procedures responsive to those
risks, and obtain audit evidence that is suffi-
cient and appropriate to provide a basis for
our opinion. The risk of not detecting a material
misstatement resulting from fraud is higher
than for one resulting from error, as fraud may
involve collusion, forgery, intentional omissions,
misrepresentations, or the override of internal
control.
Obtain an understanding of internal control
relevant to the audit in order to design audit
procedures that are appropriate in the circum-
stances, but not for the purpose of expressing
an opinion on the effectiveness of the Group’s
and the Parent Company’s internal control.
Evaluate the appropriateness of accounting
policies used and the reasonableness of
accounting estimates and related disclosures
made by Management.
Conclude on the appropriateness of Manage-
ment’s use of the going concern basis of
accounting and based on the audit evidence
obtained, whether a material uncertainty
exists related to events or conditions that may
cast significant doubt on the Group’s and the
Parent Company’s ability to continue as a
going concern. If we conclude that a material
uncertainty exists, we are required to draw
attention in our auditor’s report to the related
disclosures in the Financial Statements or, if
such disclosures are inadequate, to modify
our opinion. Our conclusions are based on the
audit evidence obtained up to the date of our
auditor’s report. However, future events or
conditions may cause the Group or the Parent
Company to cease to continue as a going
concern.
Evaluate the overall presentation, structure
and content of the Financial Statements,
including the disclosures, and whether the
Financial Statements represent the underlying
transactions and events in a manner that gives
a true and fair view.
Plan and perform the group audit to obtain
sufficient appropriate audit evidence regarding
the financial information of the entities or
business units within the group as a basis for
forming an opinion on the Consolidated Finan-
cial Statements. We are responsible for the
direction, supervision and review of the audit
work performed for purposes of the group
audit. We remain solely responsible for our
audit opinion.
We communicate with those charged with
governance regarding, among other matters,
the planned scope and timing of the audit and
significant audit findings, including any significant
deficiencies in internal control that we identify
during our audit.
We also provide those charged with governance
with a statement that we have complied with rele-
vant ethical requirements regarding independ-
ence, and to communicate with them all relation-
ships and other matters that may reasonably be
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Statements
Statement by
Management on
the annual report
Independent
Auditor’s Reports
Independent
auditor’s limited
assurance report on
the Sustainability
Statement
Other
information
Annual Report 2025 139Independent Auditor’s Reports
thought to bear on our independence and, where
applicable, actions taken to eliminate threats or
safeguards applied.
From the matters communicated with those
charged with governance, we determine those
matters that were of most significance in the
audit of the Financial Statements of the current
period and are therefore the key audit matters.
We describe these matters in our auditor’s report
unless law or regulation precludes public disclo-
sure about the matter.
Report on compliance with
the ESEF Regulation
As part of our audit of the Financial Statements
we performed procedures to express an opinion
on whether the annual report of ALK-Abelló A/S
for the financial year 1 January to 31 December
2025 with the filename alk-2025-12-31-en.zip is
prepared, in all material respects, in compliance
with the Commission Delegated Regulation (EU)
2019/815 on the European Single Electronic
Format (ESEF Regulation) which includes require-
ments related to the preparation of the annual
report in XHTML format and iXBRL tagging of the
Consolidated Financial Statements including
notes.
Management is responsible for preparing an
annual report that complies with the ESEF Regula-
tion. This responsibility includes:
Preparing of the annual report in XHTML format;
Selection and application of appropriate
iXBRL tags, including extensions to the ESEF
taxonomy and the anchoring thereof to
elements in the taxonomy, for all financial infor-
mation required to be tagged using judgement
where necessary;
Ensuring consistency between iXBRL tagged
data and the Consolidated Financial State-
ments presented in human-readable format;
and
For such internal control as Management deter-
mines necessary to enable the preparation of
an annual report that is compliant with the ESEF
Regulation.
