2025  
Annual Report  
Improving kidney health and patientsquality  
of life through actionable biomarkers, thereby  
transforming kidney care globally  
BioPorto A/S
Tuborg Havnevej 15, ground floor  
DK-2900 Hellerup  
CVR-no: 17500317  
1
BioPorto A/S  
2025 Annual Report  
 
Table of Contents  
Management Commentary  
Shareholder Matters  
Vision and Ambition  
4
5
7
8
9
10  
15  
19  
22  
Investor Relations  
40  
41  
42  
OTHER SUPPLEMENTARY  
REPORTS 2025  
Message from the Chair and the CEO  
Consolidated Financial Highlights  
Financial outlook for 2026  
Aspirations Towards 2028  
Strategy  
Products and Market Position  
Financial Review  
Risk Management  
Shares  
Dividend Policy, Analysts, & Meetings  
Remuneration Report  
Corporate Governance  
Report  
Financial Statements  
Consolidated Financial Statements  
Notes to Consolidated Financial Statements  
Parent Company Financial Statements  
Notes to Parent Company Financial Statements  
44  
48  
77  
80  
FOLLOW US  
Website  
LinkedIn  
X
Governance  
Other Statements & Reports  
Statement by the Board of Directors & Management  
Independent Auditors Report  
Corporate Governance  
27  
28  
86  
87  
Board of Directors & Executive Management  
Corporate Social Responsibility  
UN Global Compact  
Diversity  
35  
37  
2
BioPorto A/S  
2025 Annual Report  
 
Management  
Commentary  
Vision and Ambition  
4
5
Message from the Chair and the CEO  
Consolidated Financial Highlights  
Financial outlook for 2026  
Aspirations Towards 2028  
Strategy  
7
8
9
10  
15  
19  
22  
Products and Market Position  
Financial Review  
Risk Management  
3
BioPorto A/S  
2025 Annual Report  
 
Vision and Ambition  
BioPorto aspires to be a world leader  
in actionable kidney diagnostics  
BioPorto develops actionable biomarker tests designed to give clinicians  
earlier warning of kidney injury in critically ill patients, enabling faster  
and better-informed treatment decisions.  
For patients, this means a greater chance of recovery with less long-term  
harm to the kidney function. For healthcare systems, earlier intervention  
may reduce the cost of prolonged treatment and hospital stays, and  
the long-term burden of chronic kidney disease.  
BioPorto's ambition is to transform kidney care globally - making early,  
actionable diagnosis the standard of care in every critical care unit, in  
every country.  
4
BioPorto A/S  
2025 Annual Report  
 
Message from the  
Chair and the CEO  
Kidney health is increasingly recognized as a global public health priority. In 2025,  
the World Health Organization (WHO) adopted a resolution aimed at reducing  
the burden of kidney disease by promoting of kidney health and strengthening  
prevention and control efforts worldwide.  
This underscores the critical role kidney health plays for patients, healthcare systems,  
and society at large; and it strongly resonates with BioPorto’s purpose: To improve  
kidney health and enhance patients' quality of life.  
With our flagship biomarker, NGAL, BioPorto is uniquely positioned to make a  
meaningful difference for clinicians and patients by enabling earlier and more  
informed clinical decision-making within kidney care and especially in relation to  
Acute Kidney Injury (AKI). In essence BioPorto aspires to ensure that clinicians can  
know earlier, can manage better and with confidence.  
Performance 2025  
Guided by our purpose, 2025 was a highly eventful year. Throughout the year, we  
stayed firmly focused on strengthening our commercial foundation especially in  
the US market and advancing our clinical study of ProNephro AKI® (NGAL test) for  
adult use in the US, while simultaneously navigating significant organizational  
changes within the Board of Directors and Executive Management. This positions  
the Company for continued growth and stronger execution.  
Overall, BioPorto delivered a solid performance in 2025. We achieved 11% sales  
growth, mainly driven by continued growth in our research use only NGAL business  
in the United States. At the same time, we reported an adj. EBITDA loss of DKK 76.5m,  
reflecting our deliberate investments in strategic milestones as we keep pursuing  
our clinical study for adult use and the further expansion of our commercial reach.  
Jens Due Olsen & Carsten Buhl  
Chairman of the Board & Chief Executive Officer  
5
BioPorto A/S  
2025 Annual Report  
 
A key strategic milestone, was the commercial launch of  
ProNephro AKI® on the Roche Cobas® c 501 module for the  
US pediatric market during Q3 2025. This launch aligns with  
our ambition to establish a commercial platform for kidney  
diagnostics and drive broad adoption of ProNephro AKI,  
the NGAL biomarker focused on AKI within the intensive  
care settings at hospitals globally. We will continue working  
to expand the commercial availability of ProNephro AKI to  
additional instruments within the Roche family as well other  
instrument manufacturers and thereby further broadening the  
commercial platform and addressing a large customer base.  
The expansion will take place in parallel with the company  
driving demand for the NGAL biomarker at leading tier-one  
hospitals.  
is well positioned to cover our financial needs through 2026  
and in a favorable position as we pursue positive cash flow  
in the second half of 2027.  
The ”ForwardStrategy and Aspirations towards  
2028  
In November 2025, we refined our strategy with an increased  
focus on execution over the next three years. Our focus is  
on driving market adoption of the NGAL biomarker based  
primarily on research use only in the US, capturing high  
growth in North America and the EU, and expanding our  
addressable market.  
Finally, we would like to thank all of our employees, customers,  
distributors, partners from a clinical point of view and commer-  
cially, and our shareholders for their continued confidence in  
BioPorto. We are proud of the progress made during 2025 and  
with confidence look into an exciting 2026 with significant  
milestones ahead.  
With this renewed and refined focus on execution, we will  
closely monitor key milestones relating to our commercial  
progress and aspire to deliver:  
Positive Cash Flow in the second half of 2027  
Revenue in FY 2028 between DKK 150-200 million  
Adjusted EBITDA-margin in FY 2028 of at least 15%  
The patient enrolment in our clinical cut-off study was  
successfully completed at the end of October 2025. As  
informed in the beginning of November, the subsequent  
enrolment data collection and therefore the analysis had  
taken longer than expected. To ensure an optimal design  
and regulatory alignment for the validation study, BioPorto  
plans to submit a pre-submission to the U.S. Food and  
Drug Administration (FDA) following the completion and  
analysis of the cut-off study dataset in the first quarter of  
2026. Accordingly, the initiation of the validation study was  
postponed until after the pre-submission process has been  
finalized. This approach supports the aims of a robust and  
well-prepared pathway toward regulatory approval in 2027.  
Jens Due Olsen  
Chairman of the Board  
Carsten Buhl  
Chief Executive Officer  
Funding  
Among the year’s significant achievements were two  
successful private placements in April 2025 and November  
2025, raising a total of approximately DKK 77 million. We  
are deeply grateful for the strong support shown during  
this process from our existing shareholders as well as new  
investors.  
The funding rounds were completed at market price and  
attracted participation from both larger existing shareholders  
and new institutional and private investors, complemented by  
a strong commitment from BioPorto’s Board of Directors and  
Executive Management. With the funding secured, BioPorto  
6
BioPorto A/S  
2025 Annual Report  
 
Consolidated Financial Highlights  
2025  
2024  
2023  
2022  
2021  
2025  
2024  
2023  
2022  
2021  
Jan 1-Dec 31 Jan 1-Dec 31 Jan 1-Dec 31 Jan 1-Dec 31 Jan 1-Dec 31  
Jan 1-Dec 31 Jan 1-Dec 31 Jan 1-Dec 31 Jan 1-Dec 31 Jan 1-Dec 31  
DKK MILLION (except where noted)  
Income Statement  
Revenue  
DKK MILLION (except where noted)  
Cash Flow  
40.3  
36.2  
31.0  
29.0  
24.3  
Cash flows from operating activities  
Cash flows from investing activities  
(77.1)  
1.3  
(83.6)  
1.2  
(55.5)  
(0.3)  
(52.5)  
(0.5)  
(64.6)  
(0.4)  
Gross profit  
30.3  
24.5  
20.2  
19.0  
15.0  
Of which investment in property, plant,  
and equipment  
Sales and marketing costs  
Research and development costs  
Administrative costs  
27.2  
50.5  
38.9  
-
30.2  
33.5  
36.2  
-
18.9  
25.4  
21.2  
34.9  
17.4  
30.3  
32.7  
-
0.0  
71.9  
(3.9)  
(0.4)  
75.5  
(6.9)  
(0.0)  
40.8  
(0.4)  
88.7  
35.7  
(0.1)  
1.1  
Cash flows from financing activities  
Net cash flows  
36.0  
41.8  
(14.9)  
(63.9)  
Lease impairment  
1.0  
2.6  
Other  
Loss before financial items (EBIT)  
(86.1)  
(75.5)  
(61.2)  
(81.5)  
(65.3)  
Revenue growth  
11%  
75%  
67%  
46  
17%  
68%  
71%  
38  
7%  
65%  
67%  
31  
19%  
66%  
65%  
32  
5%  
62%  
57%  
29  
Financial items, net  
Loss before tax  
Net loss  
(1.5)  
(87.6)  
(82.1)  
1.7  
(73.7)  
(68.2)  
(0.0)  
(61.2)  
(56.3)  
(0.0)  
(81.5)  
(75.9)  
1.4  
(63.8)  
(57.1)  
Gross profit percentage  
Equity ratio (solvency)  
Average number of employees  
Number of shares at the end of the period  
(1,000)  
495,109  
429,670  
379,670  
334,693  
267,754  
Comprehensive loss  
(79.8)  
(69.5)  
(55.9)  
(76.0)  
(58.3)  
Adjusted EBITDA  
(76.5)  
(70.6)  
(56.1)  
(67.3)  
(62.0)  
Earnings/(Loss) per share* (EPS), DKK  
Net asset value per share, period-end, DKK  
Share price, period-end, DKK  
(0.15)  
0.13  
(0.17)  
0.16  
(0.16)  
0.16  
(0.24)  
0.21  
(0.21)  
0.17  
Assets and Liabilities  
Non-current assets  
Cash and cash equivalents  
Current assets  
1.02  
1.55  
2.09  
2.32  
2.47  
8.2  
54.9  
85.0  
93.2  
12.1  
59.7  
83.9  
96.0  
7.5  
66.4  
82.3  
89.8  
7.2  
81.8  
17.1  
45.5  
64.2  
81.3  
*
Loss per share (EPS) is calculated in accordance with IAS 33 “Earning per share. Other financial ratios have been calculated as shown in the Finan-  
cial Ratio section below.  
101.4  
108.6  
Total assets  
Adjusted EBITDA  
Equity  
63.0  
4.1  
67.8  
7.8  
60.2  
4.3  
70.2  
7.4  
46.0  
10.5  
24.8  
81.3  
Loss before financial items (EBIT)  
Depreciation and amortization  
Share-based compensation expenses  
Severance costs  
(86.1)  
2.5  
(75.5)  
2.4  
(61.2)  
2.7  
(81.5)  
4.0  
(65.3)  
4.3  
Non-current liabilities  
Current liabilities  
Total equity and liabilities  
26.1  
93.2  
20.4  
96.0  
25.4  
89.8  
31.0  
(0.6)  
7.7  
(0.9)  
3.4  
1.4  
7.6  
(1.0)  
-
108.6  
-
-
Lease impairment  
-
-
1.0  
2.6  
-
Adjusted EBITDA  
(76.5)  
(70.6)  
(56.1)  
(67.3)  
(62.0)  
7
BioPorto A/S  
2025 Annual Report  
 
Financial outlook for 2026  
As announced on February 5, 2026, BioPorto is targeting a total  
revenue of DKK 48-58m, which corresponds to a growth rate in  
the range of 20-45%.  
DKK 48-58m  
total revenue for 2026  
The growth will be driven by increased total NGAL revenue in  
the range DKK 33-42m, which corresponds to a growth rate of  
20-50%. This is primarily driven by an increase in active hospitals  
in U.S., where we are pursuing +60 active hospitals.  
For 2026, an adjusted EBITDA* loss in the range DKK 50-60m is  
expected. The lower expected loss compared to 2025 results from  
higher revenues and reductions in the overall cost base compared  
to 2025 and an expectation that the validation study will continue  
throughout 2026 and into first half of 2027.  
DKK 33-42m  
total NGAL revenue for 2026  
DKK 50-60m  
adjusted EBITDA* loss expected for 2026  
*Adjusted Earnings Before Interest, Taxes, Depreciation and Amortization (Adjusted EBITDA) is an alternative measure of performance  
utilized by management, investors and investment analysts to evaluate and analyze the Company’s results. Adjusted EBITDA excludes  
non-cash share-based compensation and non-recurring costs (e.g. merger, severance and acquisition integration costs).  
Adjusted EBITDA is a non-IFRS financial measure that does not have a standard meaning prescribed by IFRS and may not be defined and  
calculated by other companies in the same manner and thus may not be comparable with such measure.  
8
BioPorto A/S  
2025 Annual Report  
 
Aspirations Towards 2028  
The Aspirations towards 2028 was defined as part of the  
“Forward” strategy plan and is setting ambitious financial  
targets for the next three years.  
For 2026, the main growth driver is expected to be NGAL  
in the U.S. for Research Use Only (RUO). Further, while  
commercialization of The NGAL TestTM and ProNephro AKI  
(NGAL) will be the primary contributor for growth, BioPorto  
expects stable revenue from its antibodies business.  
For 2026 BioPorto expects the US market for NGAL  
through Research Use Only (RUO) will continue to  
be the main growth driver.  
The aspirations include:  
Positive Cash Flow in the second half of 2027.  
Revenue in FiscalYear 2028 between DKK 150-200 million.  
Adjusted EBITDA-margin in Fiscal Year 2028 of at least  
15%.  
Capital Requirements  
BioPorto's financing requirement is strongly dependent on  
commercial traction and top-line performance for the next few  
years. The successful funding of app. DKK 43m in November  
2025 covers projected costs for 2026.  
The fulfillment of these aspirations is strongly dependent on:  
Increased market adoption, especially in the US in the  
short term, which is reliant on the inclusion of kidney  
damage biomarkers in Kidney Disease: Improving Global  
Outcomes (KDIGO) guidelines, anticipated in the first  
part of 2026.  
The expansion of the addressable market through  
instrument expansion by current and potentially new  
strategic distributors, together with an anticipated U.S.  
FDA regulatory submission in 2027 for ProNephro AKI®  
(NGAL) in adults.  
The gap until cash flow positive expected in the second  
half of 2027 amounts to app. DKK 20-30m. The Company’s  
range of future financing options continues to be matured to  
secure funding for 2027, in the form of potential divestments  
of non-core assets supplemented with credit facilities and  
other financing solutions.  
The sales process and account management success in  
the US Market as a guide to drive the use of NGAL for  
testing pediatric and adult patients throughout the rest  
of the world.  
9
BioPorto A/S  
2025 Annual Report  
 
Strategy  
The “Forwardstrategy plan unlocking a USD 700m  
addressable market potential for NGAL tests  
THE THREE MILESTONES OF THE "FORWARD" STRATEGY IN 2026-2028:  
With the achievement of FDA clearance for ProNephro AKI® NGAL in US for  
pediatric (patients aged 3 months through 21 years) in December 2023, BioPorto  
started the journey of changing the focus from being a diagnostic innovator  
and a research-based company to becoming a commercial growth company.  
2026  
Building Market Adoption for  
BioPorto’s NGAL test  
In November 2025, theForwardstrategy was established with a strengthened  
commercial mindset. The “Forward” strategic plan focuses on building market  
adoption, capturing high growth and expanding the addressable market during  
the next three years with distinct milestones every year.  
2026 - Building Market Adoption for BioPortos NGAL tests  
2027  
Increase market adoption in the US  
Reach +60 active hospitals in the US  
Initiate the clinical validation study for adults  
Capturing High Growth within  
the Addressable Market of USD  
700m  
2027 - Capturing High Growth within the Addressable Market of  
USD 700m  
Increase market adoption in the EU  
Reach +100 active hospitals globally  
FDA submission for adults by first half of 2027 & EU IVDR in 2027  
2028  
Accelerate Growth  
Expanding Addressable Market &  
2028 - Expanding Addressable Market & Accelerate Growth  
Expand market adoption in the EU  
Reach +170 active hospitals globally  
Unlock broader market potential by targeting new segments  
10  
BioPorto A/S  
2025 Annual Report  
 
Strategy (continued)  
For 2026, the target is to succeed in building market adoption, as the Company will build on its  
US commercial execution. The Company plans to strengthen its core competencies and expand  
business development resources to set up the organization for future growth. U.S. hospital adoption  
is growing quarter over quarter, driven by expanding research use only (RUO) deployments and  
uptake following the end of 2023 FDA clearance of ProNephro AKI for pediatric use.  
A key component in the Company’s commercialization strategy is to secure strategic partnerships  
with instrument manufacturers and thereby drive product adoption. These collaborations will  
enable more laboratories to easily adopt and utilize BioPorto’s biomarker more rapidly. The goal  
is to have over 60 active hospitals across the US by the end of 2026. In 2025, we had 44 active  
hospitals across the US.  
The goal for 2027 is to achieve high growth, as the Company will apply US market learnings  
to its European go-to-market strategy. Growth efforts will focus on a few targeted European  
markets, utilizing clinical education and business development resources. Preparation for the EU  
IVDR certification is underway to meet anticipated demand and facilitate market growth. IVDR  
certification is expected in 2027.  
Market penetration will continue in both pediatrics and adultssegments, particularly as the future  
enhanced clinical guideline (KDIGO) is expected to gain traction and drive increased adoption. The  
goal is to reach +100 hospitals actively using the Company’s products globally by the end of 2027.  
The current addressable market of USD 700m focus on ICU, however in 2028 the aim is to expand  
the addressable market, as the Company intends to broaden its product portfolio, to address  
additional clinical settings where the NGAL biomarker is relevant. The Company plans to expand  
into new areas through label expansions and product development, both in-house and through  
partnerships, to further improve kidney health and patients’ quality of life. Continued market  
penetration with current products empower our goal of having +170 active hospitals globally by  
the end of 2028.  
11  
BioPorto A/S  
2025 Annual Report  
 
Commercial Go-to-Market Strategy  
The primary target accounts and customers for BioPorto’s commercial activities are nephrologists, cardiologists,  
intensivists and laboratory directors at large hospitals and medical centers  
The commercial go-to-market strategy for the pediatric  
launch of ProNephro AKI® (NGAL) has three focus areas:  
1. Peer-to-Peer  
3. Clinical Representatives  
Leveraging Key Opinion Leaders (KOLs) and other experts  
end users of NGAL to describe the value of using NGAL  
tests in daily practice to other doctors through publications,  
events, webinars, testimonials, and presentations at scientific  
meetings.  
BioPorto has a dedicated team with clinical and laboratory  
experience, enabling it to engage with physicians at prospective  
accounts and hold detailed clinical discussions about the  
product and its use. The team can also connect prospective  
customers with reference customers who champion the NGAL  
test or use NGAL-based products. This will also help to ensure  
alignment and buy-in among all decision makers in the hospital  
system.  
In addition to the increased marketing and sales  
activities, BioPorto is participating in the open comment  
process of KDIGO’s AKI guidelines update. KDIGO (Kidney  
Disease: Improving Global Outcomes) is the leading  
global organization developing and implementing  
evidence-based clinical practice guidelines in kidney  
disease. The next open comment period is expected  
spring 2025 and BioPorto plans to pursue including  
ProNephro AKI (NGAL), which is the first AKI biomarker  
test cleared for pediatric and young adult use in the US,  
in KDIGO’s highly regarded and important guidelines  
for AKI.  
2. Medical Affairs team  
Having a dedicated Medical Scientific Affairs (MSA) team is  
critical to furthering deep clinical discussions with doctors.  
The MSA team at BioPorto consists of experts with advanced  
degrees, such as PhDs and PharmDs, who can engage in  
scientific discourse on the use of NGAL in the medical  
management of Acute Kidney Injury (AKI). They support  
institutions in the development of their own process and  
protocols to guide hospitalsimplementation of new NGAL  
test-based kidney biomarker programs.  
In addition to the increased marketing and business  
development activities, BioPorto is participating in the open  
comment process of KDIGO’s AKI guidelines update. KDIGO  
(Kidney Disease: Improving Global Outcomes) is the leading  
global organization developing and implementing evidence-  
based clinical practice guidelines in kidney disease.  
12  
BioPorto A/S  
2025 Annual Report  
 
Instrument Expansion Strategy  
An important element in BioPorto’s commercialization plan  
is to secure strategic distribution partnerships with clinical  
chemistry instrument manufacturers to drive instrument  
expansion that are FDA cleared for ProNephro AKI® (NGAL)  
use to enable more laboratories to implement the test and  
hence increase the serviceable market. In August 2025, the  
delivery of the first ProNephro AKI (NGAL) order to the US  
market, marked the first step in the commercial launch via a  
strategic distribution partnership.  
In 2026, BioPorto plans to engage in more strategic distribution  
partnerships especially with current collaboration partners  
to ensure broadened and faster market access on more  
instruments. Further, the on-going dialog with new potential  
and additional leading instrument manufacturers to enable  
further use of ProNephro AKI (NGAL) on their platforms will  
be pursued in parallel.  
Following the first FDA clearance, the Company can conduct  
validation work and file to expand the marketing authorization  
to include additional instruments for the US market. These  
subsequent submissions will follow FDA guidance offered  
through pre-submission meetings. These are expected to be  
510(k) submissions, leveraging the pediatric data and samples  
if needed, and expanding indications with additional clinical  
study data, such as our U.S. FDA adult ICU study, initiated in  
late 2024.  
The primary focus is to engage with the global instrument  
manufacturers and BioPorto currently has agreement regarding  
Roche’s Cobas® c 501 analyzer in addition to the Cobas® c  
503 analyzer. Further, BioPorto entered a global distribution  
partnership with Beckman Coulter, a global diagnostics leader,  
to include DxC and AU clinical chemistry analyzers.  
13  
BioPorto A/S  
2025 Annual Report  
 
