Shareholder letter
The year 2021 was a volatile market environment for all involved in biotechnology investing, including BB Biotech. The biotech and pharmaceutical sector adapted to the SARS-CoV-2 virus pandemic cycling through Delta and now Omicron variants with offers of booster vaccines, therapeutic antibodies and most recently new antiviral drugs. For human health overall, new modalities such as genetic medicines, cell-based therapies and RNA-based drugs continue to make positive strides and are expected to improve the prognosis of severe and chronic diseases in the coming years.
Dear Shareholders
During the last quarter of the year major global equity indices extended their 2021 gains. Many markets achieved new all-time highs even though SARS-CoV-2 infection rates reaccelerated in the last weeks of 2021 due to the rapid spread of the Omicron variant. The Dow Jones (+21.0% in USD), the Dax (+15.8% in EUR), and the SPI (+23.4% in CHF) indices all showed gains for the year in line with the technology dominated Nasdaq Composite (+22.2% in USD). The Nasdaq Biotech Index (NBI) traded flat for the year (0.0% in USD), lagging the broader markets.
Although the SARS-CoV-2 pandemic remained a dominant topic for healthcare authorities in 2021, an impressive array of drug approvals was reported by the US FDA – total drug approvals comprised 50 NDAs and 10 BLAs (vaccines, blood and cell products) for the year. Additionally, multiple SARS-CoV-2 diagnostic tests, vaccines and drugs were granted emergency use authorization (EUA) by the FDA during 2021.
For 2021, BB Biotech’s total share return of +8.3% in CHF and +13.3% in EUR trended like European equity indices, better than the biotech indices and deviating from the underlying portfolio performance. Strengthening of the USD versus the CHF and EUR throughout the year created modest support for CHF and EUR-denominated performance. The portfolio Net Asset Value (NAV) declined 11.5% in CHF, 7.8% in EUR and 14.2% in USD for 2021.
For the fourth quarter, BB Biotech’s share price declined 8.3% in CHF and 4.7% in EUR. BB Biotech shares proved more resilient than the smaller and mid cap driven correction in the portfolio. BB Biotech’s Net Asset Value (NAV) decreased 14.2% in CHF, 10.9% in EUR and 12.5% in USD, while the NBI index decline of 6.9% in USD for the same period.
The consolidated fourth quarter 2021 data for BB Biotech indicates a net loss of CHF 546 mn versus the 2020 fourth quarter net gain of CHF 665 mn. The consolidated full year 2021 data showed a net loss of CHF 405 mn compared to a net gain of CHF 691 mn for 2020.
Proposed expansion of the Board of Directors of BB Biotech
On the background of an increasingly challenging environment for the biotechnology industry BB Biotech is extremely happy to nominate Dr. Pearl Huang, CEO of Cygnal Therapeutics, and Dr. Laura Hamill, former Executive Vice President Worldwide Commercial Operations for Gilead, for election to the Board of Directors of
A proposed dividend of CHF 3.85 per share
Dividend 2022
CHF 3.85
(Proposed)
The Board of Directors will propose a regular dividend of CHF 3.85 per share at the AGM on March 17, 2022. Applied to the average share price of December 2021 and consistent with the dividend policy introduced in 2013, and corresponding to a 5% dividend yield.
Portfolio adjustments in the fourth quarter 2021
During the fourth quarter, the investment team made no new investments but focused on careful adjustments of existing portfolio positions. Smaller additions to existing portfolio positions were undertaken in the fourth quarter in oncology-focused companies including Relay Therapeutics, Macrogenics and Fate Therapeutics. Similarly, further shares were acquired in commercial (Neurocrine and Myovant) and in genetic medicines companies (Wave Life Sciences, Generation Bio and Ionis). Some share profits were taken in Intra-Cellular with the FDA’s approval for Caplyta to treat bipolar disorder patients. Moderna’s valuation experienced significant volatility in the last quarter 2021, as investors analyzed different scenarios for the Omicron variant. The investment team took advantage of these swings with short-term trading activity, realizing further profits. Altogether, additional investments combined with a declining equity base led to an increase in the BB Biotech investment level by around 4% compared to the third quarter, ending 2021 at 111%.
During the fourth quarter, the investment team made no new investments but focused on careful adjustments of existing portfolio positions.
Fourth-quarter portfolio update
The fourth quarter 2021 provided multiple major milestones for our portfolio holdings such as clinical results, regulatory decisions and licensing deals. With the Omicron variant being highly transmissible but less harmful than previous SARS-CoV-2 variants, and the mRNA vaccine boosters providing good protection against Omicron, the focus for investors regarding pipeline updates has shifted back towards chronic and severe diseases.
Outlook for 2022 with exciting sector fundamentals and anticipated M&A activities
We believe that 2022 will include the continued global vaccination strategies to fight the spread of SARS-CoV-2 variants, including Omicron. Expectations that Omicron could be the «final» severe variant may prove to be premature. With the vaccine and drug industry able to adapt quickly, companies such as Moderna are expected to remain responsive to current and future variants, while at the same time widening their focus on longer term pipeline strategies beyond COVID-19.
We continue to strive for a balanced portfolio between more established mid cap companies and technology leading earlier stage companies.
We continue to strive for a balanced portfolio between more established mid cap companies and technology leading earlier stage companies. It anticipates that the industry will continue to deliver significant progress for both. Product launches such as Vyvgart from Argenx for the treatment of gMG patients or Caplyta from Intra-Cellular for the treatment of bipolar disorder patients will be yardsticks not only for these companies but for the sector as a whole. For development stage companies, managing the vast number of clinical trials will continue to be a challenge in the current COVID-19-restricted environment. BB Biotech’s exposure to oncology development stage companies will be geared towards many clinical trial read-outs during 2022.
With smaller and mid cap company valuations substantially lower than one year ago, we see compelling re-entry opportunities. Similarly, the more established mid cap portfolio companies such as Neurocrine, Incyte and Ionis own attractive assets and technology, which can trigger renewed interest from new investors – or from strategic partners as M&A targets.
Clinical candidates based on new technologies such as genetic medicines are making progress. Crispr Therapeutics together with its development partner Vertex are planning a regulatory submission by late 2022 for CTX001 to treat beta thalassemia and sickle cell patients. Thus, an ex vivo gene editing product could become available as early as 2023 – reviving investors’ interest in the field. Other RNA targeting medicines will be launched in the next 12 to 24 months including products from Alnylam and Ionis. As always, investors will weigh potential implications from US government policymakers associated with midterm elections in late 2022.
Our long-term horizon and structure enables careful investment that does not follow broad market opinions. The highly specialized investment team at BB Biotech believes that the growth case for biotechnology and valuations for portfolio companies are both compelling. We anticipate that following two years dominated by SARS-CoV-2 headlines, 2022 will include advance of the industry to the severe and chronic diseases that continue to demand perennial progress and looks forward to more exciting news flow from our portfolio companies.
We thank you for the trust you have placed in the Company.
The Board of Directors of BB Biotech AG
Dr. Erich Hunziker
Chairman
Dr. Clive Meanwell
Prof. Dr. Mads Krogsgaard Thomsen
Dr. Thomas von Planta
Consolidated balance sheet as at December 31
| in CHF 1 000 | Notes | 2021 | 2020 | |||
| Current assets | ||||||
| Cash and cash equivalents |
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| Receivables from brokers |
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| Securities | 4 |
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| Other assets |
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| Total assets |
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| Current liabilities | ||||||
| Short-term borrowings from banks | 5 |
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| Payables to brokers |
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| Other short-term liabilities | 6 |
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| Tax liabilities |
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| Total liabilities |
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| Shareholders' equity | ||||||
| Share capital | 7 |
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| Treasury shares | 7 | ( |
( |
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| Retained earnings | 7 |
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| Total liabilities and shareholders' equity |
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| Net asset value per share in CHF |
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The notes are an integral part of the consolidated financial statements.