Our responsibility is to obtain reasonable assur-
ance on whether the annual report is prepared,
in all material respects, in compliance with the
ESEF Regulation based on the evidence we have
obtained, and to issue a report that includes
our opinion. The nature, timing and extent of
procedures selected depend on the auditor’s
judgement, including the assessment of the risks
of material departures from the requirements set
out in the ESEF Regulation, whether due to fraud
or error. The procedures include:
Testing whether the annual report is prepared
in XHTML format;
Obtaining an understanding of the company’s
iXBRL tagging process and of internal control
over the tagging process;
Evaluating the completeness of the iXBRL
tagging of the Consolidated Financial State-
ments including notes;
Evaluating the appropriateness of the compa-
ny’s use of iXBRL elements selected from the
ESEF taxonomy and the creation of extension
elements where no suitable element in the ESEF
taxonomy has been identified;
Evaluating the use of anchoring of extension
elements to elements in the ESEF taxonomy;
and
Reconciling the iXBRL tagged data with the
audited Consolidated Financial Statements.
In our opinion, the annual report of ALK-Abelló A/S
for the financial year 1 January to 31 December
2025 with the file name alk-2025-12-31-en.zip is
prepared, in all material respects, in compliance
with the ESEF Regulation.
Hellerup, 20 February 2026
PricewaterhouseCoopers
Statsautoriseret Revisionspartnerselskab
CVR No 33 77 12 31
Lars Baungaard
State Authorised Public Accountant
mne23331
Kim Tromholt
State Authorised Public Accountant
mne33251
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Statements
Statement by
Management on
the annual report
Independent
Auditor’s Reports
Independent
auditor’s limited
assurance report on
the Sustainability
Statement
Other
information
Annual Report 2025 140Independent Auditor’s Reports
Independent auditor’s limited assurance report on
the Sustainability Statement
To the stakeholders of ALK-Abelló A/S
Limited assurance conclusion
We have conducted a limited assurance
engagement on the sustainability statement of
ALK-Abelló A/S (the “Group”) included in Manage-
ment’s Review, page 37 – 84, for the financial year
1 January – 31 December 2025 (the “Sustaina-
bility Statement”).
Based on the procedures we have performed
and the evidence we have obtained, nothing has
come to our attention that causes us to believe
that the Sustainability Statement is not prepared,
in all material respects, in accordance with the
Danish Financial Statements Act paragraph 99 a,
including:
compliance with the European Sustainability
Reporting Standards (ESRS), including that the
process carried out by Management to identify
the information reported in the Sustainability
Statement (the “Process”) is in accordance with
the description set out in the section “Descrip-
tion of the process to identify and assess mate-
rial impacts, risks and opportunities”; and
compliance of the disclosures in the section
“EU Taxonomy” of the Sustainability Statement
with Article 8 of EU Regulation 2020/852 (the
“Taxonomy Regulation”).
Basis for conclusion
We conducted our limited assurance engagement
in accordance with International Standard on
Assurance Engagements (ISAE) 3000 (Revised),
Assurance engagements other than audits or
reviews of historical financial information
(“ISAE
3000 (Revised)”) and the additional requirements
applicable in Denmark.
The procedures in a limited assurance engage-
ment vary in nature and timing from, and are
less in extent than for, a reasonable assurance
engagement. Consequently, the level of assur-
ance obtained in a limited assurance engagement
is substantially lower than the assurance that
would have been obtained had a reasonable
assurance engagement been performed.
We believe that the evidence we have obtained
is sufficient and appropriate to provide a basis
for our conclusion. Our responsibilities under this
standard are further described in the Auditors
responsibilities for the assurance engagement
section of our report.
Our independence and quality management
We are independent of the Group in accordance
with the International Ethics Standards Board
for Accountants’ International Code of Ethics for
Professional Accountants (IESBA Code) and the
additional ethical requirements applicable in
Denmark. We have also fulfilled our other ethical
responsibilities in accordance with these require-
ments and the IESBA Code.
