The second part of the phase I/II trial with the tablet for
peanut allergy – ALK’s most advanced programme
within food allergy – is progressing according to plans.
Next results from the trial are still expected in H2 2024
and ALK has made a provisional decision to extend
the trial with a third part to explore efficacy of the tablet
as well. The development of a new, next-generation
autoinjector (the Genesis project) also progresses as
planned, and further administration forms are being
evaluated to establish a portfolio of solutions for the
treatment of acute life-threatening allergic reactions
(anaphylaxis).
less influenced by pan-European trading patterns at
wholesaler levels than previously.
Combined sales of SCIT/SLIT-drops increased by
15%. SCIT sales progressed well in most Central and
Northern European markets, with growth in both the
venom and non-venom sub-segments. Sales in main
market Germany grew in solid double digits, supported
by competitive dynamics and the market transition
towards evidence-based products. SCIT sales were
also influenced positively by certain price and rebate
adjustments. Sales of SLIT-drops, which are
predominantly marketed in France, exceeded
expectations with growth linked to higher patient flow
to existing and new allergy doctors.
To facilitate the planned growth, efforts also
progressed to expand manufacturing capacity for
tablets to around 800 million units in 2030. Activities
are also on track to establish the supply chain for the
ongoing Genesis autoinjector development project and
strengthen the existing supply chain for the Jext®
autoinjector.
Sales of Other products and services (predominantly
the adrenaline pen Jext®, diagnostics, etc.) increased
by 12%. European Jext® sales grew by 14% as market
supply continued to normalise after last year’s supply
limitations, caused by issues at a contract
manufacturer from Q2 to Q4 2023.
Q2 SALES AND MARKET TRENDS
(Comparative figures for Q2 2023 are shown in brackets.
Revenue growth rates are stated in local currencies, unless
otherwise indicated)
North America
Revenue in North America increased by 3% in local
currencies to DKK 241 million (232).
Revenue by geography
DKKm
Q2
2024
900
241
233
Share of
revenue
65%
Q2
2023
721
232
182
Tablet sales increased by 29% and was positively
influenced by higher realised selling prices in the USA
and volume growth in both the USA and Canada.
Growth*
25%
Europe
North America
Int’l markets
3%
32%
21%
18%
17%
100% 1,135
Sales of bulk allergen extracts (SCIT) to US allergists,
grew by 4% and growth has improved compared to the
previous quarter. Sales of Other products (diagnostics,
PRE-PEN® and life science products) fell short of
expectations with a 9% decrease mainly due to lower
PRE-PEN® sales. The integration of the newly
acquired penicillin diagnostic operation progressed as
planned, but sales continued to be impacted by
stocking at wholesalers prior to ALK’s take-over in
January.
Revenue
1,374
* In local currencies
Revenue in Europe was better than previously
forecasted in the Q1 report and grew by 25% in local
currencies to DKK 900 million (721) on double-digit
growth in all product lines. Particularly sales of tablets
and SLIT-drops exceeded expectations.
Double-digit sales growth was seen in most markets in
Q2 – including the region’s largest markets; Germany,
France, the Nordic countries, and the Benelux
countries – as ALK further progressed its efforts to
activate patients, prescribers, payers, and key opinion
leaders.
International markets
Revenue in International markets increased by 32% in
local currencies to DKK 233 million (182). Growth was
attributable to the timing of product shipments to China
and Japan, the two largest markets in the region.
European tablet sales grew by 35% against a weak
quarter last year. The growth was primarily due to
higher volumes driven by a strong inflow of new
patients particularly in Central and Northern Europe
during the past year, combined with certain price and
rebate adjustments. The reversal of last year’s
Revenue from China, especially from SCIT product
shipments, grew by high double digits. Chinese in-
market sales of SCIT products continued to show
double-digit growth supported by the ongoing
expansion of the prescriber base.
mandatory rebate increase in Germany influenced
growth positively by more than 2 percentage points.
Tablet sales in Germany continued to benefit from the
accelerated market transition towards evidence-based,
registered products, leading to high-double digit sales
growth. ALK also saw a pick-up in the number of
patients initiated on tablets in France. Furthermore,
ALK continued to observe that Q2 tablet sales were
Revenue from Japan (product shipments and sales
royalties) grew by double digits, mirroring continued
growth in Torii’s in-market tablet sales, despite
intermittent capacity limitations at Torii.
Tablet sales also progressed in Southeast Asia and
other, minor international markets.
Page 5 of 17
Company release No 16/2024 – 22 August 2024
ALK-Abelló A/S – Bøge Allé 6-8 – DK-2970 Hørsholm – Denmark – www.alk.net
Tel +45 4574 7576 – CVR No 63 71 79 16 – LEI code: 529900SGCREUZCZ7P020