The consolidated financial statements were approved by the Board of Directors of BB Biotech AG on February 15, 2022.
Consolidated statement of comprehensive income for the year ended December 31
| in CHF 1 000 | Notes | 2021 | 2020 | |||
| Operating income | ||||||
| Net gains from securities | 4 |
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| Interest income |
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| Dividend income |
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| Other income |
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| Operating expenses | ||||||
| Net losses from securities | 4 | ( |
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| Finance expenses | ( |
( |
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| Foreign exchange losses | ( |
( |
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| Administrative expenses | 8 | ( |
( |
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| Other expenses | 9 | ( |
( |
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| ( |
( |
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| Profit/(loss) before tax | 12 | ( |
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| Income taxes | 10 | ( |
( |
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| Profit/(loss) for the period | ( |
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| Total comprehensive profit/(loss) for the period | ( |
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| Earnings/(loss) per share in CHF | 11 | ( |
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| Diluted earnings/(loss) per share in CHF | 11 | ( |
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The notes are an integral part of the consolidated financial statements.
Consolidated statement of changes in equity for the year ended December 31
| in CHF 1 000 | Share capital | Treasury shares | Retained earnings | Total | ||||
| Balances at January 1, 2020 |
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| Dividend |
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( |
( |
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| Trade with treasury shares (incl. change in balance) |
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( |
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( |
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| Total comprehensive income for the year |
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| Balances at December 31, 2020 |
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( |
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| Balances at January 1, 2021 |
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( |
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| Dividend |
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( |
( |
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| Trade with treasury shares (incl. change in balance) |
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( |
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| Total comprehensive income for the year |
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( |
( |
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| Balances at December 31, 2021 |
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( |
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The notes are an integral part of the consolidated financial statements.
Consolidated statement of cash flow for the year ended December 31
| in CHF 1 000 | Notes | 2021 | 2020 | |||
| Cash flows from operating activities | ||||||
| Proceeds from sales of securities | 4 |
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| Purchase of securities | 4 | ( |
( |
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| Dividend receipts |
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| Interest receipts |
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| Payments for services | ( |
( |
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| Income taxes paid | ( |
( |
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| Total cash flows from operating activities | ( |
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| Cash flows from financing activities | ||||||
| Dividend | ( |
( |
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| Proceeds from sales of treasury shares | 7 |
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| Purchase of treasury shares | 7 | ( |
( |
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| Borrowing/(repayment) of bank loans | 5 |
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( |
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| Interest payments | ( |
( |
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| Total cash flows from financing activities |
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( |
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| Foreign exchange difference | ( |
( |
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| Change in cash and cash equivalents | ( |
( |
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| Cash and cash equivalents at the beginning of the year |
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| Cash and cash equivalents at the end of the year |
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The notes are an integral part of the consolidated financial statements.
Notes to the consolidated financial statements
1. The Company and its principal activity
BB Biotech AG (the Company) is listed on the SIX Swiss Exchange, in the «Prime Standard Segment» of the German Exchange as well as in the «Star Segment» of the Italian Exchange and has its registered office in
|
Company |
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Capital in CHF 1 000 |
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Capital and voting interest in % |
|
Biotech Focus N.V., Curaçao |
|
11 |
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100 |
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Biotech Growth N.V., Curaçao |
|
11 |
|
100 |
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Biotech Invest N.V., Curaçao |
|
11 |
|
100 |
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Biotech Target N.V., Curaçao |
|
11 |
|
100 |
2. Accounting policies
General
The consolidated financial statements of the Company and its subsidiary companies (the Group) have been prepared in accordance with International Financial Reporting Standards (IFRS), as well as the provisions of the rules of the SIX Swiss Exchange for Investment Companies for the period January 1, 2021, until December 31, 2021. The consolidation is prepared from the financial statements of the Group companies using uniform accounting principles. With the exception of financial assets and liabilities (incl. derivative instruments), which are held at fair value through profit or loss, the financial statements are prepared under the historical cost convention. This requires management to make assumptions and estimates that have an impact on the balance sheet values and items of the income statement in the current financial year. In certain circumstances, the actual values may differ from these estimates.
No new standards, interpretations and amendments to published standards, which are applicable to the Group and valid since January 1, 2021, have been applied in these consolidated financial statements.
The following amended standards were approved, but will only be applicable for the Group prospectively and were not early adopted in these annual consolidated financial statements:
- IAS 1 (amended, effective January 1, 2022) – Classification of Liabilities as Current or Non-current
- IFRS 3 (amended, effective January 1, 2022) – Reference to the Conceptual Framework
- IAS 37 (amended, effective January 1, 2022) – Onerous Contracts – Cost of fulfilling a Contract
- Annual Improvements to IFRS Standards 2018-2020 (effective January 1, 2022) – IFRS 9, IFRS 16
The Group assessed the potential impact of the above-mentioned amended standards. Based on the analysis, the Group concludes that these amended standards have no material impact on the Group’s accounting policies and overall results and financial position.
Basis of consolidation
The consolidated financial statements include the Company and the subsidiary companies which are controlled by it. An investor controls an investee when it is exposed, or has rights, to variable returns from its involvement with the investee and has the ability to affect those returns through its power over the investee. Subsidiaries are fully consolidated from the date on which control is transferred to the Company and are deconsolidated from the date that control ceases. The consolidation is performed using the acquisition method. All intercompany transactions and balances with companies included in the consolidation are eliminated. All Group companies have a December 31 year-end.
Foreign currency translation
Based on the economic environment (primary listing, investors, costs and performance measurement) in which the Company and its subsidiaries operate, the consolidated financial statements of the Group are presented in Swiss francs, which is the Company’s and its subsidiaries functional currency. Transactions in foreign currencies are converted at exchange rates as at transaction dates. Assets and liabilities in foreign currencies at year-end are translated at rates of exchange prevailing as at the balance sheet date. Exchange differences are reflected in the statement of income. Translation differences on marketable securities held at fair value through profit or loss are reported as part of the net gains/(losses) from securities.
The following exchange rates have been used for the preparation of these consolidated financial statements:
|
Currency |
|
31.12.2021 |
|
31.12.2020 |
|
USD |
|
0.91290 |
|
0.88520 |
|
ANG |
|
0.51287 |
|
0.49730 |
|
EUR |
|
1.03740 |
|
1.08134 |
Financial assets
The Group classifies its financial assets in the following categories:
- Financial assets at amortized cost
- Financial assets at fair value through profit or loss
Financial assets at amortized cost
Financial assets at amortized cost are non-derivative financial assets with fixed or determinable payments that are not quoted in an active market. They are generally financial assets held as part of a business model to collect contractual cash flows that are solely payments of interest and principal on the principal outstanding. They are included in current assets, except when they have maturities of greater than twelve months after the balance sheet date. Otherwise they are classified as non-current assets.
Cash and cash equivalents
Cash and cash equivalents comprise current accounts and call money at banks which have a maturity of three months or less.