In Vitro Diagnostic Regulation (IVDR) important  
to gain further market access  
BioPorto currently generates revenue from The NGAL TestTM  
for research use only (RUO), for general use in the European  
Economic Area (EEA) under the CE-mark, and subject to local  
registration in Canada, Israel, and South Korea.  
also strengthening the local geographic distribution sales  
channels.  
From IVDD to IVDR  
In Europe, new EU regulations related to in vitro diagnostics  
devices (IVDR) partly entered into force in May 2022. The new  
regulation will replace the current CE-mark under IVDD for  
in vitro diagnostic devices. The IVDR transition deadline was  
extended by the European Parliament and the Council of the  
European Union and now runs to December 2028 for certain  
IVDs.  
The NGAL Test is currently available for In Vitro Diagnostic (IVD)  
use in Europe and other geographies under its CE-mark for all  
patient populations, disease states, and instruments.  
Commercially, IVDR approvals may help to drive demand as  
the lower requirements for clinical evidence of the former IVDD  
regulation may have caused physicians and laboratories to wait  
for better data for approval of specific tests and indications  
before considering clinical use.  
The IVDR regulations ensure higher safety and performance  
standards for diagnostics, covering everything from blood tests  
to genetic testing. Manufacturers, importers, and authorized  
representatives must adhere to these stricter rules to to main-  
tain access to promote in the EU market.  
BioPorto will take the necessary steps to apply in due time  
and expects that the experience gained and analytical study  
data created through the FDA submission and subsequent  
clearance of ProNephro AKI® (NGAL) for pediatric use will  
facilitate the process.  
The new regulation focuses on a new classification of IVDs into  
four risk classes, a more precise description of their analytical  
and clinical performance, more stringent requirements for the  
clinical evidence, more precise execution and planning of post  
market surveillance, as well as better traceability of IVDs and  
more transparency for patients.  
Combined with the Company’s marketing organization,  
BioPorto’s executive team will focus on activities to drive market  
adoption in targeted European markets, including extensive  
market education on AKI and the value of NGAL testing, while  
14  
BioPorto A/S  
2025 Annual Report  
 
Products and Market Position  
Novel kidney biomarkers, like Neutrophil Gelatinase  
A recent multicentre study evaluated the performance and  
stability of the ProNephro AKI® in pediatric patients, which  
showed excellent precision, reproducibility, sensitivity,  
specificity, and stability, meeting the required analytical  
performance for clinical use in diagnosing and managing  
AKI in critically ill pediatric patients16.  
The need for new kidney biomarkers  
Associated Lipocalin (NGAL) address these gaps by identifying  
structural tubular injury hours before functional decline  
occurs, enabling earlier diagnosis, better risk stratification,  
and more personalized intervention strategies11,12. Among  
the emerging markers evaluated in literature reviews and  
systematic assessments, NGAL consistently stands out as one  
of the most reliable, earliest, and best validated biomarkers  
of structural kidney injury, being strongly elevated during  
ischemic, toxic, or septic tubular injury, providing a direct  
Acute Kidney Injury (AKI) is a sudden loss of kidney function  
that affects about 13 million people globally and leads to  
1.7 million deaths each year1. In hospitals, AKI is commonly  
occurring in 20-25% of hospitalized patients2,3,4. It increases  
the risk of death, longer hospital stays and developing chronic  
kidney disease (CKD)5. AKI frequently arises in the context of  
severe illness or major interventions (such as surgery), but  
its early stages are often clinically silent, making it hard to  
detect quickly6.  
The NGAL Test and ProNephro AKI® (The NGAL  
Assays)  
BioPorto's NGAL Assays are a particle-enhanced immunoassay  
(biochemical test) that measures the concentration of NGAL  
in human plasma or human urine on widely used chemistry  
analyzers like Roche Cobas®, Siemens Atellica®, and Abbott  
Alinity®, integrating easily into hospital laboratory workflows.  
No proprietary instruments or additional capital purchases  
are needed, streamlining adoption and sales. Moreover, this  
allows seamless integration into routine laboratory workflows  
with near real time reporting.  
measure of kidney cell damage10,13  
.
Current tests, such as measuring increase in serum creatinine  
or reduced urine output, are slow to show changes and may  
miss early kidney damage7. Serum creatinine may not rise  
until ~50% of kidney function is lost and is affected by factors  
like muscle mass and hydration, often delaying diagnosis  
by 24-48 hours7. Reduced urine output can also result from  
non-kidney conditions like sepsis, dehydration, heart failure,  
liver disease, or severe low blood pressure8. This means that  
structural kidney injury can happen without immediate  
changes in these markers, leading to delayed recognition  
The NGAL biomarker in a nutshell  
NGAL is an early and sensitive marker for detecting structural  
kidney injury, especially AKI. Unlike traditional markers such  
as serum creatinine, which rise late and is influenced by  
many factors, NGAL levels increase rapidly after kidney  
damage, allowing clinicians to identify AKI much sooner.  
This enables earlier diagnosis, improved risk assessment, and  
better treatment decisions, such as distinguishing between  
different AKI types and predicting when dialysis can be safely  
stopped14, 15. NGAL is now routinely used in clinical practice  
and is backed by strong scientific evidence for its reliability  
and utility.  
and missed opportunities for early intervention9 10  
.
1. Lameire, N. H. et al. Lancet 382, 170–179 (2013)., 2. Susantitaphong, P. et al. Clin. J. Am. Soc. Nephrol. 8, 1482–1493 (2013)., 3. Esposito, P. et al. Clin. Kidney J. 17, sfae231 (2024)., 4. Chisavu, F. et al. Sci. Rep. 13, 15778 (2023)., 5. Hoste, E. A. J. et al. Intensiv. Care Med. 41,  
1411–1423 (2015)., 6. Kellum, J. A. et al. Nat. Rev. Dis. Prim. 7, 52 (2021)., 7. Matarneh, A. et al. Ren. Fail. 47, 2556295 (2025)., 8. Ostermann, M., Shaw, A. D. & Joannidis, M. Intensiv. Care Med. 49, 103–106 (2023)., 9. Yang, H., Chen, Y., He, J., Li, Y. & Feng, Y. BMC Nephrol. 26, 115  
(2025)., 10. Virzì, G. M. et al. J. Clin. Med. 14, 1570 (2025)., 11. Almulhim, M. Y. PLOS One 20, e0311755 (2025)., 12. Ostermann, M. et al. Ann. Intensiv. Care 14, 145 (2024)., 13. Yang, H., Chen, Y., He, J., Li, Y. & Feng, Y. BMC Nephrol. 26, 115 (2025)., 14. Côté, J.-M. et al. Nephron  
146, 306–314 (2022)., 15. Ceschia, G. et al. Pediatr. Res. 1–6 (2025) doi:10.1038/s41390-025-04430-1., 16. Malaeb, H. et al. Clin. Chim. Acta 120511 (2025) doi:10.1016/j.cca.2025.120511.  
15  
BioPorto A/S  
2025 Annual Report  
 
Recent 3rd party studies address how NGAL helps  
in clinical practice  
NGAL helps guiding when to stop dialysis safely  
Improving the Diagnosis of AKI Types with NGAL  
Stopping dialysis (Renal Replacement Therapy, RRT) at the right  
time is crucial for patients with severe kidney injury. If dialysis  
continues too long, it can cause infections, bleeding, unstable  
blood pressure, slower kidney recovery, and higher healthcare  
costs19. That’s why doctors need reliable tools to know when  
it’s safe to stop.  
Urinary NGAL (uNGAL) testing helps doctors quickly determine  
whether a patient’s AKI is caused by direct structural damage  
to the kidneys or by other, less severe factors like dehydration,  
heart problems, or liver disease. Traditional tests, such as serum  
creatinine or urine sodium measurements, often cannot make  
this distinction14.  
Recent research shows that a simple urine test for the NGAL  
biomarker can help. Studies in critically ill patients found that  
NGAL levels predict when dialysis can be safely stopped20.For  
children, a study led by Dr. Giovanni Ceschia defined the NGAL  
value for successful RRT liberation15.  
Recent clinical studies, including one at St. Vincent's University  
Hospital in Ireland, show that uNGAL is much better at telling  
apart these different types of AKI. If the NGAL level is below a  
certain threshold, it effectively rules out serious intrinsic kidney  
damage, allowing doctors to focus on treating other, reversible  
causes. This means patients can receive the right treatment, like  
fluids or blood pressure medications, more quickly and avoid  
unnecessary interventions17.  
Although larger prospective studies are needed to confirm these  
findings, the results strongly suggest that NGAL is a valuable  
tool to support bedside decisions in pediatric AKI management,  
while addressing a critical gap in RRT discontinuation protocols.  
NGAL testing is also especially valuable for patients with liver  
cirrhosis, who are at higher risk for AKI. In these patients, it is very  
difficult to distinguish between two common causes of kidney  
problems: HepatoRenal Syndrome (HRS), which is a functional  
issue, and Acute Tubular Necrosis (ATN), which involves real  
structural damage to the kidneys. Standard tests cannot tell them  
apart, but NGAL levels are much higher in cases of ATN. Using a  
specific NGAL cut-off value, doctors can reliably tell if the kidney  
damage is structural or not. This guides them to the most effective  
treatments since some therapies only work for functional problems  
like HRS and not for structural damage like ATN18.  
NGAL testing is now moving from research labs into hospitals,  
helping doctors make fast, informed decisions. This means safer  
care and better outcomes for patients with AKI.  
University Hamburg-Eppendorf (UKE)  
(Hamburg, Germany)  
NGAL implementation and validation finished in late  
2025. Pediatric nephrology and transplantation clinicians  
are now selecting at-risk patient groups to start routine  
use soon. NGAL is expected to help detect AKI risk earlier,  
allowing timely intervention and improved outcomes in  
children.  
In summary, adding NGAL testing to routine AKI assessment  
means faster, more accurate diagnosis, and ensures patients get  
the treatment that best fits their condition.  
17. Strader, M. et al. Kidney360 (2025) doi:10.34067/kid.0000000887., 18. Phukan, C. et al. BMC Gastroenterol. 26, 16 (2025)., 19. Boyer, N., et al. Curr. Opin. Crit. Care 29, 559–565 (2023)., 20. Xu, Q. et al. Crit. Care 29, 213 (2025).  
16  
BioPorto A/S  
2025 Annual Report  
 
Significant market potential  
Investing in BioPorto - Investing in AKI Diagnostics  
The total available market for the NGAL Assays are estimated at USD 3 billion based  
on internal market analyses. Of this amount, approximately 22% is considered  
addressable within the Intensive Care Unit NGAL segment.  
Early detection of AKI (Acute Kidney Injury) represents a  
major unmet need21.  
BioPorto’s ProNephro AKI® (NGAL) is the first FDA-cleared  
test for pediatric AKI assessment.  
Defined pathway for FDA approval and commercial launch of  
ProNephro AKI (NGAL) for adults in US to open addressable  
market.  
Worldwide  
market  
Significant market potential – Total targeted ICU (Intensive  
Care Unit) Market estimated at app. USD 700m22.  
USD~0.7bn  
USD~3.0bn  
Growth Case based on an asset light business model with  
high margins and clear value drivers towards 2028.  
ICU NGAL segment  
Total market potential for The NGAL Assays  
21. NephroCheck at 10: addressing unmet needs in AKI diagnosis and risk stratification | Clinical Kidney Journal | Oxford Academic  
22. Source: Management estimates | S2N Data, BIS data | US Ped Risk Strat indication is for 3 months through 21yoa  
17  
BioPorto A/S  
2025 Annual Report  
 
ELISA Kits and Antibodies  
BioPorto's existing portfolio includes high-specificity mono-  
clonal antibodies - such as GLP-1 and other key antibodies  
- used across lifescience research.  
ELISA Kits  
BioPorto sells NGAL ELISA kits (Enzyme-Linked Immunosorbent  
Assay) for research use in humans and in five animal species,  
from mouse to monkey.  
BioPorto also provides in-house scaled-up production of  
antibodies in bulk volumes to meet specific customer needs,  
i.e., for diagnostic kit manufacturers.  
These ELISA kits target NGAL and help scientists bridge  
their development work from preclinical study to clinical  
development.  
Antibodies  
BioPorto provide antibodies to researchers around the world,  
leveraging our expertise to transform their research into  
strong reliable results.  
These research tools are commonly used to study kidney  
damage associated to nephrotoxicity kidney damage and to  
assess the effectiveness of new pharmaceutical compounds  
during development.  
BioPorto antibodies are frequently used to develop diagnostic  
immunoassays within several disease areas, including immu-  
nodeficiency, allergy, coagulation, diabetes, kidney, and  
cardiovascular disease.  
As these kits serve as research tools that could evolve into future  
products in the form of FDA-cleared actionable biomarkers,  
BioPorto continue to include ELISA Kits as a part of its product  
offering.  
BioPorto sells approximately 90 different antibodies against  
approximately 60 different targets.  
18  
BioPorto A/S  
2025 Annual Report  
 
Financial Review  
This financial review is based on the Group’s consolidated  
financial information for the year ended December 31, 2025,  
with comparative results for the year ended December 31,  
2024, in brackets. Preliminary unaudited financial figures,  
were announced on February 5. The final, audited financial  
figures are approximately equal to the preliminary previously  
announced.  
Revenue  
Revenue for 2025 was DKK 40.3 million (DKK 36.2 million),  
an increase of 11%, and at constant exchange rates a growth  
of 13%.  
FIGURE 2: NGAL test product revenue by quarter (DKK million)  
FIGURE 1: Revenue by quarter (DKK million)  
2025  
DKK million  
2024  
DKK million  
%
sales of DKK 4.3 million contributed to the overall NGAL  
revenue increase.  
based compensation expenses primarily from staff leaving  
the company and lower recruiting and consultancy costs,  
offset by the carry-over from end of 2024 of staffing up areas  
of business development and sales force to commercialize  
ProNephro AKI (NGAL) in the US.  
change  
Revenue Source  
US NGAL (RUO)  
ROW NGAL  
18.4  
5.5  
14.7  
8.4  
25%  
-35%  
-
Antibody revenue decreased by DKK 0.2 million, or 2%. ELISA  
kits revenue decreased by DKK 0.8 million, or 35%, compared  
to the prior year period.  
ProNephro AKI®  
(distributors)  
4.3  
0.0  
NGAL Total  
28.2  
10.6  
1.5  
23.1  
10.8  
2.3  
22%  
-2%  
-35%  
11%  
Research and Development Costs  
Research and development costs, consisting of reasearch and  
development, regulatory affairs, quality assurance, clinical, and  
medical affairs, totaled DKK 50.5 million (DKK 33.5 million).  
The increase was mainly driven by the adult clinical study.  
Antibody  
Gross Profit  
Gross profit for 2025 totaled DKK 30.3 million (DKK 24.5  
million), resulting in a gross margin of 75% (68%). The DKK  
5.8 million increase in gross profit was mainly driven by a  
favorable sales volume and efficiency gains.  
ELISA & other  
Total Revenue  
40.3  
36.2  
NGAL revenue increased by DKK 5.1 million, or 22%, over  
the prior year period. US NGAL revenue totaled DKK 18.4  
million, which is an increase of 25% over the prior year period  
primarily driven by NGAL (RUO) and revenue from strategic  
distributors. ROW NGAL revenue totaled DKK 5.5 million,  
which is a decrease of 35% of which DKK 2.4 million in 2024  
was sales through distributors. ProNephro AKI®(distributors)  
Administrative Costs  
Administrative costs totaled DKK 38.9 million (DKK 36.2  
Sales and Marketing Costs  
Sales and marketing costs totaled DKK 27.2 million (DKK 30.2  
million). The main movements were severance costs for the  
million). The decrease is mainly driven by reversal of share-  
19  
BioPorto A/S  
2025 Annual Report  
 
former CEO who resigned effective August 31, 2025, offset  
by reversal of warrant expense.  
credits derived by BioPorto’s Danish entities associated with  
investments in research and development.  
The Company’s assessment as to the adequacy of liquidity  
relies inter alia on assumptions and significant judgements  
(in addition to those matters discussed cf. Note 2) applied in  
the Company's budgets and forecasts as well as customary  
sensitivities, existing capital resources and assumptions  
concerning the timing, costs and resources required to  
undertake the Company’s strategic priorities and tactical  
decisions, including the timing of marketing ProNephro  
AKI® (NGAL) in the US, commercialization activities for NGAL  
tests under CE-mark and Antibodies in Europe, supply chain  
management, and ongoing R&D, all of which under current  
circumstances remain difficult to predict.  
Financials Items, Net  
EBIT/Adjusted EBITDA  
Financial income and expenses reflect interest income/  
expense and currency transaction gains/losses, bank charges  
and interest. In 2025 it was a net cost of approximately DKK  
1.5 million (DKK 1.7 million, income), with the net amount  
related to currency rate changes and interest income.  
For 2025, EBIT was a loss of DKK 86.1 million (DKK 75.5 million),  
Adjusted EBITDA was a loss of DKK 76.5 million (loss of DKK  
70.6 million), each reflecting the mix of variances described  
above.  
Guidance compared to realised - Realised is within latest  
guidance:  
Tax Benefit  
2025  
ORIGINAL  
GUIDANCE  
2025  
LATEST  
GUIDANCE  
Equity  
A DKK 5.5 million tax benefit (DKK 5.5 million tax benefit)  
was realized during 2025. The tax benefit is related to tax  
2025  
REALISED  
DKK million  
Total revenue  
At the end of 2025, equity totaled DKK 63.0 million (DKK  
67.8 million).  
45-60  
75-85  
40-45  
75-80  
40.3  
76.5  
Adjusted EBITDA loss  
In April 2025, BioPorto raised gross proceeds of DKK 33.5  
million and 25,000,000 new shares of commen stock were  
issued.  
In November 2025, BioPorto raised gross proceeds of DKK  
43,3 million and 40,438,426 new shares of commen stock  
were issued.  
Cash and Cash Equivalents  
As of December 31, 2025, BioPorto’s balance of cash and cash  
equivalents totaled DKK 54.9 million (DKK 59.7 million) and  
is deposited at major, national Danish, Nordic, and US banks.  
The Company continually evaluates its liquidity requirements,  
capital needs and availability of capital resources based on  
its operating needs and planned initiatives.  
See the Consolidated Statement of Changes in Equity below  
for further details in the movements in equity.  
The Company assessed its liquidity and capital resources,  
and concluded that they are adequate to fund operations  
considering a twelve-month period from the date of this  
Annual Report.  
20  
BioPorto A/S  
2025 Annual Report  
 
Net Working Capital  
Change of Control  
Net working capital (i.e., current assets minus current liabilities)  
as of December 31, 2025 totaled DKK 58.8 million (DKK 63.5  
million). The decrease is mainly related to increased trade  
payables and accrued liabilities.  
The Danish Financial Statements Act, Section 107 a, contains  
rules relating to listed companies with respect to certain  
disclosures associated with change of control provisions in  
contracts. BioPorto has entered into agreements with external  
parties that may be subject to renegotiation in the event of a  
change of control in BioPorto. However, detailed information  
is not provided here, as it may be restricted from disclosure  
due to confidentiality provisions or is not otherwise expected  
to have a material effect on the Company’s financial position.  
Cash Flow Statement  
Cash used in operating activities for the year ended December  
31, 2025, totaled DKK 77.1 million (DKK 83.6 million), with  
the decrease over the prior year primarily associated with  
the timing of account payables, offset by inventory change.  
Cash received from investing activities was DKK 1.3 million  
(received DKK 1.2 million) which primarily consisted of  
sublease receipts.  
Cash from financing activities was DKK 71.9 million (DKK  
75.5 million), reflecting the net proceeds from the private  
placements, offset by facility lease repayments.  
The net cash flow for the year ended December 31, 2025,  
reflected a use of DKK 3.9 million (use of DKK 6.9 million).  
Subsequent Events  
There are no subsequent events.  
21  
BioPorto A/S  
2025 Annual Report  
 
Risk Management  
Risk management is an integral  
part of BioPorto’s operations  
as well as financial and non-financial factors. The risk monitoring  
and management forms part of the ongoing risk assessment  
process and is part of the regular reporting to the Board of  
Directors. Overall, it aims to ensure a forward-looking and agile  
risk management approach that provides a holistic view of all  
risks across the organisation.  
BioPorto is exposed to a diverse set of risks that have  
the potential to significantly and adversely impact  
the business. The risks are effectively managed  
through a risk management framework ensuring  
the key risk factors are captured and the Company  
effectively can execute the strategy.  
Risk Factors  
In our risk reporting framework, we have identified a range of  
key risks, being material and have the potential to significantly  
and adversely impact the business.  
Governance and Risk reporting process  
Risk Management is an integral part of the operations and  
part of the Rules of Procedures for the Audit Committee. The  
Board of Directors holds overall responsibility for performing  
risk oversight, while the CFO is responsible for assessing and  
facilitating the prioritization of the key risks. Together, the Board  
of Directors and the Executive Management at least twice a  
year review and define the overall risk profile and agree on  
the key risks and actions related hereto.  
In 2026, the key risks relate to market acceptance, manufacturing  
and supply, conducting clinical studies related to adults,  
obtaining regulatory approvals and ensuring sufficient funding.  
To the extent these risk factors are within the Company’s control,  
the Company seeks to address them in the ordinary course  
of business.  
The risk management framework enables the Company to  
identify, assess and mitigate potential business risks. The  
approach involves considering internal and external factors  
22  
BioPorto A/S  
2025 Annual Report  
 
Risk Factors and Mitigation  
Market  
Acceptance  
FDA Adult Study  
and Submission  
Manufacturing  
The Company’s products and future products may fail to  
achieve the degree of market acceptance by physicians,  
laboratory management, healthcare payors and others in  
the medical community necessary for commercial success  
and market penetration may be lengthy and difficult. A  
failure to successfully commercialize NGAL tests for pediatric  
and adult uses would have a material adverse effect on the  
Company’s future revenues, future growth prospects, future  
cash-flows and future results of operations.  
The Company’s products are complex to manufacture, and  
the Company is, in some instances, reliant on sole source  
suppliers. The Company may encounter difficulties in  
manufacturing that could have a material adverse effect  
on the Company’s revenues, cash flow, results of operations  
and future growth prospects.  
The Company is currently conducting a clinical trial to obtain  
regulatory clearance for adult use of NGAL in the US. Timing  
of future clinical trials depends on many factors outside of  
the Company’s control, including regulatory pathways and  
their conditions associated with submissions presently under  
review that will serve as predicates to other submissions.  
Further, there is no guarantee that the submission will be  
approved by the FDA and result in a regulatory clearance.  
Training of Commercial and Medical Liaison personnel,  
strengthening of Health Economics and outcomes  
Research (HEOR) sales enablement tools and preparation  
of reimbursement dossiers to payers and institution  
administration (U.S. specific), providing marketing material  
directed at clinicians on use cases for NGAL, pursuing IIS  
programs for publication on NGAL protocols and preparing  
KDIGO Guideline public responses.  
Maintaining a good and productive relationship with sole  
suppliers and securing in-house qualified production  
leadership and personnel to investigate alternatives for  
derisking the supply chain.  
Aligning with competent Contract Research Organizations  
and having internal R&D talent that can effectively and  
efficiently manage ongoing and future clinical trials. Further,  
the Company will leverage its knowledge obtained from the  
previous regulatory clearance for pediatric use obtained in  
December 2023.  
23  
BioPorto A/S  
2025 Annual Report  
 
