<?xml version="1.0" encoding="utf-8"?>
<xs:schema xmlns:easyjetplc="http://easyjetplc.com/xbrl/2021" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" targetNamespace="http://easyjetplc.com/xbrl/2021" xmlns:xs="http://www.w3.org/2001/XMLSchema">
  <xs:import schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd" namespace="http://www.xbrl.org/2003/instance" />
  <xs:import schemaLocation="http://www.esma.europa.eu/taxonomy/2021-03-24/esef_cor.xsd" namespace="http://www.esma.europa.eu/taxonomy/2021-03-24/esef_cor" />
  <xs:import schemaLocation="http://www.xbrl.org/lrr/arcrole/esma-arcrole-2018-11-21.xsd" namespace="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" />
  <xs:import schemaLocation="http://www.xbrl.org/dtr/type/nonNumeric-2009-12-16.xsd" namespace="http://www.xbrl.org/dtr/type/non-numeric" />
  <xs:import schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd" namespace="http://xbrl.org/2005/xbrldt" />
  <xs:annotation>
    <xs:appinfo>
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="easyjetplc-2022-09-30_lab-en.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple" />
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="easyjetplc-2022-09-30_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple" />
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="easyjetplc-2022-09-30_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple" />
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="easyjetplc-2022-09-30_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple" />
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="http://www.esma.europa.eu/taxonomy/2021-03-24/esef_cor-lab-en.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple" />
      <link:linkbaseRef xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="http://www.esma.europa.eu/taxonomy/2021-03-24/esef_cor-gen-en.xml" xlink:type="simple" />
      <link:roleType id="Anchoring" roleURI="http://easyjetplc.com/xbrl/2021/roles/Anchoring">
        <link:definition>99 - Groups all anchored elements</link:definition>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ProfitOrLoss" roleURI="http://easyjetplc.com/xbrl/2021/roles/ProfitOrLoss">
        <link:definition>01 - Profit or loss</link:definition>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementOfComprehensiveIncome" roleURI="http://easyjetplc.com/xbrl/2021/roles/StatementOfComprehensiveIncome">
        <link:definition>02 - Statement of comprehensive income</link:definition>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementOfFinancialPosition" roleURI="http://easyjetplc.com/xbrl/2021/roles/StatementOfFinancialPosition">
        <link:definition>03 - Statement of financial position</link:definition>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementOfChangesInEquity" roleURI="http://easyjetplc.com/xbrl/2021/roles/StatementOfChangesInEquity">
        <link:definition>04 - Statement of changes in equity</link:definition>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementOfChangesInEquityParenthetical" roleURI="http://easyjetplc.com/xbrl/2021/roles/StatementOfChangesInEquityParenthetical">
        <link:definition>05 - Statement of changes in equity (Parenthetical)</link:definition>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StatementOfCashFlows" roleURI="http://easyjetplc.com/xbrl/2021/roles/StatementOfCashFlows">
        <link:definition>06 - Statement of cash flows</link:definition>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
      <link:roleType id="NotesAndMandatoryItems" roleURI="http://easyjetplc.com/xbrl/2021/roles/NotesAndMandatoryItems">
        <link:definition>07 - Notes and Mandatory Items</link:definition>
        <link:usedOn>link:definitionLink</link:usedOn>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:labelLink</link:usedOn>
      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="easyjetplc_ConsolidatedIncomeStatementAxis" xbrli:periodType="duration" abstract="true" name="ConsolidatedIncomeStatementAxis" nillable="true" xmlns:q1="http://xbrl.org/2005/xbrldt" substitutionGroup="q1:dimensionItem" type="xbrli:stringItemType" />
  <xs:element id="easyjetplc_HeadlineMember" xbrli:periodType="duration" abstract="true" name="HeadlineMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" />
  <xs:element id="easyjetplc_NonHeadlineMember" xbrli:periodType="duration" abstract="true" name="NonHeadlineMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" />
  <xs:element id="easyjetplc_TotalMember" xbrli:periodType="duration" abstract="true" name="TotalMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" />
  <xs:element id="easyjetplc_ProfitOrLossTable" xbrli:periodType="duration" abstract="true" name="ProfitOrLossTable" nillable="true" xmlns:q2="http://xbrl.org/2005/xbrldt" substitutionGroup="q2:hypercubeItem" type="xbrli:stringItemType" />