Receivables from brokers
Receivables from brokers result from security transactions and do not bear any interest.
These amounts are recognized initially at fair value and subsequently measured at amortized cost. At each reporting date, the Group shall measure the loss allowance on amounts due from broker at an amount equal to the Lifetime Expected Credit Loss («ECL») if the credit risk has increased significantly since initial recognition. If, at the reporting date, the credit risk has not increased significantly since initial recognition, the Group shall measure the loss allowance at an amount equal to 12-month ECLs. A significant increase in credit risk is defined as any contractual payment which is more than 30 days past due. Any contractual payment which is more than 90 days past due is considered credit impaired. For receivables from brokers which settle within 10 business days the ECL estimate is nil.
Financial assets at fair value through profit or loss
Financial assets at fair value through profit or loss comprise marketable and non-marketable securities which are classified as current assets.
Initially, securities and derivatives are measured at fair value and are subsequently remeasured at market values based on stock exchange prices or generally accepted valuation models that are based on market conditions existing at each balance sheet date, such as Black- Scholes, earnings multiple and discounted cash flow model. Purchases and sales of securities are accounted for at trade date. Realized gains and losses on security trading are recognized in the statement of comprehensive income as net gains/losses from securities at the day of the transaction. Changes in fair value of securities are also recognized as net gains/losses from securities in the statement of comprehensive income in the same period in which they arise. Securities are derecognized when the rights to receive cash flows from securities have expired or where the Group has transferred substantially all risks and rewards of ownership.
Transaction costs are costs to acquire financial assets at fair value through profit or loss. They include transfer taxes and duties as well as fees and commissions paid to agents, advisers, brokers and dealers. Transaction costs, when incurred, are immediately recognized as an expense.
Financial liabilities
Financial liabilities are generally classified and subsequently measured at amortized cost using the effective interest method, except for financial liabilities held for trading and derivatives.
Payables to brokers
Payables to brokers result from security transactions and do not bear any interest.
Short-term borrowings from banks
Short-term borrowings are recognized initially at fair value, net of transaction costs incurred. Borrowings are subsequently stated at amortized cost; any difference between the proceeds (net of transaction costs) and the redemption value is recognized in the income statement over the period of the borrowings using the effective interest method. Borrowings are classified as current liabilities unless the Group has an unconditional right to defer settlement of the liability for at least twelve months after the balance sheet date.
Income taxes
Current income taxes are calculated on the basis of the applicable tax laws in individual countries and recognized as an expense in the period in which the related profits are made.
Assets or liabilities related to current income taxes are reported in the balance sheet in the items «Current tax assets» or «Current tax liabilities ». Tax effects arising from temporary differences between the carrying amounts of assets and liabilities in the Group’s balance sheet and their corresponding tax values are recognized, respectively, as «Deferred tax assets» and «Deferred tax liabilities». Deferred tax assets arising from temporary differences and from loss carry-forwards eligible for offset are capitalized if it is likely that sufficient taxable profits will be available against which those temporary differences or loss carry-forwards can be offset. Deferred tax assets and deferred tax liabilities are calculated at the tax rates expected to apply in the period in which the tax assets will be realized, or the tax liabilities settled.
Earnings per share
Basic earnings per share are calculated by dividing the net profit/loss attributable to shareholders by the weighted average number of registered shares in issue during the year, less treasury shares. For the diluted earnings per share, the weighted average number of registered shares in issue and the net profit is adjusted to assume conversion of all dilution potential registered shares.
Treasury shares
The company can buy and sell treasury shares in accordance with the Company’s article of association, Swiss company law and in compliance with the listing rules of SIX Swiss Exchange.
Treasury shares are recorded as a deduction from the shareholders’ equity at the amount of considerations paid («Total cost»). All gains and losses arising from trading in treasury shares are directly credited/debited to retained earnings. The FIFO (first in/first out) method is used for derecognition. The purchase price is booked gross with transaction costs. Treasury shares may be acquired and held by the Company or by other members of the consolidated Group.
Net asset value per share
The net asset value per share is calculated by dividing the shareholders’ equity by the number of shares outstanding less treasury shares held at year end.
Dividend income
Dividends on securities are recognized in the income statement when the Group’s right to receive payment is established.
Leasing contracts
The Group has two rental contracts for office space in Schaffhausen and Curacao. Due to the immateriality of a right-of-use-asset and a lease liability, no disclosure according to IFRS 16 are made within these consolidated financial statements.
Pension liability
BB Biotech AG maintains for its employee a defined benefit plan. There is no pension plan for employees of Group companies. Due to the immateriality of any potential pension liability or potential pension asset, no disclosures according to IAS 19 are made within these consolidated financial statements.
Segment reporting
IFRS 8 requires entities to define operating segments and segment performance in the financial statements based on information used by the chief operating decision-maker. The investment manager is considered to be the chief operating decision-maker. An operating segment is a group of assets and operations engaged in providing products or services that are subject to risks and returns that are different from those of other operating segments. The sole operating segment of the Group is investing in companies active in the biotechnology industry. The investment manager works as a team for the entire portfolio, asset allocation is based on a single, integrated investment strategy and the Group’s performance is evaluated on an overall basis. Thus the results published in this report correspond to the sole operating segment of investing in companies active in the biotechnology industry.
Related party
Related parties are individuals and companies where the individual or company has the ability, directly or indirectly, to control the other party or to exercise significant influence over the other party in making financial and operating decisions.
Commitments, contingencies and other off-balance sheet transactions
The operations of the Group are affected by legislative, fiscal and regulatory developments for which provisions are made where a legal or constructive obligation has been incurred which will probably lead to an outflow of resources that can be reasonably estimated.
Critical accounting estimates and judgments
The fair value of financial instruments that are not traded in an active market is determined by using valuation techniques. The Group makes estimates and assumptions that are mainly based on market conditions to value these financial instruments. Since these financial instruments are not traded in an active market, inherent difficulties exist to value these financial instruments. These difficulties cannot be eliminated. The difference between the proceeds from sale of these financial instruments and the carrying amount may be material.
The Company has assessed whether it is appropriate under IFRS 10 to consolidate the Subsidiaries. IFRS 10 states that an investor controls the investee if, and only if, the investor has all of the following:
- Power over the investee;
- Exposure, or rights, to variable returns from its involvement with the investee; and
- The ability to use its power over the investee to affect the amount of the investor’s returns
The Company owns 100% of the capital and voting interest in all four subsidiaries as disclosed in note 1. Therefore the Company has power over the organization and directs the investment activities and dividend policy of its subsidiaries. The scope of the investment management and administration agreement with the investment manager also includes all subsidiaries.
Further, IFRS 10 requires that a subsidiary that provides services related to the parent’s investment activities should not be consolidated if the subsidiary itself is an investment entity. The Company also made an assessment as to whether the Company’s Subsidiaries meet the definition of an investment entity. IFRS 10 provides that an investment entity should have the following typical characteristics:
- It has more than one investment;
- It has more than one investor;
- It has investors that are not related parties of the entity; and
- It has ownership interests in the form of equity or similar interests.
An investment entity is still required to consolidate its subsidiaries if the subsidiary provides services that relate to the investment entity’s investment activities.
The Company concluded that the Subsidiaries do not qualify as investment entities, but are effectively operating subsidiaries as they act as an extension of the Company. They provide requisite investment-related services to the Company and incur costs in doing so, thus the Company consolidates its ssubsidiaries. Fair value accounting would not have a material impact on the net income and equity of the Group.