Our firm applies International Standard on Quality
Management 1, which requires the firm to design,
implement and operate a system of quality
management including policies or procedures
regarding compliance with ethical requirements,
professional standards and applicable legal and
regulatory requirements.
Other matter
The comparative information for the years 2022
and 2023 included in the Sustainability Statement
was not subject to an assurance engagement.
Our conclusion is not modified in respect of this
limitation of scope.
Management’s responsibilities for the
Sustainability Statement
Management is responsible for designing and
implementing a process to identify the informa-
tion reported in the Sustainability Statement in
accordance with ESRS and for disclosing this
Process as included in the section “Description
of the process to identify and assess material
impacts, risks and opportunities” of the Sustaina-
bility Statement. This responsibility includes:
understanding the context in which the Group’s
activities and business relationships take
place and developing an understanding of its
affected stakeholders;
identification of the actual and potential
impacts (both negative and positive) related
to sustainability matters, as well as risks and
opportunities that affect, or could reasonably
be expected to affect, the Group’s financial
position, financial performance, cash flows,
access to finance or cost of capital over the
short-, medium-, or long-term;
assessment of the materiality of the identi-
fied impacts, risks and opportunities related
to sustainability matters by selecting and
applying appropriate thresholds; and
making assumptions that are reasonable in the
circumstances.
Management is further responsible for the prepa-
ration of the Sustainability Statement, which
includes the information identified by the Process,
in accordance with the Danish Financial State-
ments Act paragraph 99 a, including:
compliance with the ESRS;
preparing the disclosures as included in the
section “EU Taxonomy” of the Sustainability
Statement, in compliance with Article 8 of the
Taxonomy Regulation;
designing, implementing and maintaining such
internal control that Management determines
is necessary to enable the preparation of
the Sustainability Statement that is free from
material misstatement, whether due to fraud or
error; and
selection and application of appropriate
sustainability reporting methods and making
assumptions and estimates that are reason-
able in the circumstances.
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Statements
Statement by
Management on
the annual report
Independent
Auditor’s Reports
Independent
auditor’s limited
assurance report on
the Sustainability
Statement
Other
information
Annual Report 2025 141Independent auditor’s limited assurance report on the Sustainability Statement
Inherent limitations in preparing the Sustaina-
bility Statement
In reporting forward-looking information in
accordance with ESRS, Management is required
to prepare forward-looking information on the
basis of disclosed assumptions about events
that may occur in the future and possible future
actions by the Group. Actual outcomes are likely
to be different since anticipated events frequently
do not occur as expected.
Auditor’s responsibilities for the assurance
engagement
Our responsibility is to plan and perform the
assurance engagement to obtain limited assur-
ance about whether the Sustainability Statement
is free from material misstatement, whether
due to fraud or error, and to issue a limited
assurance report that includes our conclusion.
Misstatements can arise from fraud or error and
are considered material if, individually or in the
aggregate, they could reasonably be expected to
influence decisions of users taken on the basis of
the Sustainability Statement as a whole.
As part of a limited assurance engagement in
accordance with ISAE 3000 (Revised) we exercise
professional judgement and maintain profes-
sional scepticism throughout the engagement.
Our responsibilities in respect of the Process
include:
Obtaining an understanding of the Process, but
not for the purpose of providing a conclusion on
the effectiveness of the Process, including the
outcome of the Process;
Considering whether the information identified
addresses the applicable disclosure require-
ments of the ESRS; and
Designing and performing procedures to eval-
uate whether the Process is consistent with the
Group’s description of its Process, as disclosed
in the section “Description of the process to
identify and assess material impacts, risks and
opportunities”.