Risk Factors and Mitigation (continued)  
Instrument Expansion  
Financing  
An important element in BioPorto’ s commercialization  
plan is to secure expansion of instruments that are FDA  
cleared for ProNephro AKI® (NGAL) use to enable more  
laboratories to implement the test and hence increase the  
serviceable market. The Company may not be able to conduct  
the planned instrument expansion and thereby increase  
the serviceable market according to the plan. A failure to  
successfully perform instrument expansion would have a  
material adverse effect on the Company’s future revenues,  
growth prospects, cash-flows and results of operations.  
To achieve its strategic objectives, the Company will require  
additional capital to fund its operations, which may not be  
available to the Company on acceptable terms.  
Currently, operations are financed through 2026.  
Close collaboration with the instrument vendors to ensure a  
fast and efficient process. Further, internally deploy dedicated  
resources to drive and prepare materials for the submissions  
to the FDA.  
Executing the financing strategy to generate further investor  
interest and potential funding. Multiple financing options  
are available, including financing from share issuance, debt  
financing and financing from spinning off the Antibody  
business.  
24  
BioPorto A/S  
2025 Annual Report  
 
Internal Controls  
BioPorto’ s Board of Directors and Management oversee  
control and risk management for financial reporting and  
compliance. The Audit Committee reviews accounting and  
audit practices with the Company’s auditors and Management  
as per its Rules of Procedure.  
At least once a year, the Audit Committee evaluates risks in  
financial reporting, internal controls, and guidelines. This  
includes assessing organizational structure, fraud risks, and  
measures to counteract such risks, including any incentives  
for Management to manipulate financial reporting.  
Internal controls and guidelines aim to prevent unlawful  
asset use, loss, and significant errors in financial reporting,  
offering reasonable but not absolute certainty. The Board  
decided that BioPortos size and complexity do not warrant  
an internal audit function.  
25  
BioPorto A/S  
2025 Annual Report  
 
Governance  
Corporate Governance  
27  
28  
Board of Directors  
& Executive Management  
26  
BioPorto A/S  
2025 Annual Report  
 
Corporate  
Governance  
BioPorto remains focused on good corporate governance, having imple-  
mented all, except for three recommendations from the Committee of  
Corporate Governance (Komitéen for god selskabsledelse) for companies  
listed on the Nasdaq Copenhagen Stock Exchange. Details can be found  
in the Corporate Governance report.  
The Board of Directors believes that the Company operates in compliance  
with guidelines and recommendations that support the Company’s business  
model and can create value for BioPorto’s stakeholders.  
Regularly and at least once a year, the Board of Directors monitors adherence  
to the recommendations on corporate governance to ensure appropriate  
utilization of and compliance with the recommendations and legislation.  
In accordance with Section 107b of the Danish Financial Statements Act,  
BioPorto has published a statutory report on Corporate Governance for  
the financial year 2025 on the Company’s website.  
Find out more about BioPorto at  
bioporto.com/corporate-governance  
Executive Team  
Carsten Buhl, Gry Louise Husby Larsen & Niels Høy Nielsen  
27  
BioPorto A/S  
2025 Annual Report  
 
Board of Directors & Executive  
Management  
BioPorto is managed in a two-tier structure composed of the Board  
of Directors and the Executive Management  
Board of Directors  
Board of Directors makes decisions on all unusual matters or  
matters with far-reaching implications. The Board of Directors  
defines guidelines for the distribution of responsibilities  
between the Board of Directors and Executive Management  
but does not participate in the day-to-day management of the  
Company. The duties of the Board of Directors are described  
in the Rules of Procedure.  
The General Meeting elects between three and seven  
members to the Board of Directors, which currently consists  
of four members. The Board of Directors elects a chairperson  
and a vice chairperson. Members hold office for terms of one  
year at a time and may be re-elected. Members of the Board  
are nominated and stand for election based on their specific  
qualifications and of relevance to BioPorto. The Board of  
Directors is composed of providing a combination of relevant  
industry experience and functional experience. All current  
Board members, except for Donna Haire, are considered  
independent persons and can thus act independently. Each  
Board member’s qualifications are listed on the Company’s  
website.  
The Board is responsible for the overall  
strategic management and the financial  
and managerial supervision of BioPorto, and  
regular evaluation of Executive Management.  
Executive Management  
The Executive Management is appointed by the Board of  
Directors, which lays down the Executive Managements terms  
and conditions of employment and the framework for their  
duties. The Executive Management is responsible for the day-  
to-day management of the Company in compliance with the  
guidelines and directions issued by the Board. The day-to-day  
operations do not include transactions of an unusual nature  
or of material importance to the affairs of the Company.  
The Board is responsible for the overall strategic management  
and the financial and managerial supervision of BioPorto, and  
regular evaluation of Executive Management. The Board of  
Directors also ensures that the Company is properly managed  
as required by the Articles of Association, other guidelines,  
policies and applicable rules and regulations. Furthermore, the  
28  
BioPorto A/S  
2025 Annual Report  
 
Board of Directors  
Jens Due Olsen  
Henrik Juuel  
Chairman of the Board  
Vice Chairman of the Board  
Year of birth  
Nationality  
Gender  
1963  
Danish  
Male  
2025  
2026  
Yes  
Year of birth  
Nationality  
Gender  
1965  
Danish  
Male  
2024  
2026  
Yes  
First elected  
Term expires  
Independent  
Experience  
First elected  
Term expires  
Independent  
Experience  
Jens Due Olsen has over 30 years of experience in leadership positions in Danish  
and international industrial, financial and technology companies, including  
medico technology. Jens currently serves as the Chair of the Board of Directors  
at NKT Holding and the privately owned European Energy A/S. Jens also holds  
the position of Vice Chair of the Board of Directors at KMD A/S, a subsidiary of  
NEC Corp. Inc., and has advisory roles with several private equity and venture  
capital firms, including JOLT S.A. Additionally, Jens is Chair of the not-for-profit  
organization Børnebasketfonden and the Danish football initiative "Hele  
Danmarks Klubhus". Jens Due Olsen has previously held leadership and executive  
positions at A.P. Moller-Maersk, FLSmidth and GN Store Nord, amongst others.  
Henrik Juuel is the Executive Vice President and Chief Financial Officer in Bavarian  
Nordic since 2018. Prior to Bavarian Nordic, he served as CFO in Orexo AB and  
held senior positions at several large and diverse organizations including Group  
CFO of Virgin Mobile (Central and Eastern Europe), CFO of GN ReSound, and CFO  
of NNE Pharmaplan. Henrik began his career at Novo Nordisk in 1992, and during  
his 15-year tenure with the company held several senior finance positions in  
Denmark and abroad. Henrik holds a M.Sc. in Economics and Finance.  
Other  
directorships  
None  
Other  
directorships  
NKT A/S (Chair), European Energy A/S (Chair), KMD A/S (Vice Chair), Non-profit  
organization "Børnebasketfonden" and "Hele Danmarks Klubhus" (Chair)  
29  
BioPorto A/S  
2025 Annual Report  
 
Board of Directors (continued)  
Mats Thorén  
Donna Haire  
Board Member  
Board Member  
Overview of  
BioPorto Shares  
Year of birth  
Nationality  
Gender  
1971  
Swedish  
Male  
2024  
2026  
Yes  
Year of birth  
Nationality  
Gender  
1969  
Number of Shares held at  
Jens Due Olsen  
Henrik Juuel  
Dec 31, 2025 Dec 31, 2024  
American  
Female  
2025  
5,783,136  
839,440  
448,195  
-
-
First elected  
Term expires  
Independent  
Experience  
First elected  
Term expires  
-
2026  
Mats Thorén  
214,987  
-
No - In 2023 & 2024, Donna Haire provided consultancy  
services for the Company in connection with the pedi-  
atric US FDA clearance, and is thus not considered inde-  
pendent according to the Danish Corporate Governance  
Recommendations.  
Donna Haire  
Mats Thorén has 25 years of financial market experience,  
specializing in healthcare through roles in equity  
analysis and corporate finance. He has spent 19 years as  
a Healthcare investment expert, working with firms like  
Nalka Life Science AB and MedCap AB, and now leads  
Vixco Capital. His educational background includes  
Economics, focusing on Accounting and Financial  
Economics, and medical studies at the Karolinska  
Institute in Stockholm.  
Independent  
Experience  
Resigned Board Members  
Donna Haire is an accomplished board director and  
executive leader with 30+ years of experience in global  
healthcare, pharmaceuticals, and medical devices. She is  
the CEO of The Eriah Group, Inc. and COO of FluoGuide  
A/S, and serves on the board of Sedana Medical AB. She is  
a former board member of FluoGuide A/S. Donna has held  
executive and senior roles in regulatory, quality, clinical,  
and medical affairs at Bayer, On Target Laboratories,  
AngioDynamics, Philips Healthcare, Medtronic, and STERIS,  
and has served as a U.S. regulatory expert in international  
trade negotiations. She served on AdvaMed’s Technical  
and Regulatory Board Committee and was an Adjunct  
Professor at the University of Akron School of Law. She  
holds an M.S. in Biology from Cleveland State University  
and a B.S. in Biology from The University of Akron.  
John McDonough  
Resigned 31 January 2025  
175,000  
175,000  
Don Hardison  
Resigned 11 April 2025  
20,000  
20,000  
Other  
directorships  
FluoGuide A/S (Vice Chair), Xbrane BioPharma AB (Board  
member), Arcoma AB (Board member), Herantis Pharma  
Oy (Board member), C-Rad (Board member)  
Michael Singer  
Resigned 11 April 2025  
-
-
-
Ninfa Saunders  
Resigned 11 April 2025  
-
Other  
Sedana Medical AB (Board Member)  
directorships  
30  
BioPorto A/S  
2025 Annual Report  
 
Executive Management  
Carsten Buhl  
Niels Høy Nielsen  
Gry Husby Larsen  
Chief Executive Officer  
Chief Financial Officer  
Chief Legal Officer  
Year of birth  
Nationality  
Gender  
1973  
Danish  
Male  
Year of birth  
Nationality  
Gender  
1970  
Danish  
Male  
Year of birth  
Nationality  
Gender  
1980  
Danish  
Female  
2011  
Joined BioPorto  
Experience  
2025  
Joined BioPorto  
Experience  
2024  
Joined BioPorto  
Experience  
Carsten Buhl was appointed Chief Executive Officer of  
BioPorto effective September 1, 2025. He brings over 25 years  
of leadership experience in the MedTech and Life Science  
industries. Prior to joining BioPorto, Carsten served as President  
of the Americas at WSAudiology, where he was a member  
of the executive management team. His career also includes  
senior leadership roles at Natus Medical Inc., Ambu, and GN  
Store Nord, among others. Carsten is recognized for his deep  
expertise in general management and his global perspective,  
having led and transformed teams across multiple continents.  
He has a proven track record in scaling businesses, executing  
go-to-market strategies, launching innovative products, and  
driving operational excellence. He holds a Master of Law from  
Copenhagen University and an Executive MBA.  
Niels Høy Nielsen is a highly skilled leader with over 20 years  
of leadership experience in finance, operations, mergers and  
acquisitions, and capital markets. He recently joined BioPorto  
Gry Husby Larsen has been with BioPorto since 2011, initially  
as General Counsel, where she led the company's legal and  
HR activities, including compliance, fundraising, intellectual  
property rights, contracts, Board support, HR, and ESG.  
From 2019-2024, Gry served as an external General Counsel  
for BioPorto while also holding part-time General Counsel  
positions at FluoGuide A/S, Algiecel A/S, and Unibio A/S, as  
well as conducting consultancy work through HUSBY ApS.  
Before joining BioPorto, Gry was an Attorney-at-law at Knop &  
Co. Law Firm. Her extensive legal and commercial experience  
in the biotech industry is a significant asset in the growth and  
development of BioPorto. Gry holds a Master of Law degree  
from the University of Copenhagen.  
from ChemoMetec A/S,  
a
Danish Nasdaq-listed Medtech  
company, where he served as CFO since 2022. Before that,  
Niels was the VP of Finance at Convatec, Infusion Care, a global  
provider of medical products focused on the management  
of chronic conditions. During his decade-long tenure at  
LEO Pharma A/S, he led departments in finance, sales, and  
manufacturing. Prior to his tenure with LEO Pharma, he  
worked 7 years within investment banking at Jyske Bank and  
Svenska Handelsbanken. Niels holds a Master of Science in  
Finance and Accounting from the Aarhus School of Business  
and has supplemented his education with leadership training  
at IMD.  
Other  
directorships  
HUSBY ApS (CEO)  
Other  
directorships  
Fuglevad Holding ApS (CEO), Fuglevad Invest ApS (CEO)  
Other  
None  
directorships  
31  
BioPorto A/S  
2025 Annual Report  
 
Board Committees  
Overview of meetings in 2025  
Attended  
Absent  
Not on the committee/board  
As of 31 December 2025 and as of the date of the  
Annual Report, the Board of Directors consisted of  
four board members, of which three are male and  
one is female. A total of 22 Board meetings were held  
in 2025: 13 Board meetings were originally planned  
for in 2025 according to the Boards Annual Schedule  
and additionally 9 meetings were held following up  
on company related matters, issuing Warrants, and  
adopting capital increases. 13 meetings are initially  
planned for 2026 in accordance with the Board of  
Directors’ annual schedule, which can be altered at  
any time to allow for additional meetings, if deemed  
necessary.  
Nomination &  
Remuneration  
Committee  
Audit  
Committee  
PDS  
Committee  
Board Member  
Board of Directors  
John McDonough  
Resigned 31 January 2025  
N/A  
N/A  
N/A  
N/A  
N/A  
N/A  
Don Hardison  
Resigned 11 April 2025  
N/A  
Michael Singer  
Resigned 11 April 2025  
N/A  
Ninfa Saunders  
Resigned 11 April 2025  
N/A  
N/A  
Henrik Juuel  
Re-elected 11 April 2025  
Mats Thorén  
Re-elected 11 April 2025  
To support the Board in its duties, the Board has  
established and appointed the following committees  
and respective members that are tasked with reviewing  
issues pertaining to their respective fields that are due  
to be considered at board meetings. As of the date  
of publication of the Annual Report the following  
committees are established:  
Jens Due Olsen  
Elected 11 April 2025  
N/A  
N/A  
Donna Haire  
Elected 11 April 2025  
N/A  
Nomination & Remuneration Committee  
Mats Thorén*  
Jens Due Olsen  
Audit Committee  
Henrik Juuel*  
Mats Thoren  
More information about the committees,  
including the terms of reference that  
specify their tasks and responsibilities, is  
available on the Company’s website.  
Product Development & Strategy Committee  
Donna Haire*  
Jens Due Olsen  
* indicates the independent chair of each committee  
32  
BioPorto A/S  
2025 Annual Report  
 
which was updated in 2023, and subsequently approved by  
the shareholders at the Annual General Meeting in 2023.  
In accordance with section 139b in the Danish Companies  
Act, BioPorto has prepared a Remuneration Report on the  
remuneration of the individual members of the Board and  
the Executive Management in 2025.  
BioPorto has adopted a Data Ethics Policy cf. section 99 d of  
the Danish Financial Statements Act which set out BioPorto’s  
approach to data ethics and describe the ethical principles that  
BioPorto and its group companies must adhere to when using  
data and applying new technologies. BioPorto is dedicated to  
ensuring strong data ethics based on the following principles:  
Evaluation of the Performance  
of the Board of Directors and the  
Executive Management  
Annually, the Board of Directors conducts a self-evaluation of  
the Board's performance and composition. The Chair heads the  
annual evaluation, which at least every third year is conducted  
by an external consultant. The process, whether it is facilitated  
internally or by external consultants, evaluates topics such as  
board dynamics, board agenda, quality of the material that is  
submitted to the Board, discussions at the Board meetings, the  
Chair’s leadership of the Board, strategy, Board composition  
and Board competencies. Typically, the process is further  
facilitated by each Board member completing a detailed  
questionnaire, and the Board members are asked to score to  
which extent they agree to the individual questions.  
1. Responsible and accountable data processing  
2. Transparency  
3. Data quality awareness and integrity  
4. Security  
Business Ethics  
The Company has established a Code of Conduct that is  
made available to external stakeholders via the Company’s  
website. Likewise, the Company has established  
a
5. Ethical data processing carried out by third parties  
Whistleblower Scheme that is available to all employees in  
the BioPorto Group, both were reviewed and approved by  
the Board of Directors in 2025.  
Our Data Ethics Policy is available on BioPorto’s website.  
In 2025, we carried out initiatives to support our focus on  
protection of personal data and data ethics principles. All new  
and current employees received GDPR and data training as  
part of their introductory program in 2025 and continuous  
e-learning within the Company to maintain continuous  
attention to data protection and data ethics principles.  
We continued to implement enhancements to our policies  
and procedures to support the handling and processing of  
personal data.  
Tax Policy  
The results of the questionnaire are then discussed at a  
subsequent Board meeting, and the individual comments  
submitted are used in the planning and handling of future  
Board meetings. The 2025 self-evaluation was conducted  
internally, and the key conclusions were positive with  
continued satisfaction with the Board’s work as well as the  
work on the committees. Long term planning to secure future  
board competencies that align with the Companys future  
strategic direction and developement will be focus area in  
2026.  
The Board has adopted a Tax Policy describing the  
Company’s governing principles by which the Company  
manages its tax affairs.  
The Tax Policy is located on the Company’s website.  
The Board of Directors has adopted a policy on data  
ethics that is available on the Company’s website.  
Privacy, GDPR and Data Ethics  
BioPorto focuses on privacy and protection of personal data  
throughout the Company, covering the data of employees,  
partners, and other stakeholders. BioPorto has implemented  
strong measures to protect personal data and comply with the  
EU General Data Protection Regulation (GDPR) and national  
personal data protection legislation.  
Remuneration Policy  
and Report  
The remuneration of the Board and the Executive Mana-  
gement is governed by the Company’s Remuneration Policy,  
33  
BioPorto A/S  
2025 Annual Report  
 
Corporate Social  
Responsibility  
cf. Section 99a of the Danish  
Financial Statements Act  
UN Global Compact  
Diversity  
35  
37  
34  
BioPorto A/S  
2025 Annual Report  
 
BioPorto adheres to the 10 principles provided  
by the UN Global Compact, with the latest  
Communication on Progress available  
at United Nations Global compact  
UN Global Compact  
BioPorto is committed to our social responsibility and strives to  
improve social and environmental conditions  
UN Global Compact  
Human Rights  
Code of Conduct &  
BioPorto is committed to our social responsibility and strives  
to improve social and environmental conditions.  
1. Businesses should support and respect the protection  
of internationally proclaimed human rights; and  
2. make sure that they are not complicit in human rights  
abuses.  
Whistleblower Scheme  
Our compliance framework is anchored in the Code of  
Conduct, binding for all employees and integrated into  
supplier contracts. Training on human rights and compliance  
is part of onboarding and reinforced through The Company  
QMS.  
BioPorto adheres to the 10 principles provided by the UN  
Global Compact, with the latest Communication on Progress  
available at United Nations Global compact.  
BioPorto actively supports and respects internationally  
recognized human rights and labor standards. The Company  
oppose all forms of discrimination and ensure equal treatment  
regardless of gender, age, ethnicity, disability, religion, or  
personal beliefs.  
BioPorto complies with the Section 99a of the Danish Financial  
Statements Act of 2018.  
The Whistleblower Scheme, implemented in 2023, provides  
a secure channel for reporting unethical behavior, including  
harassment, discrimination, and violence of Code of Conduct.  
No incidents were reported in 2025, underscoring our  
commitment to transparency and accountability.  
In some areas, BioPorto fulfills its responsibility solely by  
complying with current law. In other areas, the Company’s  
responsibility has been expanded to include preventive  
activities. It is important to BioPorto to share these efforts  
to ensure that the outside world can have confidence in the  
Company and that we live up to our social responsibility.  
Key 2025 Highlights:  
Zero human rights violations recorded.  
Annual review and Board approval of our Code of  
Conduct.  
Clinical Trials  
Continued operation of the Whistleblower Scheme,  
ensuring confidential reporting of concerns.  
BioPorto conducts clinical trials with the highest ethical and  
scientific standards. Following the first patient enrollment  
in our Adult Clinical Study in 2024, trials continued in 2025  
with zero reported violations. Participant safety remains our  
top priority.  
BioPorto's ongoing participation in the UN Global Compact  
reinforces these principles as a global standard for social  
engagement.  
Looking ahead to 2026, BioPorto will continue to strengthen  
internal controls, enhance governance processes, and  
promote a safe, inclusive workplace through collaboration  
with the statutory Work Environment Group.  
35  
BioPorto A/S  
2025 Annual Report  
 