3. Financial risk management
Within the framework of the law, articles of incorporation and regulations, the investment manager carries out currency and security forward transactions, buys, sells and makes use of options as well as fulfills all necessary obligations that result from these businesses.
Credit risk
The Group is exposed to credit risk, which is the risk that a counterparty will be unable to pay amount in full when due. The Group measures credit risk and expected credit losses using probability of default, exposure at default and loss given default. The Group considers both historical analysis and forward looking information in determining any expected credit loss.
The Group manages and controls its credit risk by maintaining business relations only with counterparties with an acceptable credit rating. All transactions in securities are settled/paid for upon delivery using approved brokers. The risk of default is considered minimal, as delivery of securities sold is only made once the broker has received payment. Payment is made on a purchase once the securities have been received by the broker. The trade will fail if either party fails to meet its obligation. The Group’s credit positions, if any, are monitored on a daily basis by the investment manager and are reviewed on a regular basis by the Board of Directors.
As at December 31, 2021 and 2020, the ECL-impairment model did not have a material impact as (i) the majority of the financial assets are measured at fair value through profit or loss and the impairment requirements do not apply to such instruments; and (ii) the financial assets at amortized cost are short-term (no longer than 10 days). As a result, no loss allowance has been recognized.
Market risks
Risk associated with changing market prices
Due to its business activity and the resulting high portion of securities in relation to total assets, the Group is exposed to market price risk arising from uncertainties and fluctuations on the financial and foreign exchange markets.
The Group participates occassionaly, but to a substantial extent, in the capital of its investments. In the case of sales of large parts of these investments, it may be able to influence the market price. The Group’s securities positions are monitored on a daily basis by the investment manager and are reviewed on a regular basis by the Board of Directors.
The Group’s business is to invest in biotechnology companies with the aim of asset growth. Consequently, it is exposed to market risks of this industry. The individual securities are disclosed in note 4 and the valuation is made at fair value. Consequently, any price changes are reflected accordingly by the changes in fair value in the context of the subsequent valuation.
The annual volatility of registered shares BB Biotech AG (reference volatility for the marketable securities) for 2021 is 22.73% (2020: 33.78%). At December 31, 2021, had the value of listed securities increased or decreased by 22.73% (2020: 33.78%) with all other variables held constant, the increase or decrease respectively in net income/loss as well as shareholders’ equity would amount to CHF 827.1 mn (2020: CHF 1 335.2 mn).
At December 31, 2021 and 2020 the Company holds no unlisted shares.
Interest risk
Interest rates on liquid funds are based on market rates. The funds are due on demand.
Short-term borrowings from banks are on current and short-term loan accounts with interest, based at market rates. Due to the high level of own funds, the effect of interest payable on the statement of income is insignificant. The majority of the Group’s securities are non-interest bearing; as a result, the Group is not subject to significant amounts of risk due to fluctuations in the prevailing levels of market interest rates.
The Group’s interest sensitivity is monitored on a daily basis by the investment manager and reviewed on a regular basis by the Board of Directors.
Currency risk
The Group hold assets denominated in currencies other than the Swiss franc, the functional currency. They are therefore exposed to currency risk, as the value of the securities denominated in other currencies will fluctuate due to changes in exchange rates. Depending on the market situation the Group could use foreign currency options and/or forward contracts to reduce the currency risk.
The following table summarizes the Group’s exposure to currency risks:
|
2021 |
|
Net exposure 31.12. (in CHF 1 000) |
|
Annual volatility (in %) |
|
Potential impact (in CHF 1 000) 1) |
|
USD |
|
3 642 324 |
|
6.46 |
|
235 185 |
|
ANG |
|
128 |
|
6.46 |
|
8 |
|
|
|
|
|
|
|
|
|
2020 |
|
|
|
|
|
|
|
USD |
|
3 952 760 |
|
7.41 |
|
292 741 |
|
ANG |
|
7 |
|
7.41 |
|
1 |
1 Potential impact on total comprehensive income as well as shareholders' equity with all other variables held constant
The Group’s currency position is monitored on a daily basis by the investment manager and is reviewed on a regular basis by the Board of Directors.
Liquidity risk
The Group invests the majority of its assets in investments that are traded in an active market and can be readily disposed of. The Group’s treasury shares, with the exception of shares purchased under a share buy-back program, are considered readily realizable as they are listed on three stock exchanges. The Group can invest a minor part of its portfolio in securities, which are not traded on a stock exchange and may be illiquid. As a result, the Group may not be able to liquidate its investments in these instruments on short notice. In addition, the Group has access to a credit line (notes 5 and 13).
The tables below analyze the Group’s financial liabilities into relevant maturity groupings based on the period between the balance sheet date and the contractual maturity date (in CHF 1 000):
|
At December 31, 2021 |
|
Less than 1 month |
|
1–3 months |
|
More than 3 months / no stated maturity |
|
Short-term borrowings from banks |
|
355 000 |
|
– |
|
– |
|
Other short-term liabilities |
|
4 737 |
|
694 |
|
– |
|
Total liabilities |
|
359 737 |
|
694 |
|
– |
|
|
|
|
|
|
|
|
|
At December 31, 2020 |
|
|
|
|
|
|
|
Short-term borrowings from banks |
|
63 000 |
|
– |
|
– |
|
Payables to brokers |
|
6 576 |
|
– |
|
– |
|
Other short-term liabilities |
|
5 313 |
|
396 |
|
– |
|
Total liabilities |
|
74 889 |
|
396 |
|
– |
The Group’s liquidity position is monitored on a daily basis by the investment manager and is reviewed on a regular basis by the Board of Directors.
Diversification
The investment portfolio usually consists of 20 to 35 investments. This includes five to eight large core investments, defined as positions > 5%. These investments together will account for up to two-thirds of the portfolio. Companies without a stock market listing shall not exceed 10% of the portfolio.
As at December 31, 2021, the Group held seven core investments, representing 50% (2020: five core investments, 35%) of the portfolio. The portfolio is – in line with the strategy – concentrated on a limited number of investments. Risk diversification is therefore limited.
Fair values
The following table presents the Group’s assets that are measured at fair value at December 31 (in CHF 1 000):
|
2021 |
|
Level 1 |
|
Level 2 |
|
Level 3 |
|
Total |
|
Assets |
|
|
|
|
|
|
|
|
|
Securities |
|
|
|
|
|
|
|
|
|
– Shares |
|
3 638 890 |
|
– |
|
– |
|
3 638 890 |
|
– Derivative instruments |
|
– |
|
– |
|
2 222 |
|
2 222 |
|
Total assets |
|
3 638 890 |
|
– |
|
2 222 |
|
3 641 112 |
|
|
|
|
|
|
|
|
|
|
|
2020 |
|
|
|
|
|
|
|
|
|
Assets |
|
|
|
|
|
|
|
|
|
Securities |
|
|
|
|
|
|
|
|
|
– Shares |
|
3 952 504 |
|
– |
|
– |
|
3 952 504 |
|
– Derivative instruments |
|
– |
|
– |
|
2 155 |
|
2 155 |
|
Total assets |
|
3 952 504 |
|
– |
|
2 155 |
|
3 954 659 |
The fair value of financial instruments traded in active markets is based on quoted market prices at the balance sheet date. A market is regarded as active if quoted prices are readily and regularly available and those prices represent actual and regularly occurring market transactions on an arm’s length basis. The quoted market price used for financial assets held by the Group is the closing price. These instruments are included in level 1.