  <xs:element id="easyjetplc_ProfitOrLossLineItems" xbrli:periodType="duration" abstract="true" name="ProfitOrLossLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" />
  <xs:element id="easyjetplc_AncillaryRevenue" xbrli:balance="credit" xbrli:periodType="duration" name="AncillaryRevenue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_AirportsGroundHandlingHolidayAccommodationAndOtherOperatingCosts" xbrli:balance="debit" xbrli:periodType="duration" name="AirportsGroundHandlingHolidayAccommodationAndOtherOperatingCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_Crew" xbrli:balance="debit" xbrli:periodType="duration" name="Crew" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_Navigation" xbrli:balance="debit" xbrli:periodType="duration" name="Navigation" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_EBITDAR" xbrli:balance="credit" xbrli:periodType="duration" name="EBITDAR" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_AircraftDryLeasing" xbrli:balance="debit" xbrli:periodType="duration" name="AircraftDryLeasing" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_HedgeDiscontinuationLossesTransferredToIncomeStatement" xbrli:balance="debit" xbrli:periodType="duration" name="HedgeDiscontinuationLossesTransferredToIncomeStatement" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_CostOfHedging" xbrli:balance="credit" xbrli:periodType="duration" name="CostOfHedging" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_RelatedTaxCredit" xbrli:balance="credit" xbrli:periodType="duration" name="RelatedTaxCredit" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_CurrentIntangibleAssets" xbrli:balance="debit" xbrli:periodType="instant" name="CurrentIntangibleAssets" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_MoneyMarketDeposits" xbrli:balance="debit" xbrli:periodType="instant" name="MoneyMarketDeposits" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_CurrentUnearnedRevenue" xbrli:balance="credit" xbrli:periodType="instant" name="CurrentUnearnedRevenue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_NonCurrentUnearnedRevenue" xbrli:balance="credit" xbrli:periodType="instant" name="NonCurrentUnearnedRevenue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_CostOfHedgingReserve" xbrli:balance="credit" xbrli:periodType="instant" name="CostOfHedgingReserve" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_CostOfHedgingReserveMember" xbrli:periodType="duration" abstract="true" name="CostOfHedgingReserveMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" />
  <xs:element id="easyjetplc_TransferToPropertyPlantAndEquipment" xbrli:balance="credit" xbrli:periodType="duration" name="TransferToPropertyPlantAndEquipment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_PurchaseOfOwnShares" xbrli:balance="debit" xbrli:periodType="duration" name="PurchaseOfOwnShares" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_CurrencyTranslationDifferences" xbrli:balance="credit" xbrli:periodType="duration" name="CurrencyTranslationDifferences" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_GrossProceedsFromRightsIssue" xbrli:balance="credit" xbrli:periodType="duration" name="GrossProceedsFromRightsIssue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_OutstandingProceedsFromRightsIssue" xbrli:balance="credit" xbrli:periodType="duration" name="OutstandingProceedsFromRightsIssue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_RightsIssueCosts" xbrli:balance="debit" xbrli:periodType="duration" name="RightsIssueCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_GainsLossesOnHedgingReserveRelatingToCrossCurrencyBasis" xbrli:balance="credit" xbrli:periodType="duration" name="GainsLossesOnHedgingReserveRelatingToCrossCurrencyBasis" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_GainsLossesOnhedgingReserveRelatingToTimeValueOfOptions" xbrli:balance="credit" xbrli:periodType="duration" name="GainsLossesOnhedgingReserveRelatingToTimeValueOfOptions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_SettlementOfDerivativesClassifiedAsOperatingActivities" xbrli:balance="credit" xbrli:periodType="duration" name="SettlementOfDerivativesClassifiedAsOperatingActivities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_NetDecreaseInMoneyMarketDepositsClassifiedAsInvestingActivities" xbrli:balance="debit" xbrli:periodType="duration" name="NetDecreaseInMoneyMarketDepositsClassifiedAsInvestingActivities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_NetProceedsFromSaleAndLeasebacksClassifiedAsInvestingActivities" xbrli:balance="debit" xbrli:periodType="duration" name="NetProceedsFromSaleAndLeasebacksClassifiedAsInvestingActivities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
  <xs:element id="easyjetplc_DecreaseIncreaseInRestrictedCashClassifiedAsFinancingActivities" xbrli:balance="debit" xbrli:periodType="duration" name="DecreaseIncreaseInRestrictedCashClassifiedAsFinancingActivities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" />
</xs:schema>