We continue to promote diversity and gender balance across  
all levels.  
BioPorto enforces a zero-tolerance policy on corruption,  
bribery, and money laundering. All employees receive anti-  
corruption training during onboarding and regular training  
after.  
Human Rights Initiatives  
In 2026, BioPorto will continue to build upon its human rights  
framework, promoting our Whistleblower Scheme to ensure  
even greater accessibility and confidentiality for employees.  
The Company aim to foster an environment where human  
rights are at the forefront of all our operations. Through  
collaboration with theWork Environment Group and Corporate  
Affairs, the Company will ensure that policies and practices  
not only comply with legal requirements but also reflect our  
dedication to ethical leadership and corporate responsibility.  
Environment  
BioPorto's operations have a limited environmental footprint;  
however, we remain committed to minimizing impact and  
promoting sustainable practices in line with the UN Global  
Compact principles:  
In 2025:  
Updated Code of Conduct and training programs to  
strengthen awareness.  
Zero corruption incidents reported.  
7. Support a precautionary approach to environmental  
challenges.  
8. Undertake initiatives to promote greater environmental  
responsibility.  
9. Encourage the development and diffusion of environ-  
mentally friendly technologies  
Risks  
Labor Rights  
BioPorto's risk of impacting human rights, environment, or  
anti-corruption remains low. Risks are assessed annually  
based on operational significance and stakeholder impact.  
No material risks have been identified.  
3. Businesses should uphold the freedom of association  
and the effective recognition of the right to collective  
bargaining;  
2025 Highlights:  
4. the elimination of all forms of forced and compulsory  
labor;  
5. the effective abolition of child labor; and  
6. the elimination of discrimination in respect of employ-  
ment and occupation.  
Continued preparations for CSRD compliance, while  
awaiting the outcome of the Omnibus Directive to finalize  
reporting requirements.  
Continued initiatives to reduce energy and water  
consumption and foster climate-friendly practices across  
all operations.  
In summary, BioPorto remains committed in our efforts  
to uphold the highest standards of ethical conduct,  
environmental conduct, and inclusivity as we keep our  
ongoing commitment to transparency, accountability and  
continuous improvement. Moving forward, we will continue  
to embed these principles into our operations, championing a  
workplace and corporate culture defined by respect, diversity,  
and integrity. Together, we continue to build a stronger future  
for BioPorto and all those we serve.  
BioPorto upholds freedom of association, prohibits forced  
labor and child labor, and enforces anti-discrimination policies.  
Our Code of Conduct extends these standards to suppliers.  
BioPorto acknowledges its relatively small environmental  
footprint but remains committed to continuous improvement.  
Any environmental incident would be reported immediately to  
executive management, with corrective actions implemented  
to prevent recurrence. No environmental incidents were  
reported in 2025.  
2025 Initiatives:  
Launched quarterly engagement surveys.  
Completed statutory workplace assessment (APV) with  
follow-up actions planned for 2026.  
For further details on BioPorto’s broader business  
risks, refer to the Risk Management section of this  
Annual Report.  
Recorded one minor work-related injury (slip accident),  
reported and resolved through statutory channels.  
Zero union-related cases.  
Anti-Corruption  
10. Businesses should work against corruption in  
all its forms, including extortion and bribery.  
36  
BioPorto A/S  
2025 Annual Report  
 
Diversity  
In pursuit of fostering an inclusive and equitable workplace  
environment, BioPorto’s commitment to diversity remains steadfast  
BioPorto’s Diversity Policy  
Grounded in our core values of equality, respect, and integrity  
and to support our continued work regarding diversity in 2026  
BioPorto’s Board of Directors has adopted the following Policy:  
Diversity at Management and Board Level  
Governance, Responsibilities and Review  
The Board of Directors annually:  
BioPorto recognizes that diversity at leadership level is  
essential to sound governance and effective oversight. The  
Company therefore aims to promote balanced representation  
and diversity at all management levels, including Executive  
Management and the Board of Directors.  
Reviews the Company’s diversity policy and its relevance  
Assesses progress against the Company’s diversity  
ambitions and disclosed targets  
“BioPorto is committed to fostering a diverse, inclusive and  
equitable workplace across all entities in the Group. We believe  
that diversity of gender, age, nationality, cultural background,  
educational and professional experience, perspectives and  
skills strengthens decisionmaking, promotes innovation and  
supports longterm value creation in a highly regulated and  
knowledgedriven biotech environment.  
Evaluates whether existing initiatives and processes  
support sufficient diversity at management levels  
The Board of Directors is responsible for setting the overall  
framework and ambition for diversity at leadership level and for  
ensuring that diversity considerations form an integral part of:  
Executive Management is responsible for implementing the  
diversity policy through recruitment, talent management,  
leadership development and workplace practices, supported  
by Group HR.  
This policy is reviewed at least annually and updated as required  
to reflect changes in legislation, governance requirements or  
business priorities."  
Board composition, succession planning and nomination  
processes  
Executive appointment and development decisions  
Talent, leadership and succession pipelines within the  
Group  
BioPorto is committed to ensuring equal opportunities for all  
employees and applicants and does not tolerate discrimination  
based on, inter alia, gender, gender identity or expression,  
age, nationality, ethnicity, religion or belief, sexual orientation,  
disability or other characteristics.  
Central to our commitment is the principle that all employees  
should be valued and recognized for their unique perspectives,  
talents, and contributions. We reject the notion of "fitting in" and  
instead, champion a culture where every voice is heard, every  
perspective is respected, and every individual is empowered  
to thrive. As part of our ongoing efforts, BioPorto's Board of  
Directors diligently reviews and evaluates our diversity initiatives  
annually, reaffirming our dedication to fostering an inclusive  
workplace where diversity is not just a goal but a lived reality.  
BioPorto has established measurable diversity targets for the  
Board of Directors, which are disclosed in the Annual Report,  
page 38. Progress against these targets is reviewed regularly  
and reported transparently.  
Employees shall be recognized and evaluated based on  
competence, performance and potential, and we believe that  
individuals should be recognized because of, not despite,  
their diversity.  
37  
BioPorto A/S  
2025 Annual Report  
 
Diversity in the BioPorto Group  
of the Company’s Board of Directors changed as three Board  
Members stepped down and two new Board Members were  
elected at the Annual General Assembly. Following a thorough  
candidate selection process with a strong emphasis on gender  
diversity, the highly qualified candidates Jens Due Olsen and  
Donna Haire were presented to the AGM for election.  
Executive Management and Other Layers of Management  
at BioPorto A/S  
In 2025, we noticed changes in our workforce composition  
that affected both the gender-balance as well as the diversity  
landscape. The proportion of male employees decreased from  
46% to 41%. Additionally, the representation of non-Danish  
employees decreased from 69% to 63%.
We remain committed  
to fostering a workplace where individuals from diverse  
backgrounds can
thrive, make meaningfully contributions,  
and collectively drive our shared success.  
The Company has not set a target for the unrepresented  
gender in the Executive Management and other layers of  
the Management team, as the Company’s size is below the  
minimum thresholds of 50 employees or more cf. guidelines  
from the Danish Business Authority, section 4.1.2. The  
Company has adopted a general Diversity Policy cf. above,  
but the Company is below the threshold of 50 employees  
or more cf. guidelines from the Danish Business Authority,  
section 4.2 and accordingly not obligated to adopt a Policy.  
However, the company has decided to maintain its goal  
that by 2027, at least 40% of the Board of Directors will be  
comprised of the underrepresented gender, achieving equal  
representation according to applicable law. This commitment  
underscores our belief in promoting gender equality without  
compromising the selection of the most qualified individuals  
for these critical roles. This target is not intended to detract  
from other competency requirements in the nomination of  
members to the Management team of the Company.  
Dec 31, 2025 BioPorto  
Group  
Non-  
Danish  
Female  
59%  
Male  
41%  
All Employees (46 persons)  
63%  
0%  
As of 31 December 2025, and as of the date of this Annual  
Report the following information applies to the Executive  
Management.  
Executive Management  
(3 persons)  
33%  
25%  
67%  
75%  
BioPorto A/S Board of Directors  
(4 persons)  
50%  
Executive  
Management  
2023  
1
2024  
3
2025  
3
2026  
2027  
Furthermore, the representation of non-Danish members on  
the Board is 50%, highlighting the Company’s dedication to  
integrating global perspectives and insights. This composition  
ensures a broader range of viewpoints at the highest levels  
of governance, strengthening strategic decision-making and  
alignment with international best practices.  
Number of Members  
Diversity in the Board of Directors of BioPorto A/S  
Diversity in the composition of the Board is sought, with a  
reasonable age composition, several nationalities, and an  
equal gender ratio. The Board currently has four members,  
of which three are male and one is female.  
Underrepresented  
gender in %  
0% /  
100%  
33%  
33%  
Target date  
N/A  
N/A  
N/A  
N/A  
N/A  
N/A  
Target number in %  
BioPorto currently meets the Danish Business Authority's re-  
quirement for an equal gender ratio. In 2025, the composition  
As of 31 December 2025, the following information applies to  
the Board of Directors.  
Board of Directors  
2023  
5
2024  
6
2025  
4
2026  
2027  
The Nomination & Remuneration Committee has a policy  
for evaluating candidates of both genders for vacant Board  
positions. For future vacant Board positions, the Nomination &  
Remuneration committee will continue to evaluate candidates  
of both genders.  
Number of Board  
Members  
Underrepresented  
gender in %  
20%  
17%  
25%  
Target date  
2027  
40%  
2027  
40%  
2027  
40%  
Target number in %  
38  
BioPorto A/S  
2025 Annual Report  
 
Shareholder  
Matters  
Investor Relations  
40  
41  
42  
Shares  
Dividend Policy, Analysts & Meetings  
39  
BioPorto A/S  
2025 Annual Report  
 
Investor Relations  
BioPorto maintains an active dialogue with shareholders,  
analysts, prospective investors, and other stakeholders by  
communicating relevant strategic, economic, financial, opera-  
tional, and scientific affairs of the Company. Management  
and Investor Relations are routinely available to existing  
and potential shareholders via participation in investor con-  
ferences, roadshows, investor meetings, and conference calls.  
Other published information, including general Company  
and investor presentations, is made available to the public on  
the Company’s website. The investor section of the website  
also includes an email service where shareholders and others  
can subscribe to receive news by email immediately after  
the publication of Company announcements, press releases,  
and other news.  
Access BioPorto investor information and sub-  
scribe to Company announcements  
https://bioporto.com/investor-relations/  
BioPorto aims to provide the market with transparent  
and adequate information about the Company’s strategy,  
operations and results ensuring fair pricing of its shares. BioPorto  
operates in a highly complex sector in terms of both products  
and market conditions. The Company endeavors to strike a  
reasonable balance so that the information it communicates  
is both technically correct and understandable to laypeople.  
All stakeholders should have rapid, equal access to material  
information about BioPorto’s development and growth.  
Registered shareholders are offered a range of electronic  
information services through the shareholder portal, which  
can be accessed from the Company’s website. The portal  
also offers the opportunity to request admission cards and/  
or vote by proxy for the General Meetings. Shareholders are  
encouraged to sign-up to receive Company announcements  
via e-mail from the Company, which can be done in the link  
below. Investor Relations (IR) is responsible for ensuring that  
information from the group’s IR stakeholders is shared with  
the Management and the Board of Directors.  
This means, among other things, that relevant  
information is published in Company  
Announcements via NASDAQ Copenhagen A/S  
and is made available on the group’s website.  
For more relevant details relating to BioPorto,  
investors are referred to the Company’s website.  
40  
BioPorto A/S  
2025 Annual Report  
 
Shares  
Capital Stock  
To support efficient, expedient dialogue with shareholders,  
BioPorto encourages its shareholders to let their shareholding  
be registered and to participate in BioPorto’s shareholder  
meetings.  
On December 31, 2025, BioPorto’s capital stock had a nominal  
value of DKK 495,108,887 divided into 495,108,887 shares  
with a nominal value of DKK 1 each. Each share carries  
one vote. BioPorto A/S’s shares are listed on NASDAQ  
Copenhagen.  
As of December 31, 2025, BioPorto had 17,860 registered  
shareholders (2024: 19,472) As of December 31, 2025, the  
following shareholders stated that they owned 5% or more  
of the Company’s shares/voting rights.  
In April 2025, BioPorto completed a private placement of  
25,000,000 new shares raising gross proceeds of DKK 33.5  
million.  
Further, in November 2025, BioPorto completed an additional  
private placement of 40,438,426 new shares raising gross  
proceeds of DKK 43.3 million.  
Ownership  
Ejendomsselskabet Jano ApS  
12.1%  
Toldbodgade 36A, Copenhagen K  
Other published information, including general Company  
and investor presentations, are available to the public on  
the Company’s website. The investor section of the website  
also includes an email service where shareholders and others  
can subscribe to receive news by email immediately after  
the publication of Company announcements, press releases  
and other news.  
Media-Invest Danmark A/S  
11.1%  
Gammel Kongevej 174, 4., Frederiksberg C  
AL Sydbank A/S  
5.4%  
Peberlyk 4, 6200 Aabenraa  
Get stock details and access the shareholder por-  
tal on the Company website  
41  
BioPorto A/S  
2025 Annual Report  
 
Dividend Policy, Analysts & Meetings  
Dividend Policy  
Annual Shareholder Meeting  
Given the Company’s need for capital to implement its  
strategic initiatives and achieve higher sales, no dividend  
is expected to be paid in 2026. In the long term, and as the  
Company generates profits, the Company will evaluate at  
the appropriate time its ability to give shareholders direct  
returns in the form of dividends and/ or share buybacks in  
addition to a return on the share price.  
BioPorto A/S will hold its annual shareholder meeting on April  
24, 2026, at 3:00 pm CET at the company’s address: Tuborg  
Havnevej 15, DK-2900 Hellerup. Additional information will  
become available on the Company’s website no later than  
three weeks before the Annual General Meeting.  
Information on shareholder meetings  
can be found on our website  
Equity Analysts and  
Investor Meetings  
FINANCIAL CALENDAR 2026  
BioPorto has ongoing contacts with investors and equity  
analysts and, in this context, holds regular presentations  
and meetings where strategy, pipeline development and  
risks are discussed. BioPorto usually holds investor meetings  
after the publication of the annual report, interim reports  
and quarterly announcements.  
March 12, 2026  
Deadline for shareholder proposals –  
Annual General Meeting  
March 26, 2026  
April 24, 2026  
May 21, 2026  
Annual Report 2025  
Annual General Meeting  
Interim Report – for the three-month  
period ended March 31, 2026  
The following analyst covers BioPorto (Non-commissioned  
research):  
August 20, 2026  
Interim Report – for the six-month  
period ended June 30, 2026  
November 19, 2026  
Interim Report – for the nine-month  
period ended September 30, 2026  
H.C. Wainwright, US – Mr. Yi Chen  
42  
BioPorto A/S  
2025 Annual Report  
 
Financial  
Statements  
Consolidated Financial Statements  
44  
48  
77  
80  
Notes to Consolidated Financial Statements  
Parent Company Financial Statements  
Notes to Parent Company Financial Statements  
43  
BioPorto A/S  
2025 Annual Report  
 
Consolidated Financial Statements  
Consolidated Statement of  
Comprehensive Loss  
Consolidated Statement of Loss  
2025  
2024  
2025  
2024  
DKK THOUSAND  
DKK THOUSAND  
Notes  
Jan 1-Dec 31  
Jan 1-Dec 31  
Net loss  
(82,117)
(68,243)
Revenue  
3
40,287
9,895
36,243
11,713
24,530
30,202
33,533
36,247
(75,452)
2,543
Other comprehensive loss:  
Amounts which will be reclassified to the  
income statement:  
Production costs  
4, 5, 6  
Gross profit  
30,392
27,162
50,468
38,856
(86,094)
511
Sales and marketing costs  
Research and development costs  
Administrative costs  
Loss before financial items (EBIT)  
Financial income  
4, 5, 6  
4, 5, 6  
4, 5, 6  
Exchange rate adjustments of foreign subsidiaries  
2,276
(1,277)
Other comprehensive income/(loss)  
2,276
(1,277)
Comprehensive loss  
(79,841)
(69,520)
8
8
Adjusted EBITDA  
2025  
(86,094)  
2,508  
2024  
(75,452)  
2,382  
Financial expenses  
Loss before tax  
Income tax benefit, net  
Net loss  
2,054
834
Loss before financial items (EBIT)  
Depreciation and amortization  
Share-based compensation expenses  
(87,637)
5,520
(73,743)
5,500
9
(637)  
(875)  
(82,117)
(68,243)
Severance costs  
7,690  
3,421  
DKK  
DKK  
Adjusted EBITDA  
(76,533)  
(70,525)  
Earnings/(Loss) per share (EPS & DEPS)  
10  
(0.15)
(0.17)
44  
BioPorto A/S  
2025 Annual Report  
 
Assets  
Equities and Liabilities  
2025  
2024  
2025  
2024  
DKK THOUSAND  
Non-current assets  
Property, plant and equipment and intan-  
gible assets  
Notes  
DKK THOUSAND  
Notes  
17  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Equity  
Share capital  
495,109
1,224
429,670
(1,052)
Foreign currency translation reserve  
(loss)/income  
Rights and software  
11  
12  
13  
138
1,520
4,825
276
2,136
6,579
Accumulated deficit  
(433,324)
(360,868)
Property, plant and equipment  
Total equity  
63,009
67,750
Right-of-use assets  
Total property, plant and equipment  
and intangible assets  
6,483
8,991
Liabilities  
Non-current liabilities  
Lease liabilities - Non-current  
Total non-current liabilities  
Financial assets  
13  
4,049
7,846
Lease receivable - Non-current  
Deposits  
18  
393
1,348
1,741
8,224
1,707
1,387
4,049
7,846
Total financial assets  
Total non-current assets  
3,094
12,085
Current liabilities  
Current portion of lease liabilities  
Trade payables  
13  
18  
16  
3,471
14,021
8,632
3,344
11,326
5,718
Current assets  
Other accrued liabilities  
Total current liabilities  
Inventories  
14  
9,249
9,437
4,640
8,187
26,124
20,388
Trade receivables  
Current tax receivable  
Other receivables  
Prepayments  
15, 18  
6,797
6,392
Total liabilities  
30,173
28,234
15, 18  
15  
1,165
1,368
Total equity and liabilities  
93,182
95,984
2,292
2,448
Lease receivable - Current  
Cash and cash equivalents  
Total current assets  
18  
1,125
1,200
18  
54,893
84,958
59,664
83,899
Total assets  
93,182
95,984
45  
BioPorto A/S  
2025 Annual Report  
 
Consolidated Statement of Changes in Equity  
Foreign currency translation  
reserve  
DKK THOUSAND  
Share Capital  
Share Premium  
Accumulated Deficit  
Total  
Balance at December 31, 2024  
Net loss  
429,670
-
-
-
(360,868)
(82,117)
-
(1,052)
-
67,750
(82,117)
2,276
-
-
Other comprehensive income/(loss)  
2,276
Transactions with owners:  
Issuance of Stock  
65,439
-
11,416
(1,118)
-
-
-
-
76,855
(1,118)
Issuance costs  
Transferred to Accumulated Deficit  
Share-based compensation  
-
-
(10,298)
-
10,298
(637)
-
-
-
(637)
Balance at December 31, 2025  
495,109
-
(433,324)
1,224
63,009
Foreign currency translation  
reserve  
DKK THOUSAND  
Share Capital  
Share Premium  
Accumulated Deficit  
Total  
Balance at December 31, 2023  
Net loss  
379,670
-
-
-
(319,763)
(68,243)
-
225
-
60,132
(68,243)
(1,277)
-
-
Other comprehensive income/(loss)  
(1,277)
Transactions with owners:  
Issuance of Stock  
50,000
-
31,400
(3,387)
-
-
-
-
81,400
(3,387)
Issuance costs  
Transferred to Accumulated Deficit  
Share-based compensation  
Balance at December 31, 2024  
-
-
(28,013)
28,013
(875)
-
-
-
(875)
-
429,670
-
(360,868)
(1,052)
67,750
46  
BioPorto A/S  
2025 Annual Report  
 
Consolidated Statement of Cash Flows  
2025  
2024  
2025  
2024  
DKK THOUSAND  
Notes  
DKK THOUSAND  
Notes  
13  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Loss before financial items  
(86,094)
(75,452)
Proceeds from shares issue  
76,855
(1,118)
(3,798)
71,939
81,400
(3,387)
(2,547)
75,466
Cost related to Issue of new shares  
Repayments of lease obligation  
Cash flows from financing activities  
Adjustments:  
Depreciation and amortization  
Share based compensation expenses  
Other non-cash items(1)  
6
4
2,508
(637)
2,216
-
2,382
(875)
Net cash flows for the period  
(3,852)
(6,930)
(1,400)
(984)
Remeasurement of lease  
13  
Cash and cash equivalents  
at beginning of period  
59,664
66,402
Changes in operating assets and liabilities:  
Inventories  
Effect of exchange rate changes on cash  
(919)
192
(4,883)
(1,233)
2,695
(864)
(5,847)
(6,819)
78
Trade receivables  
15  
13  
Cash and cash equivalents end of period  
54,893
59,664
Trade payables  
(1) Other non-cash items primarily consist of the recognition of provisions related to the tax receivable, financial items, the  
leasing receivable, the lease liabilities, and the development in the inventory impairment.  
Other operating assets and liabilities, net  
Cash flows from operations  
2,771
(82,657)
(89,781)
Financial income, received  
Financial expenses, paid  
Tax refund, net  
347
(205)
1,641
(381)
5,449
4,938
Cash flows from operating activities  
(77,066)
(83,583)
Purchase of property, plant and equipment  
-
(350)
Proceeds from (purchase of) nancial assets  
Proceeds from sublease  
-
756
781
1,275
Cash flows from investing activities  
1,275
1,187
47  
BioPorto A/S  
2025 Annual Report  
 
Notes to Consolidated Financial Statements  
1. Basis of Reporting  
Report is therefore prepared in the XHTML format, which can  
be displayed in a standard browser. The primary statements  
and the notes in the consolidated financial statements are  
tagged using the inline eXtensible Business Reporting  
Language (iXBRL). The iXBRL tags comply with the ESEF  
taxonomy, which is included in the ESEF Regulation and  
development based on the IFRS taxonomy published by the  
IFRS Foundation. Where a financial statement line item is not  
defined in the ESEF taxonomy, an extension to the taxonomy  
has been created. Extensions are anchored to elements in the  
ESEF taxonomy, except for extensions that are subtotals. The  
Annual Report submitted to the Danish Financial Supervisory  
Authority consists of the XHTML document together with  
certain technical files, all included in a file named BIOPORTO-  
2025-12-31-1-en.zip.  
Currency  
The Group’s consolidated financial statements are presented  
in Danish kroner (DKK), which is considered the primary  
currency of the Group’s activities and the functional currency  
of both the parent company and its most significant subsidiary.  
Figures are rounded to the nearest DKK thousand unless  
otherwise stated.  
Basis of Preparation  
The consolidated financial statements are prepared in  
accordance IFRS Accounting Standards as adopted by the  
EU and additional requirements of the Danish Financial  
Statements Act. The financial year for the Group is January  
1 - December 31.  
The consolidated and parent financial statements have been  
prepared on a going concern basis.  
Basis of Consolidation  
The consolidated financial statements are prepared as a  
consolidation of the financial statements of the Parent Company,  
BioPorto A/S,
and its subsidiaries in accordance with the  
Group’s accounting policies. All intra-group income, expenses,  
The accounting policies set out below have been used con-  
sistently with respect to the financial year and comparative  
figures. Certain comparative figures have been reclassified  
to conform to the current year’s presentation. The  
accounting policies have been applied consistently except  
that a reclassification has been made to ensure the correct  
presentation of accruals related to vendors. As a result,  
vendor-related accruals are now included in Trade Payables,  
while Other Payables primarily comprise accruals related to  
employees and public authorities. The reclassification is a  
presentation adjustment only and has no impact on profit  
or loss.  
Applying Materiality  
Material items are presented individually in the financial  
statements as required by IAS 1.  
Items that are not individually material but support the  
understanding of BioPorto’s business model and performance  
in the reporting period are presented in the financial  
statements.  
iXBRL reporting  
BioPorto
A/S
is required to file its annual report in the  
European Single Electronic Format ('ESEF'), and the Annual  
48  
BioPorto A/S  
2025 Annual Report  
 