The fair value of financial instruments that are not traded in an active market is determined by using valuation techniques. These valuation techniques maximize the use of observable market data where it is available. The options are valued on the basis of the Black-Scholes model which is based on market conditions existing at each balance sheet date. These instruments are included in level 2.
If one or more of the significant inputs is not based on observable market data, the instrument is included in level 3. The valuation of level 3 instruments is quarterly reviewed. As soon as new or adjusted parameters are available the valuation model (e.g. earnings multiple model) of unlisted shares is adjusted accordingly. As of December 31, 2021, the Company holds one level 3 instrument, allocated as part of a corporate action on October 24, 2019 (December 31, 2020: identical).
The table below summarizes the transactions in level 3 instruments (in CHF 1 000):
|
|
|
2021 |
|
2020 |
|
Opening balance |
|
2 155 |
|
2 355 |
|
Purchases/Sales/Reclassification |
|
– |
|
– |
|
Gains/(losses) included in net gain/loss from securities |
|
67 |
|
(201) |
|
Closing balance |
|
2 222 |
|
2 155 |
|
Gains/(losses) on level 3 instruments included in net gain/loss from securities |
|
67 |
|
(201) |
There have been no transfers between level 1, 2 and 3 during the reporting period. No sensitivity analysis has been disclosed due to the immaterial amount of level 3 instruments.
For assets and liabilities carried at amortized cost, their carrying values are a reasonable approximation of fair value.
4. Financial assets
Securities
The changes in value of securities by investment category are as follows (in CHF 1 000):
|
|
|
Listed shares |
|
Unlisted shares |
|
Derivative instruments |
|
Total |
|
Opening balance as at 01.01.2020 at fair values |
|
3 518 985 |
|
– |
|
4 685 |
|
3 523 670 |
|
Purchases |
|
699 570 |
|
– |
|
– |
|
699 570 |
|
Sales |
|
(1 010 092) |
|
– |
|
– |
|
(1 010 092) |
|
Net gains/(losses) from securities |
|
744 042 |
|
– |
|
(2 531) |
|
741 511 |
|
Realized gains |
|
364 618 |
|
– |
|
– |
|
364 618 |
|
Realized losses |
|
(83 963) |
|
– |
|
– |
|
(83 963) |
|
Unrealized gains |
|
882 536 |
|
– |
|
– |
|
882 536 |
|
Unrealized losses |
|
(419 149) |
|
– |
|
(2 531) |
|
(421 680) |
|
Closing balance as at 31.12.2020 at fair values |
|
3 952 504 |
|
– |
|
2 155 |
|
3 954 659 |
|
|
|
|
|
|
|
|
|
|
|
Opening balance as at 01.01.2021 at fair values |
|
3 952 504 |
|
– |
|
2 155 |
|
3 954 659 |
|
Purchases |
|
955 515 |
|
– |
|
– |
|
955 515 |
|
Sales |
|
(925 467) |
|
– |
|
– |
|
(925 467) |
|
Net gains/(losses) from securities |
|
(343 662) |
|
– |
|
67 |
|
(343 595) |
|
Realized gains |
|
312 779 |
|
– |
|
– |
|
312 779 |
|
Realized losses |
|
(1 831) |
|
– |
|
(2 330) |
|
(4 161) |
|
Unrealized gains |
|
437 584 |
|
– |
|
67 |
|
437 651 |
|
Unrealized losses |
|
(1 092 194) |
|
– |
|
2 330 |
|
(1 089 864) |
|
Closing balance as at 31.12.2021 at fair values |
|
3 638 890 |
|
– |
|
2 222 |
|
3 641 112 |
Securities comprise the following:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Company |
|
Number 31.12.2020 |
|
Change |
|
Number 31.12.2021 |
|
Market price in original currency 31.12.2021 |
|
Valuation CHF mn 31.12.2021 |
|
Valuation CHF mn 31.12.2020 |
||
|
Moderna |
|
2 854 963 |
|
(1 191 614) |
|
1 663 349 |
|
USD |
|
253.98 |
|
385.7 |
|
264.0 |
|
Argenx SE |
|
921 332 |
|
49 206 |
|
970 538 |
|
USD |
|
350.19 |
|
310.3 |
|
239.8 |
|
Ionis Pharmaceuticals |
|
8 220 000 |
|
2 012 973 |
|
10 232 973 |
|
USD |
|
30.43 |
|
284.3 |
|
411.4 |
|
Neurocrine Biosciences |
|
3 035 000 |
|
(19 600) |
|
3 015 400 |
|
USD |
|
85.17 |
|
234.5 |
|
257.5 |
|
Vertex Pharmaceuticals |
|
900 000 |
|
130 000 |
|
1 030 000 |
|
USD |
|
219.60 |
|
206.5 |
|
188.3 |
|
Fate Therapeutics |
|
2 030 000 |
|
1 671 336 |
|
3 701 336 |
|
USD |
|
58.51 |
|
197.7 |
|
163.4 |
|
Incyte |
|
2 900 000 |
|
(3 000) |
|
2 897 000 |
|
USD |
|
73.40 |
|
194.1 |
|
223.3 |
|
Alnylam Pharmaceuticals |
|
1 155 000 |
|
(45 000) |
|
1 110 000 |
|
USD |
|
169.58 |
|
171.8 |
|
132.9 |
|
Intra-Cellular Therapies |
|
3 538 419 |
|
– |
|
3 538 419 |
|
USD |
|
52.34 |
|
169.1 |
|
99.6 |
|
Arvinas |
|
2 176 903 |
|
– |
|
2 176 903 |
|
USD |
|
82.14 |
|
163.2 |
|
163.7 |
|
Agios Pharmaceuticals |
|
4 158 902 |
|
153 390 |
|
4 312 292 |
|
USD |
|
32.87 |
|
129.4 |
|
159.5 |
|
Sage Therapeutics |
|
1 540 104 |
|
1 630 000 |
|
3 170 104 |
|
USD |
|
42.54 |
|
123.1 |
|
117.9 |
|
Relay Therapeutics |
|
1 409 357 |
|
2 676 605 |
|
4 085 962 |
|
USD |
|
30.71 |
|
114.6 |
|
51.8 |
|
Biogen |
|
537 000 |
|
(37 000) |
|
500 000 |
|
USD |
|
239.92 |
|
109.5 |
|
116.4 |
|
Macrogenics |
|
4 815 564 |
|
2 460 000 |
|
7 275 564 |
|
USD |
|
16.05 |
|
106.6 |
|
97.4 |
|
Myovant Sciences |
|
4 757 039 |
|
1 365 000 |
|
6 122 039 |
|
USD |
|
15.57 |
|
87.0 |
|
116.3 |
|
Revolution Medicines |
|
– |
|
3 421 462 |
|
3 421 462 |
|
USD |
|
25.17 |
|
78.6 |
|
– |
|
Kezar Life Sciences |
|
4 533 148 |
|
385 000 |
|
4 918 148 |
|
USD |
|
16.72 |
|
75.1 |
|
20.9 |
|
Crispr Therapeutics |
|
900 884 |
|
48 700 |
|
949 584 |
|
USD |
|
75.78 |
|
65.7 |
|
122.1 |
|
Essa Pharma |
|
– |
|
5 015 814 |
|
5 015 814 |
|
USD |
|
14.20 |
|
65.0 |
|
– |
|
Scholar Rock Holding |
|
2 255 651 |
|
19 474 |
|
2 275 125 |
|
USD |
|
24.84 |
|
51.6 |
|
96.9 |
|
Radius Health |
|
7 455 714 |
|
250 000 |
|
7 705 714 |
|
USD |
|
6.92 |
|
48.7 |
|
117.9 |
|
Exelixis |
|
2 835 000 |