Our other responsibilities in respect of the Sustain-
ability Statement include:
Identifying where material misstatements are
likely to arise, whether due to fraud or error;
and
Designing and performing procedures respon-
sive to disclosures in the Sustainability State-
ment where material misstatements are likely
to arise. The risk of not detecting a material
misstatement resulting from fraud is higher
than for one resulting from error, as fraud may
involve collusion, forgery, intentional omissions,
misrepresentations, or the override of internal
control.
Summary of the work performed
A limited assurance engagement involves
performing procedures to obtain evidence about
the Sustainability Statement. The nature, timing
and extent of procedures selected depend on
professional judgement, including the identifica-
tion of disclosures where material misstatements
are likely to arise, whether due to fraud or error, in
the Sustainability Statement.
In conducting our limited assurance engagement,
with respect to the Process, we:
Obtained an understanding of the Process by
performing inquiries to understand the sources
of the information used by Management; and
reviewing the Groups internal documentation
of its Process; and
Evaluated whether the evidence obtained
from our procedures about the Process imple-
mented by the Group was consistent with the
description of the Process set out in the section
“Description of the process to identify and
assess material impacts, risks and opportuni-
ties”.
In conducting our limited assurance engagement,
with respect to the Sustainability Statement, we:
Obtained an understanding of the Groups
reporting processes relevant to the prepara-
tion of its Sustainability Statement, including
the consolidation processes, by obtaining an
understanding of the Groups control envi-
ronment, processes and information systems
relevant to the preparation of the Sustainability
Statement but not evaluating the design of
particular control activities, obtaining evidence
about their implementation or testing their
operating effectiveness;
Evaluated whether the information identified
by the Process is included in the Sustainability
Statement;
Evaluated whether the structure and the pres-
entation of the Sustainability Statement are in
accordance with the ESRS;
Performed inquiries of relevant personnel and
analytical procedures on selected information
in the Sustainability Statement;
Performed limited substantive assurance
procedures on selected information in the
Sustainability Statement;
Where applicable, compared disclosures in
the Sustainability Statement with the corre-
sponding disclosures in the Financial State-
ments and Management’s Review;
Evaluated the methods, assumptions and data
for developing estimates and forward-looking
information; and
Obtained an understanding of the Groups
process to identify taxonomy-eligible and
taxonomy-aligned economic activities and the
corresponding disclosures in the Sustainability
Statement.
Hellerup, 20 February 2026
PricewaterhouseCoopers
Statsautoriseret Revisionspartnerselskab
CVR No 33 77 12 31
Lars Baungaard
State Authorised Public Accountant
mne23331
Kim Tromholt
State Authorised Public Accountant
mne33251
Management's
review
Sustainability
statement
Financial
statements
Consolidated
financial
statements
Parent company
financial
statements
Statements
Statement by
Management on
the annual report
Independent
Auditor’s Reports
Independent
auditor’s limited
assurance report on
the Sustainability
Statement
Other
information
Annual Report 2025 142Independent auditor’s limited assurance report on the Sustainability Statement