1. Basis of Reporting (continued)  
shareholdings, balances, and dividends are eliminated on  
consolidation. The accounting items of subsidiaries are included  
in full in the consolidated financial statements.  
Implementation of new and amended standards and  
interpretations  
All new and amended Standards (IFRS/IAS) and the new  
Interpretations (IFRIC) issued by IASB and adopted by EU  
effective as of January 1, 2025, have been adopted by the  
BioPorto Group as applicable and did not have a material  
impact on the consolidated financial statements.  
Differences arising from the translation of the opening balance  
of equity of foreign entities at the exchange rates prevailing at  
the reporting date, and on translation of the income statement  
from the transaction date to the reporting date, are recognized  
in other comprehensive income and attributed to a separate  
translation reserve in equity.  
New standards and interpretations  
The IASB has issued new or amended accounting standards  
and interpretation that have not yet become effective and  
have consequently not been implemented in the Consolidated  
financial statements for 2025. BioPorto intends to adopt these  
new and amended accounting standards and interpretations,  
if applicable, when they become mandatory.  
Incentive programs  
The Company has issued warrants (options) to Management  
and employees. Share-based incentive programs in which  
employees only have the option of choosing to subscribe for  
new shares in the parent Company (equity-settled share-based  
payment transactions) are measured at the equity instrument’s  
fair value on the grant date and are recognized in the income  
statement over the vesting period. The counter entry for this  
is recognized directly in equity. Warrants restricted by vesting  
conditions are forfeited if the vesting conditions are not met.  
Translation of foreign currency  
Exchange rate differences arising between the transaction  
date and the reporting date are recognized as Financial  
income or Financial costs.  
Foreign currency transactions are translated into the  
functional currency defined for each company using the  
exchange rates prevailing at the transaction date. Monetary  
items denominated in foreign currencies are translated into  
the functional currency at the exchange rates prevailing at the  
reporting date.  
Financial statements of foreign subsidiaries are translated  
into DKK at the exchange rates prevailing at the reporting  
date for assets and liabilities, and at average exchange rates  
for income statement items.  
The new or amended standards and interpretations are not  
expected to have any significant impact on recognition and  
measurement in the Consolidated financial statements.  
The implementation of IFRS 18 entails a change in the pre-  
sentation of BioPorto's income statement where a change  
in classification of certain items, primarily gains and losses  
from foreign currency translation will be impacted.  
Segment information  
The BioPorto Group does not prepare segment reporting  
internally and therefore only reports one operating segment  
externally. The geographic distribution of revenue and  
revenue from major customers is presented in Note 3 to the  
consolidated financial statements. 75% of non-current assets  
were located in Denmark (50% in 2024).  
49  
BioPorto A/S  
2025 Annual Report  
 
1. Basis of Reporting (continued)  
considers the effects of variable consideration. No element of  
financing is deemed present. Discounts generally arise from  
sales transactions where the customer receives an immediate  
reduction in the selling price. Payment terms are generally  
net 30 days.  
Financial Income and Expenses  
Financial income and expenses include interest, capital gains  
and losses, transactions in foreign currencies, amortization  
of financial assets and liabilities, etc.  
Statements of Profit or  
Loss and Statements of  
Comprehensive Loss  
Income Tax  
Income tax comprises current tax and changes in deferred tax  
for the year. The tax expense/income associated with current  
year results is recognized in the income statement, and the  
tax expense relating to changes is recognized in equity or  
other comprehensive income is recognized in equity.  
To the extent the Group benefits from a deduction in  
the determination of taxable income due to share-based  
compensation, the tax effect of such programs is included  
in income tax.  
Deferred tax assets are reviewed annually and recognized to  
the extent that it is estimated to be probable that they will  
be utilized in the foreseeable future.  
Revenue  
Revenue from contracts with customers comprises sale of  
goods and royalty income. Revenue from the sale of goods  
is recognized at the point in time when control of the goods  
is transferred to the customer, which generally takes place  
upon shipment. Contracts generally do not provide customers  
with a right of return.  
Royalties on net sales is recognized as the underlying  
customers’ sale occurs in accordance with the terms of the  
relevant agreement.  
Production Costs  
Production costs include costs incurred to generate the  
revenue, including direct and indirect costs for raw materials  
and consumables, wages and salaries, freight and packaging  
material, and depreciation of production equipment.  
Sales and Marketing Costs  
Sales and marketing costs include royalties and costs incurred  
for the marketing of goods sold during the year and for  
sales campaigns, etc. This includes costs related to sales and  
marketing staff, advertising, exhibitions and depreciation  
and amortization.  
Revenue from contracts with customers is measured at an  
amount that reflects the consideration to which the Group  
expects to be entitled in exchange for those goods. Amounts  
disclosed as net revenue exclude discounts, VAT and other  
duties.  
Research and Development Costs  
Research and development costs include wages and salaries,  
laboratory materials, patent costs, clinical studies, depreciation  
and amortization, and other costs relating to the Group’s  
research and development activities that are not capitalized.  
The Group considers whether contracts include other  
promises that constitute separate performance obligations  
to which a portion of the transaction price needs to be  
allocated. In determining the transaction price, the Group  
Administrative Costs  
Administrative costs include management and administration,  
including expenses for administrative staff, office premises,  
office expenses, and depreciation and amortization.  
50  
BioPorto A/S  
2025 Annual Report  
 
1. Basis of Reporting (continued)  
The basis of depreciation is cost less expected residual value  
at the end of the useful life. Depreciation methods, useful lives  
and residual values are reassessed annually. To the extent  
that depreciation is not reflected in the cost of inventories  
as production overhead, depreciation is recognized on  
the income statement under production costs, sales and  
marketing costs, research and development costs and  
administrative costs, respectively.  
at the acquisition date without affecting either the profit/  
loss for the year or the taxable income. If the tax base may  
be calculated according to several sets of tax regulations,  
deferred tax is measured in accordance with the regulations  
that apply to the use of the asset or settlement of the liability  
as planned by Management. Deferred tax assets, including the  
tax base of tax loss carry-forwards, are recognized under other  
non-current assets at the expected value of their utilization,  
either as an off-set against tax on future income or as an off-  
set against deferred tax liabilities within the same legal tax  
entity or jurisdiction (joint taxation), cf. Note 9.  
Balance Sheets  
Rights and Software  
Rights and software are measured at cost less accumulated  
depreciation and impairment. Cost comprises the purchase  
price as well as costs directly related to the purchase until  
the date on which the asset is ready for use.  
Assets are depreciated on a straight-line basis over their  
estimated useful lives based on the following assessment  
of the expected lives of the assets:  
Rights and software 3-10 years  
Depreciation is recognized in the income statement under  
sales and marketing costs and administrative costs.  
Right-of-Use Assets  
The Company leases facilities in Hellerup, Denmark. Right-  
of-use assets are initially measured at the amount equal to  
the lease liability, adjusted by the amount of any prepaid or  
accrued lease payments. Lease liabilities are initially measured  
as the net present value of the future lease payments  
discounted by the incremental borrowing rate, cf. Note 13.  
Deferred tax related to the elimination of unrealized intra-  
group profits and losses is adjusted upon consolidation.  
Deferred tax is measured based on the tax regulations and  
rates that, according to the rules in force at the balance sheet  
date, will apply at the time the deferred tax is expected  
to crystallize as current tax. Changes in deferred tax due  
to changes in the tax rate are recognized on the income  
statement.  
Property, Plant, and Equipment  
Property, plant, and equipment are measured at cost  
less accumulated depreciation and impairment losses.  
Cost comprises the purchase price and any costs directly  
attributable to the acquisition until the date when the asset  
is ready for use, cf. Note 12.  
The right-of-use asset is depreciated over the shorter of the  
asset’s useful life or the lease term on a straight-line basis.  
Depreciation is recognized on the income statement under  
administrative costs.  
Impairment of non-current assets  
The carrying amounts of other non-current assets are tested  
annually to determine whether there is any indication of  
impairment. If such an indication exists, the recoverable  
amount of the asset is calculated. The recoverable amount  
is the higher of an asset’s fair value, less expected costs to  
sell and its value in use. An impairment loss is recognized  
when the carrying amount of an asset or a cash generating  
Deferred Tax Assets  
Deferred tax is measured using the balance sheet liability  
method on temporary differences between the carrying  
amount and tax base of assets and liabilities. However, no  
deferred tax is recognized on temporary differences regarding  
non-deductible goodwill or other items for which temporary  
differences, with the exception of acquisitions, have arisen  
Assets are depreciated on a straight-line basis over their  
estimated useful lives based on the following assessment  
of the expected lives of the assets:  
Property, plant, and equipment 3-5 years  
51  
BioPorto A/S  
2025 Annual Report  
 
1. Basis of Reporting (continued)  
unit exceeds the recoverable amount of the asset or the cash  
generating unit. Impairment losses are recognized in the  
income statement as production costs, sales and distribution  
costs or administrative costs. Impairment of assets is reversed  
to the extent changes have occurred to the assumptions and  
estimates leading to the impairment. Impairment is only  
reversed to the extent the new carrying amount of an asset  
does not exceed the carrying amount the asset would have  
had net of depreciation, had the asset not been impaired,  
cf. Note 13.  
execute the sale, considering marketability, obsolescence,  
and expected losses, cf. Note 14.  
current assets are not remeasured due to the Group’s plan  
to sell the assets, and the assets are presented separately.  
Trade Receivables  
Trade receivables are measured at their transaction price,  
less an allowance for lifetime expected credit losses. Trade  
receivables are grouped based on business area and age to  
estimate credit losses. Trade receivables are written off when  
there is no reasonable expectation of recovery. Allowances  
for expected credit losses and write-offs are classified in sales  
and marketing costs, cf. Note 15.  
Cash and Cash Equivalents  
Cash and cash equivalents comprise cash at bank and in hand.  
Issue Costs  
Issue costs include legal fees, placement fees, and other  
costs associated with the issuing of new shares. Issue costs  
associated with the exercise of warrants are recognized in  
equity.  
Inventories  
Inventories are measured at the lower of first-in first-out  
(FIFO) cost or net realizable value. The cost of raw materials  
comprises the purchase price plus delivery costs. The cost of  
work in progress and finished goods comprises the cost of raw  
materials, direct and indirect labor, and production overhead.  
Production overhead comprises indirect material and labor  
costs, maintenance and depreciation of the property, plant  
and equipment used in the manufacturing process, allocations  
of depreciations, utilities and related items, and the cost of  
production management.  
Taxes Receivable  
Current taxes receivable are recognized on the balance sheet  
as calculated tax on the taxable income for the year, adjusted  
for tax on prior yearstaxable income and for tax paid under  
the on-account tax scheme.  
Companies covered by the Danish tax credit scheme  
(Skattekreditordningen) may obtain payment of the base of  
Fair value of warrants granted  
Proceeds received from the exercise of warrants are reflected  
in equity, cf. Note 5.  
Lease Liabilities  
The Group leases office space. Leases are recognized as a  
right-of-use asset and a corresponding liability at the date  
at which the leased asset is available for use by the Group,  
except for low-value assets or short-term assets where the  
lease term is 12 months or less. Short term leases and leases  
of low value are recognized as an expense on a straight-line  
basis over the lease term.  
losses originating from research and development expenses  
subject to a statutory limit of DKK 25 million.  
The net realizable value of inventories is calculated as the  
selling price less costs of conversion and costs incurred to  
Prepayments  
Prepayments are measured at cost. Prepayments comprise  
expenditures that relate to subsequent periods.  
Lease liabilities are initially recognized at the present value  
of future lease payments. Initial recognition of each lease  
is assessed individually to determine the probability of  
exercising any potential extension options. Options to extend  
Assets held for sale  
Disposal groups that do not include any scoped-in non-  
52  
BioPorto A/S  
2025 Annual Report  
 
1. Basis of Reporting (continued)  
a lease term is included in the calculation of the lease liability  
if it is reasonably certain that the extension option will be  
exercised. The lease liability is measured using a discount rate  
equal to the incremental borrowing rate. If a lease contract  
is modified, the lease liability is remeasured.  
Lease costs are accounted for as a single lease component.  
Variable service components invoiced separately are expensed  
as operational costs. These cost are primarily presented in  
Administrative costs in the Income Statement.  
Each lease payment is allocated between the liability and  
financial cost. The financial cost is recognized over the lease  
period to produce a constant periodic rate of interest on the  
remaining balance of the liability for each period, cf. Note 13.  
recognized on the income statement under financial expenses  
over the term of the loan.  
Other liabilities are measured at amortized cost.  
Cash flows from financing activities comprise changes in  
the size or composition of the share capital of BioPorto A/S  
and related costs, the raising of loans, repayment of interest-  
bearing debt, and payment of dividends to shareholders.  
Equity  
Foreign currency translation reserve comprises the share  
of foreign exchange differences arising on translation of  
financial statements of entities that have a functional cur-  
rency other than DKK.  
Cash Flow Statement  
The statement of cash flows, which is compiled using the  
indirect method, shows cash flow from operating, investing,  
and financing activities, and the Group's cash and cash  
equivalents at the beginning and end of the year.  
Cash flows from operating activities are calculated as Loss  
before financial items (EBIT) adjusted for non-cash operating  
items, working capital changes, financial income, financial  
expenses, establishment cost (subsidiaries), and income  
taxes paid and received.  
Cash flows for investing activities comprise acquisitions and  
disposals of intangible assets, property, plant and equipment  
and financial assets.  
Tax Payable  
Current tax payables are recognized on the balance sheet as  
calculated tax on the taxable income for the year, adjusted  
for tax on the prior years’ taxable income and for tax paid  
under the on-account tax scheme.  
Other Financial Liabilities  
Financial liabilities are measured at amortized cost, applying  
the “effective interest rate method, to the extent that the  
difference between the proceeds and the nominal value is  
53  
BioPorto A/S  
2025 Annual Report  
 
1. Basis of Reporting (continued)  
Financial Ratios  
Earnings per share (EPS) and diluted earnings per share (DEPS) are calculated in accordance  
with IAS 33.  
Financial ratios have been calculated in accordance with the guidelines from the Danish  
Society of Financial Analysts. See also “Non-IFRS financial measure.  
The ratios listed in the key figures and ratios section were calculated as follows:  
(Revenue year 1 – Revenue year 0) x 100  
Revenue Growth  
Revenue year 0  
Gross profit x 100  
Gross Margin  
Net revenue  
Equity, closing x 100  
Equity Ratio  
Total liabilities, closing  
Net Asset Value Per  
Capital and reserves, closing  
Share at Year End  
No. of shares, closing  
54  
BioPorto A/S  
2025 Annual Report  
 
2. Significant Accounting Estimates and Judgements  
The calculation of the carrying amounts of certain assets and liabilities requires an estimate  
of how future events will affect the value of such assets and liabilities at the balance sheet  
date. Estimates material to financial reporting are made in the calculation of, inter alia,  
development costs, incentive schemes, right-of-use assets, inventories, accounts receivable,  
and deferred taxes.  
Estimates are updated on an ongoing basis by the Group’s management and are based on  
past experience, other known factors, and the occurrence of future events that are reasonably  
expected to take place. Special care is used in this area in view of the high level of uncertainty  
that characterizes the macroeconomic context.  
The main items affected by estimates are reviewed below.  
The estimates made are based on assumptions that Management finds reasonable given the  
circumstances, but which are inherently uncertain and unpredictable. The assumptions may  
be incomplete or imprecise and unexpected events or circumstances may arise. In addition,  
the Company is subject to risks and uncertainties that may cause actual results to deviate  
from the estimates. Such estimates comprise judgements made on the basis of the most  
recent information available at the reporting date. It may be necessary to change previous  
estimates as a result of changes to the assumptions on which the estimates were based or  
due to supplementary information, additional experience, or subsequent events.  
Write-down for Inventory Obsolescence  
The write-down for inventory obsolescence reflects management’s estimates of the Group’s  
loss expectations, determined on the basis of past experience and historical and projected  
trends for the related items. Cf. Note 14.  
Warrant Plans  
The measurement of warrant plans at fair value requires the formulation of specific assumptions,  
the most significant of which include the value of the underlying shares on the valuation date  
and the expected volatility of the price/value of the underlying shares. Cf. Note 5.  
Similarly, the value of assets and liabilities often depends on future events that are uncertain.  
In that connection, it is necessary to set out e.g., a course of events that reflects Management’s  
assessment of the probable course of events.  
The preparation of financial statements in accordance with IFRS requires the use of estimates  
for some material amounts. In addition, the Group’s management is required to make  
judgements and assumptions as to how the Group’s accounting policies should be applied  
in certain areas.  
The process of drafting financial statements involves the use of estimates and assumptions,  
and the application of judgement, about future events. These estimates represent the  
Company’s assessment on the date of the financial statements. However, because of their  
very nature, each of these factors could produce material changes in balance sheet amounts  
in future years.  
55  
BioPorto A/S  
2025 Annual Report  
 
3. Business Area Reporting  
In 2025, US represented 10% or more of BioPorto’s revenue (DKK 24.2 million).  
In 2024, US represented 10% or more of BioPorto’s revenue (DKK 20.6 million).  
In 2025, one customer represented 10% or more of BioPorto’s revenue (DKK 5.1 million).  
In 2024, one customer represented 10% or more of BioPorto’s revenue (DKK 3.7 million).  
56  
BioPorto A/S  
2025 Annual Report  
GEOGRAPHIC DISTRIBUTION  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
North America  
24,178  
20,634  
Denmark, and rest of Europe  
12,227  
10,237  
Asia  
3,882  
5,372  
Total  
40,287  
36,243  
PRODUCT GROUPS  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
NGAL tests  
28,224  
23,054  
Antibody  
10,535  
10,783  
ELISA kits  
1,380  
2,269  
Royalty and other revenue  
148  
137  
Total  
40,287  
36,243  
 
4. Staff Costs  
(1) Reflects amounts to board members including the tax equalization scheme.  
(2) The remuneration for the Board of Directors and Executive Management is further described in the Remuneration  
Report for 2025.  
(3) Bonus consists of annual cash bonus.  
The table above includes expensed remuneration for Executive Management, while they are in executive positions at  
BioPorto. Any remuneration received by former Executive Management after stepping down from their executive position  
is excluded from the table. Termination payments to the former CEO amounts to DKK 4.9 million. Please refer to the Remu-  
neration Report for 2025 for further description.  
57  
BioPorto A/S  
2025 Annual Report  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Wages and salaries  
61,231  
52,741  
Defined contribution pension plans  
2,808  
2,396  
Share-based compensation expenses  
(637)  
(875)  
Other social security costs  
3,767  
3,659  
Other staff costs  
1,351  
757  
Total staff costs  
68,520  
58,678  
Average number of employees  
46  
38  
SPECIFICATION OF STAFF COSTS  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Production costs  
6,410  
5,500  
Sales and marketing costs  
16,319  
16,229  
Research and development costs  
18,097  
19,121  
Administrative costs  
27,694  
17,828  
Total staff costs  
68,520  
58,678  
REMUNERATION FOR KEY  
MANAGEMENT PERSONNEL  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Board of Directors(2)  
Remuneration(1)  
2,028  
1,970  
Share-based compensation expenses  
1,287  
174  
Board of Directors, Total  
3,315  
2,144  
Executive Management(2)  
Salary  
8,980  
6,960  
Bonus(3)  
1,048  
378  
Contribution based pension  
428  
218  
Other employee benefits
130  
187  
Remuneration, total  
10,586  
7,743  
Share-based compensation expenses  
1,045  
2,005  
Executive Management, Total  
11,631  
9,748  
Remuneration for Key Management Personal  
14,946  
11,892  
 
5. Share-Based Compensation  
For the purpose of motivating and retaining Management and key staff and aligning their  
interests with those of its shareholders, BioPorto A/S uses warrants as an incentive scheme.  
The arrangements, which are exercised by the issuance of new shares (equity-settled share-  
based payment transaction), entitle the recipient to subscribe for new shares in the parent  
Company at a price defined on the date of grant.  
For the years ended December 31, 2025 and December 31, 2024, share-based compensation  
totaled a recovery of DKK 0.6 million and DKK 0.9 million, respectively. These number of  
warrants reflect the impact of DK 8.9 million and DKK 15.3 million, respectively, of non-cash  
equity compensation recoveries related to forfeited warrants. The Board established warrant  
programs in 2025 pursuant to the authorization in section 18a of the Articles of Association.  
Each warrant granted in 2025 vests over a two to four-year service period, includes conditions  
on claw-back in case of e.g., erroneous financial information and provisions on accelerated  
vesting in case of e.g., a takeover bid and/or business combinations, other performance-based  
metrics and provides the holder the right to subscribe for one share in BioPorto:  
Detailed terms of the new and existing warrants, including applicable vesting schedules,  
can be found in the Articles of Association on our website. At the end of 2025, a total of  
13,581,250 warrants were outstanding, corresponding to 2.7% of the issued and outstanding  
nominal capital stock. Warrant terms are included in the Company’s Articles of Association,  
which can be found at www.bioporto.com. Upon vesting, each warrant entitles the recipient  
to subscribe for one share in BioPorto A/S.  
58  
BioPorto A/S  
2025 Annual Report  
OVERVIEW OF EXERCISE PERIODS  
February 2021  
February 11, 2023 to February 10, 2026  
December 2021  
December 28, 2022 to September 28, 2026  
May 2022  
May 5, 2023 to May 5, 2027  
December 2022  
December 8, 2023 to December 8, 2027  
February 2023  
February 16, 2024 to February 16, 2028  
September 2023  
September 22, 2023 to September 22, 2033  
April 2024  
April 23, 2024 to April 22, 2034  
November 2024  
November 4, 2024 to August 4, 2029  
April 2025  
April 28, 2025 to April 28, 2035  
June 2025  
June 12, 2025 to June 12, 2030  
September 2025  
September 1, 2025 to September 1, 2030  
 