|
– |
|
2 835 000 |
|
USD |
|
18.28 |
|
47.3 |
|
50.4 |
|
Beam Therapeutics |
|
396 821 |
|
210 000 |
|
606 821 |
|
USD |
|
79.69 |
|
44.1 |
|
28.7 |
|
Molecular Templates |
|
6 380 331 |
|
4 411 672 |
|
10 792 003 |
|
USD |
|
3.92 |
|
38.6 |
|
53.0 |
|
Nektar Therapeutics |
|
2 620 676 |
|
– |
|
2 620 676 |
|
USD |
|
13.51 |
|
32.3 |
|
39.4 |
|
Generation Bio Co. |
|
2 333 180 |
|
1 520 000 |
|
3 853 180 |
|
USD |
|
7.08 |
|
24.9 |
|
58.6 |
|
Mersana Therapeutics |
|
1 885 000 |
|
2 250 000 |
|
4 135 000 |
|
USD |
|
6.22 |
|
23.5 |
|
44.4 |
|
Esperion Therapeutics |
|
3 947 964 |
|
530 000 |
|
4 477 964 |
|
USD |
|
5.00 |
|
20.4 |
|
90.9 |
|
Black Diamond Therapeutics |
|
1 390 000 |
|
2 050 000 |
|
3 440 000 |
|
USD |
|
5.33 |
|
16.7 |
|
39.4 |
|
Wave Life Sciences |
|
2 602 858 |
|
2 000 000 |
|
4 602 858 |
|
USD |
|
3.14 |
|
13.2 |
|
18.1 |
|
Homology Medicines |
|
1 737 122 |
|
– |
|
1 737 122 |
|
USD |
|
3.64 |
|
5.8 |
|
17.4 |
|
Alexion Pharmaceuticals |
|
1 294 428 |
|
(1 294 428) |
|
– |
|
USD |
|
n.a. |
|
– |
|
179.0 |
|
Halozyme Therapeutics |
|
3 970 000 |
|
(3 970 000) |
|
– |
|
USD |
|
n.a. |
|
– |
|
150.1 |
|
Voyager Therapeutics |
|
2 680 283 |
|
(2 680 283) |
|
– |
|
USD |
|
n.a. |
|
– |
|
17.0 |
|
Cidara Therapeutics |
|
2 822 495 |
|
(2 822 495) |
|
– |
|
USD |
|
n.a. |
|
– |
|
5.0 |
|
Total shares |
|
|
|
|
|
|
|
|
|
|
|
3 638.9 |
|
3 952.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Alder Biopharmaceuticals – Contingent Value Right |
|
2 766 008 |
|
– |
|
2 766 008 |
|
USD |
|
0.88 |
|
2.2 |
|
2.2 |
|
Bristol-Myers Squibb – Contingent Value Right |
|
800 000 |
|
(800 000) |
|
– |
|
USD |
|
n.a. |
|
– |
|
– |
|
Total derivative instruments |
|
|
|
|
|
|
|
|
|
|
|
2.2 |
|
2.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Total securities |
|
|
|
|
|
|
|
|
|
|
|
3 641.1 |
|
3 954.7 |
Securities are deposited with Bank Julius Baer & Co. Ltd., Zurich.
5. Short-term borrowings from banks
At December 31, 2021, a CHF 355 mn short-term loan is outstanding, with interest payable at 0.40% p.a. (2020: CHF 63 mn at 0.40% p.a.).
6. Other short-term liabilities
Other short-term liabilities comprise the following:
|
in CHF 1 000 |
|
31.12.2021 |
|
31.12.2020 |
|
Payables to investment manager |
|
3 966 |
|
3 715 |
|
Other liabilities |
|
1 465 |
|
1 994 |
|
Total liabilities to third parties |
|
5 431 |
|
5 709 |
7. Shareholders’ equity
The share capital of the Company consists of 55.4 mn fully paid registered shares (2020: 55.4 mn registered shares) with a par value of CHF 0.20 each (2020: CHF 0.20). CHF 2.2 mn of the retained earnings (2020: CHF 2.2 mn) are undistributable.
| in CHF 1 000 | Share capital | Treasury shares | Retained earnings | Total | ||||
| Balances at January 1, 2020 |
|
|
|
|
||||
| Dividend |
|
|
( |
( |
||||
| Trade with treasury shares (incl. change in balance) |
|
( |
|
( |
||||
| Total comprehensive income for the year |
|
|
|
|
||||
| Balances at December 31, 2020 |
|
( |
|
|
||||
| Balances at January 1, 2021 |
|
( |
|
|
||||
| Dividend |
|
|
( |
( |
||||
| Trade with treasury shares (incl. change in balance) |
|
( |
|
|
||||
| Total comprehensive income for the year |
|
|
( |
( |
||||
| Balances at December 31, 2021 |
|
( |
|
|
At December 31, 2021 and 2020, the Company has neither authorized nor conditional capital.
Treasury shares
The Company can buy and sell treasury shares in accordance with the Company’s articles of association and Swiss company law and in compliance with the listing rules of the SIX Swiss Exchange. During the period from January 1, 2021, to December 31, 2021, the Company has purchased 110 336 treasury shares to the amount of TCHF 9 459 and 117 572 treasury shares to the amount of TCHF 9 653 were sold (01.01.–31.12.2020: Purchase of 114 998 treasury shares to the amount of TCHF 8 260 and 336 treasury shares to the amount of TCHF 20 were sold). As at December 31, 2021, the Company held in total 107 426 treasury shares (December 31, 2020: 114 662 shares). The treasury shares as at December 31, 2021, were treated as a deduction from the consolidated shareholders’ equity using cost values of TCHF 9 205 (December 31, 2020: TCHF 8 240).
Share buyback 2nd line (bought for cancellation)
The Board of Directors has approved the repurchase of a maximum of 5 540 000 own registered shares with a nominal value of CHF 0.20 each. The share buy-back program will run from April 12, 2019, until April 11, 2022, at the latest. Until December 31, 2021, no shares had been repurchased under this share buy-back program. A repurchase would take place via second trading line for the purpose of a subsequent capital reduction.
8. Administrative expenses
Administrative expenses comprise the following:
|
in CHF 1 000 |
|
2021 |
|
2020 |
|
Investment manager |
|
|
|
|
|
– Management fees (incl. VAT) |
|
50 681 |
|
39 811 |
|
Personnel |
|
|
|
|
|
– Board of Directors remuneration |
|
1 288 |
|
1 223 |
|
– Wages and salaries |
|
525 |
|
593 |
|
– Social insurance contributions and duties |
|
101 |
|
128 |
|
|
|
52 595 |
|
41 755 |
The remuneration model of BB Biotech AG is determined by the Board of Directors.
Since 2014, the remuneration paid to the investment manager is based upon a 1.1% p.a. all-in fee on the average market capitalization without any additional fixed or performance-based elements of compensation, which is paid on a monthly basis. The compensation of the Board of Directors consists since 2014 of a fixed compensation.