Financial highlights and key ratios by quarter for the ALK Group (unaudited)
Amounts in DKKm 2025
Q4
unaudited
Q3
unaudited
Q2
unaudited
Q1
unaudited
Income statement
Revenue 6,312 1,733 1,530 1,527 1,522
Cost of sales 2,078 553 487 532 506
Research and development expenses 609 189 145 146 129
Sales and marketing expenses 1,584 473 387 385 339
Administrative expenses 388 132 88 89 79
Other operating items, net 1 1 - - -
Operating profit (EBIT) 1,654 387 423 375 469
Net financial items (19) 6 (4) (25) 4
Profit before tax (EBT) 1,635 393 419 350 473
Net profit 1,197 266 314 263 354
EBITDA 1,982 482 510 450 540
Average number of employees (FTE) 2,737 2,748 2,794 2,782 2,736
Revenue
(Growth in revenue in local currency %)
Europe 4,459 (14) 1,296 (14) 1,048 (18) 1,024 (13) 1,091 (10)
– SLIT-tablets 2,485 (19) 739 (20) 557 (23) 570 (17) 619 (17)
– SCIT/SLIT-drops 1,619 (3) 480 (2) 380 (7) 350 (1) 409 (3)
– Anaphylaxis & other products 355 (34) 77 (40) 111 (39) 104 (51) 63 (1)
North America 1,037 (19) 270 (24) 252 (20) 269 (17) 246 (14)
– SLIT-tablets 247 (24) 53 (21) 52 (20) 76 (32) 66 (22)
– SCIT/SLIT-drops 356 (2) 92 (3) 87 (1) 89 (2) 88 (3)
– Anaphylaxis & other products 434 (34) 125 (48) 113 (41) 104 (23) 92 (20)
International markets 816 (16) 167 (36) 230 (14) 234 (1) 185 (24)
– SLIT-tablets 603 (8) 118 (-11) 128 (-4) 185 (9) 172 (41)
– SCIT/SLIT-drops 170 (44) 35 (N/A) 90 (43) 42 (-20) 3 (-85)
– Anaphylaxis & other products 43 (39) 14 (174) 12 (112) 7 (-33) 10 (7)
Total revenue 6,312 (15) 1,733 (17) 1,530 (18) 1,527 (12) 1,522 (12)
– SLIT-tablets 3,335 (17) 910 (15) 737 (17) 831 (16) 857 (22)
– SCIT/SLIT-drops 2,145 (5) 607 (11) 557 (11) 481 (-1) 500 (0)
– Anaphylaxis & other products 832 (34) 216 (50) 236 (42) 215 (30) 165 (11)
Amounts in DKKm 2025
Q4
unaudited
Q3
unaudited
Q2
unaudited
Q1
unaudited
Balance sheet
Total assets 9,057 9,057 8,474 8,272 8,18 8
Invested capital 5,245 5,245 5,075 5,023 5,026
Equity 6,445 6,445 6,173 5,847 5,676
Cash flow and investments
Cash flow from operating activities 1,817 722 386 320 389
Cash flow from investing activities (385) (126) (96) (104) (59)
– of which investment in intangible assets (84) (16) (11) (48) (9)
– of which investment in tangible assets (276) (96) (74) (58) (48)
– of which acquisitions and operations (10) - (10) - -
Free cash flow 1,432 596 290 216 330
Information on shares
Dividend - - - - -
Share capital 111 111 111 111 111
Shares in thousands of DKK 0.50 each 222,824 222,824 222,824 222,824 222,824
Share price, end period – DKK 229 229 208 187 139
Net asset value per share – DKK 29 29 28 26 25
Key figures
Gross margin – % 67 68 68 65 67
EBIT margin - % 26 22 28 25 31
Earnings per share (EPS) – DKK 5.4 1.2 1.4 1.2 1.6
Earnings per share diluted (DEPS) – DKK 5.4 1.2 1.4 1.2 1.6
Cash flow per share (CFPS)– DKK 8.2 3.3 1.7 1.4 1.8
Share price/Net asset value 7.9 7.9 7.5 7.1 5.4
1
Management’s review comprises this page as well as pages 1-84 and Financial highlights and key ratios for the ALK Group on
page 21.
Definitions: see page 125.
1
Management's
review
Sustainability
statement
Financial
statements
Consolidated Consolidated
financial financial
statementsstatements
Parent company Parent company
financial financial
statementsstatements
Other Other
informationinformation
Financial highlights Financial highlights
and key ratios by and key ratios by
quarter for the ALK quarter for the ALK
Group (unaudited)Group (unaudited)
Annual Report 2025Financial highlights and key ratios by quarter for the ALK Group (unaudited) 143
Other information
1
Design and production: Noted
ALK-Abelló A/S
Bøge Allé 6-8
DK-2970 Hørsholm
Denmark
CVR no. 63 71 79 16
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