Warrant Program  
The Board established warrant programs in 2025 for the purpose of creating  
a long-term incentive for retaining and motivating Management and  
employees in accordance with the Company’s remuneration policy and  
the authorization in section 18a of the Articles of Association. Each warrant  
granted in 2025 (as listed below) includes conditions on claw-back in case  
of e.g., erroneous financial information and provisions on accelerated  
vesting in case of e.g., a takeover bid and/or business combinations,  
and provides the holder the right to subscribe for one share in BioPorto:  
Detailed terms of the new and existing warrants, including applicable vesting schedules,  
can be found in the Articles of Association on the Company's website. At the end of 2025,  
a total of 13,518,250 warrants were outstanding, corresponding to 2.7% of the issued and  
outstanding nominal capital stock.  
September 1, 2025  
On September 1, 2025, the Board of Directors of BioPorto A/S issued 5,000,000 warrants for  
the subscription of an equal number of shares to a new member of Executive Management.  
The exercise price was DKK 1.28 per share, corresponding to the closing price on Nasdaq  
Copenhagen on September 1, 2025. The theoretical market value of the newly issued  
warrants is DKK 2,506,734. The calculation is based on the Black-Scholes formula using an  
interest rate of 1.80% and the historical volatility of BioPorto A/S’s shares over 36 months  
calculated to 56.40%. Half of the warrants vest over a 4-year period, and the remaining  
half upon achievement of certain KPIs tied to the Company’s revenue performance in the  
period 2025-2028. The warrants include conditions on claw-back in case of e.g., erroneous  
financial information and provisions on accelerated vesting in case of e.g., a takeover bid  
and/or business combinations. Warrants may only be exercised within the authorized  
trading window as listed in the Articles of Association. There are not any specific exercise  
conditions to be met for exercising, besides from it to be in the trading window. The  
warrant program has a exercise period of 5 years.  
June 12, 2025  
On June 12, 2025, the Board of Directors of BioPorto A/S issued 3,250,000 warrants for the  
subscription of an equal number of shares to the Senior Leadership Team. The exercise  
price was DKK 1.39 per share, corresponding to the closing price on Nasdaq Copenhagen  
on June 12, 2025. The theoretical market value of the newly issued warrants is DKK  
1,823,986 based on the Black-Scholes formula using an interest rate of 1.76% and the  
historical volatility of BioPorto A/S’s shares over 36 months calculated to 58.49%. Half  
of the warrants vest over a 4-year period, and the remaining half upon achievement of  
certain KPIs tied to the Company’s revenue performance in the period 2025-2028. The  
warrants include conditions on claw-back in case of e.g., erroneous financial information  
and provisions on accelerated vesting in case of e.g., a takeover bid and/or business  
combinations. Warrants may only be exercised within the authorized trading window as  
listed in the Articles of Association. There are not any specific exercise conditions to be  
met for exercising, besides from it to be in the trading window. The warrant program has  
a exercise period of 5 years.  
April 28, 2025  
On April 28, 2025, the Board of Directors of BioPorto A/S issued 1,700,000 warrants for  
the subscription of an equal number of shares to members of the Board of Directors.  
The exercise price was DKK 1.5 per share corresponding the closing price on Nasdaq  
Copenhagen on April 28, 2025. The theoretical market value of the issued warrants was  
DKK 1,843,580 based on the Black-Scholes formula using an interest rate of 2.37% and the  
historical volatility of BioPorto A/S's shares of 36 months calculated to 63.82%. Warrants  
vest in equal tranches on a quarterly basis over a 2-year period. Warrants may only be  
exercised within the authorized trading window as listed in the Articles of Association.  
There are not any specific exercise conditions to be met for exercising, besides from it to  
be in the trading window. The warrant program has a exercise period of 10 years.  
View the Articles of Association for warrant details in-  
cluding vesting schedules  
59  
BioPorto A/S  
2025 Annual Report  
 
Warrant Program (Continued)  
November 4, 2024  
On November 4, 2024, the Board of Directors of BioPorto A/S issued 2,000,000 warrants for  
the subscription of an equal number of shares to a new member Executive Management.  
The exercise price was DKK 1.89 per share, corresponding to the closing price on Nasdaq  
Copenhagen on November 4, 2024. The theoretical market value of the newly issued  
warrants is DKK 1,681,601. The calculation is based on the Black-Scholes formula using an  
interest rate of 1.86% and the historical volatility of BioPorto A/S’s shares over 36 months  
calculated to 65.41%. Half of the warrants vest over a 4-year period, and the remaining half  
upon achievement of certain KPIs tied to the Company’s revenue performance in the  
period 2024-2027. The warrants include conditions on claw-back in case of e.g., erroneous  
financial information and provisions on accelerated vesting in case of e.g., a takeover bid  
and/or business combinations. Warrants may only be exercised within the authorized  
trading window as listed in the Articles of Association. There are not any specific exercise  
conditions to be met for exercising, besides from it to be in the trading window. The  
warrant program has a exercise period of 5 years.  
April 23, 2024  
On April 23, 2024, the Board of Directors of BioPorto A/S issued 4,000,000 warrants for  
the subscription of an equal number of shares to members of Executive Management.  
The exercise price was DKK 1.23 per share corresponding the closing price on Nasdaq  
Copenhagen on April 23, 2024. The theoretical market value of the issued warrants was  
DKK 2,218,694 based on the Black-Scholes formula using an interest rate of 3.15% and  
the historical volatility of BioPorto A/S's shares of 36 months calculated to 64.52%. Half  
of the warrants vest over a 2-year period, and the remaining half upon completion of a  
qualified capital raise in the Company with terms of qualification (including timing and  
amount of proceeds) as defined by the Board of Directors. Warrants may only be exercised  
within the authorized trading window as listed in the Articles of Association. There are  
not any specific exercise conditions to be met for exercising, besides from it to be in the  
trading window. The warrant program has a exercise period of 10 years.  
September 22, 2023  
On September 22, 2023, the Board of Directors of BioPorto A/S issued a total of 700,000  
warrants to members of the Board of Directors of the Company, and further to issue a  
total of 2,750,000 warrants to employees of the BioPorto group for the subscription of an  
equal number of shares. The exercise price was DKK 1.686 per share, corresponding to  
the closing price on Nasdaq Copenhagen on September 22, 2023. The theoretical market  
value of the newly issued warrants is DKK 1,689,141. The calculation is based on the Black-  
Scholes formula using an interest rate of 3.39% and the historical volatility of BioPorto A/S’  
shares over 15 months calculated to 62.90%. The warrants to the employeesvest twelve  
(12) months after the Company achieves marketing rights from the FDA for its NGAL test  
for pediatric use. Regarding the warrants to the Board of Directors, fifty percent (50%) of  
the Warrants shall vest and become immediately exercisable on the first anniversary of  
the date of the 2023 Annual General Meeting, which is April 27, 2024, and fifty percent  
(50%) of the Warrants shall vest and become immediately exercisable six months after  
shares of the Company (or an entity succeeding the Company) have been admitted to  
trading on a recognized stock exchange, regulated market, multilateral trading facility  
or similar in the United States (whether as a separate or dual listing and/or in the form  
depositary receipts or similar), provided such admission to trading takes place prior to  
December 31, 2028, in each case, subject to the Beneficiary’s continued service as a  
board member in the Company through the date of the Company’s 2024 Annual General  
Meeting expected to be held in the first half of 2025.The warrants include conditions on  
claw-back in case of e.g., erroneous financial information and provisions on accelerated  
vesting in case of e.g., a takeover bid and/or business combinations. The warrants to the  
members of the board are subject to the terms set out in the notice for the annual general  
meeting included in company Announcement no. 5 of April 5, 2023. Warrants may only  
be exercised within the authorized trading window as listed in the Articles of Association.  
There are not any specific exercise conditions to be met for exercising, besides from it  
to be in the trading window. The warrant program has a exercise period of 10 years.  
February 16, 2023  
On February 16, 2023, the Board of Directors of BioPorto A/S issued 500,000 warrants  
for the subscription of an equal number of shares. The exercise price was DKK 2.405 per  
share corresponding the closing price on Nasdaq Copenhagen on 16 February 2023. The  
theoretical market value of the issued warrants was DKK 472,127 based on the Black-  
Scholes formula using an interest rate of 2.81% and the historical volatility of BioPorto A/S'  
60  
BioPorto A/S  
2025 Annual Report  
 
Warrant Program (Continued)  
shares of 26 months calculated to 66.12%. One-fourth of this Stock Option shall vest and  
become exercisable on the first anniversary of the Grant Date and the remaining three-  
quarters of the Stock Option shall vest and become exercisable in twelve equal tranches,  
each tranche vesting per calendar quarter thereafter (i.e., 1 January, 1 April, 1 July and 1  
October, provided that first such tranche shall vest on 1 April 2024), subject to the U.S.  
Grantee’s continued service to the Company or a subsidiary of the Company through the  
applicable vesting date. The warrants vest over a four-year period. Warrants may only be  
exercised within the authorized trading window as listed in the Articles of Association.  
There are not any specific exercise conditions to be met for exercising, besides from it to  
be in the trading window. The warrant program has a exercise period of 5 years.  
December 8, 2022  
On December 8, 2022, the Board of Directors of BioPorto A/S issued 1,200,000 warrants  
for the subscription of an equal number of shares. The exercise price was DKK 2.55 per  
share, corresponding to the closing price on Nasdaq Copenhagen on December 8, 2022.  
The theoretical market value of the newly issued warrants is DKK 1,316,500 based on  
the Black-Scholes formula using an interest rate of 2.11% and the historical volatility  
of BioPorto A/S’ shares over 27 months calculated to 73.07%. Warrants may only be  
exercised within the authorized trading window as listed in the Articles of Association.  
There are not any specific exercise conditions to be met for exercising, besides from  
it to be in the trading window. The warrant program has a exercise period of 5 years.  
May 5, 2022  
On May 5, 2022, the Board of Directors of BioPorto A/S issued 270,000 warrants for the  
subscription of an equal number of shares. The exercise price was DKK 1.28 per share  
corresponding the closing price on Nasdaq Copenhagen on May 5, 2022. The theoretical  
market value of the issued warrants was DKK 149,000 based on the Black-Scholes formula  
using an interest rate of 0.50% and the historical volatility of BioPorto A/S' shares of 27  
months calculated to 75.37%. Warrants may only be exercised within the authorized  
trading window as listed in the Articles of Association. There are not any specific exercise  
conditions to be met for exercising, besides from it to be in the trading window. The  
warrant program has a exercise period of 5 years.  
December 31, 2021  
On December 31, 2021, the Board of Directors of BioPorto A/S issued 12,600,000 warrants  
for the subscription of an equal number of shares. The exercise price was DKK 2.47 per  
share corresponding the closing price on Nasdaq Copenhagen on December 30, 2021. The  
theoretical market value of the issued warrants was DKK 12,685,000 based on the Black-  
Scholes formula using an interest rate of -0.58% and the historical volatility of BioPorto  
A/S' shares of 27 months calculated to 72.12%. One-fourth of the Warrants shall vest on  
the first anniversary of the Date of Grant and the remaining three-quarters of the Warrants  
shall vest in twelve equal tranches, each tranche vesting per calendar quarter thereafter  
(i.e. 1 January, 1 April, 1 July and 1 October, provided first tranche shall vest on 1 April  
2023), subject to the Beneficiary’s continued service to the Company or a subsidiary of  
the Company through the applicable vesting date. Notwithstanding the above vesting  
terms, the Stock Option shall vest and become immediately exercisable upon the Company  
achieving marketing rights from the U.S. Food and Drug Admninistration for The NGAL Test  
for pediatric use. Warrants may only be exercised within the authorized trading window  
as listed in the Articles of Association. There are not any specific exercise conditions to  
be met for exercising, besides from it to be in the trading window. The warrant program  
has a exercise period of 5 years.  
February 10, 2021  
On February 10, 2021, the Board of Directors of BioPorto A/S issued 350,000 warrants  
for the subscription of an equal number of shares. The exercise price was DKK 6.11 per  
share corresponding the closing price on Nasdaq Copenhagen on February 10, 2021.  
The theoretical market value of the issued warrants was DKK 714,560 based on the Black-  
Scholes formula using an interest rate of -0.58% and the historical volatility of BioPorto  
A/S' shares of 24 months calculated to 61.79%. Warrants may only be exercised within  
the authorized trading window as listed in the Articles of Association. There are not any  
specific exercise conditions to be met for exercising, besides from it to be in the trading  
window. The warrant program has a exercise period of 5 years.  
61  
BioPorto A/S  
2025 Annual Report  
 
62  
BioPorto A/S  
2025 Annual Report  
Overview of 2025 Warrant Activity  
Exercise  
Outstanding at  
Exercisable at  
WARRANTS OVERVIEW 2025  
Price  
January 1  
Granted  
Expired  
Forfeited  
Reclassified  
December 31  
December 31  
February 2021  
6.11  
350,000  
-
-
-
-
350,000  
350,000  
December 2021  
2.47  
1,000,000  
-
-
-
-
1,000,000  
1,000,000  
May 2022  
1.28  
270,000  
-
-
(270,000)  
-
-
-
December 2022  
2.55  
1,200,000  
-
-
(1,200,000)  
-
-
-
February 2023  
2.41  
500,000  
-
-
(500,000)  
-
-
-
September 2023  
1.69  
3,250,000  
-
-
(500,000)  
-
2,750,000  
2,500,000  
April 2024  
1.23  
4,000,000  
-
-
(3,000,000)  
-
1,000,000  
875,000  
November 2024  
1.89  
2,000,000  
-
-
(1,687,500)  
-
312,500  
250,000  
April 2025  
1.50  
-
1,700,000  
-
-
-
1,700,000  
425,000  
June 2025  
1.39  
3,250,000  
-
-
(1,156,250)  
-
2,093,750  
-
September 2025  
1.28  
5,000,000  
-
-
(625,000)  
-
4,375,000  
-
Total  
12,570,000  
9,950,000  
-
(8,938,750)  
-
13,581,250  
5,400,000  
Weighted Average Exercise Price  
1.967  
1.427  
-
1.761  
-
1.706  
2.098  
Outstanding at  
Exercisable at  
WARRANTS OVERVIEW 2025  
January 1  
Granted  
Expired  
Forfeited  
Reclassified  
December 31  
December 31  
Board of Directors  
500,000  
1,700,000  
-
-
(500,000)  
1,700,000  
675,000  
Executive Management  
6,250,000  
7,000,000  
-
(6,312,500)  
-
6,937,500  
1,375,000  
Management  
5,570,000  
1,250,000  
-
(2,626,250)  
150,000  
4,343,750  
3,250,000  
Other employees  
250,000  
-
-
-
(250,000)  
-
-
Previous employees  
-
-
-
-
600,000  
600,000  
100,000  
Total  
12,570,000  
9,950,000  
-
(8,938,750)  
-
13,581,250  
5,400,000  
 
63  
BioPorto A/S  
2025 Annual Report  
Overview of 2024 Warrant Activity  
Exercise  
Outstanding at  
Exercisable at  
WARRANTS OVERVIEW 2024  
Price  
January 1  
Granted  
Expired  
Forfeited  
Reclassified  
December 31  
December 31  
August 2019  
1.70  
250,000  
-
(250,000)  
-
-
-
-
February 2021  
6.11  
350,000  
-
-
-
-
350,000  
350,000  
December 2021  
2.47  
6,600,000  
-
-
(5,600,000)  
-
1,000,000  
765,625  
May 2022  
1.28  
270,000  
-
-
-
-
270,000  
168,750  
December 2022  
2.55  
1,200,000  
-
-
-
-
1,200,000  
600,000  
February 2023  
2.41  
500,000  
-
-
-
-
500,000  
250,000  
April 2023  
1.53  
3,604,058  
-
-
(3,604,058)  
-
-
-
September 2023  
1.69  
3,350,000  
-
-
(100,000)  
-
3,250,000  
3,000,000  
April 2024  
1.23  
4,000,000  
-
-
-
4,000,000  
-
1,670,000  
July 2024  
2.14  
6,000,000  
-
-
(6,000,000)  
-
-
-
November 2024  
1.89  
2,000,000  
-
-
-
-
2,000,000  
-
Total  
16,124,058  
12,000,000  
(250,000)  
(15,304,058)  
-
12,570,000  
6,804,375  
Weighted Average Exercise Price  
2.167  
1.905  
-
2.115  
-
1.967  
2.144  
Outstanding at  
Exercisable at  
WARRANTS OVERVIEW 2024  
January 1  
Granted  
Expired  
Forfeited  
Reclassified  
December 31  
December 31  
Board of Directors  
600,000  
-
-
(100,000)  
-
500,000  
250,000  
Executive Management  
9,204,058  
6,000,000  
-
(9,204,058)  
250,000  
6,250,000  
1,920,000  
Management  
5,820,000  
6,000,000  
(250,000)  
(6,000,000)  
5,570,000  
-
4,384,375  
Other employees  
500,000  
-
-
-
(250,000)  
250,000  
250,000  
Total  
16,124,058  
12,000,000  
(250,000)  
(15,304,058)  
-
12,570,000  
6,804,375  
 
All share-based compensation is recognized in the Consolidated Statements of Profit or Loss based on their grant date fair values. Using this model, fair value is calculated based on  
assumptions with respect to (i) the fair value of the Company’s common stock on the grant date; (ii) expected volatility of the Company’s common stock price, (iii) the periods of time over  
which the grantees are expected to hold their warrants prior to exercise (vesting period), (iv) expected dividend yield on the Company’s common stock, and (v) risk-free interest rates.  
The grant date fair value of share options is estimated using the Black-Scholes option valuation model. The fair value of warrants are determined on the date of grant. The expected  
volatility is calculated based on historical data of the Company’s common stock. The expected dividend yield per share is zero as the Company has never paid dividends and does not  
currently anticipate paying any in the foreseeable future. Risk-free interest rates are based on quoted Danish rates for securities with maturities approximating the warrant’s expected  
term. The expected term of warrants granted is determined using the weighted average vesting period of the warrant.  
Stock based compensation is reduced for actual forfeitures in the period in which the forfeiture occurs and generally recognized on a straight-line basis over the service period of the grant.  
64  
BioPorto A/S  
2025 Annual Report  
Specifications of Black-Scholes Model Parameters  
Feb 2021  
Dec 2021  
May 2022  
Dec 2022  
Feb 2023  
Sep 2023  
Apr 2024  
Nov 2024  
Apr 2025  
Jun 2025  
Sep 2025  
Share price at grant (DKK)  
6.11  
2.47  
1.28  
2.55  
2.41  
1.69  
1.23  
1.89  
1.50  
1.39  
1.28  
Expected volatility rate  
61.80%  
72.10%  
75.40%  
73.10%  
66.12%  
62.9%  
66.44%  
62.17%  
63.82%  
58.49%  
56.40%  
Expected vesting period (months)  
24  
27  
27  
27  
35  
27  
23  
47  
24  
48  
48  
Expected dividend yield per share  
-
-
-
-
-
-
-
-
-
-
-
Risk-free interest rate p.a.  
-0.58%  
-0.58%  
-0.50%  
2.11%  
2.81%  
3.39%  
3.15%  
1.86%  
2.37%  
1.76%  
1.80%  
Fair value at grant (DKK thousand)  
715  
12,685  
149  
1,317  
472  
2,588  
2,219  
1,682  
1,844  
1,824  
2,507  
Duration (years)  
5
5
5
5
5
10  
10  
5
10  
5
5
 
6. Amortization and Depreciation  
The following tables reflect the amortization and depreciation of the respective asset class  
and the classification of such expenses in the consolidated statements of profit or loss.  
 