9. Other expenses
Other expenses comprise the following:
|
in CHF 1 000 |
|
2021 |
|
2020 |
|
Bank charges |
|
644 |
|
551 |
|
Marketing and financial reporting |
|
1 293 |
|
1 613 |
|
Legal and consulting expenses |
|
524 |
|
357 |
|
Transaction costs |
|
2 772 |
|
2 433 |
|
Other expenses |
|
1 374 |
|
1 086 |
|
|
|
6 607 |
|
6 040 |
10. Taxes
|
in CHF 1 000 |
|
2021 |
|
2020 |
|
Operating income before tax |
|
(404 741) |
|
691 249 |
|
Expected tax rate (Direct federal, cantonal and communal tax) |
|
14.3% |
|
14.5% |
|
Expected income tax |
|
(57 878) |
|
100 231 |
|
Difference between effective local tax rates and the expected Swiss tax rate |
|
(57 945) |
|
100 156 |
|
Total income tax |
|
67 |
|
75 |
In the current year, the average effective income tax rate on a consolidated basis was less than 1% (2020: <1%). This low rate is mainly attributable to the fact that a large proportion of operating income was generated by companies located in Curaçao. As at December 31, 2021, there is no nettable loss carry forward (2020: none).
11. Earnings per share
|
|
|
2021 |
|
2020 |
|
Total comprehensive profit/(loss) for the period (in CHF 1 000) |
|
(404 808) |
|
691 174 |
|
Weighted average number of shares in issue |
|
55 363 670 |
|
55 391 180 |
|
Income per share in CHF |
|
(7.31) |
|
12.48 |
|
|
|
|
|
|
|
Income used to determine diluted income per share (in CHF 1 000) |
|
(404 808) |
|
691 174 |
|
Weighted average number of shares in issue following the dilution |
|
55 363 670 |
|
55 391 180 |
|
Diluted income per share in CHF |
|
(7.31) |
|
12.48 |
12. Segment reporting
The sole operating segment of the Group reflects the internal management structure and is evaluated on an overall basis. Revenue is derived by investing in a portfolio of companies active in the biotechnology industry for the purpose of capital appreciation. The following results correspond to the sole operating segment of investing in companies active in the biotechnology industry.
The geographical analysis of the profit/(loss) before tax is as follows – all income from financial assets are attributed to a country based on the domiciliation of the issuer of the instrument:
|
Profit/(loss) before tax in CHF 1 000 |
|
2021 |
|
2020 |
|
Netherlands |
|
60 946 |
|
100 499 |
|
Singapore |
|
(13 003) |
|
(2 039) |
|
Canada |
|
(29 966) |
|
– |
|
Great Britain |
|
(54 533) |
|
50 299 |
|
Curaçao |
|
(54 726) |
|
(43 634) |
|
Switzerland |
|
(61 874) |
|
70 632 |
|
USA |
|
(251 585) |
|
515 492 |
|
|
|
(404 741) |
|
691 249 |
13. Assets pledged
At December 31, 2021, the securities in the amount of CHF 3 641.1 mn (2020: CHF 3 954.7 mn) are a collateral for a credit line of CHF 700 mn (2020: CHF 700 mn). At December 31, 2021, a CHF 355 mn short-term loan is outstanding (2020: CHF 63 mn).
14. Commitments, contingencies and other off-balance sheet transactions
The Group had no commitments or other off-balance sheet transactions open at December 31, 2021 (2020: none).
The operations of the Group are affected by legislative, fiscal and regulatory developments for which provisions are made where deemed necessary. The Board of Directors concludes that as at December 31, 2021, no proceedings existed which could have any material effect on the financial position of the Group (2020: none).
15. Financial instruments by category
Financial assets and liabilities are allocated to categories as follows (in CHF 1 000):
|
At December 31, 2021 |
|
Financial assets at amortized cost |
|
Financial assets at fair value through profit or loss |
|
Total |
|
Assets as per balance sheet |
|
|
|
|
|
|
|
Cash and cash equivalents |
|
2 835 |
|
– |
|
2 835 |
|
Securities |
|
– |
|
3 641 112 |
|
3 641 112 |
|
|
|
2 835 |
|
3 641 112 |
|
3 643 947 |
|
|
|
|
|
|
|
|
|
|
|
Financial liabilities at fair value through profit or loss |
|
Financial liabilities at amortized cost |
|
Total |
|
Liabilities as per balance sheet |
|
|
|
|
|
|
|
Short-term borrowings from banks |
|
– |
|
355 000 |
|
355 000 |
|
Other short-term liabilities |
|
– |
|
5 431 |
|
5 431 |
|
|
|
– |
|
360 431 |
|
360 431 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
At December 31, 2020 |
|
Financial assets at amortized cost |
|
Financial assets at fair value through profit or loss |
|
Total |
|
Assets as per balance sheet |
|
|
|
|
|
|
|
Cash and cash equivalents |
|
6 816 |
|
– |
|
6 816 |
|
Receivables from brokers |
|
1 521 |
|
– |
|
1 521 |
|
Securities |
|
– |
|
3 954 659 |
|
3 954 659 |
|
|
|
8 337 |
|
3 954 659 |
|
3 962 996 |
|
|
|
|
|
|
|
|
|
|
|
Financial liabilities at fair value through profit or loss |
|
Financial liabilities at amortized cost |
|
Total |
|
Liabilities as per balance sheet |
|
|
|
|
|
|
|
Short-term borrowings from banks |
|
– |
|
63 000 |
|
63 000 |
|
Payables to brokers |
|
– |
|
6 576 |
|
6 576 |
|
Other short-term liabilities |
|
– |
|
5 709 |
|
5 709 |
|
|
|
– |
|
75 285 |
|
75 285 |
Profit and loss from financial assets and liabilities are allocated to categories as follows (in CHF 1 000):
|
2021 |
|
Financial assets at amortized cost |
|
Financial instruments at fair value through profit or loss |
|
Financial liabilities at amortized cost |
|
Total |
|
Profit and loss from financial instruments |
|
|
|
|
|
|
|
|
|
Net losses from securities |
|
– |
|
(343 595) |
|
– |
|
(343 595) |
|
Finance expenses |
|
– |
|
– |
|
(986) |
|
(986) |
|
Foreign exchange losses |
|
(962) |
|
– |
|
– |
|
(962) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2020 |
|
|
|
|
|
|
|
|
|
Profit and loss from financial instruments |
|
|
|
|
|
|
|
|
|
Net gains from securities |
|
– |
|
741 511 |
|
– |
|
741 511 |
|
Interest income |
|
7 |
|
– |
|
– |
|
7 |
|
Dividend income |
|
– |
|
243 |
|
– |
|
243 |
|
Finance expenses |
|
– |
|
– |
|
(883) |
|
(883) |
|
Foreign exchange losses |
|
(1 857) |
|
– |
|
– |
|
(1 857) |
16. Transactions with the Investment Manager and related party transactions
The investment management and administration of the Company has been delegated to Bellevue Asset Management AG. Based on the 1.1% p.a. all-in fee model, no additional costs incurred at Bellevue Asset Management AG were charged to the BB Biotech Group (2020: none). The amounts outstanding at the balance sheet date are disclosed in note 6, «Other short-term liabilities».
17. Significant shareholders
The Board of Directors is not aware of any major shareholder with a holding exceeding 3% of all votes as at December 31, 2021 and 2020.
18. Subsequent events
There have been no events subsequent to December 31, 2021, which would affect the 2021 consolidated financial statements.