 
7. Auditor Fee  
 
In 2025, the fee for other services provided to the Group by Deloitte Statsautoriseret  
Revisionspartnerselskab amounted to DKK 0.2m (DKK 0.2m), mainly relating to fees for  
review of the Company's Interim reports.  
65  
BioPorto A/S  
2025 Annual Report  
RIGHTS AND SOFTWARE  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Intangible assets  
138  
181  
Total amortization  
138  
181  
Classification of amortization:
Production costs  
0
10  
Sales and marketing costs  
138  
138  
Research and development costs  
0
24  
Administrative costs  
0
9
Total amortization  
138  
181  
PROPERTY, PLANT AND EQUIPMENT  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Property, plant and equipment  
616  
508  
Total depreciation  
616  
508  
Classification of depreciation:
Production costs  
130  
144  
Sales and marketing costs  
37  
107  
Research and development costs  
399  
158  
Administrative costs  
50  
99  
Total depreciation  
616  
508  
RIGHT-OF-USE ASSETS  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Right-of-use assets  
1,754  
1,692  
Total depreciation  
1,754  
1,692  
Classification of depreciation:
Administrative costs  
1,754  
1,692  
Total depreciation  
1,754  
1,692  
BREAKDOWN OF FEES  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Statutory audit  
887  
718  
Tax services  
20  
267  
Other assurance engagements  
50  
30  
Other services  
212  
189  
Total  
1,169  
1,204  
 
8. Financial Income and Expenses  
9. Taxes  
INCOME TAX FOR THE YEAR  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Current tax  
(5,520)  
(5,500)  
Total tax expense for the year  
(5,520)  
(5,500)  
Tax for the year is included in:  
Tax on result for the year  
(5,520)  
(5,500)  
Tax in other comprehensive income  
-
-
Total tax expense for the year  
(5,520)  
(5,500)  
Reconciliation of effective tax rate  
2025  
%
2024  
%
Tax at the Danish tax rate of 22%:  
(19,280)  
22%  
(16,224)  
22%  
Tax effects of:  
Non-deductible expenses  
995  
(1%)  
1,310  
(2%)  
Share-based remuneration  
(136)  
0%  
(153)  
0%  
Deduction for research and development  
(916)  
1%  
(593)  
1%  
Change in valuation of deferred tax assets  
10,292  
(12%)  
11,053  
(15%)  
Prior-year tax adjustments  
3,525  
(4%)  
(893)  
1%  
Total tax expense for the year  
(5,520)  
6%  
(5,500)  
7%  
 
 
66  
BioPorto A/S  
2025 Annual Report  
FINANCIAL INCOME  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Interest income from bank  
511  
1,643  
Interest income from financial assets measured at amor-
tized cost  
511  
1,643  
Net foreign exchange gains  
0
900  
Total financial income  
511  
2,543  
FINANCIAL EXPENSES  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Interest expenses, lease liabilies  
567  
453  
Interest expenses on financial liabilities measured at
amortized cost  
567  
453  
Unrealized foreign exchange loss  
1,089  
-
Realized foreign exchange loss  
193  
-
Other financial expenses  
205  
381  
Total financial expenses  
2,054  
834  
 
9. Taxes (Continued)  
10. Earnings/(Loss) Per Share  
The Group has a deferred tax asset. However, Management has found that it is not sufficiently  
probable that the tax asset can be utilized in the foreseeable future. Therefore, tax assets have  
not been recognized on the balance sheet, cf. Note 1. The tax asset is of indefinite duration.  
The gross value of the tax asset prior to the valuation allowance was DKK 116.1 million as of  
December 31, 2025 (DKK 105.1 million).  
Tax receivable represent refunds anticipated within the next twelve months for payments in  
excess of previous US federal tax liabilities and tax credits held by its Danish entities associated  
with the Company’s investment in research and development.  
BioPorto A/S receives a refundable tax credit for research and development activities which  
is recognized in the consolidated financial statements.  
Warrants outstanding were not included in the calculation of loss per share because the  
effect would have been anti-dilutive.  
67  
BioPorto A/S  
2025 Annual Report  
DEFERRED TAX ASSETS NOT  
Balance at  
Prior-year  
Current-year  
Balance at  
RECOGNIZED  
January 1  
adjustments  
movements  
December 31  
DKK THOUSAND  
Intangible assets  
936  
31  
-
967  
Property, plant and equipment  
1,343  
122  
-
1,465  
Right-of-use assets  
(1,447)  
386  
-
(1,061)  
Current assets  
151  
-
146  
(5)  
Leasing liabilities  
1,465  
-
(338)  
1,127  
Warrants  
3,225  
(755)  
(140)  
2,330  
Tax loss carried forward  
105,124  
(2,219)  
13,211  
116,116  
Total temporary differences  
110,797  
(2,974)  
13,267  
121,090  
Deferred tax assets not recognised in the  
(110,797)  
(551)  
(9,742)  
(121,090)  
balance sheet  
Deferred tax assets/(tax liabilities)  
-
(3,525)  
3,525  
-
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Earnings/(Loss) for the period  
(82,117)  
(68,243)  
BioPorto Group's share of loss  
(82,117)  
(68,243)  
Weighted average number of shares (in thousand)  
537,523  
405,763  
Earnings/(Loss) per share (EPS) basic and diluted, DKK  
(0.15)  
(0.17)  
 
11. Rights and Software  
12. Property, Plant and Equipment  
68  
BioPorto A/S  
2025 Annual Report  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Cost at January 1  
3,069  
3,069  
Additions during the period  
-
-
Cost at end of period  
3,069  
3,069  
Accumulated amortization at January 1  
2,793  
2,612  
Amortization expense during the period  
138  
181  
Accumulated amortization at end of period  
2,931  
2,793  
Carrying amount at end of period  
138  
276  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Cost at January 1  
7,862  
6,091  
Additions during the period  
-
1,718  
Currency adjustments  
(105)  
53  
Cost at end of period  
7,757  
7,862  
Accumulated depreciation at January 1  
5,726  
5,172  
Depreciation expense during the period  
616  
508  
Currency adjustments  
(105)  
46  
Accumulated depreciation at end of period  
6,237  
5,726  
Carrying amount at end of period  
1,520  
2,136  
 
13. Leases  
69  
BioPorto A/S  
2025 Annual Report  
RIGHT-OF-USE ASSETS (PROPERTY)  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Cost at January 1  
16,126  
9,109  
Remeasurements  
-
7,017  
Cost at end of period  
16,126  
16,126  
Accumulated depreciation at January 1  
9,547  
7,855  
Depreciation expense during the period  
1,754  
1,692  
Accumulated depreciation at end of period  
11,301  
9,547  
Carrying amount at end of period  
4,825  
6,579  
LEASE LIABILITIES  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Current  
3,471  
3,344  
Non-current  
4,049  
7,846  
Lease liability end of period  
7,520  
11,190  
LEASE LIABILITIES  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Less than 1 year  
3,471  
3,344  
Between 1 and 5 years  
4,049  
7,846  
More than 5 years  
-
-
Total  
7,520  
11,190  
 
13. Leases
(continued)  
14. Inventories  
LEASE LIABILITIES  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Lease liabilities at January 1  
11,190  
7,250  
New or modifications to lease liabilities  
-
7,017  
Repayments  
(3,798)  
(3,734)  
Cancellation of lease liabilities  
-
-
Interest Expense  
567  
453  
Currency adjustments  
(439)  
204  
Lease liabilities end of period  
7,520  
11,190  
Lease liabilities
Cash effect during the year  
3,798  
3,734  
Lease liabilities
Non-cash effect during the year  
(128)  
(7,674)  
The Company executed a sublease agreement of its office space in Needham, MA, USA in  
November 2023 to reduce its cash infrastructure costs. The estimated savings is DKK 4.3  
million over the next two years and four months. As a result of the sublease, the Company  
has a Lease Receivable Long-Term and Lease Receivable Short Term assets as of December  
31, 2025. During the fourth quarter 2024, the Company remeasured its existing Hellerup  
office lease for the lease extension regarding continued use of the space through the end  
of September 2028.  
Inventories has been written down to the extent it is estimated that the product group  
will not contribute substantially to the Company's future revenue. Inventories with no  
movement the last year are written off and recognized in Production costs.  
70  
BioPorto A/S  
2025 Annual Report  
AMOUNTS RECOGNIZED IN CONDENSED  
CONSOLIDATED STATEMENTS OF PROFIT OR  
LOSS  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Depreciation charge of right-of-use assets  
1,754  
1,692  
Interest expense (included in financial expenses)  
567  
453  
Expense related to short-term leases  
-
-
Total  
2,321  
2,145  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Raw materials  
6,331  
3,330  
Work in Progress  
53  
-
Finished goods  
3,814  
1,879  
Write-down  
(896)  
(622)  
Inventories  
9,249  
4,640  
(Recovery)/write-down recognized in the period  
274  
11  
Cost of materials included in production costs  
4,377  
3,329  
 
15. Receivables  
For receivables that mature within one year after the end of the financial year, the nominal  
value is considered to correspond to the fair value.  
A write-down for bad debts is recognized to reduce the carrying amount of trade receivables  
by the value which is impaired due to risk of loss.  
71  
BioPorto A/S  
2025 Annual Report  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Trade receivables  
9,484  
8,251  
Other receivables  
1,165  
1,368  
Prepayments  
2,292  
2,448  
Write-down for bad debt  
(47)  
(64)  
Total receivables  
12,894  
12,003  
AS OF DECEMBER 31, 2025  
Expected credit  
Trade  
Expected  
DKK thousand  
loss rate  
receivables  
loss  
Total  
Not due  
0.1%  
6,437  
7
6,430  
1 - 30 days overdue  
0.0%  
2,297  
1
2,296  
31 - 60 days overdue  
0.3%  
118  
-
118  
61 - 90 days overdue  
0.0%  
-
-
-
More than 90 days overdue  
6.1%  
632  
38  
594  
As of December 31, 2025  
9,484  
47  
9,437  
AS OF DECEMBER 31, 2024  
Expected credit  
Trade  
Expected  
DKK thousand  
loss rate  
receivables  
loss  
Total  
Not due  
0.4%  
7,347  
27  
7,320  
1 - 30 days overdue  
0.1%  
686  
1
685  
31 - 60 days overdue  
1.6%  
123  
2
121  
61 - 90 days overdue  
0.0%  
-
-
-
More than 90 days overdue  
35.8%  
95  
34  
61  
As of December 31, 2024  
8,251  
64  
8,187  
 
16. Other Accrued Liabilities  
 
17. Share Capital  
As of December 31, 2025, the share capital consists of 495,108,887 shares of DKK 1.00  
each. The share capital has been paid up in full. The shares have not been divided into  
classes and carry no special rights. The company raised in 2025 of DKK thousand 76,855  
less issuance cost of DKK thousand 1,118 for net proceeds of DKK thousand 75,737.  
72  
BioPorto A/S  
2025 Annual Report  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Accrued incentive compensation  
3,343  
3,290  
Accrued vacation  
1,437  
1,599  
Accrued severence costs  
3,420  
0
Accrued expenses - Other  
432  
829  
Total Other Accrued Liabilities  
8,632  
5,718  
* A reclassification of DKK 5.620 million has been made in the 2024 numbers from Other Accrued Liabilities to
Trade Payable to ensure correct presentation.  
 
18. Financial Risks and Financial Instruments  
Financial Assets  
Trade receivables generally fall due within 30 days after the end of the financial year. Their  
carrying amount is assumed to equal fair value. The Lease receivable pertains to amounts  
due from sublease agreement between BioPorto Diagnostics, Inc. with Bone Support, Inc.  
entered November 2023 through lease termination of April 2027.  
Financial Liabilities  
Trade payables generally fall due within one year after the end of the financial year. Their  
carrying amount is assumed to equal fair value.  
73  
BioPorto A/S  
2025 Annual Report  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Trade receivables, net  
9,437  
8,187  
Other receivables  
1,165  
1,368  
Lease receivable - Short term  
1,125  
1,200  
Lease receivable - Long term  
393  
1,707  
Deposits  
1,348  
1,387  
Cash and cash equivalents  
54,893  
59,664  
Financial assets at amortized costs  
68,361  
73,513  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Lease liabilities  
7,520  
11,190  
Trade payables  
14,021  
11,326  
Financial liabilities at amortized costs  
21,541  
22,516  
 
18. Financial Risks and Financial Instruments (continued)  
Currency Risk  
The Group’s presentation currency is DKK, but part of its activities are denominated in  
currencies other than DKK, primarily USD and EUR. Consequently, there is a risk of exchange  
rate fluctuations having an impact on the Group’s reported results.  
The Group is exposed to currency risks through sales, production, R&D contracts, and payroll  
denominated in currencies other than Danish kroner. The Group is subjected to transaction  
risk related to sales and purchases in foreign currencies, and translation risk when translating  
foreign entities into the Group’s presentation currency.  
The Group has determined not to hedge its USD exposure. As the Danish kroner is pegged  
to the EUR, hedging of the Company’s transactions in EUR is not found necessary.  
Foreign exchange sensitivity  
A sensitivity analysis demonstrates the effect on net profit and other comprehensive income  
of a 5% fluctuation in the DKK/USD exchange rate at December 31, 2025, reflecting BioPorto’s  
exposure on that date. The analysis encompasses the impact on the Group’s cash balances,  
trade receivables, prepayments, trade payables, and accrued liabilities. It is based on the  
assumption that the exchange rate shift takes place on the reporting date, with all other  
factors held constant. A increase of 5% in exchange rate would have impact of DKK 1.1 million,  
while a derease in exchange rate would have the opposite effect.  
Interest rate risk  
The Group’s exposure to interest rate risk is considered to be limited. Substantially all of the  
Group’s assets consisted of bank deposits.  
74  
BioPorto A/S  
2025 Annual Report  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Trade receivables  
USD  
19%  
30%  
EUR  
80%  
68%  
Other  
1%  
2%  
Cash and cash equivalents  
DKK  
84%  
93%  
USD  
14%  
6%  
EUR  
2%  
1%  
Trade payables  
DKK  
15%  
53%  
USD  
80%  
29%  
EUR  
5%  
17%  
Other  
0%  
1%  
Revenue  
DKK  
1%  
1%  
USD  
46%  
41%  
EUR  
53%  
58%  
 
18. Financial Risks and Financial  
Instruments (continued)  
19. Commitments and Contingencies  
The Company has a defined contribution 401(k) plan established for its US-based employees  
whereby it makes a non-elective safe harbor contribution of 3% of eligible compensation.  
Contribution expenses totaled DKK 0.5 million for the year ended December 31, 2025 (DKK  
0.5 million).  
All of the Company’s existing and proposed diagnostic products are regulated by the FDA and  
similar regulatory bodies in other countries and/or regions. Most aspects of development,  
production, and marketing, including product testing, authorizations to market, labeling,  
promotion, manufacturing, and record keeping, are subject to regulatory review.  
After marketing or other applicable regulatory approval has been granted for its products,  
the Company must continue to comply with governmental regulations. Failure to comply  
with applicable requirements can lead to sanctions, including withdrawal of products from  
the market, recalls, refusal to authorize government contracts, product seizures, civil money  
penalties, injunctions, and criminal prosecution.  
From time-to-time the Company may become involved in legal proceedings or may be subject  
to claims arising in the ordinary course of its business. Although the results of litigation  
and claims cannot be predicted with certainty, the Company currently believes that the  
final outcome of these ordinary course matters will not have a material adverse effect on  
its business, operating results, financial condition or cash flows. Regardless of the outcome,  
litigation can have an adverse impact on the Company because of defense and settlement  
costs, diversion of management resources, and other factors.  
Credit Risk  
The financial situation and ability of customers to pay trade receivables are regularly evaluated,  
with payment upon placement of an order required if ability-to-pay is evaluated to be low.  
Expected credit losses are estimated by grouping trade receivables by customer type and  
days past due (Cf. Note 15). An estimated loss percentage is calculated based on historical  
credit losses and specific customer circumstances. Trade receivables are written off when  
there is no reasonable expectation of recovery.  
Liquidity Risk  
In connection with BioPorto’s ongoing financing of operations, efforts are made to ensure  
sufficient financial resources are available. This assessment is performed by evaluating cash  
forecasts, monitoring the development of the cash position and operating cash requirements.  
Any potential cash shortfalls are evaluated for raising capital to ensure strategic plans are met  
and debt/equity could be a potential source of cash under the right facts and circumstances.  
BioPorto’s cash and cash equivalents totaled DKK 54.9 million and DKK 59,7million as of December  
31, 2025 and December 31, 2024, respectively, The Company’s current liabilities are due within  
12 months from the reporting date (in this case December 31, 2025). The only long-term liability  
of the Company is its lease obligation. See Note 13 for further information on when this liability  
is due. The liquidity is sufficient to support operations for the year 2026.  
Free funds are placed in bank deposits to maintain flexibility.  
Capital Structure  
The Board of Directors and Management regularly assess whether the Group’s capital structure  
properly serves the interests of the Group and its shareholders.  
75  
BioPorto A/S  
2025 Annual Report  
 
20. Related Parties  
BioPorto Group has no related parties with control over the Group and no related parties with significant influence other than key management  
personnel - mainly in the form of the Board of Directors and Executive Management.  
Board of Directors and Executive Management  
Jens Due Olsen, Chairman of the Board Of Directors (effective April 11, 2025)  
Henrik Juuel, Chairman of the Board of Directors (effective January 31, 2025, resigned effective  
April 11, 2025), Vice-Chairman of the Board of Directors (effective April 11, 2025)  
Donna Haire (effective April 11, 2025)  
Mats Thorén, Board Member  
John McDonough, Chairman of the Board of Directors  
(resigned effective January 31, 2025)  
Don Hardison, Vice-Chairman of the Board of Directors (resigned effective April 11, 2025)  
Dr. Michael Singer, Board Member (resigned effective April 11, 2025)  
Ninfa Saunders, Board Member (resigned effective April 11, 2025)  
Carsten Buhl, Chief Executive Officer (effective September 1, 2025)  
Niels Høy Nielsen, Chief Financial Officer  
Gry Husby Larsen, Chief Legal Officer  
Peter Mørch Eriksen, Chief Executive Officer (resigned effective August 31, 2025)  
Group-Owned Companies  
BioPorto Diagnostics A/S, 2900 Hellerup, Denmark. Ownership: 100%  
BioPorto Diagnostics Inc., Needham, Massachusetts, USA. Ownership: 100%  
BioPorto Inc., Needham, Massachusetts, USA. Ownership: 100%  
Related Party Transactions  
The related party transactions during 2025 were as follows:  
Ordinary management remuneration, Cf. Note 4.  
The related party transactions during 2024 were as follows:  
Ordinary management remuneration, Cf. Note 4.  
The Company paid Michael Singer, a Board Member, the equivalent of DKKt 131 under a consulting agreement.  
76  
BioPorto A/S  
2025 Annual Report  
 
Parent Company Financial Statements  
Profit or Loss Statement  
2025  
2024  
DKK THOUSAND  
Notes  
2
Jan 1-Dec 31  
Jan 1-Dec 31  
Revenue  
9,600  
9,600  
Gross profit  
9,600  
9,600  
Administrative costs  
3
29,070  
25,756  
Loss before financial items (EBIT)  
(19,470)  
(16,156)  
Loss from investments in subsidiaries  
Financial income  
4
5
5
(53,197)  
5,887  
(66,027)  
14,338  
Financial expenses  
(15,337)  
(82,117)  
(398)  
Loss before tax  
(68,243)  
Income tax benefit, net  
6
-
-
Net loss  
(82,117)  
(68,243)  
Proposed distribution of loss  
Accumulated Deficit  
(82,117)  
(68,243)  
77  
BioPorto A/S  
2025 Annual Report  
 
Assets  
Equities and Liabilities  
2025  
2024  
2025  
2024  
DKK THOUSAND  
Notes  
DKK THOUSAND  
Notes  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Non-current assets  
Equity  
Property, plant and equipment and intan-  
gible assets  
Share capital  
495,109  
1,224  
429,670  
(1,052)  
Exchange rate adjustments  
Property, plant and equipment  
-
-
Accumulated other comprehensive  
(loss)/income  
(433,324)  
(360,868)  
Right-of-use assets  
Total property, plant and equipment  
and intangible assets  
4,824  
6,579  
4,824  
6,579  
Total equity  
63,009  
67,750  
Provisions  
Financial assets  
Provisions in subsidiaries  
with negative equity  
Investments in subsidiaries  
Receivables from subsidiaries  
Deposits  
4
4,433  
141,980  
949  
3,164  
121,801  
922  
123,447  
110,317  
Total provisions  
123,447  
110,317  
Total financial assets  
Total non-current assets  
147,362  
152,186  
125,887  
132,466  
Liabilities  
Non-current liabilities  
Lease obligation  
Non-current liabilities  
Current assets  
3,431  
5,121  
Current tax receivable  
Other receivables  
5,500  
576  
5,500  
378  
3,431  
5,121  
Current liabilities  
Cash and cash equivalents  
Total current assets  
43,818  
49,894  
53,669  
59,547  
Current portion of lease obligations  
Joint taxation  
1,690  
5,500  
749  
1,537  
5,500  
936  
Total assets  
202,080  
192,013  
Trade payables  
Other payables  
4,254  
12,193  
852  
Current liabilities  
8,825  
Total liabilities  
15,624  
13,946  
Total equity and liabilities  
202,080  
192,013  
78  
BioPorto A/S  
2025 Annual Report  
 
Foreign currency translation  
Parent Company Statement of Changes in Equity  
AMOUNTS IN DKK THOUSAND  
SHARES IN THOUSANDS  
Foreign curren-  
cy translation  
Share Capital  
Share Premium  
Accumulated Deficit  
Total  
Balance at December 31, 2024  
Net loss  
429,670  
-
-
-
(360,868)  
(82,117)  
-
(1,052)  
-
67,750  
(82,117)  
2,276  
-
-
Other comprehensive loss  
2,276  
Transactions with owners:  
Issuance of Stock  
65,439  
11,416  
(1,118)  
(10,298)  
-
-
-
-
-
-
-
76,855  
(1,118)  
-
Issuance costs  
-
-
-
Transferred to Accumulated Deficit  
Share-based compensation  
10,298  
(637)  
(637)  
Balance at December 31, 2025  
495,109  
-
(433,324)  
1,224  
63,009  
AMOUNTS IN DKK THOUSAND  
SHARES IN THOUSANDS  
Foreign currency  
translation  
Share Capital  
Share Premium  
Accumulated Deficit  
Total  
Balance at December 31, 2023  
Net loss  
379,670  
-
-
-
(319,763)  
(68,243)  
-
225  
-
61,948  
(68,243)  
(1,277)  
-
-
Other comprehensive loss  
(1,277)  
Transactions with owners:  
Issuance of Stock  
50,000  
31,400  
(3,387)  
(28,013)  
-
-
-
-
-
-
-
81,400  
(3,387)  
-
Issuance costs  
-
-
-
Transferred to Accumulated Deficit  
Share-based compensation  
28,013  
(875)  
(875)  
Balance at December 31, 2024  
429,670  
-
(360,868)  
(1,052)  
67,750  
79  
BioPorto A/S  
2025 Annual Report  
 
Parent Company  
Notes to Financial Statements  
value to the extent it is deemed to be irrecoverable. If the negative equity value exceeds the  
receivable, then the remaining amount is recognized as a provision to the extent the company  
has a legal or constructive obligation to cover the negative value.  
1. Basis of Reporting  
The financial statements of the parent company, BioPorto A/S, have been prepared in  
accordance with the provisions of the Danish Financial Statements Act for Reporting class  
D (listed) enterprises.  
Statements of Cash Flows  
As permitted under section 86 (4) of the Danish Financial Statements Act, a statement of  
cash flows for the parent company is not presented, as it is included in the Consolidated  
Statement of Cash Flows.  
The annual report is presented in Danish kroner (DKK), which also is the functional currency  
of the company.  
Taxation  
The parent company is taxed jointly with its domestic subsidiary. The jointly taxed Danish  
enterprises are taxed under the Danish on-account tax scheme. Current tax for jointly-taxed  
companies is recognized in each individual company. All jointly-taxed companies are covered  
by the joint-taxation liability. See disclosures related toDeferred tax assetsandTax payables”  
in the Consolidated Financial Statements and related notes thereto.  
Changes in Accounting Policies  
The accounting policies of the Parent Company are unchanged from the prior year.  
Differences Relative to the Group’s Accounting Policies  
The Parent Company’s accounting policies for recognition and measurement are in accordance  
with the Group’s policies with the exceptions set out below.  
Statements of Profit or Loss  
Income from Investments in Subsidiaries.  
Income from investments in subsidiaries are recognized in the parent company’s income  
statement as the proportional share of the subsidiaries results for year corresponding to the  
Parent Company’s ownership.  
Balance Sheets  
Investments in Subsidiaries.  
Investments in subsidiaries are initialy recognized at cost and subsequently measured under  
the equity method. Subsidiaries with a negative net asset value are recognized at DKK nil,  
and any receivable amount from these companies is written down by the negative net asset  
80  
BioPorto A/S  
2025 Annual Report  
 
Parent Company  
2. Business Area Reporting  
GEOGRAPHICAL DISTRIBUTION  
DKK THOUSAND  
SPECIFICATION OF STAFF COSTS  
DKK THOUSAND  
2025  
2024  
2025  
2024  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Jan 1-Dec 31  
Administrative costs  
18,510  
12,059  
Denmark  
9,600  
9,600  
Staff costs  
18,510  
12,059  
Revenue  
9,600  
9,600  
The sale of services in BioPorto A/S exclusively represents intra-group services. Revenue  
is recognized over time in the accounting period in which the performance obligations  
associated with the services are rendered.  
REMUNERATION FOR KEY MANAGEMENT  
PERSONNEL  
2024  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Board of Directors  
Remuneration  
3. Staff Costs  
2,028  
1,287  
3,315  
1,970  
174  
2025  
2024  
Share-based compensation expenses  
Board of Directors, Total  
2,144  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Wages and salaries  
17,098  
428  
878  
17  
9,593  
218  
2,175  
27  
Executive Management  
Salary  
8,980  
1,048  
428  
6,869  
378  
Defined contribution pension plans  
Share-based compensation expenses  
Other social security costs  
Other staff costs  
Bonus  
Contribution based pension  
Other employee benefits  
Remuneration, total  
Share-based compensation expenses  
218  
130  
182  
89  
46  
10,586  
1,045  
7,647  
2,005  
Staff costs  
18,510  
12,059  
Average number of employees  
3
2
Executive Management, Total  
11,631  
14,946  
9,652  
Remuneration for key management personnel  
11,796  
Reclassification of share-based compensation expenses have been made in 2024. Reference  
is made to note 4 in the Consolidated financial statements.  
81  
BioPorto A/S  
2025 Annual Report  
 
Parent Company  
4. Investments in Subsidiaries  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
List of Subsidiaries  
Cost on January 1  
49,364  
(93)  
49,364  
-
Exchange rate adjustments investments in subsidiaries  
Cost at December 31  
Revaluation on January 1  
49,271  
(598,955)  
(53,197)  
2,276  
49,364  
(531,653)  
(66,027)  
(1,275)  
BioPorto Diagnostics A/S  
2900 Hellerup, Denmark  
Ownership: 100%  
Loss from investments in subsidiaries  
Exchange rate adjustments investments in subsidiaries  
Revaluation on December 31  
(649,876)  
(598,955)  
BioPorto Inc.  
Needham, Massachusetts, USA  
Ownership: 100%  
Value on December 31  
(600,605)  
(549,591)  
Negative value of investments set off  
against receivables from group  
481,591  
123,447  
4,433  
442,438  
110,317  
3,164  
Negative value of investments recognized as a provision  
BioPorto Diagnostics Inc.  
Value on December 31  
Needham, Massachusetts, USA  
A reclassification of DKK 33.2 million between revaluation on January 1, 2024, and Negative value  
of investments set off against receivables from group 2024, has been adjusted due to a historical  
misstatement related in Negative value of investments set off against receivables.  
Ownership: 100%, through BioPorto Inc  
Another reclassification of DKK 5.5 million between Negative value of investments set off against  
receivables from group and Negative value of investments recognized as a provision, has been adjusted  
due to reclass of this to "Joint taxation".  
These reclassifications do not have any profit/loss effect.  
82  
BioPorto A/S  
2025 Annual Report  
 
Parent Company  
5. Financial Income and Expenses  
FINANCIAL INCOME  
6. Taxes  
A deferred tax asset has been calculated. However, Management has concluded that it is not  
sufficiently probable that the tax asset can be utilized in the foreseeable future. Therefore,  
tax assets have not been recognized on the balance sheet. Reference is made to Note 9 in  
the Consolidated Financial Statements.  
2025  
2024  
DKK THOUSAND  
Jan 1-Dec 31  
Jan 1-Dec 31  
Interest income from subsidiaries  
Interest income from bank  
5,619  
268  
-
7,214  
1,334  
5,790  
DEFERRED TAX ASSETS NOT  
RECOGNIZED IN THE BALANCE SHEET  
Exchange rate adjustments, net  
2025  
2024  
Total financial income  
5,887  
14,338  
DKK THOUSAND  
Right-of-use assets  
Leasing liabilities  
Jan 1-Dec 31  
(1,061)  
Jan 1-Dec 31  
(1,447)  
1,465  
1,127  
FINANCIAL EXPENSES  
2025  
2024  
Tax loss carryforwards  
6,123  
846  
DKK THOUSAND  
Jan 1-Dec 31  
358  
Jan 1-Dec 31  
Share-based compensation  
(2,330)  
-
Interest expenses, leasing debt  
Interest expenses, other debt  
Unrealized foreign exchange loss  
138  
260  
-
Deferred tax on December 31, net  
3,859  
864  
24  
14,955  
Through the consolidated tax return, the Parent receives a refundable tax credit for research  
and development activities associated with one of its subsidiaries that is recognized in  
that subsidiary.  
Total financial expenses  
15,350  
398  
83  
BioPorto A/S  
2025 Annual Report  
 
Parent Company  
7. Commitments and Contingencies  
BioPorto A/S has acknowledged that it will finance the operations of its subsidiaries BioPorto  
Diagnostics A/S, BioPorto Inc., and BioPorto Diagnostics Inc. through 2026. The Parent is  
jointly taxed with its Danish subsidiary, and they are jointly liable for any such tax liabilities.  
8. Distribution of This Year’s Result  
The Board of Directors proposes that BioPorto A/S’s loss of DKK 82.1 million for the year ended  
December 31, 2025, be transferred to accumulated deficit.  
9. Other Notes  
Reference is made to Note 7 in BioPorto’s consolidated financial statements with respect to  
auditor fees.  
Reference is made to Note 17 in BioPorto’s consolidated financial statements with respect  
to share capital and treasury shares.  
Reference is made to Note 21 in BioPorto’s consolidated financial statements with respect  
to subsequent events.  
84  
BioPorto A/S  
2025 Annual Report  
 
Other Statements  
& Reports  
Statement by the  
Board of Directors & Management  
86  
87  
Independent Auditors Report  
85  
BioPorto A/S  
2025 Annual Report  
 
Statement by the Board of  
Directors and Management  
and the Parent Company and of the results of the Group and  
2025, identified as BIOPORTO-2025-12-31-1-en.zip, has been  
prepared, in all material respects, in compliance with the ESEF  
Regulation.  
The Board of Directors and Executive Management  
have today considered and approved the Annual  
Report of BioPorto Group and BioProto A/S for the  
period January 1 to December 31, 2025.  
Parent Company operations and consolidated cash flows for  
the financial year January 1 to December 31, 2025.  
In our opinion, Management’s commentary is prepared in  
accordance with relevant laws and regulations, and includes a  
fair review of the development in the operations and financial  
circumstances of the Group and the Parent Company, of the  
results for the year, and of the financial position of the Group  
and the Parent Company in general, as well as a description of  
the principal risks and uncertainties pertaining to the Group  
and the Parent Company.  
We recommend the adoption of the Annual Report at the  
Annual General Meeting.  
The consolidated financial statements have been prepared  
in accordance IFRS Accounting Standards as adopted by the  
EU and additional requirements for listed entities in Denmark.  
The Parent Company Financial Statements are prepared in  
accordance with the Danish Financial Statements Act.  
Hellerup, March 26, 2026  
In our opinion, the Consolidated Financial Statements and the  
Parent Company Financial Statements give a true and fair view  
of the financial position at December 31, 2025, of the Group  
In our opinion, the Annual Report of the Group and the Parent  
Company for the financial year January 1 to December 31,  
Executive Management  
_____________________________ _____________________________ _____________________________  
Carsten Buhl
Chief Executive Officer
Niels Høy Nielsen
Chief Financial Officer
Gry Husby Larsen
Chief Legal Officer
Board of Directors  
______________________________ _____________________________  
_____________________________ _____________________________  
Jens Due Olsen
Chair
Henrik Juuel
Vice Chair
Mats Thorén
Member
Donna Haire
Member
86  
BioPorto A/S  
2025 Annual Report  
 
Independent Auditor's Report
Report on the consolidated nancial statements and the
parent nancial statements
To the shareholders of BioPorto A/S
Furthermore, in our opinion, the parent nancial statements  
give a true and fair view of the Parent’s nancial position at  
31.12.2025, and of the results of its operations for the nancial  
year 01.01.2025 - 31.12.2025 in accordance with the Danish  
Financial Statements Act.  
To the best of our knowledge and belief, we have not provided  
any prohibited non-audit services as referred to in Article 5(1)  
of Regulation (EU) No 537/2014.  
Opinion  
We have audited the consolidated nancial statements and  
the parent nancial statements of BioPorto A/S for  
the nancial year 01.01.2025 - 31.12.2025, which comprise  
the income statement, balance sheet, statement of changes  
in equity and notes, including material accounting policy  
information, for the Group as well as the Parent, and the  
statement of comprehensive income and the cash ow  
statement of the Group. The consolidated nancial statements  
are prepared in accordance with IFRS Accounting Standards  
as adopted by the EU and additional disclosure requirements  
for listed entities in Denmark, and the parent nancial  
statements are prepared in accordance with the Danish  
Financial Statements Act.  
We were appointed auditors of BioPorto A/S for the rst  
time on 23.11.2022 for the nancial year 2022. We have been  
reappointed annually by decision of the general meeting for  
a total contiguous engagement period of 4 years up to and  
including the nancial year 2025.  
Our opinion is consistent with our audit book comments  
issued to the Audit Committee and the Board of Directors.  
Basis for opinion  
We conducted our audit in accordance with International  
Standards on Auditing (ISAs) and the additional requirements  
applicable in Denmark. Our responsibilities under those  
standards and requirements are further described in the  
"Auditor’s responsibilities for the audit of the consolidated  
nancial statements and the parent nancial statements"  
section of this auditor’s report. We are independent of the  
Group in accordance with the International Ethics Standards  
Board for Accountants’ International Code of Ethics for  
Professional Accountants (IESBA Code), as applicable to  
audits of nancial statements of public interest entities, and  
the additional ethical requirements applicable in Denmark  
to audits of nancial statements of public interest entities.  
We have also fullled our other ethical responsibilities in  
accordance with these requirements and the IESBA Code. We  
believe that the audit evidence we have obtained is sufficient  
and appropriate to provide a basis for our opinion.  
Key audit matters  
We have determined that there are no key audit matters to  
communicate in our report.  
Statement on the management commentary  
Management is responsible for the management commentary.  
In our opinion, the consolidated nancial statements give  
a true and fair view of the Group’s nancial position at  
31.12.2025, and of the results of its operations and cash ows  
for the nancial year 01.01.2025 - 31.12.2025 in accordance  
with IFRS Accounting Standards as adopted by the EU and  
additional disclosure requirements for listed entities in  
Denmark.  
Our opinion on the consolidated nancial statements and the  
parent nancial statements does not cover the management  
commentary, and we do not express any form of assurance  
conclusion thereon.  
In connection with our audit of the consolidated nancial  
statements and the parent nancial statements, our  
responsibility is to read the management commentary and,  
87  
BioPorto A/S  
2025 Annual Report  
 
In preparing the consolidated nancial statements and the  
parent nancial statements, Management is responsible for  
assessing the Group’s and the Parent’s ability to continue as  
a going concern, for disclosing, as applicable, matters related  
to going concern, and for using the going concern basis of  
accounting in preparing the consolidated nancial statements  
and the parent nancial statements unless Management  
either intends to liquidate the Group or the Entity or to cease  
operations, or has no realistic alternative but to do so.  
Identify and assess the risks of material misstatement  
of the consolidated nancial statements and the parent  
nancial statements, whether due to fraud or error,  
design and perform audit procedures responsive to those  
risks, and obtain audit evidence that is sufficient and  
appropriate to provide a basis for our opinion. The risk  
of not detecting a material misstatement resulting from  
fraud is higher than for one resulting from error, as fraud  
may involve collusion, forgery, intentional omissions,  
misrepresentations, or the override of internal control.  
in doing so, consider whether the management commentary  
is materially inconsistent with the consolidated nancial  
statements and the parent nancial statements or our  
knowledge obtained in the audit or otherwise appears to be  
materially misstated.  
Moreover, it is our responsibility to consider whether the  
management commentary provides the information required  
by relevant law and regulations.  
Auditor's responsibilities for the audit of the consolidated  
nancial statements and the parent nancial statements  
Our objectives are to obtain reasonable assurance about  
whether the consolidated nancial statements and the  
parent nancial statements as a whole are free from material  
misstatement, whether due to fraud or error, and to issue  
an auditor’s report that includes our opinion. Reasonable  
assurance is a high level of assurance, but is not a guarantee  
that an audit conducted in accordance with ISAs and the  
additional requirements applicable in Denmark will always  
detect a material misstatement when it exists. Misstatements  
can arise from fraud or error and are considered material if,  
individually or in the aggregate, they could reasonably be  
expected to inuence the economic decisions of users taken  
on the basis of these consolidated nancial statements and  
these parent nancial statements.  
Based on the work we have performed, we conclude that  
the management commentary is in accordance with the  
consolidated nancial statements and the parent nancial  
statements and has been prepared in accordance with the  
requirements of the relevant law and regulations. We did  
not identify any material misstatement of the management  
commentary.  
Obtain an understanding of internal control relevant  
to the audit in order to design audit procedures that  
are appropriate in the circumstances, but not for the  
purpose of expressing an opinion on the effectiveness  
of the Group’s and the Parent’s internal control.  
Evaluate the appropriateness of accounting policies used  
and the reasonableness of accounting estimates and  
related disclosures made by Management.  
Management's responsibilities for the consolidated nancial  
statements and the parent nancial statements  
Management is responsible for the preparation of consolidated  
nancial statements that give a true and fair view in accordance  
with IFRS Accounting Standards as adopted by the EU  
and additional disclosure requirements for listed entities  
in Denmark as well as the preparation of parent nancial  
statements that give a true and fair view in accordance with  
the Danish Financial Statements Act, and for such internal  
control as Management determines is necessary to enable the  
preparation of consolidated nancial statements and parent  
nancial statements that are free from material misstatement,  
whether due to fraud or error.  
Conclude on the appropriateness of Management’s use  
of the going concern basis of accounting in preparing  
the consolidated nancial statements and the parent  
nancial statements, and, based on the audit evidence  
As part of an audit conducted in accordance with ISAs and the  
additional requirements applicable in Denmark, we exercise  
professional judgement and maintain professional scepticism  
throughout the audit. We also:  
88  
BioPorto A/S  
2025 Annual Report  
 
obtained, whether a material uncertainty exists related to  
events or conditions that may cast signicant doubt on  
the Group's and the Parent’s ability to continue as a going  
concern. If we conclude that a material uncertainty exists,  
we are required to draw attention in our auditor’s report  
to the related disclosures in the consolidated nancial  
statements and the parent nancial statements or, if such  
disclosures are inadequate, to modify our opinion. Our  
conclusions are based on the audit evidence obtained  
up to the date of our auditor’s report. However, future  
events or conditions may cause the Group and the Entity  
to cease to continue as a going concern.  
group as a basis for forming an opinion on the consolidated  
nancial statements and the parent nancial statements.  
We are responsible for the direction, supervision and  
review of the audit work performed for purposes of the  
group audit. We remain solely responsible for our audit  
opinion.  
Report on compliance with the ESEF Regulation  
As part of our audit of the consolidated nancial statements  
and the parent nancial statements of BioPorto A/S we  
performed procedures to express an opinion on whether the  
annual report for the nancial year 01.01.2025 - 31.12.2025,  
with the le name BIOPORTO-2025-12-31-1-en.zip is prepared,  
in all material respects, in compliance with the Commission  
Delegated Regulation (EU) 2019/815 on the European  
Single Electronic Format (ESEF Regulation), which includes  
requirements related to the preparation of the annual report in  
XHTML format and iXBRL tagging of the consolidated nancial  
statements including notes.  
We communicate with those charged with governance  
regarding, among other matters, the planned scope and  
timing of the audit and signicant audit ndings, including  
any signicant deciencies in internal control that we identify  
during our audit.  
Evaluate the overall presentation, structure and content  
of the consolidated nancial statements and the parent  
nancial statements, including the disclosures in the notes,  
and whether the consolidated nancial statements and  
the parent nancial statements represent the underlying  
transactions and events in a manner that gives a true  
and fair view.  
We also provide those charged with governance with  
a statement that we have complied with relevant ethical  
requirements regarding independence, and to communicate  
with them all relationships and other matters that may  
reasonably be thought to bear on our independence, and,  
where applicable, safeguards put in place and measures taken  
to eliminate threats.  
Management is responsible for preparing an annual report  
that complies with the ESEF Regulation. This responsibility  
includes:  
The preparing of the annual report in XHTML format;  
The selection and application of appropriate iXBRL  
tags, including extensions to the ESEF taxonomy and  
the anchoring thereof to elements in the taxonomy,  
for nancial information required to be tagged using  
judgement where necessary;  
Plan and perform the group audit to obtain sufficient  
appropriate audit evidence regarding the nancial  
information of the entities or business units within the  
From the matters communicated with those charged with  
governance, we determine those matters that were of  
most signicance in the audit of the consolidated nancial  
statements and the parent nancial statements of the current  
period and are therefore the key audit matters. We describe  
these matters in our auditor’s report unless law or regulation  
precludes public disclosure about the matter.  
Ensuring consistency between iXBRL tagged data and the  
consolidated nancial statements presented in human  
readable format; and  
89  
BioPorto A/S  
2025 Annual Report  
 
For such internal control as Management determines  
necessary to enable the preparation of an annual report  
that is compliant with the ESEF Regulation.  
Reconciling the iXBRL tagged data with the audited  
consolidated nancial statements.  
Our responsibility is to obtain reasonable assurance on  
whether the annual report is prepared, in all material respects,  
in compliance with the ESEF Regulation based on the evidence  
we have obtained, and to issue a report that includes our  
opinion. The nature, timing and extent of procedures selected  
depend on the auditor’s judgement, including the assessment  
of the risks of material departures from the requirements set  
out in the ESEF Regulation, whether due to fraud or error. The  
procedures include:  
In our opinion, the annual report of BioPorto A/S for the  
nancial year 01.01.2025 - 31.12.2025, with the le name  
BIOPORTO-2025-12-31-1-en.zip, is prepared, in all material  
respects, in compliance with the ESEF Regulation.  
Copenhagen, 26 March 2026
Testing whether the annual report is prepared in XHTML  
format;  
Obtaining an understanding of the company’s iXBRL  
tagging process and of internal control over the tagging  
process;  
Deloitte
Statsautoriseret Revisionspartnerselskab
CVR No. 33963556
Evaluating the completeness of the iXBRL tagging of the  
consolidated nancial statements including notes;  
Kåre Kansonen Valtersdorf
State Authorised Public Accountant
Identification No (MNE) mne34490
Lars Hansen
State Authorised Public Accountant
Identification No (MNE) mne24828
Evaluating the appropriateness of the company’s use of  
iXBRL elements selected from the ESEF taxonomy and  
the creation of extension elements where no suitable  
element in the ESEF taxonomy has been identied;  
Evaluating the use of anchoring of extension elements  
to elements in the ESEF taxonomy; and  
90  
BioPorto A/S  
2025 Annual Report  
 
Forward-looking safe harbor  
statements  
This Annual Report contains forward-looking statements that involve risks, uncertainties,  
and other factors, many of which are outside of BioPorto’s control, that could cause  
actual results to differ materially from the results or expectations discussed in the  
forward-looking statements. Forward-looking statements include statements  
concerning the Group’s plans, objectives, goals, future events, performance and/  
or other information that is not historical information. The words “believe, “expect,  
“anticipate, intend” and “plan” and similar expressions identify forward looking  
statements. Actual results or performance may differ materially from any future results  
or performance expressed or implied by such statements. The important factors that  
could cause our actual results or performance to differ materially include, among  
others, risks associated with product discovery and development, uncertainties related  
to regulatory approval, uncertainties related to the outcome and conduct of clinical  
trials including unforeseen safety issues, uncertainties related to instrument expansion,  
uncertainties related to product manufacturing, the lack of market acceptance of our  
products, our inability to manage growth, the competitive environment in relation  
to our business area and markets, our inability to attract and retain suitably qualified  
personnel, the unenforceability or lack of protection of our patents and proprietary  
rights, our relationships with affiliated entities, changes and developments in technology  
which may render our products obsolete, and other factors, such as the geopolitical  
world situation. For a further discussion of these risks, please refer to the sectionRisk  
Management”in this Annual Report. All such forward-looking statements are expressly  
qualified by these cautionary statements and any other cautionary statements which  
may accompany the forward-looking statements. BioPorto does not undertake any  
obligation to update or revise forward looking statements in this Annual Report  
nor to confirm such statements in relation to actual results, subsequent events, or  
circumstances after the date made.  
91  
BioPorto A/S  
2025 Annual Report  
 
About BioPorto  
BioPor to
Group has facilities in  
Copenhagen, Denmark and Boston,  
MA, USA. The shares of BioPorto A/S are  
listed on the Nasdaq Copenhagen stock  
exchange.  
BioPorto is an in vitro diagnostics company  
focused on saving lives and improving the  
quality of life with actionable biomarkers – tools  
designed to help clinicians make changes in  
patient management.  
BioPorto A/S  
The Company uses its expertise in antibodies and assay development,  
as well as its platform for assay development, to create a pipeline  
of novel and compelling products that focus on conditions where  
there is significant unmet medical need, and where the Company’s  
tests can help improve clinical and economic outcomes for patients,  
providers, and the healthcare ecosystem.  
Tuborg Havnevej 15, ground floor  
DK-2900 Hellerup  
Denmark  
CVR DK-17500317  
The Company’s flagship products are based on the NGAL biomarker  
and designed to aid in the risk assessment and diagnosis of Acute  
Kidney Injury, a common clinical syndrome that can have severe  
consequences, including significant morbidity and mortality, if not  
identified and treated early. With the aid of NGAL levels, physicians  
can identify patients potentially at risk of AKI more rapidly than is  
possible with current standard of care measurements, enabling  
earlier intervention and more tailored patient management  
strategies. The Company markets NGAL tests under applicable  
registrations including CE mark in several countries worldwide.  
Email Investor Relations  
investor@bioporto.com  
Investor Relations Key Info  
bioporto.com/investor-relations/