Report on the audit of the consolidated financial statements
Report of the statutory auditor to the General Meeting of BB Biotech AG
Opinion
We have audited the consolidated financial statements of BB Biotech AG and its subsidiaries (the Group), which comprise the consolidated balance sheet as at 31 December 2021 and the consolidated statement of comprehensive income, consolidated statement of changes in equity and consolidated statement of cash flow for the year then ended, and notes to the consolidated financial statements, including a summary of significant accounting policies.
In our opinion, the consolidated financial statements give a true and fair view of the consolidated financial position of the Group as at 31 December 2021 and its consolidated financial performance and its consolidated cash flows for the year then ended in accordance with the International Financial Reporting Standards (IFRS) and comply with the provisions of article 14 of the Directive on Financial Reporting (DFR) of SIX Swiss Exchange and with Swiss law.
Basis for opinion
We conducted our audit in accordance with Swiss law, International Standards on Auditing (ISAs) and Swiss Auditing Standards. Our responsibilities under those provisions and standards are further described in the «Auditor’s responsibilities for the audit of the consolidated financial statements» section of our report.
We are independent of the Group in accordance with the provisions of Swiss law and the requirements of the Swiss audit profession, as well as the International Code of Ethics for Professional Accountants (including International Independence Standards) of the International Ethics Standards Board for Accountants (IESBA Code), and we have fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.
Our audit approach
Overview
Overall Group materiality: CHF 32 834 930
We concluded full scope audit work at all of the Group entities, which are located in
Our audit scope therefore addressed 100% of the Group’s assets, liabilities, equity, income, expenses and cash flows.
As key audit matters, the following areas of focus were identified:
- Valuation of securities
- Ownership of securities
Materiality
The scope of our audit was influenced by our application of materiality. Our audit opinion aims to provide reasonable assurance that the consolidated financial statements are free from material misstatement. Misstatements may arise due to fraud or error. They are considered material if, individually or in aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of the consolidated financial statements.
Based on our professional judgement, we determined certain quantitative thresholds for materiality, including the overall Group materiality for the consolidated financial statements as a whole as set out in the table below. These, together with qualitative considerations, helped us to determine the scope of our audit and the nature, timing and extent of our audit procedures and to evaluate the effect of misstatements, both individually and in aggregate, on the consolidated financial statements as a whole.
Overall Group materiality
CHF 32 834 930
How we determined it
1% of total consolidated shareholders’ equity
Rationale for the materiality benchmark applied
We chose shareholders’ consolidated equity as the benchmark because, in our view, it is the most relevant benchmark for investors, and it is a generally accepted benchmark for investment companies.
Audit scope
We designed our audit by determining materiality and assessing the risks of material misstatement in the consolidated financial statements. In particular, we considered where subjective judgements were made; for example, in respect of significant accounting estimates that involved making assumptions and considering future events that are inherently uncertain. As in all of our audits, we also addressed the risk of management override of internal controls, including among other matters consideration of whether there was evidence of bias that represented a risk of material misstatement due to fraud.
We tailored the scope of our audit in order to perform sufficient work to enable us to provide an opinion on the consolidated financial statements as a whole, taking into account the structure of the Group, the accounting processes and controls, and the industry in which the Group operates.
Key audit matters
Key audit matters are those matters that, in our professional judgement, were of most significance in our audit of the consolidated financial statements of the current period. These matters were addressed in the context of our audit of the consolidated financial statements as a whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters.
Valuation of securities
Key audit matter
The investment portfolio as of 31 December 2021 comprises investments in marketable and non-marketable securities (derivatives).
We consider this area to be a key audit matter because of the significant value of the securities in the consolidated financial statements.
As set out in note 4 (Schedule of securities) securities amount to CHF 3 641 million or 99.9% of total assets.
The valuation of the securities is prepared by the Investment Manager using the valuation methods disclosed in note 2 (Accounting policies). The Board of Directors approves the valuation of the investment portfolio.
How our audit addressed the key audit matter
We verified the design and implementation of the controls relating to the valuation of securities in order to determine whether the Investment Manager has appropriate controls in place. Further, we verified the adequacy of the applied valuation methods as well as the appropriateness of the resulting valuations by performing the following procedures:
We compared the valuation methods applied by the Investment Manager with generally accepted valuation methods. Further, we verified the quoted prices of marketable securities by comparing them with those from an independent source different from that used by the Investment Manager. Additionally, we verified that the valuation of the non-marketable securities is in line with the valuation policies of the Group.
We obtained sufficient audit evidence to conclude that the valuation methods were both appropriate and consistently applied by the Investment Manager.
Ownership of securities
Key audit matter
The securities are safeguarded by an independent custodian.
There is a risk that the Group may not have sufficient legal entitlement to the securities.
We consider this area to be a key audit matter because of the significant value of the securities in the consolidated financial statements.
How our audit addressed the key audit matter
We examined the ownership of the securities by requesting a confirmation of the securities portfolio directly from the custodian.
We obtained sufficient audit evidence to conclude that there is sufficient legal entitlement to the securities portfolio.
Other information in the annual report
The Board of Directors is responsible for the other information in the annual report. The other information comprises all information included in the annual report, but does not include the consolidated financial statements, the stand-alone financial statements and the remuneration report of BB Biotech AG and our auditor’s reports thereon.
Our opinion on the consolidated financial statements does not cover the other information in the annual report and we do not express any form of assurance conclusion thereon.
In connection with our audit of the consolidated financial statements, our responsibility is to read the other information in the annual report and, in doing so, consider whether the other information is materially inconsistent with the consolidated financial statements or our knowledge obtained in the audit, or otherwise appears to be materially misstated. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact. We have nothing to report in this regard.
Responsibilities of the Board of Directors for the consolidated financial statements
The Board of Directors is responsible for the preparation of the consolidated financial statements that give a true and fair view in accordance with IFRS, article 14 of the Directive on Financial Reporting (DFR) of SIX Swiss Exchange and the provisions of Swiss law, and for such internal control as the Board of Directors determines is necessary to enable the preparation of consolidated financial statements that are free from material misstatement, whether due to fraud or error.
In preparing the consolidated financial statements, the Board of Directors is responsible for assessing the Group’s ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the Board of Directors either intends to liquidate the Group or to cease operations, or has no realistic alternative but to do so.
Auditor’s responsibilities for the audit of the consolidated financial statements
Our objectives are to obtain reasonable assurance about whether the consolidated financial statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with Swiss law, ISAs and Swiss Auditing Standards will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these consolidated financial statements.
A further description of our responsibilities for the audit of the consolidated financial statements is located at the website of EXPERTsuisse: http://expertsuisse.ch/en/audit-report-for-public-companies. This description forms part of our auditor’s report.
Report on other legal and regulatory requirements
In accordance with article 728a paragraph 1 item 3 CO and Swiss Auditing Standard 890, we confirm that an internal control system exists which has been designed for the preparation of consolidated financial statements according to the instructions of the Board of Directors.
We recommend that the consolidated financial statements submitted to you be approved.
PricewaterhouseCoopers AG
Philippe Bingert
Audit expert
Auditor in charge
Roland Holl
Audit expert
Zurich, 16 February 2022
PricewaterhouseCoopers AG, Birchstrasse 160, Postfach, CH-8050 Zürich, Switzerland
Phone: +41 58 792 44 00, Fax: +41 58 792 44 10, www.pwc.ch
PricewaterhouseCoopers AG is a member of the global PricewaterhouseCoopers network of firms, each of which is a separate and independent legal entity.